Archaeal Proteins

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  Subject Areas on Research

  • A predicted geranylgeranyl reductase reduces the ω-position isoprene of dolichol phosphate in the halophilic archaeon, Haloferax volcanii. 
  • A predictive model for transcriptional control of physiology in a free living cell. 
  • A single transcription factor regulates evolutionarily diverse but functionally linked metabolic pathways in response to nutrient availability. 
  • A transcription factor links growth rate and metabolism in the hypersaline adapted archaeon Halobacterium salinarum. 
  • A transcription network of interlocking positive feedback loops maintains intracellular iron balance in archaea. 
  • Agl28 and Agl29 are key components of a Halobacterium salinarum N-glycosylation pathway. 
  • AglJ adds the first sugar of the N-linked pentasaccharide decorating the Haloferax volcanii S-layer glycoprotein. 
  • AglQ is a novel component of the Haloferax volcanii N-glycosylation pathway. 
  • AglR is required for addition of the final mannose residue of the N-linked glycan decorating the Haloferax volcanii S-layer glycoprotein. 
  • An archaeal histone-like protein regulates gene expression in response to salt stress. 
  • Assembling Glycan-Charged Dolichol Phosphates: Chemoenzymatic Synthesis of a Haloferax volcanii N-Glycosylation Pathway Intermediate. 
  • Cell division without FtsZ--a variety of redundant mechanisms. 
  • Crystal structure of a pol alpha family DNA polymerase from the hyperthermophilic archaeon Thermococcus sp. 9 degrees N-7. 
  • Different routes to the same ending: comparing the N-glycosylation processes of Haloferax volcanii and Haloarcula marismortui, two halophilic archaea from the Dead Sea. 
  • Distinct Regions of the Haloferax volcanii Dolichol Phosphate-Mannose Synthase AglD Mediate the Assembly and Subsequent Processing of the Lipid-Linked Mannose. 
  • Domain Organization in the 54-kDa Subunit of the Chloroplast Signal Recognition Particle. 
  • Dynamic Metabolite Profiling in an Archaeon Connects Transcriptional Regulation to Metabolic Consequences. 
  • Expression in Escherichia coli of the thermostable DNA polymerase from Pyrococcus furiosus. 
  • Functional advantages conferred by extracellular prokaryotic membrane vesicles. 
  • GlpR Is a Direct Transcriptional Repressor of Fructose Metabolic Genes in Haloferax volcanii. 
  • Halobacterium salinarum NRC-1 PeptideAtlas: toward strategies for targeted proteomics and improved proteome coverage. 
  • Lipid modification gives rise to two distinct Haloferax volcanii S-layer glycoprotein populations. 
  • N-glycosylation in the thermoacidophilic archaeon Sulfolobus acidocaldarius involves a short dolichol pyrophosphate carrier. 
  • Protein glycosylation as an adaptive response in Archaea: growth at different salt concentrations leads to alterations in Haloferax volcanii S-layer glycoprotein N-glycosylation. 
  • Protein-DNA binding dynamics predict transcriptional response to nutrients in archaea. 
  • Structure of the hypothetical protein PF0899 from Pyrococcus furiosus at 1.85 A resolution. 
  • Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages. 
  • Substrate promiscuity: AglB, the archaeal oligosaccharyltransferase, can process a variety of lipid-linked glycans. 
  • The Hypersaline Archaeal Histones HpyA and HstA Are DNA Binding Proteins That Defy Categorization According to Commonly Used Functional Criteria. 
  • The Ribbon-Helix-Helix Domain Protein CdrS Regulates the Tubulin Homolog ftsZ2 To Control Cell Division in Archaea. 
  • The RosR transcription factor is required for gene expression dynamics in response to extreme oxidative stress in a hypersaline-adapted archaeon. 
  • The anatomy of microbial cell state transitions in response to oxygen. 
  • The structure of formylmethanofuran: tetrahydromethanopterin formyltransferase in complex with its coenzymes. 
  • Transcriptional Regulation in Archaea: From Individual Genes to Global Regulatory Networks. 
  • TrmB Family Transcription Factor as a Thiol-Based Regulator of Oxidative Stress Response. 
  • Two transcription factors are necessary for iron homeostasis in a salt-dwelling archaeon. 
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  Keywords of People

  • Erickson, Harold Paul, James B. Duke Distinguished Professor Emeritus, Cell Biology
  • Schmid, Amy K., David M. Goodner Associate Professor, Duke Science & Society