Halobacterium salinarum

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  Subject Areas on Research

  • A predictive model for transcriptional control of physiology in a free living cell. 
  • A single transcription factor regulates evolutionarily diverse but functionally linked metabolic pathways in response to nutrient availability. 
  • A transcription factor links growth rate and metabolism in the hypersaline adapted archaeon Halobacterium salinarum. 
  • A transcription network of interlocking positive feedback loops maintains intracellular iron balance in archaea. 
  • Agl28 and Agl29 are key components of a Halobacterium salinarum N-glycosylation pathway. 
  • An N-linked tetrasaccharide from Halobacterium salinarum presents a novel modification, sulfation of iduronic acid at the O-3 position. 
  • An archaeal histone-like protein regulates gene expression in response to salt stress. 
  • Archaeal cells share common size control with bacteria despite noisier growth and division. 
  • Copy number variation is associated with gene expression change in archaea. 
  • Detecting differential growth of microbial populations with Gaussian process regression. 
  • Dynamic Metabolite Profiling in an Archaeon Connects Transcriptional Regulation to Metabolic Consequences. 
  • Global Transcriptional Programs in Archaea Share Features with the Eukaryotic Environmental Stress Response. 
  • Glyco-engineering in Archaea: differential N-glycosylation of the S-layer glycoprotein in a transformed Haloferax volcanii strain. 
  • Growth-Phase-Specific Modulation of Cell Morphology and Gene Expression by an Archaeal Histone Protein. 
  • Halobacterium salinarum NRC-1 PeptideAtlas: toward strategies for targeted proteomics and improved proteome coverage. 
  • Noninvasive optical inhibition with a red-shifted microbial rhodopsin. 
  • Prevalence of transcription promoters within archaeal operons and coding sequences. 
  • Protein-DNA binding dynamics predict transcriptional response to nutrients in archaea. 
  • Revisiting N-glycosylation in Halobacterium salinarum: Characterizing a dolichol phosphate- and glycoprotein-bound tetrasaccharide. 
  • Substrate promiscuity: AglB, the archaeal oligosaccharyltransferase, can process a variety of lipid-linked glycans. 
  • Systems biology approaches to defining transcription regulatory networks in halophilic archaea. 
  • The Firegoose: two-way integration of diverse data from different bioinformatics web resources with desktop applications. 
  • The RosR transcription factor is required for gene expression dynamics in response to extreme oxidative stress in a hypersaline-adapted archaeon. 
  • The anatomy of microbial cell state transitions in response to oxygen. 
  • Two transcription factors are necessary for iron homeostasis in a salt-dwelling archaeon. 
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  Keywords of People

  • Schmid, Amy K., David M. Goodner Associate Professor, Duke Science & Society