Prostatic Intraepithelial Neoplasia
Subject Areas on Research
- CD34 immunohistochemical assessment of angiogenesis as a prognostic marker for prostate cancer recurrence after radical prostatectomy.
- Deletion of the p16INK4a tumor suppressor and expression of the androgen receptor induce sarcomatoid carcinomas with signet ring cells in the mouse prostate.
- Expression of p14ARF, p15INK4b, p16INK4a, and DCR2 increases during prostate cancer progression.
- Hyperglycemia and T Cell infiltration are associated with stromal and epithelial prostatic hyperplasia in the nonobese diabetic mouse.
- Identification of a cell of origin for human prostate cancer.
- Loss of heterozygosity of M6P/IGF2R gene is an early event in the development of prostate cancer.
- Ornithine Decarboxylase Is Sufficient for Prostate Tumorigenesis via Androgen Receptor Signaling.
- Phase III trial of selenium to prevent prostate cancer in men with high-grade prostatic intraepithelial neoplasia: SWOG S9917.
- Prohibitin mutations are uncommon in prostate cancer families linked to chromosome 17q.
- Prostate intraepithelial neoplasia induced by prostate restricted Akt activation: the MPAKT model.
- Role of autonomous androgen receptor signaling in prostate cancer initiation is dichotomous and depends on the oncogenic signal.
- Somatic single hits inactivate the X-linked tumor suppressor FOXP3 in the prostate.
- Stromal epigenetic dysregulation is sufficient to initiate mouse prostate cancer via paracrine Wnt signaling.
- The comprehensive role of E-cadherin in maintaining prostatic epithelial integrity during oncogenic transformation and tumor progression.
- The role of WNT10B in normal prostate gland development and prostate cancer.
- U19/Eaf2 knockout causes lung adenocarcinoma, B-cell lymphoma, hepatocellular carcinoma and prostatic intraepithelial neoplasia.