Aldose-Ketose Isomerases

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  Subject Areas on Research

  • An investigation of the equilibria between aqueous ribose, ribulose, and arabinose. 
  • Cloning the Cryptococcus neoformans TRP1 gene by complementation in Saccharomyces cerevisiae. 
  • Concerted proton transfer mechanism of Clostridium thermocellum ribose-5-phosphate isomerase. 
  • High-throughput screen for inhibitors of 1-deoxy-d-xylulose 5-phosphate reductoisomerase by surrogate ligand competition. 
  • Metabolite gene regulation: imidazole and imidazole derivatives which circumvent cyclic adenosine 3',5'-monophosphate in induction of the Escherichia coli L-arabinose operon.