Cyclin A

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  Subject Areas on Research

  • Dimethylfumarate effectively inhibits lymphangiogenesis via p21 induction and G1 cell cycle arrest. 
  • Error-prone polyploid mitosis during normal Drosophila development. 
  • Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication. 
  • Mitotic phosphatase activity is required for MCC maintenance during the spindle checkpoint. 
  • Network calisthenics: control of E2F dynamics in cell cycle entry. 
  • Overexpression of p21(waf1) in human T-cell lymphotropic virus type 1-infected cells and its association with cyclin A/cdk2. 
  • Partial agonist activity of the progesterone receptor antagonist RU486 mediated by an amino-terminal domain coactivator and phosphorylation of serine400. 
  • Podocyte cell cycle regulation and proliferation in collapsing glomerulopathies. 
  • Preferential re-replication of Drosophila heterochromatin in the absence of geminin. 
  • Stimulation of human and rat islet beta-cell proliferation with retention of function by the homeodomain transcription factor Nkx6.1. 
  • The transcription factor B-Myb is maintained in an inhibited state in target cells through its interaction with the nuclear corepressors N-CoR and SMRT. 
  • p38 MAP kinase inhibition enables proliferation of adult mammalian cardiomyocytes.