GTP-Binding Protein alpha Subunits, Gs
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Subject Areas on Research
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A Gαs DREADD mouse for selective modulation of cAMP production in striatopallidal neurons.
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Adaptive Activation of a Stress Response Pathway Improves Learning and Memory Through Gs and β-Arrestin-1-Regulated Lactate Metabolism.
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Adrenergic receptor function in panic disorder. II. Neutrophil beta 2 receptors: Gs protein coupling, effects of imipramine treatment and relationship to treatment outcome.
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Androgen receptor activation by G(s) signaling in prostate cancer cells.
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Arc/Arg3.1 translation is controlled by convergent N-methyl-D-aspartate and Gs-coupled receptor signaling pathways.
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Beta(2)-adrenergic and several other G protein-coupled receptors in human atrial membranes activate both G(s) and G(i).
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Beta-adrenoceptor control of G protein function in the neonate: determinant of desensitization or sensitization.
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Central nervous system imprinting of the G protein G(s)alpha and its role in metabolic regulation.
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Chronic loss of noradrenergic tone produces β-arrestin2-mediated cocaine hypersensitivity and alters cellular D2 responses in the nucleus accumbens.
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Cryo-EM structure of human rhodopsin bound to an inhibitory G protein.
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Design, synthesis, and functional assessment of Cmpd-15 derivatives as negative allosteric modulators for the β2-adrenergic receptor.
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G(s)alpha deficiency in adipose tissue leads to a lean phenotype with divergent effects on cold tolerance and diet-induced thermogenesis.
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G(s)alpha deficiency in skeletal muscle leads to reduced muscle mass, fiber-type switching, and glucose intolerance without insulin resistance or deficiency.
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GNAS and KRAS Mutations Define Separate Progression Pathways in Intraductal Papillary Mucinous Neoplasm-Associated Carcinoma.
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GNAS mutations identify a set of right-sided, RAS mutant, villous colon cancers.
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GNAS sequencing identifies IPMN-specific mutations in a subgroup of diminutive pancreatic cysts referred to as "incipient IPMNs".
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GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling.
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Gorlin syndrome and desmoplastic medulloblastoma: Report of 3 cases with unfavorable clinical course and novel mutations.
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Gαs proteins activate p72(Syk) and p60-c-Src tyrosine kinases to mediate sickle red blood cell adhesion to endothelium via LW-αvβ3 and CD44-CD44 interactions.
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Heroin neuroteratogenicity: targeting adenylyl cyclase as an underlying biochemical mechanism.
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How Gsalpha activates adenylyl cyclase.
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Identification of the endophilins (SH3p4/p8/p13) as novel binding partners for the beta1-adrenergic receptor.
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Inhibition of spontaneous beta 2-adrenergic activation rescues beta 1-adrenergic contractile response in cardiomyocytes overexpressing beta 2-adrenoceptor.
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Jaffe-Campanacci syndrome, revisited: detailed clinical and molecular analyses determine whether patients have neurofibromatosis type 1, coincidental manifestations, or a distinct disorder.
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Neutrophil beta(2)-adrenoceptor function in major depression: G(s) coupling, effects of imipramine and relationship to treatment outcome.
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Neutrophil beta2-adrenergic receptor coupling efficiency to Gs protein in subjects with post-traumatic stress disorder and normal controls.
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Ontogeny of regulatory mechanisms for beta-adrenoceptor control of rat cardiac adenylyl cyclase: targeting of G-proteins and the cyclase catalytic subunit.
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PKA-mediated phosphorylation of the beta1-adrenergic receptor promotes Gs/Gi switching.
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Protein kinase A-mediated phosphorylation of the beta 2-adrenergic receptor regulates its coupling to Gs and Gi. Demonstration in a reconstituted system.
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Recurrent GNAS mutations define an unexpected pathway for pancreatic cyst development.
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Signaling pathways mediating beta3-adrenergic receptor-induced production of interleukin-6 in adipocytes.
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Switching of the coupling of the beta2-adrenergic receptor to different G proteins by protein kinase A.
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Systematic errors in detecting biased agonism: Analysis of current methods and development of a new model-free approach.
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The oncocytic subtype is genetically distinct from other pancreatic intraductal papillary mucinous neoplasm subtypes.
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Thyroid carcinoma in the McCune-Albright syndrome: contributory role of activating Gs alpha mutations.
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Utility of DNA Profiling From Main Pancreatic Duct Fluid by Endoscopic Ultrasound and Endoscopic Retrograde Cholangiopancreatography to Screen for Malignant Potential.