GAP-43 Protein

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  Subject Areas on Research

  • A neural-specific GAP-43 core promoter located between unusual DNA elements that interact to regulate its activity. 
  • A new millenium for spinal cord regeneration: growth-associated genes. 
  • A protein induced during nerve growth (GAP-43) is a major component of growth-cone membranes. 
  • Activity-dependent expression of RNA binding protein HuD and its association with mRNAs in neurons. 
  • Axonal growth-associated proteins. 
  • Bone Marrow Mesenchymal Stem Cell Transplantation Increases GAP-43 Expression via ERK1/2 and PI3K/Akt Pathways in Intracerebral Hemorrhage. 
  • Changes in the distribution of GAP-43 during the development of neuronal polarity. 
  • Ciliary neurotrophic factor is an axogenesis factor for retinal ganglion cells. 
  • Development of neuronal polarity: GAP-43 distinguishes axonal from dendritic growth cones. 
  • Elevated synthesis of an axonally transported protein correlates with axon outgrowth in normal and injured pyramidal tracts. 
  • Fate of GAP-43 in ascending spinal axons of DRG neurons after peripheral nerve injury: delayed accumulation and correlation with regenerative potential. 
  • GAP-43 as a 'calmodulin sponge' and some implications for calcium signalling in axon terminals. 
  • GAP-43 promoter elements in transgenic zebrafish reveal a difference in signals for axon growth during CNS development and regeneration. 
  • Identification of a novel repressive element that contributes to neuron-specific gene expression. 
  • Immunohistochemistry of the canine vomeronasal organ. 
  • Immunohistochemistry of the canine vomeronasal organ. 
  • Injury-associated induction of GAP-43 expression displays axon branch specificity in rat dorsal root ganglion neurons. 
  • Mammalian target of rapamycin (mTOR) activation increases axonal growth capacity of injured peripheral nerves. 
  • Multiple elements may be used for regulation of the GAP-43 gene in different cell-types. 
  • Neural selective activation and temporal regulation of a mammalian GAP-43 promoter in zebrafish. 
  • Neurotrophins differentially regulate voltage-gated ion channels. 
  • Novel inhibitory action of tunicamycin homologues suggests a role for dynamic protein fatty acylation in growth cone-mediated neurite extension. 
  • Posttranslational membrane attachment and dynamic fatty acylation of a neuronal growth cone protein, GAP-43. 
  • Primary structure and transcriptional regulation of GAP-43, a protein associated with nerve growth. 
  • Protein kinase C activity, translocation, and conventional isoforms in aging rat brain. 
  • Protein kinase C inhibition by tamoxifen antagonizes manic-like behavior in rats: implications for the development of novel therapeutics for bipolar disorder. 
  • Role of GAP-43 in sequestering phosphatidylinositol 4,5-bisphosphate to Raft bilayers. 
  • Selective conservation of GAP-43 structure in vertebrate evolution. 
  • Spinal axon regeneration evoked by replacing two growth cone proteins in adult neurons. 
  • The activity of a highly promiscuous AP-1 element can be confined to neurons by a tissue-selective repressive element.