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Subject Areas on Research
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A B-cell-homing chemokine made in lymphoid follicles activates Burkitt's lymphoma receptor-1.
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A role for fractalkine and its receptor (CX3CR1) in cardiac allograft rejection.
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Activation of the 9E3/cCAF chemokine by phorbol esters occurs via multiple signal transduction pathways that converge to MEK1/ERK2 and activate the Elk1 transcription factor.
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Acute ethanol administration downregulates human immunodeficiency virus-1 glycoprotein 120-induced KC and RANTES production by murine Kupffer cells and splenocytes.
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Alpha-chemokine receptor blockade reduces high mobility group box 1 protein-induced lung inflammation and injury and improves survival in sepsis.
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Anti-angiogenic effects of interleukin-12 delivered by a novel hyperthermia induced gene construct.
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Anti-neutrophil chemokine preserves alveolar development in hyperoxia-exposed newborn rats.
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CD8 positive T cells influence antigen-specific immune responses through the expression of chemokines.
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CXCR4 enhances adhesion of B16 tumor cells to endothelial cells in vitro and in vivo via beta(1) integrin.
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Chemokines and B-cell homing to follicles.
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Chemokines and their receptors in human renal allotransplantation.
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Chronic ethanol intoxication enhances the production of cytokine-induced neutrophil chemoattractant and macrophage inflammatory protein-2 by hepatocytes after human immunodeficiency virus-1 glycoprotein 120 vaccination.
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ELR+ CXC chemokines and oncogenic Ras-mediated tumorigenesis.
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Effects of flow and diffusion on chemotaxis studies in a microfabricated gradient generator.
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Effects of oxidized LDL on mononuclear phagocytes: inhibition of induction of four inflammatory cytokine gene RNAs, release of NO, and cytolysis of tumor cells.
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Efficacy of systemic administration of SDF-1 in a model of vascular insufficiency: support for an endothelium-dependent mechanism.
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Elevation of CXCR3-binding chemokines in urine indicates acute renal-allograft dysfunction.
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Expression analysis of the T-cell-targeting chemokines CXCL9 and CXCL10 in mice and humans with endothelial infections caused by rickettsiae of the spotted fever group.
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Expression of CXC chemokine receptor-4 enhances the pulmonary metastatic potential of murine B16 melanoma cells.
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Expression of three forms of melanoma growth stimulating activity (MGSA)/gro in human retinal pigment epithelial cells.
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Fractalkine and CX3CR1 mediate a novel mechanism of leukocyte capture, firm adhesion, and activation under physiologic flow.
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Gene expression profiling of familial and sporadic interstitial pneumonia.
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Genetic influence of CCR5, CCR2, and SDF1 variants on human immunodeficiency virus 1 (HIV-1)-related disease progression and neurological impairment, in children with symptomatic HIV-1 infection.
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HIV envelope gp120 activates human arterial smooth muscle cells.
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High throughput, cell type-specific analysis of key proteins in human endometrial biopsies of women from fertile and infertile couples.
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How do chemokines navigate neutrophils to the target site: Dissecting the structural mechanisms and signaling pathways.
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Increased transmigration of G-CSF-mobilized peripheral blood CD34+ cells after overnight storage at 37 degrees C.
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Inflammation and the reciprocal production of granulocytes and lymphocytes in bone marrow.
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Inflammation controls B lymphopoiesis by regulating chemokine CXCL12 expression.
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Lymphotoxin alpha/beta and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleen.
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MGSA/GRO transcription is differentially regulated in normal retinal pigment epithelial and melanoma cells.
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Oncogenic and metastatic properties of preprotachykinin-I and neurokinin-1 genes.
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Preventing stem cell incorporation into choroidal neovascularization by targeting homing and attachment factors.
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Redirecting migration of T cells to chemokine secreted from tumors by genetic modification with CXCR2.
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Regulation of human chemokine receptors CXCR4. Role of phosphorylation in desensitization and internalization.
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Repair-related activation of hedgehog signaling promotes cholangiocyte chemokine production.
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Role of hypoxia in inflammatory upper airway disease.
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Selective expression of stromal-derived factor-1 in the capillary vascular endothelium plays a role in Kaposi sarcoma pathogenesis.
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Shear flow-dependent integration of apical and subendothelial chemokines in T-cell transmigration: implications for locomotion and the multistep paradigm.
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Should we B-leavin' now?
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Soluble ICAM-1, MCP-1, and MIP-2 protein secretion by rat pleural mesothelial cells following exposure to amosite asbestos.
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Suppression of NF-kappaB-dependent proinflammatory gene expression in human RPE cells by a proteasome inhibitor.
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Surveillance of acute rejection in baboon renal transplantation by elevation of interferon-gamma inducible protein-10 and monokine induced by interferon-gamma in urine.
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The BCR/ABL oncogene alters the chemotactic response to stromal-derived factor-1alpha.
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The CC chemokine thymus-derived chemotactic agent 4 (TCA-4, secondary lymphoid tissue chemokine, 6Ckine, exodus-2) triggers lymphocyte function-associated antigen 1-mediated arrest of rolling T lymphocytes in peripheral lymph node high endothelial venules.
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The CXC chemokine cCAF stimulates precocious deposition of ECM molecules by wound fibroblasts, accelerating development of granulation tissue.
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The N- and C-terminal peptides of hIL8/CXCL8 are ligands for hCXCR1 and hCXCR2.
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The spontaneously hypertensive rat: an experimental model of sulfur dioxide-induced airways disease.
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Ultrastructure and function of the fractalkine mucin domain in CX(3)C chemokine domain presentation.
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Vascular endothelial growth factor promotes breast carcinoma invasion in an autocrine manner by regulating the chemokine receptor CXCR4.
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Keywords of People
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Choi, Steven Sok,
Associate Professor of Medicine,
Medicine, Gastroenterology
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Erickson, Harold Paul,
James B. Duke Distinguished Professor of Cell Biology,
Cell Biology
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Gunn, Michael Dee,
Professor of Medicine,
Immunology