Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
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Subject Areas on Research
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A Genoproteomic Approach to Detect Peptide Markers of Bacterial Respiratory Pathogens.
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A general mass spectrometry-based assay for the quantitation of protein-ligand binding interactions in solution.
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A new H/D exchange- and mass spectrometry-based method for thermodynamic analysis of protein-DNA interactions.
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A proteomic analysis of human cilia: identification of novel components.
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A proteomic approach for dissecting H-Ras signaling networks in NIH/3T3 mouse embryonic fibroblast cells.
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A proteomic approach for unraveling the oncogenic H-Ras protein networks in NIH/3T3 mouse embryonic fibroblast cells.
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A quantitative, high-throughput screen for protein stability.
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A solid sample preparation method that reduces signal suppression effects in the MALDI analysis of peptides.
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A stable dimer in the pH-induced equilibrium unfolding of the homo-hexameric enzyme 4-oxalocrotonate tautomerase (4-OT).
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Accuracy and precision of a new H/D exchange- and mass spectrometry-based technique for measuring the thermodynamic properties of protein-peptide complexes.
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Accuracy of SUPREX (stability of unpurified proteins from rates of H/D exchange) and MALDI mass spectrometry-derived protein unfolding free energies determined under non-EX2 exchange conditions.
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Activation-dependent conformational changes in {beta}-arrestin 2.
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An obligately photosynthetic bacterial anaerobe from a deep-sea hydrothermal vent.
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Analysis of human serum proteins by liquid phase isoelectric focusing and matrix-assisted laser desorption/ionization-mass spectrometry.
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Avicinylation (thioesterification): a protein modification that can regulate the response to oxidative and nitrosative stress.
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BiPS, a photocleavable, isotopically coded, fluorescent cross-linker for structural proteomics.
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CCSP regulates cross talk between secretory cells and both ciliated cells and macrophages of the conducting airway.
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Capture of phosphopeptides using alpha-zirconium phosphate nanoplatelets.
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Carbonylation of adipose proteins in obesity and insulin resistance: identification of adipocyte fatty acid-binding protein as a cellular target of 4-hydroxynonenal.
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Characterization of the role of the amino-terminal proline in the enzymatic activity catalyzed by macrophage migration inhibitory factor.
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Combining MALDI-FTMS and bioinformatics for rapid peptidomic comparisons.
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Comparative analysis of small molecules and histone substrate analogues as LSD1 lysine demethylase inhibitors.
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Comparative proteomic analysis of differentially expressed proteins in β-aminobutyric acid enhanced Arabidopsis thaliana tolerance to simulated acid rain.
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Comparative proteomic analysis of proteins in response to simulated acid rain in Arabidopsis.
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Comparison of HPLC/ESI-FTICR MS versus MALDI-TOF/TOF MS for glycopeptide analysis of a highly glycosylated HIV envelope glycoprotein.
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Complexities associated with the molecular and proteomic identification of Paecilomyces species in the clinical mycology laboratory.
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Culture-negative prosthetic valve endocarditis with concomitant septicemia due to a nontoxigenic Corynebacterium diphtheriae biotype gravis isolate in a patient with multiple risk factors.
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Current trends in differential expression proteomics: isotopically coded tags.
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Cytokeratin 12 in human ocular surface epithelia is the antigen reactive with a commercial anti-Galpha q antibody.
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Diagnostic protein discovery using liquid chromatography/mass spectrometry for proteolytic peptide targeting.
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Diagnostic protein discovery using proteolytic peptide targeting and identification.
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Differential extraction and enrichment of human sperm surface proteins in a proteome: identification of immunocontraceptive candidates.
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Direct tandem mass spectrometry reveals limitations in protein profiling experiments for plasma biomarker discovery.
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Directed evolution of a new catalytic site in 2-keto-3-deoxy-6-phosphogluconate aldolase from Escherichia coli.
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Discovery and verification of protein differences between Er positive/Her2/neu negative breast tumor tissue and matched adjacent normal breast tissue.
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Discovery of biomarker candidates for coronary artery disease from an APOE-knock out mouse model using iTRAQ-based multiplex quantitative proteomics.
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Downregulation of a unique photoreceptor protein correlates with improper outer segment assembly.
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Effects of chemical inhibition of N-WASP, a critical regulator of actin polymerization on aqueous humor outflow through the conventional pathway.
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Elevation of intact and proteolytic fragments of acute phase proteins constitutes the earliest systemic antiviral response in HIV-1 infection.
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Energetics-based methods for protein folding and stability measurements.
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Enhancing Schwann cell migration using concentration gradients of laminin-derived peptides.
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Establishment of a high-efficiency SNP-based framework marker set for Arabidopsis.
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Evaluation of serum protein profiling by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry for the detection of prostate cancer: I. Assessment of platform reproducibility.
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Evaluation of the Vitek MS v3.0 Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry System for Identification of Mycobacterium and Nocardia Species.
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Evolution of graded refractive index in squid lenses.
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Ex vivo analysis of synergistic anion binding to FbpA in Gram-negative bacteria.
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Exploiting the complementary nature of LC/MALDI/MS/MS and LC/ESI/MS/MS for increased proteome coverage.
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Finding diagnostic biomarkers in proteomic spectra.
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Further insights into quinone cofactor biogenesis: probing the role of mauG in methylamine dehydrogenase tryptophan tryptophylquinone formation.
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Generating mammalian sirtuin tools for protein-interaction analysis.
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Genetic factors contribute to bleeding after cardiac surgery.
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Genetic polymorphisms of selected DNA repair genes, estrogen and progesterone receptor status, and breast cancer risk.
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Glycosylation site-specific analysis of HIV envelope proteins (JR-FL and CON-S) reveals major differences in glycosylation site occupancy, glycoform profiles, and antigenic epitopes' accessibility.
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H/D exchange and mass spectrometry-based method for biophysical analysis of multidomain proteins at the domain level.
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High-throughput screening assay for the tunable selection of protein ligands.
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Ibudilast sensitizes glioblastoma to temozolomide by targeting Macrophage Migration Inhibitory Factor (MIF).
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Identification and validation of a potential lung cancer serum biomarker detected by matrix-assisted laser desorption/ionization-time of flight spectra analysis.
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Identification of five hemoglobins in B6C3F1 mice by mass spectrometry and sequence analysis.
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Improved peak detection in mass spectrum by incorporating continuous wavelet transform-based pattern matching.
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Inflammatory protein profile during systemic high dose interleukin-2 administration.
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Lactobacillus reuteri DSM 20016 produces cobalamin-dependent diol dehydratase in metabolosomes and metabolizes 1,2-propanediol by disproportionation.
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Manganese (III) meso-tetrakis N-ethylpyridinium-2-yl porphyrin acts as a pro-oxidant to inhibit electron transport chain proteins, modulate bioenergetics, and enhance the response to chemotherapy in lymphoma cells.
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Mapping tertiary interactions in protein folding reactions: a novel mass spectrometry- and chemical synthesis-based approach.
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Mass spectrometry-based thermal shift assay for protein-ligand binding analysis.
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Measurements of protein stability by H/D exchange and matrix-assisted laser desorption/ionization mass spectrometry using picomoles of material.
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Mixed peptide sequencing and the FASTF/FASTS algorithms.
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New mass spectrometric assay for angiotensin-converting enzyme 2 activity.
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Overexpression of annexin a1 induced by terephthalic acid calculi in rat bladder cancer.
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PEGylated gold nanoparticles conjugated to monoclonal F19 antibodies as targeted labeling agents for human pancreatic carcinoma tissue.
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Pancreatic islets and insulinoma cells express a novel isoform of group VIA phospholipase A2 (iPLA2 beta) that participates in glucose-stimulated insulin secretion and is not produced by alternate splicing of the iPLA2 beta transcript.
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Plasma protein profiling for diagnosis of pancreatic cancer reveals the presence of host response proteins.
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Prion disease diagnosis by proteomic profiling.
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Probing the chemical basis of binding activity in an SH3 domain by protein signature analysis.
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Protein expression profiling identifies macrophage migration inhibitory factor and cyclophilin a as potential molecular targets in non-small cell lung cancer.
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Protein fragment domains identified using 2D gel electrophoresis/MALDI-TOF.
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Protein kinase activity of phosphoinositide 3-kinase regulates beta-adrenergic receptor endocytosis.
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Proteome analysis by mass spectrometry.
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Proteome analysis of the rat cornea during angiogenesis.
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Proteomic identification of specific oxidized proteins in ApoE-knockout mice: relevance to Alzheimer's disease.
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Protocol for the thermodynamic analysis of some proteins using an H/D exchange- and mass spectrometry-based technique.
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Psoralen Derivatives with Enhanced Potency.
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Quantitative protein stability measurement in vivo.
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Rapid and sensitive method for detection of Y402, H402, I62, and V62 variants of complement factor H in human plasma samples using mass spectrometry.
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Recombinant Synthesis of Hybrid Lipid-Peptide Polymer Fusions that Self-Assemble and Encapsulate Hydrophobic Drugs.
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Recursive directional ligation by plasmid reconstruction allows rapid and seamless cloning of oligomeric genes.
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Regulation of iron transport related genes by boron in the marine bacterium Marinobacter algicola DG893.
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Ring-Opening Copolymerization of Maleic Anhydride with Functional Epoxides: Poly(propylene fumarate) Analogues Capable of Post-Polymerization Modification.
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SUPREX (Stability of Unpurified Proteins from Rates of H/D Exchange) analysis of the thermodynamics of synergistic anion binding by ferric-binding protein (FbpA), a bacterial transferrin.
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Sample preparation for MALDI mass spectrometry using an elastomeric device reversibly sealed on the MALDI target.
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Scanning Quadrupole Data-Independent Acquisition, Part A: Qualitative and Quantitative Characterization.
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Scanning Quadrupole Data-Independent Acquisition, Part B: Application to the Analysis of the Calcineurin-Interacting Proteins during Treatment of Aspergillus fumigatus with Azole and Echinocandin Antifungal Drugs.
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Separation of peptides with polyionic nanosponges for MALDI-MS analysis.
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Signal Transducer and Activator of Transcription 3, Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer.
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Synthesis of oligonucleoside boranophosphates via an H-phosphonate method without nucleobase protection.
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The host defense peptide cathelicidin is required for NK cell-mediated suppression of tumor growth.
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Thermodynamic analysis of protein folding and stability using a tryptophan modification protocol.
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Thermodynamic analysis of protein stability and ligand binding using a chemical modification- and mass spectrometry-based strategy.
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Thermodynamic analysis of subunit interactions in Escherichia coli molybdopterin synthase.
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Thermodynamic stability measurements on multimeric proteins using a new H/D exchange- and matrix-assisted laser desorption/ionization (MALDI) mass spectrometry-based method.
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Thrittene, homologous with somatostatin-28((1-13)), is a novel peptide in mammalian gut and circulation.
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Throughput and efficiency of a mass spectrometry-based screening assay for protein-ligand binding detection.
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Transformation of alkylating regimen of thiotepa into tepa determines the disease progression through GSTP1 gene polymorphism for metastatic breast cancer patients receiving thiotepa containing salvage chemotherapy.
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Transient opening of fibronectin type III (FNIII) domains: the interaction of the third FNIII domain of FN with anastellin.
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Turnip yellow mosaic virus as a chemoaddressable bionanoparticle.
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Unique Intradural Inflammatory Mass Containing Precipitated Morphine: Confirmatory Analysis by LESA-MS and MALDI-MS.
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Validation of DNA methylation biomarkers for diagnosis of acute lymphoblastic leukemia.
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XPO1/CRM1 Inhibition Causes Antitumor Effects by Mitochondrial Accumulation of eIF5A.
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trans-2-Phenylcyclopropylamine is a mechanism-based inactivator of the histone demethylase LSD1.
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Keywords of People