beta-Naphthoflavone

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  Subject Areas on Research

  • Acetaminophen toxicity in cultured trout liver cells. II. Maintenance of cytochrome P450 1A1. 
  • Aminoanthracene is a mechanism-based inactivator of CYP1A in channel catfish hepatic tissue. 
  • Antioxidant responses and NRF2 in synergistic developmental toxicity of PAHs in zebrafish. 
  • Brevetoxin-6 (PbTx-6), a nonaromatic marine neurotoxin, is a ligand of the aryl hydrocarbon receptor. 
  • Comparative in vitro and in vivo benzo[a]pyrene-DNA adduct formation and its relationship to CYP1A activity in two species of ictalurid catfish. 
  • Cytochrome P-450- and glutathione-associated enzyme activities in freshly isolated enriched lung cell fractions from beta-naphthoflavone-treated male F344 rats. 
  • Cytochrome P4501A (CYP1A) in killifish (Fundulus heteroclitus): heritability of altered expression and relationship to survival in contaminated sediments. 
  • Cytochrome P450IA1 induction and localization in endothelium of vertebrate (teleost) heart. 
  • Development of the morpholino gene knockdown technique in Fundulus heteroclitus: a tool for studying molecular mechanisms in an established environmental model. 
  • Effects of inhibition and induction of cytochrome P-450 isozymes on hyperoxic lung injury in rats. 
  • Ethanol-inducible microsomal aniline hydroxylase activity and cytochrome P-450 isozymes in adult hen liver. 
  • Genomic and physiological responses to strong selective pressure during late organogenesis: few gene expression changes found despite striking morphological differences. 
  • In vivo modulation of 17 beta-estradiol-induced vitellogenin synthesis and estrogen receptor in rainbow trout (Oncorhynchus mykiss) liver cells by beta-naphthoflavone. 
  • Induction of hepatic CYP1A in channel catfish increases binding of 2-aminoanthracene to DNA in vitro and in vivo. 
  • Purification and characterization of cytochrome P450 isozymes from beta-naphthoflavone-induced adult hen liver. 
  • Screening of 16 common therapeutic drugs. Possible association with the Ah locus. 
  • Synergistic induction of AHR regulated genes in developmental toxicity from co-exposure to two model PAHs in zebrafish. 
  • The role of the aryl hydrocarbon receptor pathway in mediating synergistic developmental toxicity of polycyclic aromatic hydrocarbons to zebrafish.