Virus Assembly
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Subject Areas on Research
- A novel immunocompetent murine tumor model for the evaluation of RCAd-enhanced RDAd transduction efficacy.
- A viral genome packaging motor transitions between cyclic and helical symmetry to translocate dsDNA.
- Bioluminescent virion shells: new tools for quantitation of AAV vector dynamics in cells and live animals.
- Colocalization of different influenza viral RNA segments in the cytoplasm before viral budding as shown by single-molecule sensitivity FISH analysis.
- Cooperation between the Hepatitis C Virus p7 and NS5B Proteins Enhances Virion Infectivity.
- Cross-dressing the virion: the transcapsidation of adeno-associated virus serotypes functionally defines subgroups.
- Determination of the cleavage site of enterovirus 71 VP0 and the effect of this cleavage on viral infectivity and assembly.
- Evidence that a catalytic glutamate and an 'Arginine Toggle' act in concert to mediate ATP hydrolysis and mechanochemical coupling in a viral DNA packaging motor.
- Functional Dissection of a Viral DNA Packaging Machine's Walker B Motif.
- Functional analysis of the simian immunodeficiency virus Vpx protein: identification of packaging determinants and a novel nuclear targeting domain.
- Human immunodeficiency virus type 1 resistance to the small molecule maturation inhibitor 3-O-(3',3'-dimethylsuccinyl)-betulinic acid is conferred by a variety of single amino acid substitutions at the CA-SP1 cleavage site in Gag.
- Hunting coronavirus by transmission electron microscopy - a guide to SARS-CoV-2-associated ultrastructural pathology in COVID-19 tissues.
- Influenza viruses that require 10 genomic segments as antiviral therapeutics.
- Mapping and Engineering Functional Domains of the Assembly-Activating Protein of Adeno-associated Viruses.
- Measuring Hepatitis C Virus Envelopment by Using a Proteinase K Protection Assay.
- Molecular determinants and dynamics of hepatitis C virus secretion.
- Molecular interactions and residues involved in force generation in the T4 viral DNA packaging motor.
- Nelfinavir inhibits maturation and export of herpes simplex virus 1.
- Packaging of an AAV vector encoding human acid alpha-glucosidase for gene therapy in glycogen storage disease type II with a modified hybrid adenovirus-AAV vector.
- Pervasive tertiary structure in the dengue virus RNA genome.
- Protection of neonatal macaques against experimental SHIV infection by human neutralizing monoclonal antibodies.
- The acidic domain of the hepatitis C virus NS4A protein is required for viral assembly and envelopment through interactions with the viral E1 glycoprotein.
- Virus particle release from glycosphingolipid-enriched microdomains is essential for dendritic cell-mediated capture and transfer of HIV-1 and henipavirus.
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Keywords of People
- Arya, Gaurav, Professor in the Thomas Lord Department of Mechanical Engineering and Materials Science, Pratt School of Engineering