1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
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Subject Areas on Research
- Activation of messenger-independent protein kinases in wild-type and phorbol ester-resistant EL4 thymoma cells.
- Activation of protein kinase C inhibits human keratinocyte migration.
- Acto-myosin drug effects and aqueous outflow function.
- Aluminum-induced DNA synthesis in osteoblasts: mediation by a G-protein coupled cation sensing mechanism.
- Concurrent exposure to heat shock and H7 synergizes to trigger breast cancer cell apoptosis while sparing normal cells.
- Corneal Endothelial Cell Migration and Proliferation Enhanced by Rho Kinase (ROCK) Inhibitors in In Vitro and In Vivo Models.
- Endogenous protein kinase-C activation in osteoblast-like cells modulates responsiveness to estrogen and estrogen receptor levels.
- Exceptional aggressiveness of cerebral cavernous malformation disease associated with PDCD10 mutations.
- Fasudil decreases lesion burden in a murine model of cerebral cavernous malformation disease.
- Forskolin stimulation of water and cation permeability in aquaporin 1 water channels.
- Identification, partial purification, and characterization of a novel phospholipid-dependent and fatty acid-activated protein kinase from human platelets.
- Influence of actin cytoskeletal integrity on matrix metalloproteinase-2 activation in cultured human trabecular meshwork cells.
- Interleukin-1beta inhibits gamma-aminobutyric acid type A (GABA(A)) receptor current in cultured hippocampal neurons.
- Microtubule disruption leads to cellular contraction in human trabecular meshwork cells.
- Phorbol ester inhibits granulocyte-macrophage colony-stimulating factor binding and tyrosine phosphorylation.
- Regulation of cholecystokinin secretion by calcium-dependent calmodulin kinase II: differential effects of phenylalanine and cAMP.
- Regulation of myosin light chain phosphorylation in the trabecular meshwork: role in aqueous humour outflow facility.
- RhoA Kinase Inhibition With Fasudil Versus Simvastatin in Murine Models of Cerebral Cavernous Malformations.
- Synthetic peptide corresponding to a conserved domain of the retroviral protein p15E blocks IL-1-mediated signal transduction.
- T cell activation up-regulates the expression of the focal adhesion kinase Pyk2: opposing roles for the activation of protein kinase C and the increase in intracellular Ca2+.
- Wound contraction is attenuated by fasudil inhibition of Rho-associated kinase.