Endothelin-1
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Subject Areas on Research
- Analysis of TRPV channel activation by stimulation of FCεRI and MRGPR receptors in mouse peritoneal mast cells.
- Analysis of responses to big endothelin in the hindquarters vascular bed of the cat.
- Association of the PHACTR1/EDN1 Genetic Locus With Spontaneous Coronary Artery Dissection.
- Biomarker changes during acute heart failure treatment.
- Bolus magnesium infusion in humans is associated with predominantly unfavourable changes in platelet aggregation and certain haemostatic factors.
- Caveolin 1 and G-Protein-Coupled Receptor Kinase-2 Coregulate Endothelial Nitric Oxide Synthase Activity in Sinusoidal Endothelial Cells.
- Circulating markers of inflammation and endothelial function, and their relationship to diabetic retinopathy.
- Comparison of relaxation responses to multiple vasodilators in TxA(2)-analog and endothelin-1-precontracted pulmonary arteries.
- Concentration-related effects of nitric oxide and endothelin-1 on human trabecular meshwork cell contractility.
- Could coenzyme Q10 affect hemostasis by inhibiting platelet vitronectin (CD51/CD61) receptor?
- ETAR and protein kinase A pathway mediate ET-1 sensitization of TRPA1 channel: A molecular mechanism of ET-1-induced mechanical hyperalgesia.
- Effect of a dominant negative ras on myocardial hypertrophy by using adenoviral-mediated gene transfer.
- Effect of lidocaine on endothelin-1-mediated airway smooth muscle contraction in the rat trachea.
- Effect of low versus high dialysate sodium concentration on blood pressure and endothelial-derived vasoregulators during hemodialysis: a randomized crossover study.
- Effects of intracoronary diltiazem on certain hemostatic parameters during acute myocardial infarction in swine.
- Endothelin-1 activates endothelial cell nitric-oxide synthase via heterotrimeric G-protein betagamma subunit signaling to protein jinase B/Akt.
- Endothelin-1 blockade corrects mesenteric hypoperfusion in a porcine low cardiac output model.
- Epidermal growth factor receptor trans-activation mediates the tonic and fibrogenic effects of endothelin in the aortic wall of transgenic mice.
- Extracellular signal-regulated kinase plays an essential role in hypertrophic agonists, endothelin-1 and phenylephrine-induced cardiomyocyte hypertrophy.
- Feasibility of vitrification as a storage method for tissue-engineered blood vessels.
- G protein- and β-arrestin Signaling Profiles of Endothelin Derivatives at the Type A Endothelin Receptor.
- Hemostatic changes after dietary coenzyme Q10 supplementation in swine.
- Hemostatic changes after early versus late intracoronary magnesium during acute myocardial infarction in swine.
- Heparin binding EGF is necessary for vasospastic response to endothelin.
- Increased blood pressure in mice lacking cytochrome P450 2J5.
- Increased mortality with elevated plasma endothelin-1 in acute heart failure: an ASCEND-HF biomarker substudy.
- Intracoronary magnesium and diltiazem affect to a similar extent certain hemostatic factors during acute myocardial infarction in swine.
- Mac-1 inhibitor affects certain hemostatic parameters during myocardial stunning in swine.
- Mutational analysis of endothelin receptor b1 (rose) during neural crest and pigment pattern development in the zebrafish Danio rerio.
- Myogenic constriction of human coronary arterioles.
- Pharmacological regulation of outflow resistance distal to Schlemm's canal.
- Phase 3, randomized, placebo-controlled study of zibotentan (ZD4054) in patients with castration-resistant prostate cancer metastatic to bone.
- Phosphorylation and desensitization of human endothelin A and B receptors. Evidence for G protein-coupled receptor kinase specificity.
- Placenta growth factor in sickle cell disease: association with hemolysis and inflammation.
- Probing the mechanisms of intradialytic hypertension: a pilot study targeting endothelial cell dysfunction.
- Pulmonary vasoconstriction by serotonin is inhibited by S-nitrosoglutathione.
- Regulation of cardiac nitric oxide signaling by nuclear β-adrenergic and endothelin receptors.
- Regulation of myosin light chain phosphorylation in the trabecular meshwork: role in aqueous humour outflow facility.
- Sensitization to Acute Procedural Pain in Pediatric Sickle Cell Disease: Modulation by Painful Vaso-occlusive Episodes, Age, and Endothelin-1
- Serial changes of soluble endothelin-1 levels during myocardial ischaemia-reperfusion. Effects of magnesium, diltiazem and a novel MAC-1 inhibitor.
- Tezosentan in patients with acute heart failure and acute coronary syndromes: design of the fourth Randomized Intravenous Tezosentan Study (RITZ-4).
- Tezosentan normalizes hepatomesenteric perfusion in a porcine model of cardiac tamponade.
- The kidney and hypertension: novel insights from transgenic models.
- Transient Receptor Potential Vanilloid 4 Ion Channel Functions as a Pruriceptor in Epidermal Keratinocytes to Evoke Histaminergic Itch.
- Treatment-related biomarkers in pulmonary hypertension patients on oral therapies.
- Treatment-related biomarkers in pulmonary hypertension.
- UVB radiation generates sunburn pain and affects skin by activating epidermal TRPV4 ion channels and triggering endothelin-1 signaling.
- Vasodilators in the treatment of acute heart failure: what we know, what we don't.
- beta -Arrestin-mediated recruitment of the Src family kinase Yes mediates endothelin-1-stimulated glucose transport.
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Keywords of People
- Jokerst, Nan Marie, J. A. Jones Distinguished Professor of Electrical and Computer Engineering, Nicholas Institute-Energy Initiative
- O'Connor, Christopher Michael, Adjunct Professor in the Department of Medicine, Medicine, Clinical Pharmacology