omega-N-Methylarginine

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  Subject Areas on Research

  • Ca(2+)-dependent nitric oxide release in endothelial but not R3230Ac rat mammary adenocarcinoma cells. 
  • Effect of a NOS inhibitor, L-NMMA, on the contractile function of reperfused skeletal muscle. 
  • Effect of nitric oxide synthase inhibition on haemodynamics and outcome of patients with persistent cardiogenic shock complicating acute myocardial infarction: a phase II dose-ranging study. 
  • Flow cytometric analysis of nitric oxide production in human neutrophils using dichlorofluorescein diacetate in the presence of a calmodulin inhibitor. 
  • Host response to infection: the role of CpG DNA in induction of cyclooxygenase 2 and nitric oxide synthase 2 in murine macrophages. 
  • Hypersecretion of mucin in response to inflammatory mediators by guinea pig tracheal epithelial cells in vitro is blocked by inhibition of nitric oxide synthase. 
  • Hypoxia inhibits nitric oxide synthesis in isolated rabbit lung. 
  • Imbalance between xanthine oxidase and nitric oxide synthase signaling pathways underlies mechanoenergetic uncoupling in the failing heart. 
  • Induction of superoxide anion and nitric oxide production in cultured microglia. 
  • Interleukin-1, tumor necrosis factor alpha, and interleukin-17 synergistically up-regulate nitric oxide and prostaglandin E2 production in explants of human osteoarthritic knee menisci. 
  • Modulation of glutamate and aspartate release from slices of hippocampal area CA1 by inhibitors of arachidonic acid metabolism. 
  • Nitric oxide contributes to cerebrovascular shear-mediated dilatation but not steady-state cerebrovascular reactivity to carbon dioxide. 
  • Nitric oxide decreases oxidant-mediated hepatocyte injury. 
  • Nitric oxide is fundamental to neurovascular coupling in humans. 
  • Nitric oxide modulates branching morphogenesis in fetal rat lung explants. 
  • Nitric oxide synthase inhibition irreversibly decreases perfusion in the R3230Ac rat mammary adenocarcinoma. 
  • Oxidant stress stimulates mucin secretion and PLC in airway epithelium via a nitric oxide-dependent mechanism. 
  • Peroxynitrite formation and decreased catalase activity in autoimmune MRL-lpr/lpr mice. 
  • Polyribonucleotides induce nitric oxide production by human monocyte-derived macrophages. 
  • Regulation of nitric oxide synthesis by oxygen in vascular endothelial cells. 
  • Relative contribution of preload and afterload to the reduction in cardiac output caused by nitric oxide synthase inhibition with L-N(G)-methylarginine hydrochloride 546C88. 
  • Role of nitric oxide in vasodilation in upstream muscle during intermittent pneumatic compression. 
  • Stable expression of manganese superoxide dismutase (MnSOD) in insulinoma cells prevents IL-1beta- induced cytotoxicity and reduces nitric oxide production. 
  • The in vitro reversal of histamine-induced vasodilation in the human internal mammary artery. 
  • The role of nitric oxide in the pathogenesis of spontaneous murine autoimmune disease: increased nitric oxide production and nitric oxide synthase expression in MRL-lpr/lpr mice, and reduction of spontaneous glomerulonephritis and arthritis by orally administered NG-monomethyl-L-arginine. 
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  Keywords of People

  • Alexander, John Hunter Peel, Professor of Medicine, Medicine, Cardiology