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Subject Areas on Research
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A colorimetric gold nanoparticle sensor to interrogate biomolecular interactions in real time on a surface.
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Astatine-211-labeled biotin conjugates resistant to biotinidase for use in pretargeted radioimmunotherapy.
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Binding and signaling of surface-immobilized reagentless fluorescent biosensors derived from periplasmic binding proteins.
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Complications in cell-surface labelling by biotinylation of Candida albicans due to avidin conjugate binding to cell-wall proteins.
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Control of protein-ligand recognition using a stimuli-responsive polymer.
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Cutting edge: C3d functions as a molecular adjuvant in the absence of CD21/35 expression.
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DNA-templated self-assembly of protein and nanoparticle linear arrays.
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DNA-templated self-assembly of protein arrays and highly conductive nanowires.
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Detection of epitope-tagged proteins in flow cytometry: fluorescence resonance energy transfer-based assays on beads with femtomole resolution.
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Differential osteopontin expression in phenotypically distinct subclones of murine breast cancer cells mediates metastatic behavior.
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Direct force measurements of the streptavidin-biotin interaction.
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Direct observation of multimer stabilization in the mechanical unfolding pathway of a protein undergoing oligomerization.
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Distinct MutS DNA-binding modes that are differentially modulated by ATP binding and hydrolysis.
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Dual-order snapshot spectral imaging of plasmonic nanoparticles.
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Dynamic seeding of perfusing human umbilical vein endothelial cells (HUVECs) onto dual-function cell adhesion ligands: Arg-Gly-Asp (RGD)-streptavidin and biotinylated fibronectin.
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Effect of streptavidin RGD mutant on the adhesion of endothelial cells.
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Effect of streptavidin affinity mutants on the integrin-independent adhesion of biotinylated endothelial cells.
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Effect of streptavidin-biotin on endothelial vasoregulation and leukocyte adhesion.
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Elastomeric microparticles for acoustic mediated bioseparations.
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Electrochemical biosensor of nanocube-augmented carbon nanotube networks.
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Engineered chimeric streptavidin tetramers as novel tools for bioseparations and drug delivery.
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Enhanced TOF-SIMS imaging of a micropatterned protein by stable isotope protein labeling.
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Founder's Award, Society for Biomaterials. Sixth World Biomaterials Congress 2000, Kamuela, HI,May 15-20, 2000. Really smart bioconjugates of smart polymers and receptor proteins.
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Helical crystallization on lipid nanotubes: streptavidin as a model protein.
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High-affinity augmentation of endothelial cell attachment: long-term effects on focal contact and actin filament formation.
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High-throughput screen for inhibitors of 1-deoxy-d-xylulose 5-phosphate reductoisomerase by surrogate ligand competition.
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Label-free plasmonic detection of biomolecular binding by a single gold nanorod.
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Molecular engineering of proteins and polymers for targeting and intracellular delivery of therapeutics.
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Nanomechanics of streptavidin hubs for molecular materials.
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Peptides, antibodies, and FRET on beads in flow cytometry: A model system using fluoresceinated and biotinylated beta-endorphin.
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Plasmonic detection of a model analyte in serum by a gold nanorod sensor.
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Preparation and characterization of anti-tenascin monoclonal antibody-streptavidin conjugates for pretargeting applications.
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Rational selection of gold nanorod geometry for label-free plasmonic biosensors.
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Site-directed mutagenesis studies of the high-affinity streptavidin-biotin complex: contributions of tryptophan residues 79, 108, and 120.
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Small-volume rapid-mix device for subsecond kinetic analysis in flow cytometry.
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Spectroscopic characterization of streptavidin functionalized quantum dots.
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Streptavidin binding and endothelial cell adhesion to biotinylated fibronectin.
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Streptavidin-biotin binding energetics.
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Structural studies of binding site tryptophan mutants in the high-affinity streptavidin-biotin complex.
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Synergistic effect of shear stress and streptavidin-biotin on the expression of endothelial vasodilator and cytoskeleton genes.
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Synthesis and preliminary biological evaluation of (3-iodobenzoyl)norbiotinamide and ((5-iodo-3-pyridinyl)carbonyl)norbiotinamide: two radioiodinated biotin conjugates with improved stability.
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The development of quantum dot calibration beads and quantitative multicolor bioassays in flow cytometry and microscopy.
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The motion of a single molecule, the lambda-receptor, in the bacterial outer membrane.
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The relationship between ligand-binding thermodynamics and protein-ligand interaction forces measured by atomic force microscopy.
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Three-step radioimmunotherapy with yttrium-90 biotin: dosimetry and pharmacokinetics in cancer patients.
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Two-dimensional protein crystallization via metal-ion coordination by naturally occurring surface histidines.
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X-ray crystallographic studies of streptavidin mutants binding to biotin.
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Keywords of People