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Subject Areas on Research
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A Nanopore Sequencing-Based Assay for Rapid Detection of Gene Fusions.
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A Phase II trial of gemcitabine and mitoxantrone for patients with acute myeloid leukemia in first relapse.
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A novel triple purge strategy for eliminating chronic myelogenous leukemia (CML) cells from autografts.
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Alpha-glycosylceramides enhance the antitumor cytotoxicity of hepatic lymphocytes obtained from cancer patients by activating CD3-CD56+ NK cells in vitro.
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An array of 60,000 antibodies for proteome-scale antibody generation and target discovery.
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Antagonism of SET using OP449 enhances the efficacy of tyrosine kinase inhibitors and overcomes drug resistance in myeloid leukemia.
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Architecture of the human regulatory network derived from ENCODE data.
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Atypical features of familial hemophagocytic lymphohistiocytosis.
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BMI1 enhancer polymorphism underlies chromosome 10p12.31 association with childhood acute lymphoblastic leukemia.
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BP1, a new homeobox gene, is frequently expressed in acute leukemias.
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Bcr-Abl kinase modulates the translation regulators ribosomal protein S6 and 4E-BP1 in chronic myelogenous leukemia cells via the mammalian target of rapamycin.
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Bcr-Abl-mediated protection from apoptosis downstream of mitochondrial cytochrome c release.
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CX3CR1 tyrosine sulfation enhances fractalkine-induced cell adhesion.
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Cadmium- and chromium-induced oxidative stress, DNA damage, and apoptotic cell death in cultured human chronic myelogenous leukemic K562 cells, promyelocytic leukemic HL-60 cells, and normal human peripheral blood mononuclear cells.
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Cell-type specific and combinatorial usage of diverse transcription factors revealed by genome-wide binding studies in multiple human cells.
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Characterization of cord blood natural killer and lymphokine activated killer lymphocytes following ex vivo cellular engineering.
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DNA methylation alterations in response to pesticide exposure in vitro.
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Defining fibronectin's cell adhesion synergy site by site-directed mutagenesis.
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Distinct functions of two isoforms of a homeobox gene, BP1 and DLX7, in the regulation of the beta-globin gene.
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Drug uptake and pharmacological modulation of drug sensitivity in leukemia by AQP9.
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Engineering a BCR-ABL-activated caspase for the selective elimination of leukemic cells.
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Expression profiling using microarrays fabricated by an ink-jet oligonucleotide synthesizer.
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Force measurements of the alpha5beta1 integrin-fibronectin interaction.
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Galpha12 and Galpha13 negatively regulate the adhesive functions of cadherin.
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Genome-wide quantification of the effects of DNA methylation on human gene regulation.
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Genome-wide study of DNA methylation alterations in response to diazinon exposure in vitro.
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Gfi-1B controls human erythroid and megakaryocytic differentiation by regulating TGF-beta signaling at the bipotent erythro-megakaryocytic progenitor stage.
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Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements.
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Histone modifications at human enhancers reflect global cell-type-specific gene expression.
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Identification and characterization of cell type-specific and ubiquitous chromatin regulatory structures in the human genome.
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Identification of cis-acting elements and splicing factors involved in the regulation of BIM Pre-mRNA splicing.
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Inhibition of polysome assembly enhances imatinib activity against chronic myelogenous leukemia and overcomes imatinib resistance.
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Iron-responsive miR-485-3p regulates cellular iron homeostasis by targeting ferroportin.
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Low-dose methotrexate results in the selective accumulation of aminoimidazole carboxamide ribotide in an erythroblastoid cell line.
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Morphing low-affinity ligands into high-avidity nanoparticles by thermally triggered self-assembly of a genetically encoded polymer.
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Non-viral charge reversal vectors for pDNA delivery.
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Pyrvinium selectively targets blast phase-chronic myeloid leukemia through inhibition of mitochondrial respiration.
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Scanning Quadrupole Data-Independent Acquisition, Part A: Qualitative and Quantitative Characterization.
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Screening Regulatory Element Function with CRISPR/Cas9-based Epigenome Editing.
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Targeted disruption of β-arrestin 2-mediated signaling pathways by aptamer chimeras leads to inhibition of leukemic cell growth.
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Targeting aldehyde dehydrogenase: a potential approach for cell labeling.
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Targeting of the MNK-eIF4E axis in blast crisis chronic myeloid leukemia inhibits leukemia stem cell function.
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The HDAC inhibitor SB939 overcomes resistance to BCR-ABL kinase Inhibitors conferred by the BIM deletion polymorphism in chronic myeloid leukemia.
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Tumor-specific recognition of human myeloma cells by idiotype-induced CD8(+) T cells.
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TβRIII/β-arrestin2 regulates integrin α5β1 trafficking, function, and localization in epithelial cells.
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Unexpected multivalent display of proteins by temperature triggered self-assembly of elastin-like polypeptide block copolymers.
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Visualizing Engrafted Human Cancer and Therapy Responses in Immunodeficient Zebrafish.
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WHIM syndrome caused by a single amino acid substitution in the carboxy-tail of chemokine receptor CXCR4.
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microRNA miR-144 modulates oxidative stress tolerance and associates with anemia severity in sickle cell disease.
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Keywords of People