Autocrine Communication
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Subject Areas on Research
- Abi3bp is a multifunctional autocrine/paracrine factor that regulates mesenchymal stem cell biology.
- An FGF autocrine loop initiated in second heart field mesoderm regulates morphogenesis at the arterial pole of the heart.
- An heregulin-EGFR-HER3 autocrine signaling axis can mediate acquired lapatinib resistance in HER2+ breast cancer models.
- Autocrine BDNF-TrkB signalling within a single dendritic spine.
- Autocrine Complement Inhibits IL10-Dependent T-cell-Mediated Antitumor Immunity to Promote Tumor Progression.
- Autocrine Semaphorin3A stimulates eukaryotic initiation factor 4E-dependent RhoA translation in breast tumor cells.
- Autocrine phosphorylation of p70(S6k) in response to acute stretch in myotubes.
- Autocrine prolactin induced by the Pten-Akt pathway is required for lactation initiation and provides a direct link between the Akt and Stat5 pathways.
- Autocrine semaphorin3A stimulates alpha2 beta1 integrin expression/function in breast tumor cells.
- Autocrine signaling in carcinoma: VEGF and the alpha6beta4 integrin.
- Bladder fibrosis during outlet obstruction is triggered through the NLRP3 inflammasome and the production of IL-1β.
- Bone protection by inhibition of microRNA-182.
- Cross-talk between TGF-beta1 and IL-6 in human trabecular meshwork cells.
- Enforced expression of FGF-7 promotes epithelial hyperplasia whereas a dominant negative FGFR2iiib promotes the emergence of neuroendocrine phenotype in prostate glands of transgenic mice.
- Epithelial-mesenchymal interactions in the alteration of gene expression and morphology following lung injury.
- Estrogen-induced mitogenesis of MCF-7 cells does not require the induction of mitogen-activated protein kinase activity.
- Evidence that autocrine signaling through Bmpr1a regulates the proliferation, survival and morphogenetic behavior of distal lung epithelial cells.
- Hepatic fibrogenesis requires sympathetic neurotransmitters.
- IL-11 is a crucial determinant of cardiovascular fibrosis.
- IL-17 Production of Neutrophils Enhances Antibacteria Ability but Promotes Arthritis Development During Mycobacterium tuberculosis Infection.
- L-DOPA is an endogenous ligand for OA1.
- Mechanisms of disease progression in NASH: new paradigms.
- Neuroanatomical evidence for a putative autocrine/paracrine signaling system involving nicotinic acetylcholine receptors, purinergic receptors, and nitric oxide synthase in the airways.
- Neurotrophin-3 mediates the autocrine survival of the catecholaminergic CAD CNS neuronal cell line.
- Pheromones stimulate mating and differentiation via paracrine and autocrine signaling in Cryptococcus neoformans.
- Platelet biology for the clinician-scientist: an evolution of understanding.
- Regulatory Circuits and Bi-directional Signaling between Stem Cells and Their Progeny.
- Self-administering cannabinoids.
- Sonic hedgehog is an autocrine viability factor for myofibroblastic hepatic stellate cells.
- Stem cell factor and c-kit are expressed by and may affect vascular SMCs through an autocrine pathway.
- The estrogen receptor as a mediator of the pathological actions of cholesterol in breast cancer.
- The role of Hedgehog signaling in fibrogenic liver repair.
- Trefoil factor 1 acts to suppress senescence induced by oncogene activation during the cellular transformation process.
- WNT11 expression is induced by estrogen-related receptor alpha and beta-catenin and acts in an autocrine manner to increase cancer cell migration.
- Wnt/PCP controls spreading of Wnt/β-catenin signals by cytonemes in vertebrates.
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Keywords of People
- Choi, Steven Sok, Associate Professor of Medicine, Medicine, Gastroenterology
- Liton, Paloma Borrajo, Associate Professor in Ophthalmology, Pathology
- McDonnell, Donald Patrick, Chair, Department of Pharmacology & Cancer Biology, Duke Innovation & Entrepreneurship