Cyclin B
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Subject Areas on Research
- A combinatorial mechanism for determining the specificity of E2F activation and repression.
- A cyclin B homolog in S. cerevisiae: chronic activation of the Cdc28 protein kinase by cyclin prevents exit from mitosis.
- A role for Cdc2- and PP2A-mediated regulation of Emi2 in the maintenance of CSF arrest.
- A role for PP1 in the Cdc2/Cyclin B-mediated positive feedback activation of Cdc25.
- Across the meiotic divide - CSF activity in the post-Emi2/XErp1 era.
- Aven-dependent activation of ATM following DNA damage.
- B-cyclin/CDKs regulate mitotic spindle assembly by phosphorylating kinesins-5 in budding yeast.
- Cdc2 and Mos regulate Emi2 stability to promote the meiosis I-meiosis II transition.
- Cdc28 tyrosine phosphorylation and the morphogenesis checkpoint in budding yeast.
- Checkpoints couple transcription network oscillator dynamics to cell-cycle progression.
- Combinatorial control of cyclin B1 nuclear trafficking through phosphorylation at multiple sites.
- Control of cyclin B1 localization through regulated binding of the nuclear export factor CRM1.
- Differential susceptibility of yeast S and M phase CDK complexes to inhibitory tyrosine phosphorylation.
- Distinct mechanisms control the stability of the related S-phase cyclins Clb5 and Clb6.
- Evidence that a free-running oscillator drives G1 events in the budding yeast cell cycle.
- Gene expression disruptions of organism versus organ in Drosophila species hybrids.
- Inhibition of the anaphase-promoting complex by the Xnf7 ubiquitin ligase.
- Intrinsic and cyclin-dependent kinase-dependent control of spindle pole body duplication in budding yeast.
- Maintenance of G2 arrest in the Xenopus oocyte: a role for 14-3-3-mediated inhibition of Cdc25 nuclear import.
- Mitotic phosphatase activity is required for MCC maintenance during the spindle checkpoint.
- Multi-step control of spindle pole body duplication by cyclin-dependent kinase.
- Nuclear import of Cdk/cyclin complexes: identification of distinct mechanisms for import of Cdk2/cyclin E and Cdc2/cyclin B1.
- PP1-mediated dephosphorylation of phosphoproteins at mitotic exit is controlled by inhibitor-1 and PP1 phosphorylation.
- Parametric modeling of cellular state transitions as measured with flow cytometry.
- Phosphorylation of the cyclin b1 cytoplasmic retention sequence by mitogen-activated protein kinase and Plx.
- Reconciling conflicting models for global control of cell-cycle transcription.
- Requirement of the prolyl isomerase Pin1 for the replication checkpoint.
- Restraint of apoptosis during mitosis through interdomain phosphorylation of caspase-2.
- Stimulation of human and rat islet beta-cell proliferation with retention of function by the homeodomain transcription factor Nkx6.1.
- Temperature-Induced uncoupling of cell cycle regulators.
- The role of actin in spindle orientation changes during the Saccharomyces cerevisiae cell cycle.
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Keywords of People
- Lew, Daniel Julio, James B. Duke Distinguished Professor of Pharmacology and Cancer Biology, Cell Biology