Vascular Cell Adhesion Molecule-1

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  Subject Areas on Research

  • A role of matrix metalloproteinase-8 in atherosclerosis. 
  • Acute host-mediated endothelial injury after adenoviral gene transfer in normal rabbit arteries: impact on transgene expression and endothelial function. 
  • Adhesion molecules, platelet activation, and cardiovascular risk. 
  • An inhibitor of IkappaB kinase, BMS-345541, blocks endothelial cell adhesion molecule expression and reduces the severity of dextran sulfate sodium-induced colitis in mice. 
  • Assessment of biomarkers of cardiovascular risk among HIV type 1-infected adolescents: role of soluble vascular cell adhesion molecule as an early indicator of endothelial inflammation. 
  • Assignment of transforming growth factor beta1 and beta3 and a third new ligand to the type I receptor ALK-1. 
  • Blood-derived macrophages infiltrate the retina and activate Muller glial cells under experimental choroidal neovascularization. 
  • CXCR4 enhances adhesion of B16 tumor cells to endothelial cells in vitro and in vivo via beta(1) integrin. 
  • Cell cycle-dependent regulation of smooth muscle cell activation. 
  • Characterization of skin cytokines in bullous pemphigoid and pemphigus vulgaris. 
  • Chronic Systemic Immune Dysfunction in African-Americans with Small Vessel-Type Ischemic Stroke. 
  • Circulating markers of inflammation and endothelial function, and their relationship to diabetic retinopathy. 
  • Clinical heterogeneity in hereditary haemorrhagic telangiectasia: are pulmonary arteriovenous malformations more common in families linked to endoglin? 
  • Cloning of the promoter region of human endoglin, the target gene for hereditary hemorrhagic telangiectasia type 1. 
  • Cytokine-induced mobilization of circulating endothelial progenitor cells enhances repair of injured arteries. 
  • Development of a multimarker assay for early detection of ovarian cancer. 
  • Direct-contact co-culture between smooth muscle and endothelial cells inhibits TNF-alpha-mediated endothelial cell activation. 
  • Elevations of inflammatory proteins in neonatal blood are associated with obesity and overweight among 2-year-old children born extremely premature. 
  • Endoglin gene polymorphism as a risk factor for sporadic intracerebral hemorrhage. 
  • Endoglin, a TGF-beta binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1. 
  • Endoglin, an ancillary TGFbeta receptor, is required for extraembryonic angiogenesis and plays a key role in heart development. 
  • Endothelial gene expression in regions of defined shear exposure in the porcine iliac arteries. 
  • Expression analysis of endoglin missense and truncation mutations: insights into protein structure and disease mechanisms. 
  • Expression analysis of four endoglin missense mutations suggests that haploinsufficiency is the predominant mechanism for hereditary hemorrhagic telangiectasia type 1. 
  • Focal increases in vascular cell adhesion molecule-1 and intimal macrophages at atherosclerosis-susceptible sites in the rabbit aorta after short-term cholesterol feeding. 
  • Genetic abnormalities in hereditary hemorrhagic telangiectasia. 
  • Genetic polymorphisms modify bladder cancer recurrence and survival in a USA population-based prognostic study. 
  • Hematolymphoid malignancies with intraocular intravascular involvement: report of 2 cases. 
  • Hemodynamic parameters and early intimal thickening in branching blood vessels. 
  • Hereditary haemorrhagic telangiectasia: a questionnaire based study to delineate the different phenotypes caused by endoglin and ALK1 mutations. 
  • Inhibition of T cell costimulation by VCAM-1 prevents murine graft-versus-host disease across minor histocompatibility barriers. 
  • Inhibition of endothelial activation: a new way to treat cerebral malaria? 
  • Interleukin-9 mediates chronic kidney disease-dependent vein graft disease: a role for mast cells. 
  • Intracellular adhesion molecule-1 modulates beta-chemokines and directly costimulates T cells in vivo. 
  • Knockdown of mouse VCAM-1 by vector-based siRNA. 
  • Microparticles in the blood of patients with systemic lupus erythematosus (SLE): phenotypic characterization and clinical associations. 
  • Molecular classification of patients with unexplained hamartomatous and hyperplastic polyposis. 
  • Monocyte attachment to activated human vascular endothelium in vitro is mediated by leukocyte adhesion molecule-1 (L-selectin) under nonstatic conditions. 
  • Monocyte rolling, arrest and spreading on IL-4-activated vascular endothelium under flow is mediated via sequential action of L-selectin, beta 1-integrins, and beta 2-integrins. 
  • Mutation and expression analysis of the endoglin gene in hereditary hemorrhagic telangiectasia reveals null alleles. 
  • Neutral effect on markers of heart failure, inflammation, endothelial activation and function, and vagal tone after high-dose HMG-CoA reductase inhibition in non-diabetic patients with non-ischemic cardiomyopathy and average low-density lipoprotein level. 
  • Novel diagnostic test for acute stroke. 
  • Phase I study of recombinant human endostatin in patients with advanced solid tumors. 
  • Phenotypic and functional differences between human saphenous vein (HSVEC) and umbilical vein (HUVEC) endothelial cells. 
  • Platelets promote pulmonary pull of polys. 
  • Polymorphisms in transforming growth factor-beta-related genes ALK1 and ENG are associated with sporadic brain arteriovenous malformations. 
  • Pro- and antiatherogenic effects of a dominant-negative P465L mutation of peroxisome proliferator-activated receptor-γ in apolipoprotein E-Null mice. 
  • RU486 blocks the anti-inflammatory effects of exercise in a murine model of allergen-induced pulmonary inflammation. 
  • Relations of a marker of endothelial activation (s-VCAM) to function and mortality in community-dwelling older adults. 
  • Residues within a conserved amino acid motif of domains 1 and 4 of VCAM-1 are required for binding to VLA-4. 
  • Signaling by the transforming growth factor-beta receptors. 
  • Six novel mutations in the endoglin gene in hereditary hemorrhagic telangiectasia type 1 suggest a dominant-negative effect of receptor function. 
  • Soluble VCAM-1 and E-selectin, but not ICAM-1 discriminate endothelial injury in patients with documented coronary artery disease. 
  • Soluble vascular cell adhesion molecule-1 and E-selectin in patients with acute myocardial infarction treated with thrombolytic agents. 
  • The NF-kappa B inhibitor, tepoxalin, suppresses surface expression of the cell adhesion molecules CD62E, CD11b/CD18 and CD106. 
  • The effect of chronic azithromycin therapy on soluble endothelium-derived adhesion molecules in patients with coronary artery disease. 
  • The molecular genetics of hereditary hemorrhagic telangiectasia. 
  • The role of adhesion molecules in human leukocyte attachment to porcine vascular endothelium: implications for xenotransplantation. 
  • Two common endoglin mutations in families with hereditary hemorrhagic telangiectasia in the Netherlands Antilles: evidence for a founder effect. 
  • Vascular endothelial growth factor induces abnormal microvasculature in the endoglin heterozygous mouse brain. 
  • Vascular morphogenesis: tales of two syndromes. 
  • Why sinonasal disease spares the inferior turbinate: An immunohistochemical analysis. 
  • [LMP-420, a new therapeutic approach for cerebral malaria?].