Genes, MDR

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  Subject Areas on Research

  • ABCB1/MDR1 gene determines susceptibility and phenotype in ulcerative colitis: discrimination of critical variants using a gene-wide haplotype tagging approach. 
  • Ascites Increases Expression/Function of Multidrug Resistance Proteins in Ovarian Cancer Cells. 
  • Association of multi-drug resistance gene polymorphisms with pancreatic cancer outcome. 
  • Association of multidrug resistance in epilepsy with a polymorphism in the drug-transporter gene ABCB1. 
  • Functional consequences of substitution mutations in MepR, a repressor of the Staphylococcus aureus MepA multidrug efflux pump gene. 
  • Hypoxia-inducible factor-1-dependent regulation of the multidrug resistance (MDR1) gene. 
  • Interaction of pyridostigmine bromide and N,N-diethyl-m-toluamide alone and in combination with P-glycoprotein expressed in Escherichia coli leaky mutant. 
  • Pharmacogenetics of nevirapine-associated hepatotoxicity: an Adult AIDS Clinical Trials Group collaboration. 
  • Reversal of P-glycoprotein expressed in Escherichia coli leaky mutant by ascorbic acid. 
  • Substantial multiclass transmitted drug resistance and drug-relevant polymorphisms among treatment-naïve behaviorally HIV-infected youth. 
  • The farnesyl protein transferase inhibitor SCH66336 is a potent inhibitor of MDR1 product P-glycoprotein.