Chondroitin ABC Lyase

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  Subject Areas on Research

  • A simple technique for augmentation of axonal ingrowth into chondroitinase-treated acellular nerve grafts using nerve growth factor. 
  • Axonal regrowth after spinal cord injury via chondroitinase and the tissue plasminogen activator (tPA)/plasmin system. 
  • Dorsal root ganglia neurite extension is inhibited by mechanical and chondroitin sulfate-rich interfaces. 
  • Sustained delivery of thermostabilized chABC enhances axonal sprouting and functional recovery after spinal cord injury. 
  • Therapeutic efficacy of microtube-embedded chondroitinase ABC in a canine clinical model of spinal cord injury.