Thrombophilia
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Subject Areas on Research
- A clinical cardiology perspective of thrombophilias.
- Adverse effects of corticosteroids on the cardiovascular system.
- Antibodies from patients with heparin-induced thrombocytopenia stimulate monocytic cells to express tissue factor and secrete interleukin-8.
- Anticoagulants in pregnancy.
- Antiplatelet therapy in pediatric cardiovascular patients.
- Atherothrombotic disorders: new insights from hematology.
- Characteristics of abdominal vein thrombosis in children and adults.
- Characterization of a murine monoclonal antibody that mimics heparin-induced thrombocytopenia antibodies.
- Characterization of the hypercoagulable state in patients with sickle cell disease.
- Clinical and laboratory evaluation of thrombophilia.
- Clinical causes and treatment of the thrombotic storm.
- Coagulation abnormalities in patients with hip osteonecrosis.
- Coagulation and fibrinolytic protein kinetics in cardiopulmonary bypass.
- Coagulation disorders and their cutaneous presentations: Pathophysiology.
- Coagulopathy of Coronavirus Disease 2019.
- Cost-effectiveness of testing for hypercoagulability and effects on treatment strategies in patients with deep vein thrombosis.
- Depression and cardiovascular disease: mechanisms of interaction.
- Diagnosis and management of sepsis-induced coagulopathy and disseminated intravascular coagulation.
- Diagnostic and Therapeutic Challenges.
- Do East Asians have different hypercoagulable states compared with Western population?
- Does Anticoagulation Improve Flap Outcomes in Hypercoagulable Patients? A Systematic Review.
- Dysregulation of hemostasis by cancer.
- Effects of inherited thrombophilic mutations in an adolescent with antiphospholipid syndrome and systemic lupus erythematosus.
- Elevated prothrombin results in clots with an altered fiber structure: a possible mechanism of the increased thrombotic risk.
- Etiology and assessment of hypercoagulability with lessons from heparin-induced thrombocytopenia.
- Evidence-Based Practical Guidance for the Antithrombotic Management in Patients With Coronavirus Disease (COVID-19) in 2020.
- Excess factor VIII and hypercoagulability.
- Heparin-induced thrombocytopenia: when a low platelet count is a mandate for anticoagulation.
- High altitude: a hypercoagulable state: results of a prospective cohort study.
- Hypercoagulability - The Underdiagnosed and Undertreated Nemesis of Congenital Heart Surgery.
- Hypercoagulability affecting early vein graft patency does not exist after off-pump coronary artery bypass.
- Hypercoagulability and coronavirus disease 2019-associated hypoxemic respiratory failure: Mechanisms and emerging management paradigms.
- Hypercoagulability, platelet function, inflammation and coronary artery disease acuity: results of the Thrombotic RIsk Progression (TRIP) study.
- Hypercoagulable states in cardiovascular disease.
- Hypercoagulable states: a review.
- Hypercoagulation and thrombophilia in liver disease.
- Infant cardiopulmonary bypass: a procoagulant state.
- Inherited thrombophilia in childhood arterial stroke: data from Lebanon.
- Management of cocaine-associated chest pain and myocardial infarction: a scientific statement from the American Heart Association Acute Cardiac Care Committee of the Council on Clinical Cardiology.
- On-Treatment Outcomes in Patients With Worsening Renal Function With Rivaroxaban Compared With Warfarin: Insights From ROCKET AF.
- Pathophysiological Response to Trauma-Induced Coagulopathy: A Comprehensive Review.
- Perioperative Management of the Gynecologic Patient on Long-term Anticoagulation.
- Potential thrombophilic mutations/polymorphisms in patients with no flow-limiting stenosis after myocardial infarction.
- Pregnancy-associated thrombosis.
- Prenatal screening for thrombophilia: the background and the approach.
- Prevention and treatment of venous thromboembolism in pregnancy.
- Prevention of venous thromboembolism in pregnancy: a review of guidelines, 2000-2011.
- Pro32Pro33 mutations in the integrin β3 PSI domain result in αIIbβ3 priming and enhanced adhesion: reversal of the hypercoagulability phenotype by the Src inhibitor SKI-606.
- Regulatable aptamers in medicine: focus on antithrombotic strategies.
- Role of thrombotic and fibrinolytic alterations in the pathogenesis and treatment of osteonecrosis.
- SARS-CoV-2 and Stroke in a New York Healthcare System.
- Scientific and Standardization Committee communication: Clinical guidance on the diagnosis, prevention, and treatment of venous thromboembolism in hospitalized patients with COVID-19.
- Screening for hypercoagulable syndromes following stroke.
- Sickle cell disease is associated with iron mediated hypercoagulability.
- Temporal trends in maternal medical conditions and stillbirth.
- The U.S. Thrombosis and Hemostasis Centers pilot sites program.
- The frequency of anticardiolipin antibodies and genetic mutations associated with hypercoagulability among patients with Wegener's granulomatosis with and without history of a thrombotic event.
- The scientific basis for evaluation and management of thrombotic disorders.
- The vulnerable endothelium: priming the vascular endothelium for thrombosis with unfractionated heparin: biologic plausibility for observations from the Superior Yield of the New Strategy of Enoxaparin, Revascularization and GlYcoprotein IIb/IIIa Inhibitors (SYNERGY) trial.
- Thromboembolism in pregnancy: recurrence risks, prevention and management.
- Thromboinflammation and the hypercoagulability of COVID-19.
- Thrombophilia screening in asymptomatic children.
- Thrombophilias and recurrent miscarriage.
- Thrombophilias: when should we test and how does it help?
- Thrombosis during pregnancy and the postpartum period.
- Thrombosis, thrombophilia, and thromboprophylaxis in pregnancy.
- Thrombotic preparedness in aging: a translatable construct for thrombophilias?
- Thrombotic storm revisited: preliminary diagnostic criteria suggested by the thrombotic storm study group.
- Tissue factor and fibrin in tumor angiogenesis.
- Why is depression bad for the failing heart? A review of the mechanistic relationship between depression and heart failure.
- [Hematologic diseases: from within the heart].
- [Recent advances in atherothrombotic diseases].
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Keywords of People
- O'Connor, Christopher Michael, Richard Sean Stack, M.D. Distinguished Professor, Medicine, Clinical Pharmacology
- Schanberg, Laura Eve, Professor of Pediatrics, Pediatrics, Rheumatology
- Shah, Nirmish Ramesh, Associate Professor of Medicine, School of Nursing