Genetic Predisposition to Disease

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  Subject Areas on Research

  • 172G>T variant in the 5' untranslated region of DNA repair gene RAD51 reduces risk of squamous cell carcinoma of the head and neck and interacts with a P53 codon 72 variant. 
  • 5-HTTLPR polymorphism impacts human cingulate-amygdala interactions: a genetic susceptibility mechanism for depression. 
  • A 32 kb critical region excluding Y402H in CFH mediates risk for age-related macular degeneration. 
  • A 6-Mb high-resolution physical and transcription map encompassing the hereditary prostate cancer 1 (HPC1) region. 
  • A Chinese family affected by lynch syndrome caused by MLH1 mutation. 
  • A Common Variant in MIR182 Is Associated With Primary Open-Angle Glaucoma in the NEIGHBORHOOD Consortium. 
  • A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers. 
  • A Cross-Cancer Genetic Association Analysis of the DNA Repair and DNA Damage Signaling Pathways for Lung, Ovary, Prostate, Breast, and Colorectal Cancer. 
  • A Functional Interleukin-18 Haplotype Predicts Depression and Anxiety through Increased Threat-Related Amygdala Reactivity in Women but Not Men. 
  • A Functional Polymorphism (rs2494752) in the AKT1 Promoter Region and Gastric Adenocarcinoma Risk in an Eastern Chinese Population. 
  • A Genetic Porcine Model of Cancer. 
  • A Genetic Response Score for Hydrochlorothiazide Use: Insights From Genomics and Metabolomics Integration. 
  • A Gilbert's syndrome UGT1A1 variant confers susceptibility to tranilast-induced hyperbilirubinemia. 
  • A Guide for a Cardiovascular Genomics Biorepository: the CATHGEN Experience. 
  • A Heritable Missense Polymorphism in CDKN2A Confers Strong Risk of Childhood Acute Lymphoblastic Leukemia and Is Preferentially Selected during Clonal Evolution. 
  • A KRAS-variant in ovarian cancer acts as a genetic marker of cancer risk. 
  • A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk. 
  • A PGC1β genetic variant associated with nevus count and melanoma mortality. 
  • A PheWAS approach in studying HLA-DRB1*1501. 
  • A SAGE study of apolipoprotein E3/3, E3/4 and E4/4 allele-specific gene expression in hippocampus in Alzheimer disease. 
  • A TGF-β1 genetic variant at the miRNA187 binding site significantly modifies risk of HPV16-associated oropharyngeal cancer. 
  • A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease. 
  • A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk. 
  • A biopsychosocial-spiritual model of chronic pain in adults with sickle cell disease. 
  • A coding and non-coding transcriptomic perspective on the genomics of human metabolic disease. 
  • A combination of molecular markers and clinical features improve the classification of pancreatic cysts. 
  • A combined genomewide linkage scan of 1,233 families for prostate cancer-susceptibility genes conducted by the international consortium for prostate cancer genetics. 
  • A common polymorphism in extracellular superoxide dismutase affects cardiopulmonary disease risk by altering protein distribution. 
  • A common polymorphism in the 3'UTR of cyclooxygenase 2/prostaglandin synthase 2 gene and risk of lung cancer in a Chinese population. 
  • A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome. 
  • A common variant on chromosome 9p21 affects the risk of myocardial infarction. 
  • A comparison of strain-related susceptibility in two murine recovery models of global cerebral ischemia. 
  • A comprehensive gene-environment interaction analysis in Ovarian Cancer using genome-wide significant common variants. 
  • A comprehensive iterative approach is highly effective in diagnosing individuals who are exome negative. 
  • A computational method to classify variants of uncertain significance using functional assay data with application to BRCA1. 
  • A content analysis of the views of genetics professionals on race, ancestry, and genetics. 
  • A deficit in astroglial organization causes the impaired reactive sprouting in human apolipoprotein E4 targeted replacement mice. 
  • A family study of chronic post-traumatic stress disorder following rape trauma. 
  • A formalin-fixed paraffin-embedded (FFPE)-based prognostic signature to predict metastasis in clinically low risk stage I/II microsatellite stable colorectal cancer. 
  • A founder mutation in the Ashkenazi Jewish population affecting messenger RNA splicing of the CCM2 gene causes cerebral cavernous malformations. 
  • A framework for annotating human genome in disease context. 
  • A functional NQO1 609C>T polymorphism and risk of gastrointestinal cancers: a meta-analysis. 
  • A functional alternative splicing mutation in human tryptophan hydroxylase-2. 
  • A functional polymorphism in the 5HTR2C gene associated with stress responses also predicts incident cardiovascular events. 
  • A functional polymorphism in the CEBPE gene promoter influences acute lymphoblastic leukemia risk through interaction with the hematopoietic transcription factor Ikaros. 
  • A functional variant at miRNA-122 binding site in IL-1a 3' UTR predicts risk of recurrence in patients with oropharyngeal cancer. 
  • A functional variant at miRNA-122 binding site in IL-1α 3' UTR predicts risk and HPV-positive tumours of oropharyngeal cancer. 
  • A functional variant at the miR-885-5p binding site of CASP3 confers risk of both index and second primary malignancies in patients with head and neck cancer. 
  • A functional variant at the miRNA binding site in E2F1 gene is associated with risk and tumor HPV16 status of oropharynx squamous cell carcinoma. 
  • A functional variant in the CFI gene confers a high risk of age-related macular degeneration. 
  • A genetic hypothesis for Chiari I malformation with or without syringomyelia. 
  • A genetic risk score based on direct associations with coronary heart disease improves coronary heart disease risk prediction in the Atherosclerosis Risk in Communities (ARIC), but not in the Rotterdam and Framingham Offspring, Studies. 
  • A genetic stochastic process model for genome-wide joint analysis of biomarker dynamics and disease susceptibility with longitudinal data. 
  • A genetic variant in the APE1/Ref-1 gene promoter -141T/G may modulate risk of glioblastoma in a Chinese Han population. 
  • A genome scan for hypertension susceptibility loci in populations of Chinese and Japanese origins. 
  • A genome-wide association scan (GWAS) for mean telomere length within the COGS project: identified loci show little association with hormone-related cancer risk. 
  • A genome-wide association study for coronary artery disease identifies a novel susceptibility locus in the major histocompatibility complex. 
  • A genome-wide association study for myopia and refractive error identifies a susceptibility locus at 15q25. 
  • A genome-wide association study identified a novel genetic loci STON1-GTF2A1L/LHCGR/FSHR for bilaterality of neovascular age-related macular degeneration. 
  • A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2. 
  • A genome-wide association study identifies a susceptibility locus for refractive errors and myopia at 15q14. 
  • A genome-wide association study identifies novel loci for paclitaxel-induced sensory peripheral neuropathy in CALGB 40101. 
  • A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24. 
  • A genome-wide association study identifies susceptibility variants for type 2 diabetes in Han Chinese. 
  • A genome-wide association study implicates the APOE locus in nonpathological cognitive ageing. 
  • A genome-wide association study of antidepressant response in Koreans. 
  • A genome-wide association study of corneal astigmatism: The CREAM Consortium. 
  • A genome-wide association study of depressive symptoms. 
  • A genome-wide association study of myasthenia gravis. 
  • A genome-wide association study of resistance to HIV infection in highly exposed uninfected individuals with hemophilia A. 
  • A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium. 
  • A genome-wide association study of variants associated with acquisition of Staphylococcus aureus bacteremia in a healthcare setting. 
  • A genome-wide association study reveals a quantitative trait locus of adiponectin on CDH13 that predicts cardiometabolic outcomes. 
  • A genome-wide association study suggests new evidence for an association of the NADPH Oxidase 4 (NOX4) gene with severe diabetic retinopathy in type 2 diabetes. 
  • A genome-wide linkage and association scan reveals novel loci for autism. 
  • A genome-wide scan for common alleles affecting risk for autism. 
  • A genome-wide search for linkage to asthma phenotypes in the genetics of asthma international network families: evidence for a major susceptibility locus on chromosome 2p. 
  • A genomewide screen in multiplex rheumatoid arthritis families suggests genetic overlap with other autoimmune diseases. 
  • A genomic approach to colon cancer risk stratification yields biologic insights into therapeutic opportunities. 
  • A haplotype at the PARK3 locus influences onset age for Parkinson's disease: the GenePD study. 
  • A high frequency of activating extracellular domain ERBB2 (HER2) mutation in micropapillary urothelial carcinoma. 
  • A high-density screen for linkage in multiple sclerosis. 
  • A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC. 
  • A homopolymer polymorphism in the TOMM40 gene contributes to cognitive performance in aging. 
  • A hybrid CFHR3-1 gene causes familial C3 glomerulopathy. 
  • A hybrid framework for genome wide epistasis discovery. 
  • A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants. 
  • A large set of Finnish affected sibling pair families with type 2 diabetes suggests susceptibility loci on chromosomes 6, 11, and 14. 
  • A locus for generalized tonic-clonic seizure susceptibility maps to chromosome 10q25-q26. 
  • A low-frequency variant at 8q24.21 is strongly associated with risk of oligodendroglial tumors and astrocytomas with IDH1 or IDH2 mutation. 
  • A major predisposition locus for severe obesity, at 4p15-p14. 
  • A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. 
  • A meta-analysis of gene expression signatures of blood pressure and hypertension. 
  • A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2. 
  • A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease. 
  • A model for susceptibility polymorphisms for complex diseases: apolipoprotein E and Alzheimer disease. 
  • A multicenter study of BRD2 as a risk factor for juvenile myoclonic epilepsy. 
  • A multistate model for the genetic analysis of the ageing process. 
  • A mutation in TNNC1-encoded cardiac troponin C, TNNC1-A31S, predisposes to hypertrophic cardiomyopathy and ventricular fibrillation. 
  • A mutation in cartilage oligomeric matrix protein (COMP) causes early-onset osteoarthritis in a large kindred study. 
  • A mutation in the interferon-gamma-receptor gene and susceptibility to mycobacterial infection. 
  • A needle in a haystack: Sturge-Weber syndrome gene discovery. 
  • A new approach for rare variation collapsing on functional protein domains implicates specific genic regions in ALS. 
  • A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorder. 
  • A novel functional polymorphism C1797G in the MDM2 promoter is associated with risk of bladder cancer in a Chinese population. 
  • A novel human disease with abnormal prion protein sensitive to protease. 
  • A novel mutation in the gene encoding noggin is not causative in human neural tube defects. 
  • A novel mutation of the ACADM gene (c.145C>G) associated with the common c.985A>G mutation on the other ACADM allele causes mild MCAD deficiency: a case report. 
  • A novel test for recessive contributions to complex diseases implicates Bardet-Biedl syndrome gene BBS10 in idiopathic type 2 diabetes and obesity. 
  • A pathobiological role of the insulin receptor in chronic lymphocytic leukemia. 
  • A polygenic p factor for major psychiatric disorders. 
  • A pooled case-control study of the apolipoprotein E (APOE) gene in age-related maculopathy. 
  • A preliminary analysis of interactions between genotype, retrospective ADHD symptoms, and initial reactions to smoking in a sample of young adults. 
  • A preliminary exploration of college smokers' reactions to nicotine dependence genetic susceptibility feedback. 
  • A pri-miR-218 variant and risk of cervical carcinoma in Chinese women. 
  • A promoter sequence variant of ZNF750 is linked with familial psoriasis. 
  • A putative causal relationship between genetically determined female body shape and posttraumatic stress disorder. 
  • A randomized controlled trial of disclosing genetic risk information for Alzheimer disease via telephone. 
  • A randomized noninferiority trial of condensed protocols for genetic risk disclosure of Alzheimer's disease. 
  • A rare penetrant mutation in CFH confers high risk of age-related macular degeneration. 
  • A recessive variant of XRCC4 predisposes to non- BRCA1/2 breast cancer in chinese women and impairs the DNA damage response via dysregulated nuclear localization. 
  • A replicated molecular genetic basis for subtyping antisocial behavior in children with attention-deficit/hyperactivity disorder. 
  • A role of matrix metalloproteinase-8 in atherosclerosis. 
  • A second major histocompatibility complex susceptibility locus for multiple sclerosis. 
  • A single nucleotide polymorphism in the alcohol dehydrogenase 7 gene (alanine to glycine substitution at amino acid 92) is associated with the risk of squamous cell carcinoma of the head and neck. 
  • A single-center experience with ganciclovir-resistant cytomegalovirus in lung transplant recipients: treatment and outcome. 
  • A single-gene cause in 29.5% of cases of steroid-resistant nephrotic syndrome. 
  • A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. 
  • A study of the TNF/LTA/LTB locus and susceptibility to severe malaria in highland papuan children and adults. 
  • A susceptibility gene for affective disorders and the response of the human amygdala. 
  • A systematic genetic assessment of 1,433 sequence variants of unknown clinical significance in the BRCA1 and BRCA2 breast cancer-predisposition genes. 
  • A targeted genetic association study of epithelial ovarian cancer susceptibility. 
  • A variant at a potentially functional microRNA-binding site in BRIP1 was associated with risk of squamous cell carcinoma of the head and neck. 
  • A variant in FTO shows association with melanoma risk not due to BMI. 
  • A variant of the DNA repair gene XRCC3 and risk of squamous cell carcinoma of the head and neck: a case-control analysis. 
  • A variant of the LRP4 gene affects the risk of chronic lymphocytic leukaemia transformation to Richter syndrome. 
  • ABCB1/MDR1 gene determines susceptibility and phenotype in ulcerative colitis: discrimination of critical variants using a gene-wide haplotype tagging approach. 
  • ABO blood group and risk of epithelial ovarian cancer within the Ovarian Cancer Association Consortium. 
  • ADHD and smoking: from genes to brain to behavior. 
  • AMD and the alternative complement pathway: genetics and functional implications. 
  • APC I1307K and the risk of prostate cancer. 
  • APOE and the regulation of microglial nitric oxide production: a link between genetic risk and oxidative stress. 
  • APOE epsilon variation in multiple sclerosis susceptibility and disease severity: some answers. 
  • APOE genotype is a risk factor for neuropathy severity in diabetic patients. 
  • APOE is a major susceptibility gene for Alzheimer's disease. 
  • APOE related hippocampal shape alteration in geriatric depression. 
  • APOE ε4-TOMM40 '523 haplotypes and the risk of Alzheimer's disease in older Caucasian and African Americans. 
  • APOE/TOMM40 genetic loci, white matter hyperintensities, and cerebral microbleeds. 
  • APOE2 allele increased in tardive dyskinesia. 
  • APOL1 kidney disease risk variants cause cytotoxicity by depleting cellular potassium and inducing stress-activated protein kinases. 
  • APOL1 risk alleles among individuals with CKD in Northern Tanzania: A pilot study. 
  • ARID5B genetic polymorphisms contribute to racial disparities in the incidence and treatment outcome of childhood acute lymphoblastic leukemia. 
  • ASCO/SSO review of current role of risk-reducing surgery in common hereditary cancer syndromes. 
  • ASCO/SSO review of current role of risk-reducing surgery in common hereditary cancer syndromes. 
  • ATM polymorphisms predict severe radiation pneumonitis in patients with non-small cell lung cancer treated with definitive radiation therapy. 
  • ATM: genome stability, neuronal development, and cancer cross paths. 
  • Aberrant monocyte prostaglandin synthase 2 (PGS2) expression in type 1 diabetes before and after disease onset. 
  • Abnormal creatine transport of mutations in monocarboxylate transporter 12 (MCT12) found in patients with age-related cataract can be partially rescued by exogenous chaperone CD147. 
  • Absence of PTEN germ-line mutations in men with a potential inherited predisposition to prostate cancer. 
  • Absence of a correlation of androgen receptor gene CAG repeat length and prostate cancer risk in an African-American population. 
  • Absence of association of asporin polymorphisms and osteoarthritis susceptibility in US Caucasians. 
  • Absence of genomic BRCA1 and BRCA2 rearrangements in Ashkenazi breast and ovarian cancer families. 
  • Accuracy of self-reports of fecal occult blood tests and test results among individuals in the carpentry trade. 
  • Activating mutation in MET oncogene in familial colorectal cancer. 
  • Additional evidence that PGAP1 loss of function causes autosomal recessive global developmental delay and encephalopathy. 
  • Adenylate cyclase 7 is implicated in the biology of depression and modulation of affective neural circuitry. 
  • Adherence to Recommended Risk Management among Unaffected Women with a BRCA Mutation. 
  • Admixture mapping identifies 8q24 as a prostate cancer risk locus in African-American men. 
  • Adrenomedullin signaling pathway polymorphisms and adverse pregnancy outcomes. 
  • Adult height is associated with increased risk of ovarian cancer: a Mendelian randomisation study. 
  • Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis. 
  • Adult outcomes of childhood bullying victimization. 
  • Advances in inherited cancers: Introduction. 
  • Advantage of rare HLA supertype in HIV disease progression. 
  • African Ancestry Analysis and Admixture Genetic Mapping for Proliferative Diabetic Retinopathy in African Americans. 
  • African-American heredity prostate cancer study: a model for genetic research. 
  • African-derived genetic polymorphisms in TNFAIP3 mediate risk for autoimmunity. 
  • Age at onset in two common neurodegenerative diseases is genetically controlled. 
  • Age-Dependent Effects of Catechol-O-Methyltransferase (COMT) Gene Val158Met Polymorphism on Language Function in Developing Children. 
  • Age-related maculopathy: a genomewide scan with continued evidence of susceptibility loci within the 1q31, 10q26, and 17q25 regions. 
  • Age-related susceptibility to severe malaria associated with galectin-2 in highland Papuans. 
  • Aggregate Effects of Intraocular Pressure and Cup-to-Disc Ratio Genetic Variants on Glaucoma in a Multiethnic Asian Population. 
  • Aging-related atherosclerosis is exacerbated by arterial expression of tumor necrosis factor receptor-1: evidence from mouse models and human association studies. 
  • Alleles of a reelin CGG repeat do not convey liability to autism in a sample from the CPEA network. 
  • Allelic differences between Europeans and Chinese for CREB1 SNPs and their implications in gene expression regulation, hippocampal structure and function, and bipolar disorder susceptibility. 
  • Allelic variation in human gene expression. 
  • Allelic variations in gene expression. 
  • Alpha₁-antitrypsin deficiency-related alleles Z and S and the risk of Wegener's granulomatosis. 
  • Alterations of the X-linked lymphoproliferative disease gene SH2D1A in common variable immunodeficiency syndrome. 
  • Alternative splicing in Acad8 resulting a mitochondrial defect and progressive hepatic steatosis in mice. 
  • Alternative splicing in disease and therapy. 
  • Alzheimer's Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci. 
  • Alzheimer's disease susceptibility genes APOE and TOMM40, and brain white matter integrity in the Lothian Birth Cohort 1936. 
  • Alzheimer's disease susceptibility genes APOE and TOMM40, and hippocampal volumes in the Lothian birth cohort 1936. 
  • Alzheimer's disease: the genetics of risk. 
  • American Gastroenterological Association Institute Guideline on the Diagnosis and Management of Lynch Syndrome. 
  • American Society of Clinical Oncology Expert Statement: collection and use of a cancer family history for oncology providers. 
  • Amino acid-level signal-to-noise analysis of incidentally identified variants in genes associated with long QT syndrome during pediatric whole exome sequencing reflects background genetic noise. 
  • Amyotrophic lateral sclerosis, lead, and genetic susceptibility: polymorphisms in the delta-aminolevulinic acid dehydratase and vitamin D receptor genes. 
  • Amyotrophic lateral sclerosis: an emerging era of collaborative gene discovery. 
  • An Atlas of Genetic Variation Linking Pathogen-Induced Cellular Traits to Human Disease. 
  • An Exome Sequencing Study to Assess the Role of Rare Genetic Variation in Pulmonary Fibrosis. 
  • An FTO variant is associated with Type 2 diabetes in South Asian populations after accounting for body mass index and waist circumference. 
  • An analysis of single nucleotide polymorphisms of 125 DNA repair genes in the Texas genome-wide association study of lung cancer with a replication for the XRCC4 SNPs. 
  • An analysis paradigm for investigating multi-locus effects in complex disease: examination of three GABA receptor subunit genes on 15q11-q13 as risk factors for autistic disorder. 
  • An application of Random Forests to a genome-wide association dataset: methodological considerations & new findings. 
  • An association between the 4G polymorphism in the PAI-1 promoter and the development of aggressive fibromatosis (desmoid tumor) in familial adenomatous polyposis patients. 
  • An autosomal genomic screen for dementia in an extended Amish family. 
  • An inherited variable poly-T repeat genotype in TOMM40 in Alzheimer disease. 
  • An integrated encyclopedia of DNA elements in the human genome. 
  • An integrative genomics approach identifies novel pathways that influence candidaemia susceptibility. 
  • An intergenic risk locus containing an enhancer deletion in 2q35 modulates breast cancer risk by deregulating IGFBP5 expression. 
  • An miR-502-binding site single-nucleotide polymorphism in the 3'-untranslated region of the SET8 gene is associated with early age of breast cancer onset. 
  • Analysis combining correlated glaucoma traits identifies five new risk loci for open-angle glaucoma. 
  • Analysis of 60 reported glioma risk SNPs replicates published GWAS findings but fails to replicate associations from published candidate-gene studies. 
  • Analysis of ALDH1A2, CYP26A1, CYP26B1, CRABP1, and CRABP2 in human neural tube defects suggests a possible association with alleles in ALDH1A2. 
  • Analysis of European mitochondrial haplogroups with Alzheimer disease risk. 
  • Analysis of LOXL1 polymorphisms in a Saudi Arabian population with pseudoexfoliation glaucoma. 
  • Analysis of non-synonymous-coding variants of Parkinson's disease-related pathogenic and susceptibility genes in East Asian populations. 
  • Analysis of over 10,000 Cases finds no association between previously reported candidate polymorphisms and ovarian cancer outcome. 
  • Analysis of the RELN gene as a genetic risk factor for autism. 
  • Analysis of the gene coding for the BRCA2-interacting protein PALB2 in hereditary prostate cancer. 
  • Analysis of the prostate cancer-susceptibility locus HPC20 in 172 families affected by prostate cancer. 
  • Angiopoietin-1 promotes atherosclerosis by increasing the proportion of circulating Gr1+ monocytes. 
  • Angiotensin-converting enzyme gene and retinal arteriolar narrowing: the Funagata Study. 
  • Animal models in the research of abdominal aortic aneurysms development. 
  • Anthracycline-related cardiomyopathy after childhood cancer: role of polymorphisms in carbonyl reductase genes--a report from the Children's Oncology Group. 
  • Apolipoprotein E controls the risk and age at onset of Parkinson disease. 
  • Apolipoprotein E epsilon4 allele and outcomes of traumatic spinal cord injury. 
  • Apolipoprotein E gene and early age-related maculopathy: the Atherosclerosis Risk in Communities Study. 
  • Apolipoprotein E genotype and neurodevelopmental sequelae of infant cardiac surgery. 
  • Apolipoprotein E genotype as a determinant of survival in chronic lymphocytic leukemia. 
  • Apolipoprotein E genotype, cardiovascular biomarkers and risk of stroke: systematic review and meta-analysis of 14,015 stroke cases and pooled analysis of primary biomarker data from up to 60,883 individuals. 
  • Apolipoprotein E is associated with age at onset of amyotrophic lateral sclerosis. 
  • Apolipoprotein E modifies neurological outcome by affecting cerebral edema but not hematoma size after intracerebral hemorrhage in humans. 
  • Apolipoprotein E ε4 allele interacts with sex and cognitive status to influence all-cause and cause-specific mortality in U.S. older adults. 
  • Apolipoprotein E4 polymorphism as a genetic predisposition to delirium in critically ill patients. 
  • Apolipoprotein epsilon 4 genotype is associated with less improvement in cognitive function five years after cardiac surgery: a retrospective cohort study. 
  • Application of a rank-based genetic association test to age-at-onset data from the Collaborative Study on the Genetics of Alcoholism study. 
  • Application of rare variant transmission disequilibrium tests to epileptic encephalopathy trio sequence data. 
  • Applications of RNA interference high-throughput screening technology in cancer biology and virology. 
  • Applications of targeted gene capture and next-generation sequencing technologies in studies of human deafness and other genetic disabilities. 
  • Arabidopsis SNI1 and RAD51D regulate both gene transcription and DNA recombination during the defense response. 
  • Are associations between parental divorce and children's adjustment genetically mediated? An adoption study. 
  • Assessing associations between the AURKA-HMMR-TPX2-TUBG1 functional module and breast cancer risk in BRCA1/2 mutation carriers. 
  • Assessing the Causality between Blood Pressure and Retinal Vascular Caliber through Mendelian Randomisation. 
  • Assessment of diabetic nephropathy in the Akita mouse. 
  • Assessment of individuals with BRCA1 and BRCA2 large rearrangements in high-risk breast and ovarian cancer families. 
  • Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with risk of clear cell ovarian cancer. 
  • Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study. 
  • Association Between Use of the 21-Gene Recurrence Score Assay and Receipt of Chemotherapy Among Medicare Beneficiaries With Early-Stage Breast Cancer, 2005-2009. 
  • Association analysis of 9,560 prostate cancer cases from the International Consortium of Prostate Cancer Genetics confirms the role of reported prostate cancer associated SNPs for familial disease. 
  • Association analysis of chromosome 15 gabaa receptor subunit genes in autistic disorder. 
  • Association and interactions between DNA repair gene polymorphisms and adult glioma. 
  • Association between PARP-1 V762A polymorphism and cancer susceptibility: a meta-analysis. 
  • Association between a functional polymorphism (-1195T>C) in the IGFBP5 promoter and head and neck cancer risk. 
  • Association between a rare novel TP53 variant (rs78378222) and melanoma, squamous cell carcinoma of head and neck and lung cancer susceptibility in non-Hispanic Whites. 
  • Association between common germline genetic variation in 94 candidate genes or regions and risks of invasive epithelial ovarian cancer. 
  • Association between familial atrial fibrillation and risk of new-onset atrial fibrillation. 
  • Association between functional polymorphisms in genes involved in the MAPK signaling pathways and cutaneous melanoma risk. 
  • Association between invasive ovarian cancer susceptibility and 11 best candidate SNPs from breast cancer genome-wide association study. 
  • Association between miRNA-binding site polymorphisms in double-strand break repair genes and risk of recurrence in patients with squamous cell carcinomas of the non-oropharynx. 
  • Association between novel PLCE1 variants identified in published esophageal cancer genome-wide association studies and risk of squamous cell carcinoma of the head and neck. 
  • Association between p53 Arg72Pro polymorphism and colorectal cancer risk: a meta-analysis. 
  • Association between putative functional variants in the PSMB9 gene and risk of melanoma--re-analysis of published melanoma genome-wide association studies. 
  • Association between single nucleotide polymorphisms in ERCC4 and risk of squamous cell carcinoma of the head and neck. 
  • Association between the ERCC5 Asp1104His polymorphism and cancer risk: a meta-analysis. 
  • Association mapping of the high-grade myopia MYP3 locus reveals novel candidates UHRF1BP1L, PTPRR, and PPFIA2. 
  • Association of ALS with head injury, cigarette smoking and APOE genotypes. 
  • Association of BRCA1 functional single nucleotide polymorphisms with risk of differentiated thyroid carcinoma. 
  • Association of Common Genetic Polymorphisms with Melanoma Patient IL-12p40 Blood Levels, Risk, and Outcomes. 
  • Association of Epstein-Barr virus with systemic lupus erythematosus: effect modification by race, age, and cytotoxic T lymphocyte-associated antigen 4 genotype. 
  • Association of Genetic Variants With Primary Open-Angle Glaucoma Among Individuals With African Ancestry. 
  • Association of HLA alleles with Plasmodium falciparum severity in Malian children. 
  • Association of IL6ST (gp130) Polymorphism with Functional Outcome Following Spontaneous Intracerebral Hemorrhage. 
  • Association of LEP G2548A and LEPR Q223R polymorphisms with cancer susceptibility: evidence from a meta-analysis. 
  • Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study. 
  • Association of SLC11A1 with tuberculosis and interactions with NOS2A and TLR2 in African-Americans and Caucasians. 
  • Association of TGF-beta1 genetic variants with HPV16-positive oropharyngeal cancer. 
  • Association of Variants in BAG3 With Cardiomyopathy Outcomes in African American Individuals. 
  • Association of Vitamin D receptor Fok I polymorphism with the risk of prostate cancer: a meta-analysis. 
  • Association of XRCC1 polymorphisms and risk of differentiated thyroid carcinoma: a case-control analysis. 
  • Association of a functional CD19 polymorphism with susceptibility to systemic sclerosis. 
  • Association of a p73 exon 2 G4C14-to-A4T14 polymorphism with risk of squamous cell carcinoma of the head and neck. 
  • Association of exome sequences with plasma C-reactive protein levels in >9000 participants. 
  • Association of gene variants of the renin-angiotensin system with accelerated hippocampal volume loss and cognitive decline in old age. 
  • Association of genetic polymorphisms with risk of renal injury after coronary bypass graft surgery. 
  • Association of genetic variants in the HDL receptor, SR-B1, with abnormal lipids in women with coronary artery disease. 
  • Association of genetic variants of O6-methylguanine-DNA methyltransferase with risk of lung cancer in non-Hispanic Whites. 
  • Association of genetic variation in IKZF1, ARID5B, and CEBPE and surrogates for early-life infections with the risk of acute lymphoblastic leukemia in Hispanic children. 
  • Association of granulomatosis with polyangiitis (Wegener's) with HLA-DPB1*04 and SEMA6A gene variants: evidence from genome-wide analysis. 
  • Association of hsp70-2 and hsp-hom gene polymorphisms with risk of acute high-altitude illness in a Chinese population. 
  • Association of maternal IL-1 receptor antagonist intron 2 gene polymorphism and preterm birth. 
  • Association of p53 codon 72 polymorphism with risk of second primary malignancy in patients with squamous cell carcinoma of the head and neck. 
  • Association of parental hypertension with concentrations of select biomarkers in nonhypertensive offspring. 
  • Association of parental obesity with concentrations of select systemic biomarkers in nonobese offspring: the Framingham Heart Study. 
  • Association of polygenic risk score with the risk of chronic lymphocytic leukemia and monoclonal B-cell lymphocytosis. 
  • Association of polymorphisms in one-carbon metabolizing genes and lung cancer risk: a case-control study in Chinese population. 
  • Association of polymorphisms in the apolipoprotein E region with susceptibility to and progression of multiple sclerosis. 
  • Association of risk-reducing surgery in BRCA1 or BRCA2 mutation carriers with cancer risk and mortality. 
  • Association of sequence variants on chromosomes 20, 11, and 5 (20q13.33, 11q23.3, and 5p15.33) with glioma susceptibility in a Chinese population. 
  • Association of single nucleotide polymorphisms on chromosome 9p21.3 with platelet reactivity: a potential mechanism for increased vascular disease. 
  • Association of single-nucleotide polymorphisms of the tau gene with late-onset Parkinson disease. 
  • Association of the FTO gene with BMI. 
  • Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. 
  • Association of the missense variant p.Arg203Trp in PACS1 as a cause of intellectual disability and seizures. 
  • Association of the trace amine associated receptor 6 (TAAR6) gene with schizophrenia and bipolar disorder in a Korean case control sample. 
  • Association of the variable number of tandem repeats polymorphism in the promoter region of the SMYD3 gene with risk of esophageal squamous cell carcinoma in relation to tobacco smoking. 
  • Association of two CASP8 polymorphisms with breast cancer risk: a meta-analysis. 
  • Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer. 
  • Association of variants in FRAP1 and PDGFRA with corneal curvature in Asian populations from Singapore. 
  • Association of vitamin D levels and risk of ovarian cancer: a Mendelian randomization study. 
  • Association study of Parkin gene polymorphisms with idiopathic Parkinson disease. 
  • Association study of common genetic variants and HIV-1 acquisition in 6,300 infected cases and 7,200 controls. 
  • Association study of genetic polymorphisms of SLC2A10 gene and type 2 diabetes in the Taiwanese population. 
  • Association study of nicotinic acetylcholine receptor genes identifies a novel lung cancer susceptibility locus near CHRNA1 in African-Americans. 
  • Associations between HLA class I alleles and the prevalence of nasopharyngeal carcinoma (NPC) among Tunisians. 
  • Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study. 
  • Associations between RNA splicing regulatory variants of stemness-related genes and racial disparities in susceptibility to prostate cancer. 
  • Associations between genetic variants in mRNA splicing-related genes and risk of lung cancer: a pathway-based analysis from published GWASs. 
  • Associations between genome-wide Native American ancestry, known risk alleles and B-cell ALL risk in Hispanic children. 
  • Associations of Lys939Gln and Ala499Val polymorphisms of the XPC gene with cancer susceptibility: a meta-analysis. 
  • Associations of PI3KR1 and mTOR polymorphisms with esophageal squamous cell carcinoma risk and gene-environment interactions in Eastern Chinese populations. 
  • Associations of genotypes and haplotypes of IL-17 with risk of gastric cancer in an eastern Chinese population. 
  • Associations of high-grade glioma with glioma risk alleles and histories of allergy and smoking. 
  • Associations of potentially functional variants in IL-6, JAKs and STAT3 with gastric cancer risk in an eastern Chinese population. 
  • Associations of prostate cancer risk variants with disease aggressiveness: results of the NCI-SPORE Genetics Working Group analysis of 18,343 cases. 
  • Atherosclerosis: a cancer of the blood vessels? 
  • Atherosclerotic risk genotypes and recurrent coronary events after myocardial infarction. 
  • Attempted replication of 50 reported asthma risk genes identifies a SNP in RAD50 as associated with childhood atopic asthma. 
  • Autism and the serotonin transporter: the long and short of it. 
  • Autism genome-wide copy number variation reveals ubiquitin and neuronal genes. 
  • Autism or a related developmental disability. 
  • Autism spectrum disorder susceptibility gene TAOK2 affects basal dendrite formation in the neocortex. 
  • AutoCSA, an algorithm for high throughput DNA sequence variant detection in cancer genomes. 
  • Automatic diagnosis of pathological myopia from heterogeneous biomedical data. 
  • Axonal neuropathy with optic atrophy is caused by mutations in mitofusin 2. 
  • B cell subsets in pristane-induced autoimmunity. 
  • BAALC expression predicts clinical outcome of de novo acute myeloid leukemia patients with normal cytogenetics: a Cancer and Leukemia Group B Study. 
  • BDNF Val66Met and spontaneous dyskinesias in non-clinical psychosis. 
  • BMI1 enhancer polymorphism underlies chromosome 10p12.31 association with childhood acute lymphoblastic leukemia. 
  • BRAF polymorphisms and the risk of ovarian cancer of low malignant potential. 
  • BRCA1 mutations in primary breast and ovarian carcinomas. 
  • BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers. 
  • BRCAPRO validation, sensitivity of genetic testing of BRCA1/BRCA2, and prevalence of other breast cancer susceptibility genes. 
  • Baseline Parameters in Clinical Trials for Nonalcoholic Steatohepatitis: Recommendations From the Liver Forum. 
  • Behavior and emotion modulation deficits in preschoolers at risk for bipolar disorder. 
  • Behavioral and neurochemical effects of wild-type and mutated human alpha-synuclein in transgenic mice. 
  • Behavioral response inhibition in psychotic disorders: diagnostic specificity, familiality and relation to generalized cognitive deficit. 
  • Beneficial IL28B genotype associated with lower frequency of hepatic steatosis in patients with chronic hepatitis C. 
  • Best cases from the AFIP: Adamantinoma of the tibia and fibula with cytogenetic analysis. 
  • Beyond Mendel: an evolving view of human genetic disease transmission. 
  • Biogenetic mechanisms predisposing to complex phenotypes in parents may function differently in their children. 
  • Biological predictors of chemotherapy-induced peripheral neuropathy (CIPN): MASCC neurological complications working group overview. 
  • Biology of aortic aneurysms and dissections. 
  • Biotic interactions. Genomics and coevolution. 
  • Biotic interactions. Genomics and coevolution. 
  • Birth Cohort, Age, and Sex Strongly Modulate Effects of Lipid Risk Alleles Identified in Genome-Wide Association Studies. 
  • Brain tumor epidemiology: consensus from the Brain Tumor Epidemiology Consortium. 
  • Brain-derived neurotrophic factor rs6265 (Val66Met) polymorphism is associated with disease severity and incidence of cardiovascular events in a patient cohort. 
  • Breast MRI radiogenomics: Current status and research implications. 
  • Breast and ovarian cancer risk and risk reduction in Jewish BRCA1/2 mutation carriers. 
  • Breast cancer risk factors differ between Asian and white women with BRCA1/2 mutations. 
  • Breast cancer risk models: a comprehensive overview of existing models, validation, and clinical applications. 
  • Breast cancer risks in individuals testing negative for a known family mutation in BRCA1 or BRCA2. 
  • Breast cancer: oophorectomy for BRCA1 ER--negative disease-an open debate. 
  • Breast medical oncologists' use of standard prognostic factors to predict a 21-gene recurrence score. 
  • Breastfeeding and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers. 
  • Brief Report: HLA-DRB1, DQA1, and DQB1 in Juvenile-Onset Systemic Sclerosis. 
  • Bromodomain protein 4 discriminates tissue-specific super-enhancers containing disease-specific susceptibility loci in prostate and breast cancer. 
  • C3 R102G polymorphism increases risk of age-related macular degeneration. 
  • CASP7 variants modify susceptibility to cervical cancer in Chinese women. 
  • CASP8 polymorphisms contribute to cancer susceptibility: evidence from a meta-analysis of 23 publications with 55 individual studies. 
  • CCL3L1 and HIV/AIDS susceptibility. 
  • CFH and VIPR2 as susceptibility loci in choroidal thickness and pachychoroid disease central serous chorioretinopathy. 
  • CKD of Uncertain Etiology: A Systematic Review. 
  • CMPK1 and RBP3 are associated with corneal curvature in Asian populations. 
  • COL1A1 and COL2A1 genes and myopia susceptibility: evidence of association and suggestive linkage to the COL2A1 locus. 
  • COMT and anxiety and cognition in children with chromosome 22q11.2 deletion syndrome. 
  • CRHBP polymorphisms predict chronic pain development following motor vehicle collision. 
  • CTLA-4 gene polymorphisms and systemic lupus erythematosus in a population-based study of whites and African-Americans in the southeastern United States. 
  • CUBN is a gene locus for albuminuria. 
  • CX3CR1-dependent renal macrophage survival promotes Candida control and host survival. 
  • Calcium Channel Mutations in Cardiac Arrhythmia Syndromes. 
  • Can the retinal microvasculature offer clues to cardiovascular risk factors in early life? 
  • Cancer and longevity--is there a trade-off? A study of cooccurrence in Danish twin pairs born 1900-1918. 
  • Cancer genetics service interest in women with a limited family history of breast cancer. 
  • Cancer susceptibility: epigenetic manifestation of environmental exposures. 
  • Cancer yield of mammography, MR, and US in high-risk women: prospective multi-institution breast cancer screening study. 
  • Candidate gene analysis of 21q22: support for S100B as a susceptibility gene for bipolar affective disorder with psychosis. 
  • Candidate gene association study for diabetic retinopathy in persons with type 2 diabetes: the Candidate gene Association Resource (CARe). 
  • Candidate genes on murine chromosome 8 are associated with susceptibility to Staphylococcus aureus infection in mice and are involved with Staphylococcus aureus septicemia in humans. 
  • Case-control association study of 14 variants of CREB1, CREBBP and CREM on diagnosis and treatment outcome in major depressive disorder and bipolar disorder. 
  • Case-control association study of 36 single-nucleotide polymorphisms within 10 candidate genes for major depression and bipolar disorder. 
  • Catechol-O-methyltransferase gene polymorphisms are associated with multiple pain-evoking stimuli. 
  • Causal Effect of Plasminogen Activator Inhibitor Type 1 on Coronary Heart Disease. 
  • Cell cycle genes and ovarian cancer susceptibility: a tagSNP analysis. 
  • Cell-type-specific enrichment of risk-associated regulatory elements at ovarian cancer susceptibility loci. 
  • Central nervous system serotonin and clustering of hostility, psychosocial, metabolic, and cardiovascular endophenotypes in men. 
  • Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease. 
  • Challenges in the phenotypic characterisation of patients in genetic studies of coronary artery disease. 
  • Characteristics of abdominal vein thrombosis in children and adults. 
  • Characteristics of missed or interval colorectal cancer and patient survival: a population-based study. 
  • Characterization of BRCA1 and BRCA2 mutations in a large United States sample. 
  • Characterization of a Human-Specific Tandem Repeat Associated with Bipolar Disorder and Schizophrenia. 
  • Charcot-Marie-Tooth with pyramidal signs is genetically heterogeneous: families with and without MFN2 mutations. 
  • Childhood gene-environment interactions and age-dependent effects of genetic variants associated with refractive error and myopia: The CREAM Consortium. 
  • Childhood socioeconomic status and serotonin transporter gene polymorphism enhance cardiovascular reactivity to mental stress. 
  • Childhood trauma and children's emerging psychotic symptoms: A genetically sensitive longitudinal cohort study. 
  • Childhood victimization and inflammation in young adulthood: A genetically sensitive cohort study. 
  • Children are not just little adults: recent advances in understanding of diffuse intrinsic pontine glioma biology. 
  • Children of Alzheimer patients: an overview. 
  • Children of persons with Alzheimer disease: what does the future hold? 
  • Chromosomal localization of two genes underlying late-infantile neuronal ceroid lipofuscinosis. 
  • Chromosome 17q22-q24 and multiple sclerosis genetic susceptibility. American-French Multiple Sclerosis Genetic Group. 
  • Chromosomes 4 and 8 implicated in a genome wide SNP linkage scan of 762 prostate cancer families collected by the ICPCG. 
  • Chronic family stress moderates the association between a TOMM40 variant and triglyceride levels in two independent Caucasian samples. 
  • Cigarette smoking strongly modifies the association of LOC387715 and age-related macular degeneration. 
  • Cigarette smoking, glutathione-s-transferase M1 and t1 genetic polymorphisms, and breast cancer risk (United States). 
  • Circulating vitamin D concentration and risk of seven cancers: Mendelian randomisation study. 
  • Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer. 
  • Classification of epilepsy syndromes and role of genetic factors. 
  • Clinical and Genetic Risk Prediction of Subsequent CNS Tumors in Survivors of Childhood Cancer: A Report From the COG ALTE03N1 Study. 
  • Clinical and functional findings in choroideremia due to complete deletion of the CHM gene. 
  • Clinical and genetic correlates of growth differentiation factor 15 in the community. 
  • Clinical and pathologic features of familial interstitial pneumonia. 
  • Clinical characteristics of African-American men with hereditary prostate cancer: the AAHPC Study. 
  • Clinical decision making regarding leiomyomata: what we need in the next millenium. 
  • Clinical genomic testing: getting it right. 
  • Clinical interpretation and implications of whole-genome sequencing. 
  • Clinical outcome of isolated serous tubal intraepithelial carcinomas (STIC). 
  • Clinical risk factors for age-related macular degeneration: a systematic review and meta-analysis. 
  • Clinically relevant changes in family history of cancer over time. 
  • Clonal and microclonal mutational heterogeneity in high hyperdiploid acute lymphoblastic leukemia. 
  • Cognitive outcomes and age of detection of severe mucopolysaccharidosis type 1. 
  • Combination of exome sequencing and immune testing confirms Aicardi-Goutières syndrome type 5 in a challenging pediatric neurology case. 
  • Combinatorial Mismatch Scan (CMS) for loci associated with dementia in the Amish. 
  • Combined and interactive effects of environmental and GWAS-identified risk factors in ovarian cancer. 
  • Combined effects of E2F1 and E2F2 polymorphisms on risk and early onset of squamous cell carcinoma of the head and neck. 
  • Combined effects of the p53 and p73 polymorphisms on lung cancer risk. 
  • Combined genome-wide scan for prostate cancer susceptibility genes. 
  • Combined genotype and haplotype tests for region-based association studies. 
  • Comment on 'A PAX6 gene polymorphism is associated with genetic predisposition to extreme myopia'. 
  • Commentary on "Distinguishing genetic from nongenetic medical tests: some implications for antidiscrimination legislation" (J.S. Alper and J. Beckwith) 
  • Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD. 
  • Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk. 
  • Common Genetic Variation and Susceptibility to Ovarian Cancer: Current Insights and Future Directions. 
  • Common MFRP sequence variants are not associated with moderate to high hyperopia, isolated microphthalmia, and high myopia. 
  • Common alleles in candidate susceptibility genes associated with risk and development of epithelial ovarian cancer. 
  • Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2. 
  • Common familial colorectal cancer linked to chromosome 7q31: a genome-wide analysis. 
  • Common genetic determinants of breast-cancer risk in East Asian women: a collaborative study of 23 637 breast cancer cases and 25 579 controls. 
  • Common genetic determinants of vitamin D insufficiency: a genome-wide association study. 
  • Common genetic variants associated with resting oxygenation in chronic obstructive pulmonary disease. 
  • Common genetic variants associated with telomere length confer risk for neuroblastoma and other childhood cancers. 
  • Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. 
  • Common genetic variants on 5p14.1 associate with autism spectrum disorders. 
  • Common genetic variants on 8q24 contribute to susceptibility to bladder cancer in a Chinese population. 
  • Common genetic variation and human traits. 
  • Common genetic variation and susceptibility to partial epilepsies: a genome-wide association study. 
  • Common human ANK2 variant confers in vivo arrhythmia phenotypes. 
  • Common human genetic variants and HIV-1 susceptibility: a genome-wide survey in a homogeneous African population. 
  • Common mechanisms underlying refractive error identified in functional analysis of gene lists from genome-wide association study results in 2 European British cohorts. 
  • Common minor histocompatibility antigen discovery based upon patient clinical outcomes and genomic data. 
  • Common non-synonymous polymorphisms in the BRCA1 Associated RING Domain (BARD1) gene are associated with breast cancer susceptibility: a case-control analysis. 
  • Common variants at 19p13 are associated with susceptibility to ovarian cancer. 
  • Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. 
  • Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. 
  • Common variants at the CHEK2 gene locus and risk of epithelial ovarian cancer. 
  • Common variants conferring risk of schizophrenia. 
  • Common variants in ACYP2 influence susceptibility to cisplatin-induced hearing loss. 
  • Common variants near ABCA1 and in PMM2 are associated with primary open-angle glaucoma. 
  • Common variants near ABCA1, AFAP1 and GMDS confer risk of primary open-angle glaucoma. 
  • Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma. 
  • Communication of genetic risk information to daughters in families with fragile X syndrome: the parent's perspective. 
  • Comparative genomic evidence for the involvement of schizophrenia risk genes in antipsychotic effects. 
  • Comparative phenotypic and CARD15 mutational analysis among African American, Hispanic, and White children with Crohn's disease. 
  • Comparing Coordinated Versus Sequential Salpingo-Oophorectomy for BRCA1 and BRCA2 Mutation Carriers With Breast Cancer. 
  • Compelling evidence for a prostate cancer gene at 22q12.3 by the International Consortium for Prostate Cancer Genetics. 
  • Complement factor H variant increases the risk of age-related macular degeneration. 
  • Complete effect-profile assessment in association studies with multiple genetic and multiple environmental factors. 
  • Complete genomic screen for disease susceptibility loci in nuclear families. 
  • Complete genomic screen in Parkinson disease: evidence for multiple genes. 
  • Complex trait genetics of refractive error. 
  • Comprehensive annotation of BRCA1 and BRCA2 missense variants by functionally validated sequence-based computational prediction models. 
  • Comprehensive association analysis of APOE regulatory region polymorphisms in Alzheimer disease. 
  • Comprehensive genomic profiling of relapsed and metastatic adenoid cystic carcinomas by next-generation sequencing reveals potential new routes to targeted therapies. 
  • Comprehensive serial molecular profiling of an "N of 1" exceptional non-responder with metastatic prostate cancer progressing to small cell carcinoma on treatment. 
  • Computational approach to radiogenomics of breast cancer: Luminal A and luminal B molecular subtypes are associated with imaging features on routine breast MRI extracted using computer vision algorithms. 
  • Concept of disease in geriatric psychiatry. 
  • Concordance of genetic variation that increases risk for anxiety disorders and posttraumatic stress disorders and that influences their underlying neurocircuitry. 
  • Conditional deletion of TrkB but not BDNF prevents epileptogenesis in the kindling model. 
  • Conditional knockout of Fgf13 in murine hearts increases arrhythmia susceptibility and reveals novel ion channel modulatory roles. 
  • Confirmation of a second locus for CMT2 and evidence for additional genetic heterogeneity. 
  • Connecting genetic risk to disease end points through the human blood plasma proteome. 
  • Consortium analysis of gene and gene-folate interactions in purine and pyrimidine metabolism pathways with ovarian carcinoma risk. 
  • Consumption of meat is associated with higher fasting glucose and insulin concentrations regardless of glucose and insulin genetic risk scores: a meta-analysis of 50,345 Caucasians. 
  • Contemplating genetic feedback regarding lung cancer susceptibility. 
  • Contribution of three components to individual cancer risk predicting breast cancer risk in Italy. 
  • Convergent effects of mouse Pet-1 deletion and human PET-1 variation on amygdala fear and threat processing. 
  • Convergent patterns of association between phenylalanine hydroxylase variants and schizophrenia in four independent samples. 
  • Converging pathways in neurodegeneration, from genetics to mechanisms. 
  • Coping with genetic testing for breast cancer susceptibility. 
  • Copy number variation at chromosome 5q21.2 is associated with intraocular pressure. 
  • Coronary artery disease is associated with Alzheimer disease neuropathology in APOE4 carriers. 
  • Correlations between apolipoprotein E epsilon4 gene dose and whole brain atrophy rates. 
  • Corroboration of a familial chordoma locus on chromosome 7q and evidence of genetic heterogeneity using single nucleotide polymorphisms (SNPs). 
  • Cost-effectiveness of HLA-B*1502 genotyping in adult patients with newly diagnosed epilepsy in Singapore. 
  • Crohn's disease IRGM risk alleles are associated with altered gene expression in human tissues. 
  • Current epidemiology of diabetic retinopathy and diabetic macular edema. 
  • Current international perspectives on hematopoietic stem cell transplantation for inherited metabolic disorders. 
  • Cutting edge: TLR4 deficiency confers susceptibility to lethal oxidant lung injury. 
  • Cutting edge: critical role of intracellular osteopontin in antifungal innate immune responses. 
  • Cyclin D1 G870A polymorphism and breast cancer risk: a meta-analysis comprising 9,911 cases and 11,171 controls. 
  • Cystic fibrosis gene mutations and pancreatitis risk: relation to epithelial ion transport and trypsin inhibitor gene mutations. 
  • Cystic fibrosis mutations and genetic predisposition to idiopathic chronic pancreatitis. 
  • Cytochrome P450 1A1 (CYP1A1) gene polymorphisms and cervical cancer risk: a meta-analysis. 
  • Cytochrome P450 1A1 (CYP1A1) gene polymorphisms and ovarian cancer risk: a meta-analysis. 
  • Cytochrome P450 1A1 gene polymorphisms and endometrial cancer risk: a meta-analysis. 
  • Cytokine gene polymorphisms and the outcome of invasive candidiasis: a prospective cohort study. 
  • Cytokine gene polymorphisms are not associated with bronchiolitis obliterans syndrome or survival after lung transplant. 
  • Cytokine polymorphic analyses indicate ethnic differences in the allelic distribution of interleukin-2 and interleukin-6. 
  • D-Dimer in African Americans: Whole Genome Sequence Analysis and Relationship to Cardiovascular Disease Risk in the Jackson Heart Study. 
  • DAOA variants and schizophrenia: influence on diagnosis and treatment outcomes. 
  • DAOA variants on diagnosis and response to treatment in patients with major depressive disorder and bipolar disorder. 
  • DNA copy number variants of known glaucoma genes in relation to primary open-angle glaucoma. 
  • DNA glycosylases involved in base excision repair may be associated with cancer risk in BRCA1 and BRCA2 mutation carriers. 
  • DNA mismatch repair network gene polymorphism as a susceptibility factor for pancreatic cancer. 
  • DNA repair gene ERCC1 and ERCC2/XPD polymorphisms and risk of squamous cell carcinoma of the head and neck. 
  • DNA repair gene XPC genotypes/haplotypes and risk of lung cancer in a Chinese population. 
  • DNA repair gene XPD polymorphism and lung cancer risk: a meta-analysis. 
  • DNA repair phenotype and cancer susceptibility--a mini review. 
  • DNA repair: a double-edged sword. 
  • DRD2-related TaqIA polymorphism modulates motivation to smoke. 
  • DTNBP1 haplotype influences baseline assessment scores of schizophrenic in-patients. 
  • De novo and inherited private variants in MAP1B in periventricular nodular heterotopia. 
  • De novo mutations in ATP1A3 cause alternating hemiplegia of childhood. 
  • De novo mutations in epileptic encephalopathies. 
  • Decoding the role of regulatory element polymorphisms in complex disease. 
  • Decreased cognitive function in extended family members from the single late-onset-Alzheimer's-disease pedigree. 
  • Decreasing age at prostate cancer diagnosis over successive generations in prostate cancer families. 
  • Deep Sequencing of Three Loci Implicated in Large-Scale Genome-Wide Association Study Smoking Meta-Analyses. 
  • Deep phenotyping in zebrafish reveals genetic and diet-induced adiposity changes that may inform disease risk. 
  • Defective neuronal sprouting by human apolipoprotein E4 is a gain-of-negative function. 
  • Deficiencies in the Fanconi anemia DNA damage response pathway increase sensitivity to HPV-associated head and neck cancer. 
  • Deficiency of Adenosine Deaminase 2 (DADA2), an Inherited Cause of Polyarteritis Nodosa and a Mimic of Other Systemic Rheumatologic Disorders. 
  • Deficiency of asparagine synthetase causes congenital microcephaly and a progressive form of encephalopathy. 
  • Deficient Mismatch Repair and the Role of Immunotherapy in Metastatic Colorectal Cancer. 
  • Defining aggressive prostate cancer using a 12-gene model. 
  • Defining the contribution of CNTNAP2 to autism susceptibility. 
  • Definition of a functional single nucleotide polymorphism in the cell migration inhibitory gene MIIP that affects the risk of breast cancer. 
  • Delineating the requirements for spontaneous DNA damage resistance pathways in genome maintenance and viability in Saccharomyces cerevisiae. 
  • Dense genotyping of immune-related loci in idiopathic inflammatory myopathies confirms HLA alleles as the strongest genetic risk factor and suggests different genetic background for major clinical subgroups. 
  • Depression, Stressful Life Events, and the Impact of Variation in the Serotonin Transporter: Findings from the National Longitudinal Study of Adolescent to Adult Health (Add Health). 
  • Depressive symptoms moderate the influence of the apolipoproteine epsilon4 allele on cognitive decline in a sample of community dwelling older adults. 
  • Depressive-like behavior and high alcohol drinking co-occur in the FH/WJD rat but appear to be under independent genetic control. 
  • Descriptive epidemiology and risk factors for head and neck cancer. 
  • Design and Implementation of the International Genetics and Translational Research in Transplantation Network. 
  • Design of the Genetics of Early Onset Cardiovascular Disease (GENECARD) study. 
  • Detecting local haplotype sharing and haplotype association. 
  • Detection of clinically relevant genetic variants in autism spectrum disorder by whole-genome sequencing. 
  • Detection of subclinical fabry disease in patients presenting with hypertrophic cardiomyopathy. 
  • Development and evaluation of a genetic risk score for obesity. 
  • Developmental mediation of genetic variation in response to the Fast Track prevention program. 
  • Developmental origins and environmental influences--Introduction. NIEHS symposium. 
  • Developments in the scientific understanding of lupus. 
  • Diabetes, Pancreatogenic Diabetes, and Pancreatic Cancer. 
  • Diabetic nephropathy: of mice and men. 
  • Differences in K-ras and p53 gene mutations among pancreatic adenocarcinomas associated with regional environmental pollution. 
  • Differential effects of MDM2 SNP309 polymorphism on breast cancer risk along with race: a meta-analysis. 
  • Differential survival with Alzheimer disease. 
  • Differential susceptibility to adolescent externalizing trajectories: examining the interplay between CHRM2 and peer group antisocial behavior. 
  • Disclosing Pleiotropic Effects During Genetic Risk Assessment for Alzheimer Disease: A Randomized Trial. 
  • Disclosure of APOE genotype for risk of Alzheimer's disease. 
  • Discovering genetic variants in Crohn's disease by exploring genomic regions enriched of weak association signals. 
  • Discovery and fine mapping of serum protein loci through transethnic meta-analysis. 
  • Discovery and refinement of loci associated with lipid levels. 
  • Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure. 
  • Discriminatory accuracy and potential clinical utility of genomic profiling for breast cancer risk in BRCA-negative women. 
  • Disparities in the burden, outcomes, and care of chronic kidney disease. 
  • Dissection of a quantitative trait locus for PR interval duration identifies Tnni3k as a novel modulator of cardiac conduction. 
  • Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking. 
  • Distinct neurological disorders with ATP1A3 mutations. 
  • Distinguishing arrhythmogenic right ventricular cardiomyopathy/dysplasia-associated mutations from background genetic noise. 
  • Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium. 
  • Does Type 2 Diabetes Genetic Testing and Counseling Reduce Modifiable Risk Factors? A Randomized Controlled Trial of Veterans. 
  • Does race modify the association between CYP1B1 Val432Leu polymorphism and breast cancer risk? A critical appraisal of a recent meta-analysis. 
  • Dopamine polymorphisms and depressive symptoms predict foods intake. Results from a nationally representative sample. 
  • Drosophila, genetic screens, and cardiac function. 
  • Ductal carcinoma in situ in BRCA mutation carriers. 
  • Dural sinus thrombosis associated with activated protein C resistance: MR imaging findings and proband identification. 
  • Dysbindin gene (DTNBP1) and schizophrenia in Korean population. 
  • EMK: a novel program for family-based allelic and genotypic association tests on quantitative traits. 
  • ERCC6/CSB gene polymorphisms and lung cancer risk. 
  • ESR1/SYNE1 polymorphism and invasive epithelial ovarian cancer risk: an Ovarian Cancer Association Consortium study. 
  • Early behavioral intervention, brain plasticity, and the prevention of autism spectrum disorder. 
  • Early onset prostate cancer has a significant genetic component. 
  • Editing the Epigenome: Reshaping the Genomic Landscape. 
  • Effect of 5-haplotype of dysbindin gene (DTNBP1) polymorphisms for the susceptibility to bipolar I disorder. 
  • Effect of APOE and CD33 on Cognitive Decline. 
  • Effect of Genetic African Ancestry on eGFR and Kidney Disease. 
  • Effect of genetic testing for risk of type 2 diabetes mellitus on health behaviors and outcomes: study rationale, development and design. 
  • Effect of genetic variation in the nicotinic receptor genes on risk for posttraumatic stress disorder. 
  • Effect of standard nicotinamide in the prevention of type 1 diabetes in first degree relatives of persons with type 1 diabetes. 
  • Effect of the 5-HTTLPR polymorphism on posttraumatic stress disorder, depression, anxiety, and quality of life among Iraq and Afghanistan veterans. 
  • Effects of 5HTTLPR on cardiovascular response to an emotional stressor. 
  • Effects of MDM2 promoter polymorphisms and p53 codon 72 polymorphism on risk and age at onset of squamous cell carcinoma of the head and neck. 
  • Effects of covariates: a summary of Group 5 contributions. 
  • Effects of family history and apolipoprotein E epsilon4 status on cognitive decline in the absence of Alzheimer dementia: the Cache County Study. 
  • Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. 
  • Efficacy, safety and pharmacokinetics of a new high-purity factor X concentrate in women and girls with hereditary factor X deficiency. 
  • Electrocardiographic Early Repolarization: A Scientific Statement From the American Heart Association. 
  • Electrophysiological basis and genetics of Brugada syndrome. 
  • Elevated LRRK2 autophosphorylation in brain-derived and peripheral exosomes in LRRK2 mutation carriers. 
  • Elevated antisaccade error rate as an intermediate phenotype for psychosis across diagnostic categories. 
  • Elevated risk of prostate cancer among men with Lynch syndrome. 
  • Eligible and not eligible studies in the recent meta-analysis about p53 polymorphism and breast cancer risk. 
  • Elucidating the role of genomics in neonatal sepsis. 
  • Endocytic disturbances distinguish among subtypes of Alzheimer's disease and related disorders. 
  • Endovascular Repair of Internal Mammary Artery Aneurysms in 2 Sisters with SMAD3 Mutation. 
  • Enhanced maternal origin of the 22q11.2 deletion in velocardiofacial and DiGeorge syndromes. 
  • Enrichment of putative PAX8 target genes at serous epithelial ovarian cancer susceptibility loci. 
  • Environmental epigenomics and disease susceptibility. 
  • Environmental genomics: a key to understanding biology, pathophysiology and disease. 
  • Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer. 
  • Epigenetic profiling identifies novel genes for ascending aortic aneurysm formation with bicuspid aortic valves. 
  • Epigenetic regulation of AXL and risk of childhood asthma symptoms. 
  • Epigenetics and autism spectrum disorder: A report of an autism case with mutation in H1 linker histone HIST1H1E and literature review. 
  • Epigenome-wide association of PTSD from heterogeneous cohorts with a common multi-site analysis pipeline. 
  • Epistasis between a set of variations located in the TAAR6 and HSP-70 genes toward schizophrenia and response to antipsychotic treatment. 
  • Epithelial-Mesenchymal Transition (EMT) Gene Variants and Epithelial Ovarian Cancer (EOC) Risk. 
  • Equilibrative nucleoside transporter 1 gene polymorphisms and clinical outcomes following acute coronary syndromes: findings from the PLATelet inhibition and patient Outcomes (PLATO) study. 
  • Erythrocyte CR1 expression level does not correlate with a HindIII restriction fragment length polymorphism in Africans; implications for studies on malaria susceptibility. 
  • Estimation of the effects of smoking and DNA repair capacity on coefficients of a carcinogenesis model for lung cancer. 
  • Estrogen pathway polymorphisms in relation to primary open angle glaucoma: an analysis accounting for gender from the United States. 
  • Estrogen receptor beta rs1271572 polymorphism and invasive ovarian carcinoma risk: pooled analysis within the Ovarian Cancer Association Consortium. 
  • Ethical issues in identifying and recruiting participants for familial genetic research. 
  • Ethical issues of predictive genetic testing for diabetes. 
  • Ethnicity and arrhythmia susceptibility. 
  • European Collaborative Project on Affective Disorders: interactions between genetic and psychosocial vulnerability factors. 
  • Evaluating genetic susceptibility to Staphylococcus aureus bacteremia in African Americans using admixture mapping. 
  • Evaluating the Impact of Functional Genetic Variation on HIV-1 Control. 
  • Evaluating the ovarian cancer gonadotropin hypothesis: a candidate gene study. 
  • Evaluation of HLA polymorphisms in relation to schizophrenia risk and infectious exposure. 
  • Evaluation of Lipin 2 as a candidate gene for autosomal dominant 1 high-grade myopia. 
  • Evaluation of Primary Angle-Closure Glaucoma Susceptibility Loci in Patients with Early Stages of Angle-Closure Disease. 
  • Evaluation of SLC11A1 as an inflammatory bowel disease candidate gene. 
  • Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot". 
  • Evaluation of clustering and genotype distribution for replication in genome wide association studies: the age-related eye disease study. 
  • Evaluation of established breast cancer risk factors as modifiers of BRCA1 or BRCA2: a multi-center case-only analysis. 
  • Evaluation of the beta2-adrenergic receptor gene as a candidate glaucoma gene in 2 ancestral populations. 
  • Evaluation of the role of Nurr1 in a large sample of familial Parkinson's disease. 
  • Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases. 
  • Evidence for association of SNPs in ABCB1 and CBR3, but not RAC2, NCF4, SLC28A3 or TOP2B, with chronic cardiotoxicity in a cohort of breast cancer patients treated with anthracyclines. 
  • Evidence for genetic factors in the development and progression of IgA nephropathy. 
  • Evidence for involvement of GNB1L in autism. 
  • Evidence for multiple loci from a genome scan of autism kindreds. 
  • Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index. 
  • Evidence of CNIH3 involvement in opioid dependence. 
  • Evidence of a genetic link between endometriosis and ovarian cancer. 
  • Evidence that Gsta4 modifies susceptibility to skin tumor development in mice and humans. 
  • Evidence that altered amygdala activity in schizophrenia is related to clinical state and not genetic risk. 
  • Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation. 
  • Evolution of a malaria resistance gene in wild primates. 
  • Evolving Roles of Histologic Evaluation and Molecular/Genomic Profiling in the Management of Endometrial Cancer. 
  • Examination of Potential Modifiers of the Association of APOL1 Alleles with CKD Progression. 
  • Examination of seven candidate regions for multiple sclerosis: strong evidence of linkage to chromosome 1q44. 
  • Examining the impact of genetic testing for type 2 diabetes on health behaviors: study protocol for a randomized controlled trial. 
  • Exercise has a disproportionate role in the pathogenesis of arrhythmogenic right ventricular dysplasia/cardiomyopathy in patients without desmosomal mutations. 
  • Exome Sequence Analysis of 14 Families With High Myopia. 
  • Exome chip meta-analysis identifies novel loci and East Asian-specific coding variants that contribute to lipid levels and coronary artery disease. 
  • Exome genotyping arrays to identify rare and low frequency variants associated with epithelial ovarian cancer risk. 
  • Exome sequencing followed by large-scale genotyping fails to identify single rare variants of large effect in idiopathic generalized epilepsy. 
  • Exome sequencing followed by large-scale genotyping suggests a limited role for moderately rare risk factors of strong effect in schizophrenia. 
  • Exome sequencing identifies distinct mutational patterns in liver fluke-related and non-infection-related bile duct cancers. 
  • Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction. 
  • Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma. 
  • Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways. 
  • Exon 3 polymorphisms and haplotypes of O6-methylguanine-DNA methyltransferase and risk of bladder cancer in southern China: a case-control analysis. 
  • Exonic deletions in AUTS2 cause a syndromic form of intellectual disability and suggest a critical role for the C terminus. 
  • Exonuclease 1 (EXO1) gene variation and melanoma risk. 
  • Expanding the clinical phenotype of individuals with a 3-bp in-frame deletion of the NF1 gene (c.2970_2972del): an update of genotype-phenotype correlation. 
  • Experimental models of human carcinogenesis. 
  • Explaining racial differences in prostate cancer in the United States: sociology or biology? 
  • Explicating heterogeneity of complex traits has strong potential for improving GWAS efficiency. 
  • Exploration of a hypothesized independent association of a common 9p21.3 gene variant and ischemic stroke in patients with and without angiographic coronary artery disease. 
  • Exploratory analysis of Fas gene polymorphisms in pediatric osteosarcoma patients. 
  • Exploring the association of glyceraldehyde-3-phosphate dehydrogenase gene and Alzheimer disease. 
  • Expression of A20 by dendritic cells preserves immune homeostasis and prevents colitis and spondyloarthritis. 
  • Expression of nucleotide excision repair genes and the risk for squamous cell carcinoma of the head and neck. 
  • Expression of nucleotide excision repair proteins in lymphocytes as a marker of susceptibility to squamous cell carcinomas of the head and neck. 
  • FAS and FASLG genetic variants and risk for second primary malignancy in patients with squamous cell carcinoma of the head and neck. 
  • FASTSNP: an always up-to-date and extendable service for SNP function analysis and prioritization. 
  • Facial pain with localized and widespread manifestations: separate pathways of vulnerability. 
  • Failure to replicate previously reported genetic associations with sporadic temporal lobe epilepsy: where to from here? 
  • Familial aggregation of age-related macular degeneration in the Utah population. 
  • Familial clustering and subsequent incidence of atrial fibrillation among first-degree relatives in Denmark. 
  • Familial clustering of intracerebral hemorrhage: a prospective study in North Carolina. 
  • Familial idiopathic interstitial pneumonia: histopathology and survival in 30 patients. 
  • Familial influence and childhood trauma in female alcoholism. 
  • Family history and TOMM40 '523 interactive associations with memory in middle-aged and Alzheimer's disease cohorts. 
  • Family history of cancer and risk of sporadic differentiated thyroid carcinoma. 
  • Family history, near work, outdoor activity, and myopia in Singapore Chinese preschool children. 
  • Fanconi anemia gene variants in therapy-related myeloid neoplasms. 
  • Fas single nucleotide polymorphisms and risk of thyroid and salivary gland carcinomas: a case-control analysis. 
  • Fatigue correlates with LRRK2 G2385R variant in Chinese Parkinson's disease patients. 
  • Feasibility and yield of screening in relatives from familial pancreatic cancer families. 
  • Feasibility of a bilateral 4000-6000 Hz notch as a phenotype for genetic association analysis. 
  • Fibroblast growth factor 20 polymorphisms and haplotypes strongly influence risk of Parkinson disease. 
  • Fibromyalgia, mood disorders, and intense creative energy: A1AT polymorphisms are not always silent. 
  • Finding the missing heritability of complex diseases. 
  • Fine mapping of genetic variants in BIN1, CLU, CR1 and PICALM for association with cerebrospinal fluid biomarkers for Alzheimer's disease. 
  • Fine mapping of the chromosome 12 late-onset Alzheimer disease locus: potential genetic and phenotypic heterogeneity. 
  • Fine-mapping of the 5p15.33, 6p22.1-p21.31, and 15q25.1 regions identifies functional and histology-specific lung cancer susceptibility loci in African-Americans. 
  • Fine-mapping the putative chromosome 17q21-22 prostate cancer susceptibility gene to a 10 cM region based on linkage analysis. 
  • First family-based test for association of neuregulin with bipolar affective disorder. 
  • Fluoxetine response in children with autistic spectrum disorders: correlation with familial major affective disorder and intellectual achievement. 
  • Folate metabolism genes, dietary folate and response to antidepressant medications in late-life depression. 
  • Follow-up examination of linkage and association to chromosome 1q43 in multiple sclerosis. 
  • Four polymorphisms in cytochrome P450 1A1 (CYP1A1) gene and breast cancer risk: a meta-analysis. 
  • Fractures in children with Pompe disease: a potential long-term complication. 
  • Functional Analysis and Fine Mapping of the 9p22.2 Ovarian Cancer Susceptibility Locus. 
  • Functional characterization of a promoter polymorphism in APE1/Ref-1 that contributes to reduced lung cancer susceptibility. 
  • Functional genetic screen of human diversity reveals that a methionine salvage enzyme regulates inflammatory cell death. 
  • Functional genome-wide siRNA screen identifies KIAA0586 as mutated in Joubert syndrome. 
  • Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans. 
  • Functional impact of global rare copy number variation in autism spectrum disorders. 
  • Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus. 
  • Functional polymorphisms in the insulin-like binding protein-3 gene may modulate susceptibility to differentiated thyroid carcinoma in Caucasian Americans. 
  • Functional polymorphisms of CHRNA3 predict risks of chronic obstructive pulmonary disease and lung cancer in Chinese. 
  • Functional polymorphisms of JWA gene are associated with risk of bladder cancer. 
  • Functional polymorphisms of base excision repair genes XRCC1 and APEX1 predict risk of radiation pneumonitis in patients with non-small cell lung cancer treated with definitive radiation therapy. 
  • Functional polymorphisms of matrix metalloproteinase-9 are associated with risk of occurrence and metastasis of lung cancer. 
  • Functional repeats (TGYCC)n in the p53-inducible gene 3 (PIG3) promoter and susceptibility to squamous cell carcinoma of the head and neck. 
  • Functional single nucleotide polymorphisms of the RASSF3 gene and susceptibility to squamous cell carcinoma of the head and neck. 
  • Functional single-nucleotide polymorphisms in the BRCA1 gene and risk of salivary gland carcinoma. 
  • Functional variants in DCAF4 associated with lung cancer risk in European populations. 
  • Functional variants in TBX2 are associated with a syndromic cardiovascular and skeletal developmental disorder. 
  • Functional variants in TNFAIP8 associated with cervical cancer susceptibility and clinical outcomes. 
  • Functional variants in the low-density lipoprotein receptor gene are associated with clear cell renal cell carcinoma susceptibility. 
  • Functional variations in the ATM gene and susceptibility to differentiated thyroid carcinoma. 
  • Fungal infection counters insecticide resistance in African malaria mosquitoes. 
  • Further evidence for a role of the ADRB2 gene in risk for posttraumatic stress disorder. 
  • Further exclusion of FSHD1B from the telomeric region of 10q. 
  • Further investigation of linkage disequilibrium SNPs and their ability to identify associated susceptibility loci. 
  • Future directions in idiopathic pulmonary fibrosis research. An NHLBI workshop report. 
  • Fuzzy set analyses of genetic determinants of health and disability status. 
  • GALC deletions increase the risk of primary open-angle glaucoma: the role of Mendelian variants in complex disease. 
  • GATA2 is associated with familial early-onset coronary artery disease. 
  • GLIOGENE an International Consortium to Understand Familial Glioma. 
  • GSTM1 polymorphism, GSTT1 polymorphism, and cervical cancer risk: a meta-analysis. 
  • GSTT1 and GSTP1 polymorphisms and breast cancer risk: a meta-analysis. 
  • GWAS Identifies New Loci for Painful Temporomandibular Disorder: Hispanic Community Health Study/Study of Latinos. 
  • GWAS in childhood acute lymphoblastic leukemia reveals novel genetic associations at chromosomes 17q12 and 8q24.21. 
  • GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer. 
  • GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium. 
  • GWAS-identified colorectal cancer susceptibility locus associates with disease prognosis. 
  • Gamma radiation-induced apoptosis, G2 delay, and the risk of salivary and thyroid carcinomas--a preliminary report. 
  • Gamma-radiation sensitivity and risk of glioma. 
  • Gene by sex interaction in the etiology of coronary heart disease and the preceding metabolic syndrome. 
  • Gene expression elucidates functional impact of polygenic risk for schizophrenia. 
  • Gene expression in the rectus abdominus muscle of patients with and without pelvic organ prolapse. 
  • Gene expression profiles accurately predict outcome following liver resection in patients with metastatic colorectal cancer. 
  • Gene identification in Alzheimer's disease. 
  • Gene polymorphisms and susceptibility to coronary artery disease. 
  • Gene set analysis of survival following ovarian cancer implicates macrolide binding and intracellular signaling genes. 
  • Gene-centric association study of acute chest syndrome and painful crisis in sickle cell disease patients. 
  • Gene-centric meta-analysis of lipid traits in African, East Asian and Hispanic populations. 
  • Gene-environment interactions in cancer epidemiology: a National Cancer Institute Think Tank report. 
  • Gene-environment interactions in psychiatry: joining forces with neuroscience. 
  • Gene-gene Interaction Analyses for Atrial Fibrillation. 
  • Gene-gene interaction between FGF20 and MAOB in Parkinson disease. 
  • Gene-ontology enrichment analysis in two independent family-based samples highlights biologically plausible processes for autism spectrum disorders. 
  • Gene-smoking interactions in multiple Rho-GTPase pathway genes in an early-onset coronary artery disease cohort. 
  • Genes Involved in Neurodevelopment, Neuroplasticity, and Bipolar Disorder: CACNA1C, CHRNA1, and MAPK1. 
  • Genes and Environmental Exposures in Veterans with Amyotrophic Lateral Sclerosis: the GENEVA study. Rationale, study design and demographic characteristics. 
  • Genes and environment in neonatal intraventricular hemorrhage. 
  • Genetic Architecture of Primary Open-Angle Glaucoma in Individuals of African Descent: The African Descent and Glaucoma Evaluation Study III. 
  • Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations. 
  • Genetic Basis of Health Disparity in Childhood Nephrotic Syndrome. 
  • Genetic Data from Nearly 63,000 Women of European Descent Predicts DNA Methylation Biomarkers and Epithelial Ovarian Cancer Risk. 
  • Genetic Determinants of Circulating Lipoproteins in Nonalcoholic Fatty Liver Disease. 
  • Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells. 
  • Genetic Investigation Into the Differential Risk of Atrial Fibrillation Among Black and White Individuals. 
  • Genetic Predisposition to Symptomatic Lumbar Disk Herniation in Pediatric and Young Adult Patients. 
  • Genetic Sharing with Cardiovascular Disease Risk Factors and Diabetes Reveals Novel Bone Mineral Density Loci. 
  • Genetic Variants Identified from Epilepsy of Unknown Etiology in Chinese Children by Targeted Exome Sequencing. 
  • Genetic Variants Within Key Nodes of the Cascade of Antipsychotic Mechanisms: Effects on Antipsychotic Response and Schizophrenia Psychopathology in a Naturalistic Treatment Setting in Two Independent Korean and Italian Samples. 
  • Genetic Variants in Cyclooxygenase-2 Contribute to Post-treatment Pain among Endodontic Patients. 
  • Genetic Variants in the Bone Morphogenic Protein Gene Family Modify the Association between Residential Exposure to Traffic and Peripheral Arterial Disease. 
  • Genetic Variation Associated with Longer Telomere Length Increases Risk of Chronic Lymphocytic Leukemia. 
  • Genetic Variation in the Platelet Endothelial Aggregation Receptor 1 Gene Results in Endothelial Dysfunction. 
  • Genetic Variations of Circulating Adiponectin Levels Modulate Changes in Appetite in Response to Weight-Loss Diets. 
  • Genetic abnormalities in hereditary hemorrhagic telangiectasia. 
  • Genetic analysis for common complex disease. 
  • Genetic analysis of complex diseases. 
  • Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. 
  • Genetic and environmental correlates of topiramate-induced cognitive impairment. 
  • Genetic and environmental processes in young children's resilience and vulnerability to socioeconomic deprivation. 
  • Genetic and environmental risk factors for idiopathic inflammatory myopathies. 
  • Genetic and functional association of FAM5C with myocardial infarction. 
  • Genetic and functional dissection of HTRA1 and LOC387715 in age-related macular degeneration. 
  • Genetic approaches for the investigation of genes associated with coronary heart disease. 
  • Genetic architecture of artemisinin-resistant Plasmodium falciparum. 
  • Genetic association of insulin-like growth factor-1 polymorphisms with high-grade myopia in an international family cohort. 
  • Genetic association of refractive error and axial length with 15q14 but not 15q25 in the Blue Mountains Eye Study cohort. 
  • Genetic association study of adiposity and melanocortin-4 receptor (MC4R) common variants: replication and functional characterization of non-coding regions. 
  • Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci. 
  • Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. 
  • Genetic basis for clinical expression in multiple sclerosis. 
  • Genetic basis of drug-induced liver injury: present and future. 
  • Genetic basis of murine antibacterial defense to streptococcal lung infection. 
  • Genetic basis of susceptibility to drug-induced liver injury: what have we learned and where do we go from here? 
  • Genetic correlates of insight in schizophrenia. 
  • Genetic correlations between intraocular pressure, blood pressure and primary open-angle glaucoma: a multi-cohort analysis. 
  • Genetic deletion of receptor for hyaluronan-mediated motility (Rhamm) attenuates the formation of aggressive fibromatosis (desmoid tumor). 
  • Genetic determinants of age-related macular degeneration in diverse populations from the PAGE study. 
  • Genetic determinants of antithyroid drug-induced agranulocytosis by human leukocyte antigen genotyping and genome-wide association study. 
  • Genetic determinants of childhood and adult height associated with osteosarcoma risk. 
  • Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium. 
  • Genetic determinants of renal transplant outcome: where do we stand? 
  • Genetic diagnosis in Lafora disease: genotype-phenotype correlations and diagnostic pitfalls. 
  • Genetic differences in oxidative stress and inflammatory responses to diet-induced obesity do not alter liver fibrosis in mice. 
  • Genetic epidemiologic studies on age-specified traits. NIA Aging and Genetic Epidemiology Working Group. 
  • Genetic epidemiology of motor neuron disease-associated variants in the Scottish population. 
  • Genetic epidemiology of neural tube defects. 
  • Genetic evidence and integration of various data sources for classifying uncertain variants into a single model. 
  • Genetic factors in susceptibility to death: a comparative analysis of bivariate survival models. 
  • Genetic factors influencing prostate cancer risk in Norwegian men. 
  • Genetic generalized epilepsies. 
  • Genetic markers: progress and potential for cardiovascular disease. 
  • Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. 
  • Genetic modifier loci affecting survival and cardiac function in murine dilated cardiomyopathy. 
  • Genetic nature of individual frailty: comparison of two approaches. 
  • Genetic pleiotropy between age-related macular degeneration and 16 complex diseases and traits. 
  • Genetic polymorphisms and the risk of stroke after cardiac surgery. 
  • Genetic polymorphisms in DNA base-excision repair genes ADPRT, XRCC1, and APE1 and the risk of squamous cell carcinoma of the head and neck. 
  • Genetic polymorphisms in the PTPN13 gene and risk of squamous cell carcinoma of head and neck. 
  • Genetic polymorphisms in the microRNA binding-sites of the thymidylate synthase gene predict risk and survival in gastric cancer. 
  • Genetic polymorphisms in tumor necrosis factor (TNF)-alpha and TNF-beta in a population-based study of systemic lupus erythematosus: associations and interaction with the interleukin-1alpha-889 C/T polymorphism. 
  • Genetic polymorphisms of the N-acetyltransferase genes and risk of Parkinson's disease. 
  • Genetic predisposition of life-threatening antiepileptic-induced skin reactions. 
  • Genetic predisposition to higher blood pressure increases coronary artery disease risk. 
  • Genetic predisposition to lung adenocarcinoma among never-smoking Chinese with different epidermal growth factor receptor mutation status. 
  • Genetic prevalence and characteristics in children with recurrent pancreatitis. 
  • Genetic profiling to predict recurrence of early cervical cancer. 
  • Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. 
  • Genetic risk and carcinogen exposure: a common inherited defect of the carcinogen-metabolism gene glutathione S-transferase M1 (GSTM1) that increases susceptibility to bladder cancer. 
  • Genetic risk communication: experiences of adolescent girls and young women from families with fragile X syndrome. 
  • Genetic risk factors for perception of symptoms in GERD: an observational cohort study. 
  • Genetic risk factors for perinatally acquired HIV-1 infection. 
  • Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide polymorphisms. 
  • Genetic sensitivity to the environment: the case of the serotonin transporter gene and its implications for studying complex diseases and traits. 
  • Genetic signatures of exceptional longevity in humans. 
  • Genetic studies of body mass index yield new insights for obesity biology. 
  • Genetic susceptibility for chronic bronchitis in chronic obstructive pulmonary disease. 
  • Genetic susceptibility for lung cancer: interactions with gender and smoking history and impact on early detection policies. 
  • Genetic susceptibility of lung cancer associated with common variants in the 3' untranslated regions of the adenosine triphosphate-binding cassette B1 (ABCB1) and ABCC1 candidate transporter genes for carcinogen export. 
  • Genetic susceptibility testing and prophylactic oophorectomy. 
  • Genetic susceptibility to Alzheimer disease. 
  • Genetic susceptibility to benzene-induced toxicity: role of NADPH: quinone oxidoreductase-1. 
  • Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions. 
  • Genetic susceptibility to hepatic steatosis. 
  • Genetic susceptibility to lung cancer: the role of DNA damage and repair. 
  • Genetic susceptibility to tobacco carcinogenesis. 
  • Genetic susceptibility variants for chronic lymphocytic leukemia. 
  • Genetic susceptibility--molecular epidemiology of head and neck cancer. 
  • Genetic testing and tumor surveillance for children with cancer predisposition syndromes. 
  • Genetic testing for Alzheimer disease. Practical and ethical issues. 
  • Genetic testing: clinical and personal utility. 
  • Genetic variability in beta-defensins is not associated with susceptibility to Staphylococcus aureus bacteremia. 
  • Genetic variant in DNA repair gene GTF2H4 is associated with lung cancer risk: a large-scale analysis of six published GWAS datasets in the TRICL consortium. 
  • Genetic variant of PRKAA1 and gastric cancer risk in an eastern Chinese population. 
  • Genetic variant rs16430 6bp > 0bp at the microRNA-binding site in TYMS and risk of sporadic breast cancer risk in non-Hispanic white women aged ≤ 55 years. 
  • Genetic variant rs4072037 of MUC1 and gastric cancer risk in an Eastern Chinese population. 
  • Genetic variants and cellular stressors associated with exfoliation syndrome modulate promoter activity of a lncRNA within the LOXL1 locus. 
  • Genetic variants and disease: correlate or cause? 
  • Genetic variants and haplotypes of the caspase-8 and caspase-10 genes contribute to susceptibility to cutaneous melanoma. 
  • Genetic variants associated with development of TMD and its intermediate phenotypes: the genetic architecture of TMD in the OPPERA prospective cohort study. 
  • Genetic variants associated with vein graft stenosis after coronary artery bypass grafting. 
  • Genetic variants at the miR-124 binding site on the cytoskeleton-organizing IQGAP1 gene confer differential predisposition to breast cancer. 
  • Genetic variants improve breast cancer risk prediction on mammograms. 
  • Genetic variants in GTF2H1 and risk of lung cancer: a case-control analysis in a Chinese population. 
  • Genetic variants in IGF-I, IGF-II, IGFBP-3, and adiponectin genes and colon cancer risk in African Americans and Whites. 
  • Genetic variants in MGMT and risk of lung cancer in Southeastern Chinese: a haplotype-based analysis. 
  • Genetic variants in P-selectin and C-reactive protein influence susceptibility to cognitive decline after cardiac surgery. 
  • Genetic variants in TNF-α promoter are predictors of recurrence in patients with squamous cell carcinoma of oropharynx after definitive radiotherapy. 
  • Genetic variants in miR-196a2 and miR-499 are associated with susceptibility to esophageal squamous cell carcinoma in Chinese Han population. 
  • Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. 
  • Genetic variants in p53-related genes confer susceptibility to second primary malignancy in patients with index squamous cell carcinoma of head and neck. 
  • Genetic variants in peroxisome proliferator-activated receptor-gamma gene are associated with risk of lung cancer in a Chinese population. 
  • Genetic variants in selected pre-microRNA genes and the risk of squamous cell carcinoma of the head and neck. 
  • Genetic variants in telomerase-related genes are associated with an older age at diagnosis in glioma patients: evidence for distinct pathways of gliomagenesis. 
  • Genetic variants in the H2AFX promoter region are associated with risk of sporadic breast cancer in non-Hispanic white women aged  
  • Genetic variants in the MDM2 promoter and lung cancer risk in a Chinese population. 
  • Genetic variants in the TEP1 gene are associated with prostate cancer risk and recurrence. 
  • Genetic variants in the genes encoding rho GTPases and related regulators predict cutaneous melanoma-specific survival. 
  • Genetic variants in the liver kinase B1-AMP-activated protein kinase pathway genes and pancreatic cancer risk. 
  • Genetic variants in the platelet-derived growth factor subunit B gene associated with pancreatic cancer risk. 
  • Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration. 
  • Genetic variants of GADD45A, GADD45B and MAPK14 predict platinum-based chemotherapy-induced toxicities in Chinese patients with non-small cell lung cancer. 
  • Genetic variants of JNK and p38α pathways and risk of non-small cell lung cancer in an Eastern Chinese population. 
  • Genetic variants of innate immune receptors and infections after liver transplantation. 
  • Genetic variants of p21 and p27 and pancreatic cancer risk in non-Hispanic Whites: a case-control study. 
  • Genetic variants of p27 and p21 as predictors for risk of second primary malignancy in patients with index squamous cell carcinoma of head and neck. 
  • Genetic variants of the ADPRT, XRCC1 and APE1 genes and risk of cutaneous melanoma. 
  • Genetic variants of the LIN28B gene predict severe radiation pneumonitis in patients with non-small cell lung cancer treated with definitive radiation therapy. 
  • Genetic variants of the p53 and p73 genes jointly increase risk of second primary malignancies in patients after index squamous cell carcinoma of the head and neck. 
  • Genetic variants of the vitamin D receptor gene alter risk of cutaneous melanoma. 
  • Genetic variants on chromosome 1q41 influence ocular axial length and high myopia. 
  • Genetic variants primarily associated with type 2 diabetes are related to coronary artery disease risk. 
  • Genetic variation associated with euphorigenic effects of d-amphetamine is associated with diminished risk for schizophrenia and attention deficit hyperactivity disorder. 
  • Genetic variation at a single locus and age of onset for Alzheimer's disease. 
  • Genetic variation in MDM2 and p14ARF and susceptibility to salivary gland carcinoma. 
  • Genetic variation in TYMS in the one-carbon transfer pathway is associated with ovarian carcinoma types in the Ovarian Cancer Association Consortium. 
  • Genetic variation in glutathione S-transferase omega-1, arsenic methyltransferase and methylene-tetrahydrofolate reductase, arsenic exposure and bladder cancer: a case-control study. 
  • Genetic variation in heat shock protein 60 gene and coronary heart disease in China: tagging-SNP haplotype analysis in a case-control study. 
  • Genetic variation in insulin-like growth factor 2 may play a role in ovarian cancer risk. 
  • Genetic variation in nitric oxide synthase 2A (NOS2A) and risk for multiple sclerosis. 
  • Genetic variation in the dectin-1/CARD9 recognition pathway and susceptibility to candidemia. 
  • Genetic variation in the one-carbon transfer pathway and ovarian cancer risk. 
  • Genetic variations in the homologous recombination repair pathway genes modify risk of glioma. 
  • Genetic variations in the mTOR gene contribute toward gastric adenocarcinoma susceptibility in an Eastern Chinese population. 
  • Genetic variations of mTORC1 genes and risk of gastric cancer in an Eastern Chinese population. 
  • Genetic variations of the ADIPOQgene and risk of prostate cancer in Chinese Han men. 
  • Genetic vulnerability to diet-induced obesity in the C57BL/6J mouse: physiological and molecular characteristics. 
  • Genetic/Familial High-Risk Assessment: Breast and Ovarian, Version 2.2015. 
  • Genetic/familial high-risk assessment: breast and ovarian. 
  • Genetic/familial high-risk assessment: breast and ovarian. 
  • Genetically low vitamin D concentrations and myopic refractive error: a Mendelian randomization study. 
  • Genetics and clinical destiny: improving care in hypertrophic cardiomyopathy. 
  • Genetics and the geography of health, behaviour and attainment. 
  • Genetics of childhood steroid-sensitive nephrotic syndrome. 
  • Genetics of coronary heart disease: current knowledge and research principles. 
  • Genetics of coronary heart disease: current understanding and future prospects. 
  • Genetics of exfoliation syndrome and glaucoma. 
  • Genetics of pseudoexfoliation syndrome. 
  • Genetics, genomics, proteomics: what is a cardiologist to do? 
  • Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans. 
  • Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium. 
  • Genome-Wide Association Study to Identify Susceptibility Loci That Modify Radiation-Related Risk for Breast Cancer After Childhood Cancer. 
  • Genome-Wide Association Study with Targeted and Non-targeted NMR Metabolomics Identifies 15 Novel Loci of Urinary Human Metabolic Individuality. 
  • Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types. 
  • Genome-Wide Meta-Analysis of Longitudinal Alcohol Consumption Across Youth and Early Adulthood. 
  • Genome-based pharmacogenetics and the pharmaceutical industry. 
  • Genome-scan for IQ discrepancy in autism: evidence for loci on chromosomes 10 and 16. 
  • Genome-wide Pleiotropy Between Parkinson Disease and Autoimmune Diseases. 
  • Genome-wide analyses of exonic copy number variants in a family-based study point to novel autism susceptibility genes. 
  • Genome-wide analysis of central corneal thickness in primary open-angle glaucoma cases in the NEIGHBOR and GLAUGEN consortia. 
  • Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma. 
  • Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression. 
  • Genome-wide association analyses identify three new susceptibility loci for primary angle closure glaucoma. 
  • Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma. 
  • Genome-wide association analysis identifies a meningioma risk locus at 11p15.5. 
  • Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk. 
  • Genome-wide association analysis identifies six new loci associated with forced vital capacity. 
  • Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations. 
  • Genome-wide association for smoking cessation success: participants in a trial with adjunctive denicotinized cigarettes. 
  • Genome-wide association identifies diverse causes of common variable immunodeficiency. 
  • Genome-wide association meta-analyses to identify common genetic variants associated with hallux valgus in Caucasian and African Americans. 
  • Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error. 
  • Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence. 
  • Genome-wide association of familial prostate cancer cases identifies evidence for a rare segregating haplotype at 8q24.21. 
  • Genome-wide association studies for complex traits: consensus, uncertainty and challenges. 
  • Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans. 
  • Genome-wide association studies identify susceptibility loci for epithelial ovarian cancer in east Asian women. 
  • Genome-wide association studies in Africans and African Americans: expanding the framework of the genomics of human traits and disease. 
  • Genome-wide association studies in Asians confirm the involvement of ATOH7 and TGFBR3, and further identify CARD10 as a novel locus influencing optic disc area. 
  • Genome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference. 
  • Genome-wide association studies of cancer predisposition. 
  • Genome-wide association studies of cancer. 
  • Genome-wide association studies reveal genetic variants in CTNND2 for high myopia in Singapore Chinese. 
  • Genome-wide association study for atopy and allergic rhinitis in a Singapore Chinese population. 
  • Genome-wide association study identifies FCGR2A as a susceptibility locus for Kawasaki disease. 
  • Genome-wide association study identifies HLA 8.1 ancestral haplotype alleles as major genetic risk factors for myositis phenotypes. 
  • Genome-wide association study identifies ZFHX1B as a susceptibility locus for severe myopia. 
  • Genome-wide association study identifies a missense variant at APOA5 for coronary artery disease in Multi-Ethnic Cohorts from Southeast Asia. 
  • Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India. 
  • Genome-wide association study identifies a novel locus for cannabis dependence. 
  • Genome-wide association study identifies a novel susceptibility locus at 6p21.3 among familial CLL. 
  • Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma. 
  • Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia. 
  • Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer. 
  • Genome-wide association study identifies new susceptibility loci for epithelial ovarian cancer in Han Chinese women. 
  • Genome-wide association study identifies nidogen 1 (NID1) as a susceptibility locus to cutaneous nevi and melanoma risk. 
  • Genome-wide association study identifies novel alleles associated with risk of cutaneous basal cell carcinoma and squamous cell carcinoma. 
  • Genome-wide association study identifies novel loci predisposing to cutaneous melanoma. 
  • Genome-wide association study identifies seven novel susceptibility loci for primary open-angle glaucoma. 
  • Genome-wide association study identifies three new melanoma susceptibility loci. 
  • Genome-wide association study identifies three susceptibility loci for laryngeal squamous cell carcinoma in the Chinese population. 
  • Genome-wide association study implicates a chromosome 12 risk locus for late-onset Alzheimer disease. 
  • Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk. 
  • Genome-wide association study in a Chinese population identifies a susceptibility locus for type 2 diabetes at 7q32 near PAX4. 
  • Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci. 
  • Genome-wide association study meta-analysis reveals transethnic replication of mean arterial and pulse pressure loci. 
  • Genome-wide association study of Lp-PLA(2) activity and mass in the Framingham Heart Study. 
  • Genome-wide association study of Parkinson's disease in East Asians. 
  • Genome-wide association study of acute kidney injury after coronary bypass graft surgery identifies susceptibility loci. 
  • Genome-wide association study of bipolar I disorder in the Han Chinese population. 
  • Genome-wide association study of dermatomyositis reveals genetic overlap with other autoimmune disorders. 
  • Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors. 
  • Genome-wide association study of intraocular pressure identifies the GLCCI1/ICA1 region as a glaucoma susceptibility locus. 
  • Genome-wide association study of new-onset atrial fibrillation after coronary artery bypass grafting surgery. 
  • Genome-wide association study of obsessive-compulsive disorder. 
  • Genome-wide association study of posttraumatic stress disorder in a cohort of Iraq-Afghanistan era veterans. 
  • Genome-wide association study of prostate cancer in men of African ancestry identifies a susceptibility locus at 17q21. 
  • Genome-wide association study of severity in multiple sclerosis. 
  • Genome-wide association study of smoking behaviours in patients with COPD. 
  • Genome-wide association study of subtype-specific epithelial ovarian cancer risk alleles using pooled DNA. 
  • Genome-wide association study reveals novel genetic determinants of DNA repair capacity in lung cancer. 
  • Genome-wide gene-environment interaction analysis for asbestos exposure in lung cancer susceptibility. 
  • Genome-wide high-density SNP linkage search for glioma susceptibility loci: results from the Gliogene Consortium. 
  • Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder. 
  • Genome-wide linkage analysis and evidence of gene-by-gene interactions in a sample of 362 multiplex Parkinson disease families. 
  • Genome-wide linkage analysis of 1,233 prostate cancer pedigrees from the International Consortium for Prostate Cancer Genetics using novel sumLINK and sumLOD analyses. 
  • Genome-wide linkage analysis of cardiovascular disease biomarkers in a large, multigenerational family. 
  • Genome-wide linkage scan for prostate cancer aggressiveness loci using families from the University of Michigan Prostate Cancer Genetics Project. 
  • Genome-wide linkage scan for prostate cancer susceptibility from the University of Michigan Prostate Cancer Genetics Project: suggestive evidence for linkage at 16q23. 
  • Genome-wide linkage scan for prostate cancer susceptibility genes in men with aggressive disease: significant evidence for linkage at chromosome 15q12. 
  • Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies. 
  • Genome-wide meta-analyses identifies novel taxane-induced peripheral neuropathy-associated loci. 
  • Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia. 
  • Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. 
  • Genome-wide meta-analysis of cerebral white matter hyperintensities in patients with stroke. 
  • Genome-wide meta-analysis of five Asian cohorts identifies PDGFRA as a susceptibility locus for corneal astigmatism. 
  • Genome-wide meta-analysis of myopia and hyperopia provides evidence for replication of 11 loci. 
  • Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake. 
  • Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. 
  • Genome-wide scan for adult onset primary open angle glaucoma. 
  • Genome-wide scan for prostate cancer susceptibility genes using families from the University of Michigan prostate cancer genetics project finds evidence for linkage on chromosome 17 near BRCA1. 
  • Genome-wide scan of bipolar disorder and investigation of population stratification effects on linkage: support for susceptibility loci at 4q21, 7q36, 9p21, 12q24, 14q24, and 16p13. 
  • Genome-wide scan of copy number variation in late-onset Alzheimer's disease. 
  • Genome-wide significant risk associations for mucinous ovarian carcinoma. 
  • Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. 
  • Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism. 
  • Genomewide association studies of suicide attempts in US soldiers. 
  • Genomewide search for type 2 diabetes susceptibility genes in four American populations. 
  • Genomic Amplifications and Distal 6q Loss: Novel Markers for Poor Survival in High-risk Neuroblastoma Patients. 
  • Genomic Approaches to Posttraumatic Stress Disorder: The Psychiatric Genomic Consortium Initiative. 
  • Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk. 
  • Genomic analyses: a neonatology perspective. 
  • Genomic ancestry and somatic alterations correlate with age at diagnosis in Hispanic children with B-cell acute lymphoblastic leukemia. 
  • Genomic approaches for understanding the genetics of complex disease. 
  • Genomic convergence to identify candidate genes for Parkinson disease: SAGE analysis of the substantia nigra. 
  • Genomic convergence: identifying candidate genes for Parkinson's disease by combining serial analysis of gene expression and genetic linkage. 
  • Genomic correlates of glatiramer acetate adverse cardiovascular effects lead to a novel locus mediating coronary risk. 
  • Genomic landscapes of Chinese sporadic autism spectrum disorders revealed by whole-genome sequencing. 
  • Genomic landscapes of breast fibroepithelial tumors. 
  • Genomic locus modulating corneal thickness in the mouse identifies POU6F2 as a potential risk of developing glaucoma. 
  • Genomic screen and follow-up analysis for autistic disorder. 
  • Genomics and the circulation. 
  • Genomics in the neonatal nursery: Focus on ROP. 
  • Genomics meets HIV-1. 
  • Genomics of Cardiovascular Measures of Autonomic Tone. 
  • Genomics of human health and aging. 
  • Genomics of varicose veins and chronic venous insufficiency. 
  • Genotype-environment interaction in children's adjustment to parental separation. 
  • Genotype-phenotype correlation in ocular von Hippel-Lindau (VHL) disease: the effect of missense mutation position on ocular VHL phenotype. 
  • Genotype-phenotype study in an FSHD family with a proximal deletion encompassing p13E-11 and D4Z4. 
  • Genotypic effect of the -565C>T polymorphism in the ABCA1 gene promoter on ABCA1 expression and severity of atherosclerosis. 
  • Geographical genomics of human leukocyte gene expression variation in southern Morocco. 
  • Germline Genetic IKZF1 Variation and Predisposition to Childhood Acute Lymphoblastic Leukemia. 
  • Germline genetic variants in men with prostate cancer and one or more additional cancers. 
  • Germline genetic variation in ETV6 and risk of childhood acute lymphoblastic leukaemia: a systematic genetic study. 
  • Germline mutations in PPFIBP2 are associated with lethal prostate cancer. 
  • Germline mutations in shelterin complex genes are associated with familial glioma. 
  • Germline rearrangements in families with strong family history of glioma and malignant melanoma, colon, and breast cancer. 
  • Getting biological about the genetics of diabetes. 
  • Glucocerebrosidase gene mutations associated with Parkinson's disease: a meta-analysis in a Chinese population. 
  • Glucose metabolism gene variants modulate the risk of pancreatic cancer. 
  • Glutathione S-transferase M null homozygosity and risk of systemic lupus erythematosus associated with sun exposure: a possible gene-environment interaction for autoimmunity. 
  • Glutathione S-transferase M1, T1, and P1 polymorphisms and ovarian cancer risk: a meta-analysis. 
  • Glutathione S-transferase P1 Ile105Val polymorphism and breast cancer risk: convergence and divergence of the two recent meta-analyses. 
  • Glutathione S-transferase gene polymorphisms and risk and survival of pancreatic cancer. 
  • Glycogen storage disease type IIIa in curly-coated retrievers. 
  • Glycogen storage disease type IV: novel mutations and molecular characterization of a heterogeneous disorder. 
  • Gpr126/Adgrg6 deletion in cartilage models idiopathic scoliosis and pectus excavatum in mice. 
  • Growth of genome screening needs debate. 
  • Guidelines for investigating causality of sequence variants in human disease. 
  • HDAC6 regulates cellular viral RNA sensing by deacetylation of RIG-I. 
  • HDL-cholesterol levels and risk of age-related macular degeneration: a multiethnic genetic study using Mendelian randomization. 
  • HER2 codon 655 polymorphism and risk of breast cancer in African Americans and whites. 
  • HIV heterosexual transmission: a hypothesis about an additional potential determinant. 
  • HIV-1 infection: fooling the gatekeeper. 
  • HIV-associated nephropathy: a case study in race and genetics. 
  • HLA polymorphisms in African Americans with idiopathic inflammatory myopathy: allelic profiles distinguish patients with different clinical phenotypes and myositis autoantibodies. 
  • HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol. 
  • HLA-DM polymorphism and risk of trichloroethylene induced medicamentosa-like dermatitis. 
  • HLA-DQA1 and APOL1 as Risk Loci for Childhood-Onset Steroid-Sensitive and Steroid-Resistant Nephrotic Syndrome. 
  • HLA-DQA1 and PLCG2 Are Candidate Risk Loci for Childhood-Onset Steroid-Sensitive Nephrotic Syndrome. 
  • HLA-DR2 dose effect on susceptibility to multiple sclerosis and influence on disease course. 
  • HOXB13 G84E-related familial prostate cancers: a clinical, histologic, and molecular survey. 
  • HOXB13 and other high penetrant genes for prostate cancer. 
  • HOXB13 is a susceptibility gene for prostate cancer: results from the International Consortium for Prostate Cancer Genetics (ICPCG). 
  • Half of the variation in susceptibility to mortality is genetic: findings from Swedish twin survival data. 
  • Haplotype and genotypes of the VDR gene and cutaneous melanoma risk in non-Hispanic whites in Texas: a case-control study. 
  • Haplotypes spanning the complement factor H gene are protective against age-related macular degeneration. 
  • Health literacy and cancer risk perception: implications for genomic risk communication. 
  • Hearing Loss in Adults. 
  • Hemoglobin C Trait Provides Protection From Clinical Falciparum Malaria in Malian Children. 
  • Hepatitis C and depressive symptoms: psychological and social factors matter more than liver injury. 
  • Hereditary link: scientists seek clues in genetic risks for prostate cancer. 
  • Hereditary ovarian cancer in Ashkenazi Jews. 
  • Hereditary ovarian cancer: recent molecular insights and their impact on screening strategies. 
  • Hereditary prostate cancer in African American families: linkage analysis using markers that map to five candidate susceptibility loci. 
  • Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes. 
  • Heritability of death from coronary heart disease: a 36-year follow-up of 20 966 Swedish twins. 
  • Heterogeneity of toxicant response: sources of human variability. 
  • Heterogeneous association between engrailed-2 and autism in the CPEA network. 
  • Hfe deficiency increases susceptibility to cardiotoxicity and exacerbates changes in iron metabolism induced by doxorubicin. 
  • Hidden heterogeneity in Alzheimer's disease: Insights from genetic association studies and other analyses. 
  • Hierarchy of risk of childhood-onset rheumatoid arthritis conferred by HLA-DRB1 alleles encoding the shared epitope. 
  • High prevalence of rare dopamine receptor D4 alleles in children diagnosed with attention-deficit hyperactivity disorder. 
  • High resolution analysis of genomic aberrations by metaphase and array comparative genomic hybridization identifies candidate tumour genes in lung cancer cell lines. 
  • High stress responsivity predicts later blood pressure only in combination with positive family history and high life stress. 
  • High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4 gene region in autism susceptibility. 
  • High-density single nucleotide polymorphism screen in a large multiplex neural tube defect family refines linkage to loci at 7p21.1-pter and 2q33.1-q35. 
  • High-throughput isolation and mapping of C. elegans mutants susceptible to pathogen infection. 
  • Horizon Scan Of Clinical Laboratories Offering Pharmacogenetic Testing. 
  • Host APOL1 genotype is independently associated with proteinuria in HIV infection. 
  • Host factors for risk and survival in lymphoma. 
  • Host genetics of HIV acquisition and viral control. 
  • Host genetics: fine-tuning innate signaling. 
  • How frailty models can be used for evaluating longevity limits: taking advantage of an interdisciplinary approach. 
  • How heritable is individual susceptibility to death? The results of an analysis of survival data on Danish, Swedish and Finnish twins. 
  • How the effects of aging and stresses of life are integrated in mortality rates: insights for genetic studies of human health and longevity. 
  • Human GFRA1: cloning, mapping, genomic structure, and evaluation as a candidate gene for Hirschsprung disease susceptibility. 
  • Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study. 
  • Human dectin-1 deficiency and mucocutaneous fungal infections. 
  • Human disorders of ubiquitination and proteasomal degradation. 
  • Human genetic susceptibility to Candida infections. 
  • Human genetic variation and yellow fever mortality during 19th century U.S. epidemics. 
  • Human genetics: the hidden text of genome-wide associations. 
  • Human genomics: in search of normality. 
  • Human leukocyte antigen-A, -B, and -DRB1 alleles and sarcoidosis in Chinese Han subjects. 
  • Human leukocyte antigens and drug hypersensitivity. 
  • Hypermethylation of the breast cancer-associated gene 1 promoter does not predict cytologic atypia or correlate with surrogate end points of breast cancer risk. 
  • Hypertension and albuminuria in chronic kidney disease mapped to a mouse chromosome 11 locus. 
  • Hypoglossal neuropathy in hereditary neuropathy with liability to pressure palsy. 
  • Hypothesis-independent pathway analysis implicates GABA and acetyl-CoA metabolism in primary open-angle glaucoma and normal-pressure glaucoma. 
  • IFNL3 mRNA structure is remodeled by a functional non-coding polymorphism associated with hepatitis C virus clearance. 
  • IL-17RC is required for immune signaling via an extended SEF/IL-17R signaling domain in the cytoplasmic tail. 
  • IL1B polymorphism is associated with essential tremor in Chinese population. 
  • IL28B genomic-based treatment paradigms for patients with chronic hepatitis C infection: the future of personalized HCV therapies. 
  • IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production. 
  • IMI - Myopia Genetics Report. 
  • Identification and characterization of novel SNPs in CHEK2 in Ashkenazi Jewish men with prostate cancer. 
  • Identification and functional characterization of JWA polymorphisms and their association with risk of gastric cancer and esophageal squamous cell carcinoma in a Chinese population. 
  • Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31. 
  • Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer. 
  • Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. 
  • Identification of Functional and Expression Polymorphisms Associated With Risk for Antineutrophil Cytoplasmic Autoantibody-Associated Vasculitis. 
  • Identification of a candidate gene for astigmatism. 
  • Identification of a melanoma susceptibility locus and somatic mutation in TET2. 
  • Identification of a novel NBN truncating mutation in a family with hereditary prostate cancer. 
  • Identification of a novel asthma susceptibility gene on chromosome 1qter and its functional evaluation. 
  • Identification of a novel risk variant in the FUS gene in essential tremor. 
  • Identification of a psoriasis susceptibility candidate gene by linkage disequilibrium mapping with a localized single nucleotide polymorphism map. 
  • Identification of a structurally distinct CD101 molecule encoded in the 950-kb Idd10 region of NOD mice. 
  • Identification of genetic polymorphisms associated with risk for pulmonary hypertension in sickle cell disease. 
  • Identification of genetic variants in base excision repair pathway and their associations with risk of esophageal squamous cell carcinoma. 
  • Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus. 
  • Identification of myopia-associated WNT7B polymorphisms provides insights into the mechanism underlying the development of myopia. 
  • Identification of new susceptibility loci for IgA nephropathy in Han Chinese. 
  • Identification of novel genes in late-onset Alzheimer's disease. 
  • Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis. 
  • Identification of novel susceptibility Loci for kawasaki disease in a Han chinese population by a genome-wide association study. 
  • Identification of significant association and gene-gene interaction of GABA receptor subunit genes in autism. 
  • Identification of six new susceptibility loci for invasive epithelial ovarian cancer. 
  • Identification of susceptibility loci contributing to a complex disease using conventional segregation, linkage, and association methods. 
  • Identification of the breast cancer susceptibility gene BRCA2. 
  • Idiopathic pain disorders--pathways of vulnerability. 
  • Imaging genetics. 
  • Immunochip SNP array identifies novel genetic variants conferring susceptibility to candidaemia. 
  • Immunogenetic risk and protective factors for juvenile dermatomyositis in Caucasians. 
  • Immunopathogenesis of juvenile dermatomyositis. 
  • Impact of APOE in mild cognitive impairment. 
  • Impact of Genetic Testing and Family Health History Based Risk Counseling on Behavior Change and Cognitive Precursors for Type 2 Diabetes. 
  • Impact of delivery models on understanding genomic risk for type 2 diabetes. 
  • Impact of direct-to-consumer predictive genomic testing on risk perception and worry among patients receiving routine care in a preventive health clinic. 
  • Impact of gene patents and licensing practices on access to genetic testing for inherited susceptibility to cancer: comparing breast and ovarian cancers with colon cancers. 
  • Impact of race on survival in men with metastatic hormone-refractory prostate cancer. 
  • Impact of self-reported data on the acquisition of multi-generational family history and lifestyle factors among women seen in a high-risk breast screening program: a focus on modifiable risk factors and genetic referral. 
  • In genetic control of disease, does 'race' matter? 
  • In patients with thyroid cancer of follicular cell origin, a family history of nonmedullary thyroid cancer in one first-degree relative is associated with more aggressive disease. 
  • In vitro assays fail to predict in vivo effects of regulatory polymorphisms. 
  • In vitro benzo[a]pyrene diol epoxide-induced DNA damage and chromosomal aberrations in primary lymphocytes, smoking, and risk of squamous cell carcinoma of the head and neck. 
  • In vitro sensitivity to ultraviolet B light and skin cancer risk: a case-control analysis. 
  • In vivo Modeling Implicates APOL1 in Nephropathy: Evidence for Dominant Negative Effects and Epistasis under Anemic Stress. 
  • In vivo differences between endothelial transcriptional profiles of coronary and iliac arteries revealed by microarray analysis. 
  • Inactivation of the tumor suppressor genes causing the hereditary syndromes predisposing to head and neck cancer via promoter hypermethylation in sporadic head and neck cancers. 
  • Incidence and pattern of second primary malignancies in patients with index oropharyngeal cancers versus index nonoropharyngeal head and neck cancers. 
  • Incidence of non-founder BRCA1 and BRCA2 mutations in high risk Ashkenazi breast and ovarian cancer families. 
  • Incorporating ethnicity into genetic risk assessment for Alzheimer disease: the REVEAL study experience. 
  • Incorporating genetic susceptibility feedback into a smoking cessation program for African-American smokers with low income. 
  • Incorporating information regarding preimplantation genetic diagnosis into discussions concerning testing and risk management for BRCA1/2 mutations: a qualitative study of patient preferences. 
  • Incorporating privileged genetic information for fundus image based glaucoma detection. 
  • Increased efficiency of case-control association analysis by using allele-sharing and covariate information. 
  • Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers. 
  • Increased risk of idiopathic chronic pancreatitis in cystic fibrosis carriers. 
  • Increased susceptibility of Trpv4-deficient mice to obesity and obesity-induced osteoarthritis with very high-fat diet. 
  • Indecision. 
  • Independent evidence for an association between general cognitive ability and a genetic locus for educational attainment. 
  • Individual common variants exert weak effects on the risk for autism spectrum disorders. 
  • Inducible nitric oxide synthase (NOS2) promoter CCTTT repeat polymorphism: relationship to in vivo nitric oxide production/NOS activity in an asymptomatic malaria-endemic population. 
  • Inference on haplotype/disease association using parent-affected-child data: the projection conditional on parental haplotypes method. 
  • Inflammation and Immunity Pathways Regulate Genetic Susceptibility to Diabetic Nephropathy. 
  • Inflammation does not predispose to bleeding in hemophilia. 
  • Inflammatory bowel disease susceptibility loci defined by genome scan meta-analysis of 1952 affected relative pairs. 
  • Inflammatory gene polymorphisms and risk of postoperative myocardial infarction after cardiac surgery. 
  • Influence of GRIA1, GRIA2 and GRIA4 polymorphisms on diagnosis and response to antipsychotic treatment in patients with schizophrenia. 
  • Influence of GRIA1, GRIA2 and GRIA4 polymorphisms on diagnosis and response to treatment in patients with major depressive disorder. 
  • Influence of TPH2 variants on diagnosis and response to treatment in patients with major depression, bipolar disorder and schizophrenia. 
  • Influence of genetic background on albuminuria and kidney injury in Ins2(+/C96Y) (Akita) mice. 
  • Influence of genetic risk information on parental role identity in adolescent girls and young women from families with fragile X syndrome. 
  • Influence of interleukin-28B single-nucleotide polymorphisms on progression to liver cirrhosis in human immunodeficiency virus-hepatitis C virus-coinfected patients receiving antiretroviral therapy. 
  • Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. 
  • Influence of obesity-related risk factors in the aetiology of glioma. 
  • Information-seeking and sharing behavior following genomic testing for diabetes risk. 
  • Inherited Predisposition to Prostate Cancer: From Gene Discovery to Clinical Impact. 
  • Inherited determinants of ovarian cancer survival. 
  • Inherited variant on chromosome 11q23 increases susceptibility to IDH-mutated but not IDH-normal gliomas regardless of grade or histology. 
  • Inherited variants in regulatory T cell genes and outcome of ovarian cancer. 
  • Initial Trends in the Use of the 21-Gene Recurrence Score Assay for Patients With Breast Cancer in the Medicare Population, 2005-2009. 
  • Insight in glioma susceptibility through an analysis of 6p22.3, 12p13.33-12.1, 17q22-23.2 and 18q23 SNP genotypes in familial and non-familial glioma. 
  • Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis. 
  • Insulin resistance syndrome and cardiovascular disease: genetics and connections to skeletal muscle function. 
  • Insulin-like growth factor axis gene polymorphisms and clinical outcomes in pancreatic cancer. 
  • Insulin-like growth factor axis gene polymorphisms modify risk of pancreatic cancer. 
  • Insurance reimbursement for risk-reducing mastectomy and oophorectomy in women with BRCA1 or BRCA2 mutations. 
  • Integrated genetic and genomic approach in the SingaporeTranslational and Clinical Research in Psychosis Study: an overview. 
  • Integrated genomic analyses in bronchopulmonary dysplasia. 
  • Integrated pathway and epistasis analysis reveals interactive effect of genetic variants at TERF1 and AFAP1L2 loci on melanoma risk. 
  • Integrating genetic and gene expression evidence into genome-wide association analysis of gene sets. 
  • Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation. 
  • Integrating genetics and social science: genetic risk scores. 
  • Integration of Population-Level Genotype Data with Functional Annotation Reveals Over-Representation of Long Noncoding RNAs at Ovarian Cancer Susceptibility Loci. 
  • Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function. 
  • Integration of molecular diagnostics with therapeutics: implications for drug discovery and patient care. 
  • Integrative analyses reveal signaling pathways underlying familial breast cancer susceptibility. 
  • Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease. 
  • Integrative molecular profiling of routine clinical prostate cancer specimens. 
  • Interaction between the alpha-T catenin gene (VR22) and APOE in Alzheimer's disease. 
  • Interaction of the cytochrome P4501A2, SULT1A1 and NAT gene polymorphisms with smoking and dietary mutagen intake in modification of the risk of pancreatic cancer. 
  • Interactions between genotype and depressive symptoms on obesity. 
  • Interactions between genotype and retrospective ADHD symptoms predict lifetime smoking risk in a sample of young adults. 
  • Interactions of IL-12A and IL-12B polymorphisms on the risk of cervical cancer in Chinese women. 
  • Interest in genetic prostate cancer susceptibility testing among african American men. 
  • Interest in testing for genetic susceptibility to lung cancer among Black college students "at risk" of becoming cigarette smokers. 
  • Intergenerational continuity in parents' and adolescents' externalizing problems: The role of life events and their interaction with GABRA2. 
  • Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis. 
  • Interleukin-1 receptor-associated kinase-1: more evidence. 
  • Interleukin-10 promoter variants predict HPV-positive tumors and survival of squamous cell carcinoma of the oropharynx. 
  • Interleukin-1B gene promoter variants are associated with an increased risk of gastric cancer in a Chinese population. 
  • Interleukin-28B and fibrosing cholestatic hepatitis in posttransplant hepatitis C: a case-control study and literature review. 
  • Interleukin-28B gene polymorphisms do not influence the susceptibility to HIV-infection or CD4 cell decline. 
  • Interpretation of genetic risk feedback among African American smokers with low socioeconomic status. 
  • Interpreting Incidentally Identified Variants in Genes Associated With Catecholaminergic Polymorphic Ventricular Tachycardia in a Large Cohort of Clinical Whole-Exome Genetic Test Referrals. 
  • Interpreting analyses of continuous covariates in affected sibling pair linkage studies. 
  • Interrogation of the platelet-derived growth factor receptor alpha locus and corneal astigmatism in Australians of Northern European ancestry: results of a genome-wide association study. 
  • Interval-timing deficits in individuals at high risk for schizophrenia. 
  • Intrinsic and induced regulation of the age-associated onset of spontaneous experimental autoimmune encephalomyelitis. 
  • Introduction. 
  • Introduction. 
  • Invasion Patterns of Metastatic Extrauterine High-grade Serous Carcinoma With BRCA Germline Mutation and Correlation With Clinical Outcomes. 
  • Investigating the mechanisms of hyporesponse to antiplatelet approaches. 
  • Investigation of known genetic risk factors for primary open angle glaucoma in two populations of African ancestry. 
  • Investigation of potential gene-gene interactions between APOE and RELN contributing to autism risk. 
  • Investigation of seven proposed regions of linkage in multiple sclerosis: an American and French collaborative study. 
  • Investigation of the PARK10 gene in Parkinson disease. 
  • Is our current clinical classification of AMD up to the job? 
  • Is the adiposity-associated FTO gene variant related to all-cause mortality independent of adiposity? Meta-analysis of data from 169,551 Caucasian adults. 
  • Is there a dose-dependent effect of genetic susceptibility loci for gastric cancer on prognosis of the patients? 
  • Is there protective haplotype of dysbindin gene (DTNBP1) 3 polymorphisms for major depressive disorder. 
  • Isogenic normal basal and luminal mammary epithelial isolated by a novel method show a differential response to ionizing radiation. 
  • Joint effect of multiple common SNPs predicts melanoma susceptibility. 
  • K-ras mutation and p16 and preproenkephalin promoter hypermethylation in plasma DNA of pancreatic cancer patients: in relation to cigarette smoking. 
  • Kernel canonical correlation analysis for assessing gene-gene interactions and application to ovarian cancer. 
  • Kidney and eye diseases: common risk factors, etiological mechanisms, and pathways. 
  • Kidney disease in the setting of HIV infection: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. 
  • LIN28B polymorphisms influence susceptibility to epithelial ovarian cancer. 
  • LOC387715/HTRA1 and complement factor H variants in patients with age-related macular degeneration seen at the mayo clinic. 
  • Lack of association between LOXL1 variants and primary open-angle glaucoma in three different populations. 
  • Lack of association between autism and SLC25A12. 
  • Lack of association between primary angle-closure glaucoma susceptibility loci and the ocular biometric parameters anterior chamber depth and axial length. 
  • Lack of support for a role for RLIP76 (RALBP1) in response to treatment or predisposition to epilepsy. 
  • Large candidate gene association study reveals genetic risk factors and therapeutic targets for fibromyalgia. 
  • Large recurrent microdeletions associated with schizophrenia. 
  • Large scale association analysis for identification of genes underlying premature coronary heart disease: cumulative perspective from analysis of 111 candidate genes. 
  • Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets. 
  • Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. 
  • Large-scale association analysis identifies new risk loci for coronary artery disease. 
  • Large-scale evaluation of common variation in regulatory T cell-related genes and ovarian cancer outcome. 
  • Large-scale gene-centric analysis identifies novel variants for coronary artery disease. 
  • Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. 
  • Large-scale pathways-based association study in amyotrophic lateral sclerosis. 
  • Largest GWAS of PTSD (N=20 070) yields genetic overlap with schizophrenia and sex differences in heritability. 
  • Late-onset hereditary axonal neuropathies. 
  • Learning in glaucoma genetic risk assessment. 
  • Leucine-rich repeat kinase 2 deficiency is protective in rhabdomyolysis-induced kidney injury. 
  • Leukemia: an overview for primary care. 
  • Leukocyte telomere length, breast cancer risk in the offspring: the relations with father's age at birth. 
  • Levels of alpha-synuclein mRNA in sporadic Parkinson disease patients. 
  • Levels of cerebrospinal fluid neurofilament light protein in healthy elderly vary as a function of TOMM40 variants. 
  • Leveraging population information in family-based rare variant association analyses of quantitative traits. 
  • Life after the screen: making sense of many P-values. 
  • Life, diversity and the pursuit of haplotypes. 
  • Limited family structure and breast cancer risk. 
  • Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters. 
  • Linkage analysis of 153 prostate cancer families over a 30-cM region containing the putative susceptibility locus HPCX. 
  • Linkage analysis of schizophrenia in African-American families. 
  • Linkage and association with the NOS2A locus on chromosome 17q11 in multiple sclerosis. 
  • Linkage disequilibrium and haplotype tagging polymorphisms in the Tau H1 haplotype. 
  • Lipoprotein receptor-related protein 1 variants and dietary fatty acids: meta-analysis of European origin and African American studies. 
  • Localization of the VHR phosphatase gene and its analysis as a candidate for BRCA1. 
  • Longer genotypically-estimated leukocyte telomere length is associated with increased adult glioma risk. 
  • Longitudinal modeling of cognitive aging and the TOMM40 effect. 
  • Looking beyond the exome: a phenotype-first approach to molecular diagnostic resolution in rare and undiagnosed diseases. 
  • Losing neurons: selective vulnerability and mesial temporal sclerosis. 
  • Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions. 
  • Loss of Function Mutations in NNT Are Associated With Left Ventricular Noncompaction. 
  • Loss of heterozygosity at the mannose 6-phosphate insulin-like growth factor 2 receptor (M6P/IGF2R) locus predisposes patients to radiation-induced lung injury. 
  • Loss of heterozygosity of M6P/IGF2R gene is an early event in the development of prostate cancer. 
  • Loss of heterozygosity of the putative prostate cancer susceptibility gene HPC2/ELAC2 is uncommon in sporadic and familial prostate cancer. 
  • Loss of sirtuin 4 leads to elevated glucose- and leucine-stimulated insulin levels and accelerated age-induced insulin resistance in multiple murine genetic backgrounds. 
  • Loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression. 
  • Loss-of-function mutations in PTPRJ cause a new form of inherited thrombocytopenia. 
  • Low prevalence of myocilin mutations in an African American population with primary open-angle glaucoma. 
  • Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility. 
  • Lower central nervous system serotonergic function and risk of cardiovascular disease: where are we, what's next? 
  • Lumbar lipomyelomeningocele and sacrococcygeal teratoma in siblings: support for an alternative theory of spinal teratoma formation. 
  • M6P/IGF2R loss of heterozygosity in head and neck cancer associated with poor patient prognosis. 
  • MAOA genotype, childhood maltreatment, and their interaction in the etiology of adult antisocial behaviors. 
  • MAOA, maltreatment, and gene-environment interaction predicting children's mental health: new evidence and a meta-analysis. 
  • MCP1 SNPs and pulmonary tuberculosis in cohorts from West Africa, the USA and Argentina: lack of association or epistasis with IL12B polymorphisms. 
  • MDM2 gene promoter polymorphisms and risk of lung cancer: a case-control analysis. 
  • MDM4 genetic variants and risk of gastric cancer in an Eastern Chinese population. 
  • MMP20 and ARMS2/HTRA1 Are Associated with Neovascular Lesion Size in Age-Related Macular Degeneration. 
  • MYH9 and APOL1 are both associated with sickle cell disease nephropathy. 
  • Maintenance Poly (ADP-ribose) Polymerase Inhibitor Therapy for Ovarian Cancer: Precision Oncology or One Size Fits All? 
  • Major LOXL1 risk allele is reversed in exfoliation glaucoma in a black South African population. 
  • Major genetic susceptibility for venous thromboembolism in men: a study of Danish twins. 
  • Major review: Molecular genetics of primary open-angle glaucoma. 
  • Malaria severity: Possible influence of the E670G PCSK9 polymorphism: A preliminary case-control study in Malian children. 
  • Male mice deficient in microsomal epoxide hydrolase are not susceptible to benzene-induced toxicity. 
  • Malignant Mesothelioma in Individuals With Nonmesothelial Neoplasms. 
  • Managing hereditary ovarian cancer risk. 
  • Manganese superoxide dismutase Ala-9Val polymorphism and risk of breast cancer in a population-based case-control study of African Americans and whites. 
  • Mannose-Binding Lectin-Deficient Donors Increase the Risk of Bacterial Infection and Bacterial Infection-Related Mortality After Liver Transplantation. 
  • Mapping autism risk loci using genetic linkage and chromosomal rearrangements. 
  • Mapping genes for NIDDM. Design of the Finland-United States Investigation of NIDDM Genetics (FUSION) Study. 
  • Mapping multiple sclerosis susceptibility to the HLA-DR locus in African Americans. 
  • Mapping of psoriasis to 17q terminus. 
  • Mapping susceptibility genes for bipolar disorder: a pharmacogenetic approach based on excellent response to lithium. 
  • Maternal lineages and Alzheimer disease risk in the Old Order Amish. 
  • Maternal microchimerism in Hirschsprung's disease. 
  • Mathematical modeling: epidemiology meets systems biology. 
  • Matrix metalloproteinase-1 gene promoter polymorphism and risk of ovarian cancer. 
  • Matrix metalloproteinases in premature coronary atherosclerosis: influence of inhibitors, inflammation, and genetic polymorphisms. 
  • Memory self-appraisal in middle-aged and older adults with the apolipoprotein E-4 allele. 
  • Mendelian randomisation study of the relationship between vitamin D and risk of glioma. 
  • MerTK Cleavage on Resident Cardiac Macrophages Compromises Repair After Myocardial Ischemia Reperfusion Injury. 
  • Meta-Analysis of Genome-Wide Association Studies Identifies Genetic Risk Factors for Stroke in African Americans. 
  • Meta-analysis and pooled analysis of GSTM1 and CYP1A1 polymorphisms and oral and pharyngeal cancers: a HuGE-GSEC review. 
  • Meta-analysis identifies common variants associated with body mass index in east Asians. 
  • Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. 
  • Meta-analysis identifies six new susceptibility loci for atrial fibrillation. 
  • Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. 
  • Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia. 
  • Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder. 
  • Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error. 
  • Meta-analysis of genetic polymorphisms in granulomatosis with polyangiitis (Wegener's) reveals shared susceptibility loci with rheumatoid arthritis. 
  • Meta-analysis of genome scans of age-related macular degeneration. 
  • Meta-analysis of genome-wide association studies discovers multiple loci for chronic lymphocytic leukemia. 
  • Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. 
  • Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. 
  • Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index. 
  • Meta-analysis of genome-wide association studies in multiethnic Asians identifies two loci for age-related nuclear cataract. 
  • Methyl parathion: a review of health effects. 
  • Methyl-CpG binding domain 1 gene polymorphisms and lung cancer risk in a Chinese population. 
  • Methylenetetrahydrofolate reductase polymorphisms and risk of squamous cell carcinoma of the head and neck: a case-control analysis. 
  • Methylenetetrahydrofolate reductase polymorphisms/haplotypes and risk of gastric cancer: a case-control analysis in China. 
  • Methylomic analysis of monozygotic twins discordant for childhood psychotic symptoms. 
  • Mice deficient in LRG-47 display increased susceptibility to mycobacterial infection associated with the induction of lymphopenia. 
  • MicroRNA binding-site polymorphisms as potential biomarkers of cancer risk. 
  • MicroRNA genes are frequently located near mouse cancer susceptibility loci. 
  • MicroRNA processing and binding site polymorphisms are not replicated in the Ovarian Cancer Association Consortium. 
  • MicroRNA variants increase the risk of HPV-associated squamous cell carcinoma of the oropharynx in never smokers. 
  • Microarray analysis of multiple candidate genes and associated plasma proteins for nephropathy secondary to type 2 diabetes among Chinese individuals. 
  • Migraine with aura susceptibility locus on chromosome 19p13 is distinct from the familial hemiplegic migraine locus. 
  • Missense mutations in TCF8 cause late-onset Fuchs corneal dystrophy and interact with FCD4 on chromosome 9p. 
  • Missing genetic risk in neural tube defects: can exome sequencing yield an insight? 
  • Mitochondrial DNA sequence variation associated with dementia and cognitive function in the elderly. 
  • Mixed-phenotype large granular lymphocytic leukemia: a rare subtype in the large granular lymphocytic leukemia spectrum. 
  • Modeling genetic risk of breast cancer. 
  • Modulation of the BP response to diet by genes in the renin-angiotensin system and the adrenergic nervous system. 
  • Molecular and functional characterization of novel hypertrophic cardiomyopathy susceptibility mutations in TNNC1-encoded troponin C. 
  • Molecular basis of disease susceptibility in the Texas cytoplasm of maize. 
  • Molecular biologic staging of lung cancer. 
  • Molecular classification of patients with unexplained hamartomatous and hyperplastic polyposis. 
  • Molecular cloning of a novel member of the GLUT family of transporters, SLC2a10 (GLUT10), localized on chromosome 20q13.1: a candidate gene for NIDDM susceptibility. 
  • Molecular cross-talk among chromosome fragility syndromes. 
  • Molecular genetic and family studies in affective disorders: state of the art. 
  • Molecular genetics of nicotine dependence and abstinence: whole genome association using 520,000 SNPs. 
  • Molecular genetics of successful smoking cessation: convergent genome-wide association study results. 
  • Morphologic Features of ALK-negative Anaplastic Large Cell Lymphomas With DUSP22 Rearrangements. 
  • Morphologic correlates of molecular alterations in extrauterine Müllerian carcinomas. 
  • Morphologic patterns associated with BRCA1 and BRCA2 genotype in ovarian carcinoma. 
  • Morphologic variants of familial arrhythmogenic right ventricular dysplasia/cardiomyopathy a genetics-magnetic resonance imaging correlation study. 
  • Morphological, biochemical, and genetic support for an apolipoprotein E effect on microtubular metabolism. 
  • Motivations for genetic testing for lung cancer risk among young smokers. 
  • Motor and non-motor features of Parkinson's disease in LRRK2 G2019S carriers versus matched controls. 
  • Mouse models of retinal ganglion cell death and glaucoma. 
  • Multi-Trait Analysis of GWAS and Biological Insights Into Cognition: A Response to Hill (2018). 
  • Multi-ethnic genome-wide association study for atrial fibrillation. 
  • Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. 
  • Multicenter cohort study on association of genotypes with prospective sports concussion: methods, lessons learned, and recommendations. 
  • Multicentre search for genetic susceptibility loci in sporadic epilepsy syndrome and seizure types: a case-control study. 
  • Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control. 
  • Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. 
  • Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function. 
  • Multifactor dimensionality reduction reveals gene-gene interactions associated with multiple sclerosis susceptibility in African Americans. 
  • Multilocus genetic profile for dopamine signaling predicts ventral striatum reactivity. 
  • Multiple effects of KPQ deletion mutation on gating of human cardiac Na+ channels expressed in mammalian cells. 
  • Multiple genetic variants explain measurable variance in type 2 diabetes-related traits in Pakistanis. 
  • Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer. 
  • Multiple regions within 8q24 independently affect risk for prostate cancer. 
  • Multiple susceptibility loci for multiple sclerosis. 
  • Multiregional Radiogenomic Assessment of Prostate Microenvironments with Multiparametric MR Imaging and DNA Whole-Exome Sequencing of Prostate Glands with Adenocarcinoma. 
  • Multistrain genetic comparisons reveal CCR5 as a receptor involved in airway hyperresponsiveness. 
  • Mutation analysis in Bardet-Biedl syndrome by DNA pooling and massively parallel resequencing in 105 individuals. 
  • Mutation in the mismatch repair gene Msh6 causes cancer susceptibility. 
  • Mutational and susceptibility genetics are different clinical paradigms. 
  • Mutational landscape and clonal architecture in grade II and III gliomas. 
  • Mutational landscape of candidate genes in familial prostate cancer. 
  • Mutations in CIC and FUBP1 contribute to human oligodendroglioma. 
  • Mutations in PLCE1 are a major cause of isolated diffuse mesangial sclerosis (IDMS). 
  • Mutations in SCO2 are associated with autosomal-dominant high-grade myopia. 
  • Mutations in TMEM216 perturb ciliogenesis and cause Joubert, Meckel and related syndromes. 
  • Mutations in a gene encoding a novel protein containing a phosphotyrosine-binding domain cause type 2 cerebral cavernous malformations. 
  • Mutations in the TSGA14 gene in families with autism spectrum disorders. 
  • Mutations in the cilia gene ARL13B lead to the classical form of Joubert syndrome. 
  • Mutations of ANK3 identified by exome sequencing are associated with autism susceptibility. 
  • Myopia genetics: a review of current research and emerging trends. 
  • Myositis in children. 
  • Myotilin is not the causative gene for vocal cord and pharyngeal weakness with distal myopathy (VCPDM). 
  • N-acetyl transferase genotypes in relation to risk of developing systemic lupus erythematosus. 
  • NCAM1 and neurocognition in schizophrenia. 
  • NOS2A and the modulating effect of cigarette smoking in Parkinson's disease. 
  • NOS2A, TLR4, and IFNGR1 interactions influence pulmonary tuberculosis susceptibility in African-Americans. 
  • National Cancer Institute Prostate Cancer Genetics Workshop. 
  • National Heart, Lung, And Blood Institute Clinical Proteomics Working Group report. 
  • Natural History of Drusenoid Pigment Epithelial Detachment Associated with Age-Related Macular Degeneration: Age-Related Eye Disease Study 2 Report No. 17. 
  • Natural and orthogonal model for estimating gene-gene interactions applied to cutaneous melanoma. 
  • Natural genetic variants influencing type 1 diabetes in humans and in the NOD mouse. 
  • Nature X nurture: genetic vulnerabilities interact with physical maltreatment to promote conduct problems. 
  • Neighborhood deprivation affects children's mental health: environmental risks identified in a genetic design. 
  • Neonatal co-infection with helicobacter species markedly accelerates the development of inflammation-associated colonic neoplasia in IL-10(-/-) mice. 
  • Neovascular age-related macular degeneration and its association with LOC387715 and complement factor H polymorphism. 
  • Nephrolithiasis in identical twins: the impact of nature vs nurture. 
  • Nephrotic syndrome in the first year of life: two thirds of cases are caused by mutations in 4 genes (NPHS1, NPHS2, WT1, and LAMB2). 
  • Nested Inversion Polymorphisms Predispose Chromosome 22q11.2 to Meiotic Rearrangements. 
  • Network-Based Integration of GWAS and Gene Expression Identifies a HOX-Centric Network Associated with Serous Ovarian Cancer Risk. 
  • Neural regulation of immunity: role of NPR-1 in pathogen avoidance and regulation of innate immunity. 
  • Neuropathologic features of TOMM40 '523 variant on late-life cognitive decline. 
  • Neuropeptide Y gene polymorphisms confer risk of early-onset atherosclerosis. 
  • Neurotransmission-related genetic polymorphisms, negative affectivity traits, and gender predict tobacco abstinence symptoms across 44 days with and without nicotine patch. 
  • New Genetic Approaches to AD: Lessons from APOE-TOMM40 Phylogenetics. 
  • New developments in proteomics. 
  • New loci and coding variants confer risk for age-related macular degeneration in East Asians. 
  • New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk. 
  • New paradigms in cardiovascular medicine: emerging technologies and practices: perioperative genomics. 
  • New strategies in pancreatic cancer: emerging epidemiologic and therapeutic concepts. 
  • New triggers and non-motor findings in a family with rapid-onset dystonia-parkinsonism. 
  • Newborn screening and the era of medical genomics. 
  • Newborn, carrier, and early childhood screening recommendations for fragile X. 
  • Next-generation computational genetic analysis: multiple complement alleles control survival after Candida albicans infection. 
  • Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error. 
  • Nitric oxide synthase 2 promoter polymorphisms and systemic lupus erythematosus in african-americans. 
  • No Association between hOGG1 Ser326Cys polymorphism and risk of squamous cell carcinoma of the head and neck. 
  • No association between Parkinson disease alleles and the risk of melanoma. 
  • No association between RORA polymorphisms and PTSD in two independent samples. 
  • No association between TGFB1 polymorphisms and late radiotherapy toxicity: a meta-analysis. 
  • No association between the APOE gene and autism. 
  • No association between the MDM2 -309 T/G promoter polymorphism and breast cancer in African-Americans or Whites. 
  • No association of DYNC1H1 with sporadic ALS in a case-control study of a northern European derived population: a tagging SNP approach. 
  • No association of ZNF804A rs1344706 with white matter integrity in schizophrenia: a tract-based spatial statistics study. 
  • No association of the serotonin transporter polymorphisms 5-HTTLPR and RS25531 with schizophrenia or neurocognition. 
  • No evidence for linkage of liability to autism to HOXA1 in a sample from the CPEA network. 
  • No major role of common SV2A variation for predisposition or levetiracetam response in epilepsy. 
  • Non-additive and epistatic effects of HLA polymorphisms contributing to risk of adult glioma. 
  • Nonobese diabetic congenic strain analysis of autoimmune diabetes reveals genetic complexity of the Idd18 locus and identifies Vav3 as a candidate gene. 
  • North American Thrombosis Forum, AF Action Initiative Consensus Document. 
  • Novel CASK mutations in cases with syndromic microcephaly. 
  • Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis. 
  • Novel associations of UDP-glucuronosyltransferase 2B gene variants with prostate cancer risk in a multiethnic study. 
  • Novel compound heterozygous mutations in MYO7A in a Chinese family with Usher syndrome type 1. 
  • Novel congenital myopathy locus identified in Native American Indians at 12q13.13-14.1. 
  • Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. 
  • Novel genetic loci associated with hippocampal volume. 
  • Novel genetic loci underlying human intracranial volume identified through genome-wide association. 
  • Novel genetic variants in the P38MAPK pathway gene ZAK and susceptibility to lung cancer. 
  • Novel late-onset Alzheimer disease loci variants associate with brain gene expression. 
  • Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. 
  • Novel susceptibility gene for nonfamilial hypokalemic periodic paralysis. 
  • Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations. 
  • Novel susceptibility variants at the ERG locus for childhood acute lymphoblastic leukemia in Hispanics. 
  • Novel variants in SPTAN1 without epilepsy: An expansion of the phenotype. 
  • Novelty seeking and the dopamine D4 receptor gene (DRD4) revisited in Asians: haplotype characterization and relevance of the 2-repeat allele. 
  • Nucleotide excision repair core gene polymorphisms and risk of second primary malignancy in patients with index squamous cell carcinoma of the head and neck. 
  • Number of coronary heart disease risk factors and mortality in patients with first myocardial infarction. 
  • Obesity is associated with genetic variants that alter dopamine availability. 
  • Ocular abnormalities in Apert syndrome: genotype/phenotype correlations with fibroblast growth factor receptor type 2 mutations. 
  • On the interplay of telomeres, nevi and the risk of melanoma. 
  • One gene, many neuropsychiatric disorders: lessons from Mendelian diseases. 
  • Open heart surgery and cognitive decline. 
  • Opportunities, resources, and techniques for implementing genomics in clinical care. 
  • Opposing effects of the D70 mutation and the shared epitope in HLA-DR4 on disease activity and certain disease phenotypes in rheumatoid arthritis. 
  • Ordered subset analysis for case-control studies. 
  • Ordered subset analysis in genetic linkage mapping of complex traits. 
  • Ordered subset linkage analysis supports a susceptibility locus for age-related macular degeneration on chromosome 16p12. 
  • Ordered-subset analysis (OSA) for family-based association mapping of complex traits. 
  • Organizing the fluid membrane bilayer: diseases linked to spectrin and ankyrin. 
  • Origins of depression in later life. 
  • Orion: Detecting regions of the human non-coding genome that are intolerant to variation using population genetics. 
  • Outcome of Whole Exome Sequencing for Diagnostic Odyssey Cases of an Individualized Medicine Clinic: The Mayo Clinic Experience. 
  • Outcome of transplantation for acute lymphoblastic leukemia in children with Down syndrome. 
  • Ovarian cancer risk associated with inherited inflammation-related variants. 
  • Ovarian cancer risk in Ashkenazi Jewish carriers of BRCA1 and BRCA2 mutations. 
  • Ovarian cancer risk, ALDH2 polymorphism and alcohol drinking: Asian data from the Ovarian Cancer Association Consortium. 
  • Ovarian carcinoma screening in women at intermediate risk: impact on quality of life and need for invasive follow-up. 
  • Overexpression of the cardiac beta(2)-adrenergic receptor and expression of a beta-adrenergic receptor kinase-1 (betaARK1) inhibitor both increase myocardial contractility but have differential effects on susceptibility to ischemic injury. 
  • Ozone-induced acute pulmonary injury in inbred mouse strains. 
  • P53 codon 72 polymorphism and risk of gastric cancer in a Chinese population. 
  • PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS. 
  • PDE7B, NMBR and EPM2A Variants and Schizophrenia: A Case-Control and Pharmacogenetics Study. 
  • PGC-1 coactivators regulate MITF and the tanning response. 
  • PLN-encoded phospholamban mutation in a large cohort of hypertrophic cardiomyopathy cases: summary of the literature and implications for genetic testing. 
  • PMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance. 
  • PSCA polymorphisms and gastric cancer susceptibility in an eastern Chinese population. 
  • PSORS2 is due to mutations in CARD14. 
  • Pain perception is altered by a nucleotide polymorphism in SCN9A. 
  • Pancreatic adenocarcinoma: Clinical Practice Guidelines in Oncology. 
  • Parental education and late-life dementia in the United States. 
  • Parental intermittent claudication as risk factor for claudication in adults. 
  • Parents' attitudes toward pediatric genetic testing for common disease risk. 
  • Parkin mutations and susceptibility alleles in late-onset Parkinson's disease. 
  • Parkin-proven disease: common founders but divergent phenotypes. 
  • Parsing the genetic heterogeneity of chromosome 12q susceptibility genes for Alzheimer disease by family-based association analysis. 
  • Pathogen-specific loss of host resistance in mice lacking the IFN-gamma-inducible gene IGTP. 
  • Pathogenesis and therapy of focal segmental glomerulosclerosis: an update. 
  • Pathogenesis and treatment of HIV-associated renal diseases: lessons from clinical and animal studies, molecular pathologic correlations, and genetic investigations. 
  • Pathogenesis of varicose veins. 
  • Pathogenic Germline Variants in 10,389 Adult Cancers. 
  • Pathologic and molecular features correlate with long-term outcome after adjuvant therapy of resected primary GI stromal tumor: the ACOSOG Z9001 trial. 
  • Pathologic findings at risk-reducing salpingo-oophorectomy: primary results from Gynecologic Oncology Group Trial GOG-0199. 
  • Pathophysiology of SPINK mutations in pancreatic development and disease. 
  • Pathway-analysis of published genome-wide association studies of lung cancer: A potential role for the CYP4F3 locus. 
  • Pathway-based identification of SNPs predictive of survival. 
  • Patient and primary care provider experience using a family health history collection, risk stratification, and clinical decision support tool: a type 2 hybrid controlled implementation-effectiveness trial. 
  • Patient beliefs and behaviors about genomic risk for type 2 diabetes: implications for prevention. 
  • Peakwide mapping on chromosome 3q13 identifies the kalirin gene as a novel candidate gene for coronary artery disease. 
  • Pediatric obesity: the unique issues in Latino-American male youth. 
  • Pelvic Inflammatory Disease and the Risk of Ovarian Cancer and Borderline Ovarian Tumors: A Pooled Analysis of 13 Case-Control Studies. 
  • PenPC: A two-step approach to estimate the skeletons of high-dimensional directed acyclic graphs. 
  • Persistent infection with neurotropic herpes viruses and cognitive impairment. 
  • Personalized medicine and human genetic diversity. 
  • Personalized medicine: progress and promise. 
  • Personalized targeted therapy for esophageal squamous cell carcinoma. 
  • Perspective: Prospective health care and the role of academic medicine: lead, follow, or get out of the way. 
  • Pharmacogenetic Discovery in CALGB (Alliance) 90401 and Mechanistic Validation of a VAC14 Polymorphism that Increases Risk of Docetaxel-Induced Neuropathy. 
  • Pharmacogenetic predictors of statin-mediated low-density lipoprotein cholesterol reduction and dose response. 
  • Pharmacogenetic testing: not as simple as it seems. 
  • Pharmacogenetics and pharmacogenomics in the discovery and development of medicines. 
  • Pharmacogenetics of toxic epidermal necrolysis. 
  • Pharmacologic approaches to the prevention of type 2 diabetes in high risk pediatric patients. 
  • Phenome-wide association studies (PheWASs) for functional variants. 
  • Phenotypic homogeneity provides increased support for linkage on chromosome 2 in autistic disorder. 
  • Phenotyping clinical disorders: lessons learned from pelvic organ prolapse. 
  • PhyloOncology: Understanding cancer through phylogenetic analysis. 
  • Pioneering geneticist Mary-Claire King receives the 2014 Lasker~Koshland Special Achievement Award in Medical Science. 
  • Plasma Levels of Soluble Interleukin-2 Receptor α: Associations With Clinical Cardiovascular Events and Genome-Wide Association Scan. 
  • Plasminogen alleles influence susceptibility to invasive aspergillosis. 
  • Plasmodium vivax Infections over 3 Years in Duffy Blood Group Negative Malians in Bandiagara, Mali. 
  • Platelet PlA2 polymorphism and thromboembolic events: from inherited risk to pharmacogenetics. 
  • Pleiotropic Associations of Allelic Variants in a 2q22 Region with Risks of Major Human Diseases and Mortality. 
  • Podocyte-specific knockout of cyclooxygenase 2 exacerbates diabetic kidney disease. 
  • Polygenic Risk, Appetite Traits, and Weight Gain in Middle Childhood: A Longitudinal Study. 
  • Polygenic effects of common single-nucleotide polymorphisms on life span: when association meets causality. 
  • Polygenic loading for major depression is associated with specific medical comorbidity. 
  • Polygenic risk for schizophrenia and measured domains of cognition in individuals with psychosis and controls. 
  • Polygenic risk score, genome-wide association, and gene set analyses of cognitive domain deficits in schizophrenia. 
  • Polygenic risk, rapid childhood growth, and the development of obesity: evidence from a 4-decade longitudinal study. 
  • Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders. 
  • Polymorphic hCHK2/hCds1 codon 84 allele and risk of squamous cell carcinoma of the head and neck--a case-control analysis. 
  • Polymorphism in the GALNT1 gene and epithelial ovarian cancer in non-Hispanic white women: the Ovarian Cancer Association Consortium. 
  • Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women. 
  • Polymorphism in the TOMM40 gene modifies the risk of developing sporadic inclusion body myositis and the age of onset of symptoms. 
  • Polymorphism of DNA ligase I and risk of lung cancer--a case-control analysis. 
  • Polymorphisms and haplotypes of the NBS1 gene are associated with risk of sporadic breast cancer in non-Hispanic white women  
  • Polymorphisms at the microRNA binding-site of the stem cell marker gene CD133 modify susceptibility to and survival of gastric cancer. 
  • Polymorphisms identified through genome-wide association studies and their associations with type 2 diabetes in Chinese, Malays, and Asian-Indians in Singapore. 
  • Polymorphisms in DNA base excision repair genes ADPRT and XRCC1 and risk of lung cancer. 
  • Polymorphisms in DNA damage binding protein 2 (DDB2) and susceptibility of primary lung cancer in the Chinese: a case-control study. 
  • Polymorphisms in HLA Class II Genes Are Associated With Susceptibility to Staphylococcus aureus Infection in a White Population. 
  • Polymorphisms in NF-kappaB inhibitors and risk of epithelial ovarian cancer. 
  • Polymorphisms in TCEAL7 and risk of epithelial ovarian cancer. 
  • Polymorphisms in adenosine receptor genes are associated with infarct size in patients with ischemic cardiomyopathy. 
  • Polymorphisms in excision repair cross-complementing group 4 (ERCC4) and susceptibility to primary lung cancer in a Chinese Han population. 
  • Polymorphisms in hMLH1 and risk of early-onset lung cancer in a southeast Chinese population. 
  • Polymorphisms in nucleotide excision repair genes and risk of primary prostate cancer in Chinese Han populations. 
  • Polymorphisms in stromal genes and susceptibility to serous epithelial ovarian cancer: a report from the Ovarian Cancer Association Consortium. 
  • Polymorphisms in the ACE and ADRB2 genes and risks of aging-associated phenotypes: the case of myocardial infarction. 
  • Polymorphisms in the MDM2 promoter and risk of breast cancer: a case-control analysis in a Chinese population. 
  • Polymorphisms in the XPG gene and risk of gastric cancer in Chinese populations. 
  • Polymorphisms in the glucocorticoid receptor co-chaperone FKBP5 predict persistent musculoskeletal pain after traumatic stress exposure. 
  • Polymorphisms in the kinesin-like factor 1 B gene and risk of epithelial ovarian cancer in Eastern Chinese women. 
  • Polymorphisms in the mTOR gene and risk of sporadic prostate cancer in an Eastern Chinese population. 
  • Polymorphisms in the prostate-specific antigen gene promoter do not predict serum prostate-specific antigen levels in African-American men. 
  • Polymorphisms in the two helicases ERCC2/XPD and ERCC3/XPB of the transcription factor IIH complex and risk of lung cancer: a case-control analysis in a Chinese population. 
  • Polymorphisms in thymidylate synthase gene and susceptibility to breast cancer in a Chinese population: a case-control analysis. 
  • Polymorphisms of CAK genes and risk for lung cancer: a case-control study in Chinese population. 
  • Polymorphisms of DNA repair gene XRCC1 in squamous cell carcinoma of the head and neck. 
  • Polymorphisms of DNA repair gene XRCC3 Thr241Met and risk of gastric cancer in a Chinese population. 
  • Polymorphisms of FAS and FAS ligand genes involved in the death pathway and risk and progression of squamous cell carcinoma of the head and neck. 
  • Polymorphisms of cytochrome P4501A2 and N-acetyltransferase genes, smoking, and risk of pancreatic cancer. 
  • Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load. 
  • Polymorphisms of the DNA repair gene MGMT and risk and progression of head and neck cancer. 
  • Polymorphisms of the DNA repair gene XPD and risk of lung cancer in a Chinese population. 
  • Polymorphisms of the DNMT3B gene and risk of squamous cell carcinoma of the head and neck: a case-control study. 
  • Polymorphisms of the Interleukin 6 gene contribute to cervical cancer susceptibility in Eastern Chinese women. 
  • Polymorphisms of the centrosomal gene (FGFR1OP) and lung cancer risk: a meta-analysis of 14,463 cases and 44,188 controls. 
  • Polymorphisms of the neuronal and inducible nitric oxide synthase genes and the risk of cutaneous melanoma: a case-control study. 
  • Polypoidal choroidal vasculopathy and neovascular age-related macular degeneration: same or different disease? 
  • Population genomics in South East Asia captures unexpectedly high carrier frequency for treatable inherited disorders. 
  • Possible association between genetic variants in the H2AFX promoter region and risk of adult glioma in a Chinese Han population. 
  • Possible influence of CREB1, CREBBP and CREM variants on diagnosis and treatment outcome in patients with schizophrenia. 
  • Posttraumatic stress associated with cancer history and BRCA1/2 genetic testing. 
  • Potential misinterpretation of the case-only study to assess gene-environment interaction. 
  • Potentially Functional Variants of ATG16L2 Predict Radiation Pneumonitis and Outcomes in Patients with Non-Small Cell Lung Cancer after Definitive Radiotherapy. 
  • Potentially functional genetic variants in the TNF/TNFR signaling pathway genes predict survival of patients with non-small cell lung cancer in the PLCO cancer screening trial. 
  • Potentially functional polymorphisms in the CASP7 gene contribute to gastric adenocarcinoma susceptibility in an eastern Chinese population. 
  • Potentially functional polymorphisms in the ERCC2 gene and risk of esophageal squamous cell carcinoma in Chinese populations. 
  • Potentially functional polymorphisms of EXO1 and risk of lung cancer in a Chinese population: A case-control analysis. 
  • Potentially functional single nucleotide polymorphisms in the core nucleotide excision repair genes and risk of squamous cell carcinoma of the head and neck. 
  • Potentially functional variants in the core nucleotide excision repair genes predict survival in Japanese gastric cancer patients. 
  • Potentially functional variants of PLCE1 identified by GWASs contribute to gastric adenocarcinoma susceptibility in an eastern Chinese population. 
  • Power and sample size calculations for SNP association studies with censored time-to-event outcomes. 
  • Practice and public policy in the era of gene-environment interactions. 
  • Pre-counseling education materials for BRCA testing: does tailoring make a difference? 
  • Pre-miRNA variants as predictors of clinical outcome in patients with squamous cell carcinomas of the nonoropharynx. 
  • Precocious osteoarthritis in a family with recurrent COL2A1 mutation. 
  • Prefrontal activation patterns in subjects at risk for Alzheimer disease. 
  • Preliminary report of a genetic basis for cognitive decline after cardiac operations. The Neurologic Outcome Research Group of the Duke Heart Center. 
  • Preliminary report of a genetic basis for cognitive decline after cardiac operations. The Neurologic Outcome Research Group of the Duke Heart Center. 
  • Preliminary report on the interaction of apolipoprotein E polymorphism with aortic atherosclerosis and acute nephropathy after CABG. 
  • Premature myocardial infarction novel susceptibility locus on chromosome 1P34-36 identified by genomewide linkage analysis. 
  • Prenatal smoking and early childhood conduct problems: testing genetic and environmental explanations of the association. 
  • Preterm birth, long-term survival, and fertility. 
  • Prevalence and correlates of vitamin and supplement usage among men with a family history of prostate cancer. 
  • Prevalence of BRCA mutations among women with triple-negative breast cancer (TNBC) in a genetic counseling cohort. 
  • Prevalence of BRCA1 and BRCA2 mutations in Ashkenazi Jewish families with breast and pancreatic cancer. 
  • Prevalence of deleterious ATM germline mutations in gastric cancer patients. 
  • Prevalence of factor V G1691A (Leiden), prothrombin G20210A, and methylene tetrahydrofolate reductase C677T thrombophilic mutations in children with inflammatory bowel disease. 
  • Prevalence of the HOXB13 G84E prostate cancer risk allele in men treated with radical prostatectomy. 
  • Prevention and Control of Hypertension: JACC Health Promotion Series. 
  • Pri-miR-124 rs531564 and pri-miR-34b/c rs4938723 polymorphisms are associated with decreased risk of esophageal squamous cell carcinoma in Chinese populations. 
  • Primary prevention of ischemic stroke: A statement for healthcare professionals from the Stroke Council of the American Heart Association. 
  • Primary prevention of ischemic stroke: A statement for healthcare professionals from the Stroke Council of the American Heart Association. 
  • Principal components of heritability from neurocognitive domains differ between families with schizophrenia and control subjects. 
  • Prioritizing genetic variants for causality on the basis of preferential linkage disequilibrium. 
  • Privacy, families, and human subject protections: some lessons from pedigree research. 
  • Probing the role of PPARγ in the regulation of late-onset Alzheimer's disease-associated genes. 
  • Problems meeting basic needs moderate the association between the APOE epsilon4 allele and cognitive decline. 
  • Proceedings of the fifth international RASopathies symposium: When development and cancer intersect. 
  • Progesterone receptor gene polymorphisms and risk of endometriosis: results from an international collaborative effort. 
  • Progesterone receptor variation and risk of ovarian cancer is limited to the invasive endometrioid subtype: results from the Ovarian Cancer Association Consortium pooled analysis. 
  • Prohibitin mutations are uncommon in prostate cancer families linked to chromosome 17q. 
  • Promoter polymorphisms in matrix metallopeptidase 1 and risk of cutaneous melanoma. 
  • Promotion by sodium barbital induces early development but does not increase the multiplicity of hereditary renal tumors in Eker rats. 
  • Prospective Evaluation of Germline Alterations in Patients With Exocrine Pancreatic Neoplasms. 
  • Prospective analysis of DNA damage and repair markers of lung cancer risk from the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial. 
  • Prospective associations of coronary heart disease loci in African Americans using the MetaboChip: the PAGE study. 
  • Prospects for personalized cardiovascular medicine: the impact of genomics. 
  • Prostate cancer susceptibility polymorphism rs2660753 is not associated with invasive ovarian cancer. 
  • Protective effect of complement factor B and complement component 2 variants in age-related macular degeneration. 
  • Protective role of the apolipoprotein E2 allele in age-related disease traits and survival: evidence from the Long Life Family Study. 
  • Protocol for the "Implementation, adoption, and utility of family history in diverse care settings" study. 
  • Pseudoexfoliation syndrome in Icelandic families. 
  • Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways. 
  • Public knowledge of and attitudes toward genetics and genetic testing. 
  • Pulmonary fibrosis: patterns and perpetrators. 
  • Pulmonary fibrosis: thinking outside of the lung. 
  • Putative digenic inheritance of heterozygous RP1L1 and C2orf71 null mutations in syndromic retinal dystrophy. 
  • Putatively functional PLCE1 variants and susceptibility to esophageal squamous cell carcinoma (ESCC): a case-control study in eastern Chinese populations. 
  • Puzzling role of genetic risk factors in human longevity: "risk alleles" as pro-longevity variants. 
  • QTL mapping in a mouse model of cardiomyopathy reveals an ancestral modifier allele affecting heart function and survival. 
  • Quantitative genetic analysis of the retinal vascular caliber: the Australian Twins Eye Study. 
  • Quantitative linkage genome scan for atopy in a large collection of Caucasian families. 
  • Quinone oxidoreductase (NQO1) gene polymorphism may not confer a susceptibility to mood disorders. 
  • R726L androgen receptor mutation is uncommon in prostate cancer families in the united states. 
  • RET polymorphisms and haplotypes and risk of differentiated thyroid cancer. 
  • REV3L 3'UTR 460 T>C polymorphism in microRNA target sites contributes to lung cancer susceptibility. 
  • RUNX1 mutations are associated with poor outcome in younger and older patients with cytogenetically normal acute myeloid leukemia and with distinct gene and MicroRNA expression signatures. 
  • Race-associated biological differences among luminal A and basal-like breast cancers in the Carolina Breast Cancer Study. 
  • Racial and Ethnic Disparities in Health and Health Care. 
  • Racial differences in prostate cancer screening by family history. 
  • Racial differences of lipoprotein subclass distributions in postmenopausal women. 
  • Radiogenomic analysis of breast cancer: luminal B molecular subtype is associated with enhancement dynamics at MR imaging. 
  • Radiogenomics: what it is and why it is important. 
  • Radiographic severity of knee osteoarthritis is conditional on interleukin 1 receptor antagonist gene variations. 
  • Rare BRCA1 haplotypes including 3'UTR SNPs associated with breast cancer risk. 
  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. 
  • Rare de novo germline copy-number variation in testicular cancer. 
  • Rare variants create synthetic genome-wide associations. 
  • Rare variants in CFI, C3 and C9 are associated with high risk of advanced age-related macular degeneration. 
  • Rare, low frequency and common coding variants in CHRNA5 and their contribution to nicotine dependence in European and African Americans. 
  • Recent advances in research on early detection, causes, biology, and treatment of autism spectrum disorders. 
  • Recent progress in HIV-associated nephropathy. 
  • Recommendations for national and local regulatory authorities concerning research in genetic markers of disease. 
  • Rectal cancer. 
  • Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis. 
  • Recurrence risks for neural tube defects in siblings of patients with lipomyelomeningocele. 
  • Recurrent spontaneous abortion and skewed X-inactivation: is there an association? 
  • Reduced DNA repair capacity for removing tobacco carcinogen-induced DNA adducts contributes to risk of head and neck cancer but not tumor characteristics. 
  • Reduced DNA repair of benzo[a]pyrene diol epoxide-induced adducts and common XPD polymorphisms in breast cancer patients. 
  • Reduced mRNA expression of nucleotide excision repair genes in lymphocytes and risk of squamous cell carcinoma of the head and neck. 
  • Refinement of 2q and 7p loci in a large multiplex NTD family. 
  • Refinement of the PARK3 locus on chromosome 2p13 and the analysis of 14 candidate genes. 
  • Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes. 
  • Regarding "The Munich vulnerability study on affective disorders: premorbid polysomnographic profile of affected high-risk probands". 
  • Regional differences in awareness and attitudes regarding genetic testing for disease risk and ancestry. 
  • Regulatory crosstalk between lineage-survival oncogenes KLF5, GATA4 and GATA6 cooperatively promotes gastric cancer development. 
  • Relationship between CYP2A6 and CHRNA5-CHRNA3-CHRNB4 variation and smoking behaviors and lung cancer risk. 
  • Relationships among breast cancer concern, risk perceptions, and interest in genetic testing for breast cancer susceptibility among African-American women with and without a family history of breast cancer. 
  • Relative Contribution of Risk Factors for Early-Onset Myopia in Young Asian Children. 
  • Renovascular disease is associated with low producer genotypes of the anti-inflammatory cytokine interleukin-10. 
  • Repair of UV light-induced DNA damage and risk of cutaneous malignant melanoma. 
  • Repair of mitomycin C cross-linked DNA in mammalian cells measured by a host cell reactivation assay. 
  • Replication and meta-analysis of GWAS identified susceptibility loci in Kawasaki disease confirm the importance of B lymphoid tyrosine kinase (BLK) in disease susceptibility. 
  • Replication of TCF4 through association and linkage studies in late-onset Fuchs endothelial corneal dystrophy. 
  • Replication of genome-wide association signals of type 2 diabetes in Han Chinese in a prospective cohort. 
  • Replication of the recessive STBMS1 locus but with dominant inheritance. 
  • Replication study of the insulin receptor gene in migraine with aura. 
  • Report from Durham. 
  • Reproductive factors and familial predisposition for breast cancer by age 50 years. A case-control-family study for assessing main effects and possible gene-environment interaction. 
  • Reproductive factors in relation to breast cancer characterized by p53 protein expression (United States). 
  • Resistance to cerebral ischemic injury in UCP2 knockout mice: evidence for a role of UCP2 as a regulator of mitochondrial glutathione levels. 
  • Resolving multiple epigenetic pathways to adolescent depression. 
  • Response to commentary on the multimodal treatment study of ADHD (MTA): mining the meaning of the MTA. 
  • Responses to online GSTM1 genetic test results among smokers related to patients with lung cancer: a pilot study. 
  • Resting-state brain function in schizophrenia and psychotic bipolar probands and their first-degree relatives. 
  • Retinal vascular caliber: systemic, environmental, and genetic associations. 
  • Revealing the role of glutathione S-transferase omega in age-at-onset of Alzheimer and Parkinson diseases. 
  • Reversible nitrous oxide myelopathy and a polymorphism in the gene encoding 5,10-methylenetetrahydrofolate reductase. 
  • Revisiting the association between reading achievement and antisocial behavior: new evidence of an environmental explanation from a twin study. 
  • Right amygdala volume in adolescent and young adult offspring from families at high risk for developing alcoholism. 
  • Risk Analysis of Prostate Cancer in PRACTICAL, a Multinational Consortium, Using 25 Known Prostate Cancer Susceptibility Loci. 
  • Risk Prediction for Epithelial Ovarian Cancer in 11 United States-Based Case-Control Studies: Incorporation of Epidemiologic Risk Factors and 17 Confirmed Genetic Loci. 
  • Risk alleles for multiple sclerosis identified by a genomewide study. 
  • Risk factors for head and neck cancer in young adults: a pooled analysis in the INHANCE consortium. 
  • Risk factors for ovarian cancers with and without microsatellite instability. 
  • Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis. 
  • Risk of Alzheimer disease with the epsilon4 allele for apolipoprotein E in a population-based study of men aged 62-73 years. 
  • Risk of ovarian cancer and inherited variants in relapse-associated genes. 
  • Risk of ovarian cancer in BRCA1 and BRCA2 mutation-negative hereditary breast cancer families. 
  • Risk prediction of prevalent diabetes in a Swiss population using a weighted genetic score--the CoLaus Study. 
  • Risk stratification in arrhythmogenic right ventricular dysplasia/cardiomyopathy-associated desmosomal mutation carriers. 
  • Risk-benefit assessment of the combined oral contraceptive pill in women with a family history of female cancer. 
  • Robust testing of haplotype/disease association. 
  • Role of GABRA2 in trajectories of externalizing behavior across development and evidence of moderation by parental monitoring. 
  • Role of Genetic Testing for Inherited Prostate Cancer Risk: Philadelphia Prostate Cancer Consensus Conference 2017. 
  • Role of HFE gene mutations in liver diseases other than hereditary hemochromatosis. 
  • Role of autophagy genetic variants for the risk of Candida infections. 
  • Role of common genetic variants in ovarian cancer susceptibility and outcome: progress to date from the Ovarian Cancer Association Consortium (OCAC). 
  • Role of genetic polymorphisms and ovarian cancer susceptibility. 
  • Role of genetic polymorphisms in ovarian cancer susceptibility: development of an international ovarian cancer association consortium. 
  • Role of human leukocyte antigen class I alleles in progressive multifocal leukoencephalopathy. 
  • Role of mitofusin 2 mutations in the physiopathology of Charcot-Marie-Tooth disease type 2A. 
  • Role of the Nijmegen breakage syndrome 1 gene in familial and sporadic prostate cancer. 
  • Roles of genetic variants in the PI3K and RAS/RAF pathways in susceptibility to endometrial cancer and clinical outcomes. 
  • SCN5A variant that blocks fibroblast growth factor homologous factor regulation causes human arrhythmia. 
  • SMCHD1 mutations associated with a rare muscular dystrophy can also cause isolated arhinia and Bosma arhinia microphthalmia syndrome. 
  • SNPing away at complex diseases: analysis of single-nucleotide polymorphisms around APOE in Alzheimer disease. 
  • SNPs in Multi-species Conserved Sequences (MCS) as useful markers in association studies: a practical approach. 
  • SNPselector: a web tool for selecting SNPs for genetic association studies. 
  • Schizophrenia genetics comes of age. 
  • Schizophrenia polygenic risk score predicts mnemonic hippocampal activity. 
  • Schizophrenia: From genetics to physiology at last. 
  • Screening and prevention of hereditary gynecologic cancers. 
  • Screening for familial and hereditary prostate cancer. 
  • Screening for familial ovarian cancer: a ray of hope and a light to steer by. 
  • Screening for prostate cancer in high risk populations. 
  • Screening for the breast cancer gene (BRCA1) using a biochip system and molecular beacon probes immobilized on solid surfaces. 
  • Screening the genome for rheumatoid arthritis susceptibility genes: a replication study and combined analysis of 512 multicase families. 
  • Screening, early detection, and diagnosis of pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines. 
  • Search for genes involved in Joubert syndrome: evidence that one or more major loci are yet to be identified and exclusion of candidate genes EN1, EN2, FGF8, and BARHL1. 
  • Searching for genes that matter in acute kidney injury: a systematic review. 
  • Secrets of the perioptome: new tools for a new concept. 
  • Seizure predisposition after perinatal hypoxia: effects of subsequent age and of an epilepsy predisposing gene mutation. 
  • Select high-risk genetic features predict earlier progression following chemoimmunotherapy with fludarabine and rituximab in chronic lymphocytic leukemia: justification for risk-adapted therapy. 
  • Selected polymorphisms of DNA repair genes and risk of pancreatic cancer. 
  • Self-reported family history of leiomyoma: not a reliable marker of high risk. 
  • Sensitivity to DNA damage induced by benzo(a)pyrene diol epoxide and risk of lung cancer: a case-control analysis. 
  • Sensitivity to benzo(a)pyrene diol-epoxide associated with risk of breast cancer in young women and modulation by glutathione S-transferase polymorphisms: a case-control study. 
  • Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction. 
  • Sequence variation in alpha-methylacyl-CoA racemase and risk of early-onset and familial prostate cancer. 
  • Sequence variation in the mitochondrial gene cytochrome c oxidase subunit I and prostate cancer in African American men. 
  • Sequence variation in the transforming growth factor-beta1 (TGFB1) gene and multiple sclerosis susceptibility. 
  • Sequencing studies in human genetics: design and interpretation. 
  • Serotonin transporter gene moderates the development of emotional problems among children following bullying victimization. 
  • Serotonin transporter-linked polymorphic region (5-HTTLPR) genotype and stressful life events interact to predict preschool-onset depression: a replication and developmental extension. 
  • Serum microRNA profiling and breast cancer risk: the use of miR-484/191 as endogenous controls. 
  • Seven new loci associated with age-related macular degeneration. 
  • Sex-specific differences in the predictive value of cholesterol homeostasis markers and 10-year cardiovascular disease event rate in Framingham Offspring Study participants. 
  • Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21. 
  • Shared and restricted T-cell receptor use is crucial for carbamazepine-induced Stevens-Johnson syndrome. 
  • Shared genetic variants for polypoidal choroidal vasculopathy and typical neovascular age-related macular degeneration in East Asians. 
  • Shared genetics underlying epidemiological association between endometriosis and ovarian cancer. 
  • Shared heritability and functional enrichment across six solid cancers. 
  • Short/long heterozygotes at 5HTTLPR and white matter lesions in geriatric depression. 
  • Shortened telomere length is associated with increased risk of cancer: a meta-analysis. 
  • Sickle cell disease and H3Africa: enhancing genomic research on cardiovascular diseases in African patients. 
  • Significance of MDM2 and P14 ARF polymorphisms in susceptibility to differentiated thyroid carcinoma. 
  • Significance of microRNA-related variants in susceptibility to recurrence of oropharyngeal cancer patients after definitive radiotherapy. 
  • Single nucleotide polymorphism at rs1982073:T869C of the TGFbeta 1 gene is associated with the risk of radiation pneumonitis in patients with non-small-cell lung cancer treated with definitive radiotherapy. 
  • Single nucleotide polymorphisms and inherited risk of chronic lymphocytic leukemia among African Americans. 
  • Single nucleotide polymorphisms in multiple novel thrombospondin genes may be associated with familial premature myocardial infarction. 
  • Single nucleotide polymorphisms in the TP53 region and susceptibility to invasive epithelial ovarian cancer. 
  • Single nucleotide polymorphisms of matrix metallopeptidase 3 and risk of gliomas in a Chinese Han population. 
  • Single-nucleotide polymorphism alleles in the insulin receptor gene are associated with typical migraine. 
  • Single-nucleotide polymorphisms in nucleotide excision repair genes, cigarette smoking, and the risk of head and neck cancer. 
  • Single-nucleotide polymorphisms of stemness genes predicted to regulate RNA splicing, microRNA and oncogenic signaling are associated with prostate cancer survival. 
  • Single-port risk-reducing salpingo-oophorectomy with and without hysterectomy: surgical outcomes and learning curve analysis. 
  • Six-Year Incidence and Risk Factors of Age-Related Macular Degeneration in Singaporean Indians: The Singapore Indian Eye Study. 
  • Skeletal muscle-specific genetic determinants contribute to the differential strain-dependent effects of hindlimb ischemia in mice. 
  • Slip-sliding away: serial changes and homoplasy in repeat number in the Drosophila yakuba homolog of human cancer susceptibility gene BRCA2. 
  • Small changes in expression affect predisposition to tumorigenesis. 
  • Society of Gynecologic Oncologists Education Committee statement on risk assessment for inherited gynecologic cancer predispositions. 
  • Solid tumor second primary neoplasms: who is at risk, what can we do? 
  • Statistical models for haplotype sharing in case-parent trio data. 
  • Steroid 5-alpha-reductase type 2 (SRD5A2) V89L and A49T polymorphisms and sporadic prostate cancer risk: a meta-analysis. 
  • Strain-dependent genomic factors affect allergen-induced airway hyperresponsiveness in mice. 
  • Strategies for dissecting genetic-environmental interactions in neurodegenerative disorders. 
  • Strategy for investigating interactions between measured genes and measured environments. 
  • Stratified whole genome linkage analysis of Chiari type I malformation implicates known Klippel-Feil syndrome genes as putative disease candidates. 
  • Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration. 
  • Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration. 
  • Stress, COMT Polymorphisms, and Depressive Symptoms in Older Australian Women: An Exploratory Study. 
  • Striking a balance in communicating pharmacogenetic test results: promoting comprehension and minimizing adverse psychological and behavioral response. 
  • Study design for genetic analysis in the Jackson Heart Study. 
  • Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. 
  • Study of a US cohort supports the role of ZNF644 and high-grade myopia susceptibility. 
  • Studying genetic resilience to improve human health. 
  • Subacute limb ischemia induces skeletal muscle injury in genetically susceptible mice independent of vascular density. 
  • Summarizing and quantifying multilocus linkage disequilibrium patterns with multi-order Markov chain models. 
  • Summarizing polygenic risks for complex diseases in a clinical whole-genome report. 
  • Support for TGFB1 as a susceptibility gene for high myopia in individuals of Chinese descent. 
  • Surgical necrotizing enterocolitis in extremely premature neonates is associated with genetic variations in an intergenic region of chromosome 8. 
  • Surgical risk-reduction in carriers of BRCA mutations: where do we go from here? 
  • Survey of familial glioma and role of germline p16INK4A/p14ARF and p53 mutation. 
  • Susceptibility Loci for Clinical Coronary Artery Disease and Subclinical Coronary Atherosclerosis Throughout the Life-Course. 
  • Susceptibility loci of CNOT6 in the general mRNA degradation pathway and lung cancer risk-A re-analysis of eight GWASs. 
  • Susceptibility locus for clinical and subclinical coronary artery disease at chromosome 9p21 in the multi-ethnic ADVANCE study. 
  • Susceptibility of cyclooxygenase-2-deficient mice to pulmonary fibrogenesis. 
  • Susceptibility of transgenic mice expressing human apolipoprotein E to closed head injury: the allele E3 is neuroprotective whereas E4 increases fatalities. 
  • Susceptibility to childhood-onset rheumatoid arthritis: investigation of a weighted genetic risk score that integrates cumulative effects of variants at five genetic loci. 
  • Susceptibility to pancreatitis related to PSTI/SPINK1 expression. 
  • Susceptibility to vascular neoplasms but no increased susceptibility to renal carcinogenesis in Vhl knockout mice. 
  • Synaptic, transcriptional and chromatin genes disrupted in autism. 
  • Syndrome of hepatic cirrhosis, dystonia, polycythemia, and hypermanganesemia caused by mutations in SLC30A10, a manganese transporter in man. 
  • Systematic Functional Testing of Rare Variants: Contributions of CFI to Age-Related Macular Degeneration. 
  • Systematic Review and Meta-analysis: Gene Association Studies in Neonatal Sepsis. 
  • Systematic detection of positive selection in the human-pathogen interactome and lasting effects on infectious disease susceptibility. 
  • Systematic reconstruction of autism biology from massive genetic mutation profiles. 
  • Systematic search for susceptibility genes in different populations. 
  • Systemic lupus erythematosus and genetic variation in the interleukin 1 gene cluster: a population based study in the southeastern United States. 
  • Systemic, Ocular and Genetic Risk Factors for Age-related Macular Degeneration and Polypoidal Choroidal Vasculopathy in Singaporeans. 
  • Systems Pharmacogenomics Finds RUNX1 Is an Aspirin-Responsive Transcription Factor Linked to Cardiovascular Disease and Colon Cancer. 
  • Systems genetics identifies a role for Cacna2d1 regulation in elevated intraocular pressure and glaucoma susceptibility. 
  • T (brachyury) gene duplication confers major susceptibility to familial chordoma. 
  • T-cell receptor and carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis: understanding a hypersensitivity reaction. 
  • TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal. 
  • TET2 mutations improve the new European LeukemiaNet risk classification of acute myeloid leukemia: a Cancer and Leukemia Group B study. 
  • TM4SF20 ancestral deletion and susceptibility to a pediatric disorder of early language delay and cerebral white matter hyperintensities. 
  • TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions. 
  • TNF-α promoter polymorphisms and risk of recurrence in patients with squamous cell carcinomas of the nonoropharynx. 
  • TOLLIP, MUC5B, and the Response to N-Acetylcysteine among Individuals with Idiopathic Pulmonary Fibrosis. 
  • TOMM40'523 variant and cognitive decline in older persons with APOE ε3/3 genotype. 
  • TP53 Germline Variations Influence the Predisposition and Prognosis of B-Cell Acute Lymphoblastic Leukemia in Children. 
  • TP53 intron 1 hotspot rearrangements are specific to sporadic osteosarcoma and can cause Li-Fraumeni syndrome. 
  • Tagging single nucleotide polymorphisms in MBD4 are associated with risk of lung cancer in a Chinese population. 
  • Tagging single nucleotide polymorphisms in cell cycle control genes and susceptibility to invasive epithelial ovarian cancer. 
  • Tagging single nucleotide polymorphisms in excision repair cross-complementing group 1 (ERCC1) and risk of primary lung cancer in a Chinese population. 
  • Tagging single nucleotide polymorphisms in phosphoinositide-3-kinase-related protein kinase genes involved in DNA damage "checkpoints" and lung cancer susceptibility. 
  • Tamoxifen and the risk of ovarian cancer in BRCA1 mutation carriers. 
  • Telomere length and TERT functional polymorphisms are not associated with risk of squamous cell carcinoma of the head and neck. 
  • Telomere length connects melanoma and glioma predispositions. 
  • Telomere structure and maintenance gene variants and risk of five cancer types. 
  • Testicular cancer survivorship: research strategies and recommendations. 
  • Testing different communication formats on responses to imagined risk of having versus missing the GSTM1 gene. 
  • Testing for hereditary breast and ovarian cancer in the southeastern United States. 
  • Testing for risk and protective trends in genetic analyses of HIV acquisition. 
  • Testing for the recurrent HOXB13 G84E germline mutation in men with clinical indications for prostate biopsy. 
  • Testing gene-treatment interactions in pharmacogenetic studies. 
  • Testing the effect of rare compound-heterozygous and recessive mutations in case--parent sequencing studies. 
  • Testosterone regulates cell proliferation in aggressive fibromatosis (desmoid tumour). 
  • The Alzheimer diseases. 
  • The Effect of Gene Alterations and Tyrosine Kinase Inhibition on Survival and Cause of Death in Patients With Adenocarcinoma of the Lung and Brain Metastases. 
  • The Effects of RANTES Polymorphisms on Susceptibility to HIV-1 Infection and Disease Progression: Evidence from an Updated Meta-Analysis. 
  • The Finland-United States investigation of non-insulin-dependent diabetes mellitus genetics (FUSION) study. I. An autosomal genome scan for genes that predispose to type 2 diabetes. 
  • The Finland-United States investigation of non-insulin-dependent diabetes mellitus genetics (FUSION) study. II. An autosomal genome scan for diabetes-related quantitative-trait loci. 
  • The FoxO3 gene and cause-specific mortality. 
  • The Genetic Basis of Hydrocephalus. 
  • The Genetics of Endophenotypes of Neurofunction to Understand Schizophrenia (GENUS) consortium: A collaborative cognitive and neuroimaging genetics project. 
  • The Glioma International Case-Control Study: A Report From the Genetic Epidemiology of Glioma International Consortium. 
  • The Legacy of Past Pandemics: Common Human Mutations That Protect against Infectious Disease. 
  • The MedSeq Project: a randomized trial of integrating whole genome sequencing into clinical medicine. 
  • The NEIGHBOR consortium primary open-angle glaucoma genome-wide association study: rationale, study design, and clinical variables. 
  • The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers. 
  • The PLATO trial reveals further opportunities to improve outcomes in patients with acute coronary syndrome. Editorial on Serebruany. "Viewpoint: Paradoxical excess mortality in the PLATO trial should be independently verified" (Thromb Haemost 2011; 105.5). 
  • The Pl(A2) polymorphism of integrin beta(3) enhances outside-in signaling and adhesive functions. 
  • The Psychiatric Genomics Consortium Posttraumatic Stress Disorder Workgroup: Posttraumatic Stress Disorder Enters the Age of Large-Scale Genomic Collaboration. 
  • The Q7R Saitohin gene polymorphism is not associated with Alzheimer disease. 
  • The SSV Evaluation System: A Tool to Prioritize Short Structural Variants for Studies of Possible Regulatory and Causal Variants. 
  • The TOMM40 poly-T rs10524523 variant is associated with cognitive performance among non-demented elderly with type 2 diabetes. 
  • The VEGF -634G>C promoter polymorphism is associated with risk of gastric cancer. 
  • The adolescent obesity epidemic: why, how long, and what to do about it. 
  • The alpha-synuclein gene is not a major risk factor in familial Parkinson disease. 
  • The apolipoprotein E epsilon2 allele and aging-associated health deterioration in older males. 
  • The apolipoprotein E genotype predicts longitudinal transitions to mild cognitive impairment but not to Alzheimer's dementia: findings from a nationally representative study. 
  • The association of lumbar spondylolisthesis with collagen IX tryptophan alleles. 
  • The association of polymorphisms of CDT1 and GMNN gene with the risk of breast cancer in Chinese women: a case-control analysis. 
  • The beta3 subunit of the Na+,K+-ATPase mediates variable nociceptive sensitivity in the formalin test. 
  • The brain-derived neurotrophic factor Val66Met polymorphism, hippocampal volume, and cognitive function in geriatric depression. 
  • The broader autism phenotype in simplex and multiplex families. 
  • The cis-regulatory effect of an Alzheimer's disease-associated poly-T locus on expression of TOMM40 and apolipoprotein E genes. 
  • The clinical spectrum of female epilepsy patients with PCDH19 mutations in a Chinese population. 
  • The continuum of causality in human genetic disorders. 
  • The current clinical value of the DCIS Score. 
  • The dawn of genetic testing for glaucoma. 
  • The effect of SNCA 3' region on the levels of SNCA-112 splicing variant. 
  • The effects of the TOMM40 poly-T alleles on Alzheimer's disease phenotypes. 
  • The feasibility of online genetic testing for lung cancer susceptibility: uptake of a web-based protocol and decision outcomes. 
  • The frequency of anticardiolipin antibodies and genetic mutations associated with hypercoagulability among patients with Wegener's granulomatosis with and without history of a thrombotic event. 
  • The functional IGFBP7 promoter -418G>A polymorphism and risk of head and neck cancer. 
  • The functional promoter polymorphism (-842G>C) in the PIN1 gene is associated with decreased risk of breast cancer in non-Hispanic white women 55 years and younger. 
  • The genetic architecture of type 2 diabetes. 
  • The genetic attributable risk of breast and ovarian cancer. 
  • The genetic determinants of smoking. 
  • The genetic regulatory signature of type 2 diabetes in human skeletal muscle. 
  • The genetic response to short-term interventions affecting cardiovascular function: rationale and design of the Heredity and Phenotype Intervention (HAPI) Heart Study. 
  • The genetics of neuropsychiatric diseases: looking in and beyond the exome. 
  • The genetics of primary open-angle glaucoma: a review. 
  • The genetics of the J wave patterns. 
  • The hOGG1 Ser326Cys polymorphism and lung cancer risk: a meta-analysis. 
  • The hereditary nature of small cell carcinoma of the ovary, hypercalcemic type: two new familial cases. 
  • The heritability and sibling risk of angle closure in Asians. 
  • The heritability of breast cancer: a Bayesian correlated frailty model applied to Swedish twins data. 
  • The impact of cystic fibrosis and PSTI/SPINK1 gene mutations on susceptibility to chronic pancreatitis. 
  • The implications of genetics studies of major mood disorders for clinical practice. 
  • The importance of being connected. 
  • The importance of dynamic re-analysis in diagnostic whole exome sequencing. 
  • The influence of innate immunity gene receptors polymorphisms in renal transplant infections. 
  • The integration of molecular diagnostics with therapeutics. Implications for drug development and pathology practice. 
  • The kidney and hypertension: lessons from mouse models. 
  • The lta4h locus modulates susceptibility to mycobacterial infection in zebrafish and humans. 
  • The miR-184 binding-site rs8126 T>C polymorphism in TNFAIP2 is associated with risk of gastric cancer. 
  • The moderating effect of the APOE [small element of] 4 allele on the relationship between hippocampal volume and cognitive decline in older depressed patients. 
  • The neuregulin 1 promoter polymorphism rs6994992 is not associated with chronic schizophrenia or neurocognition. 
  • The neurobiology of individual differences in complex behavioral traits. 
  • The neutral theory and natural selection in the HLA region. 
  • The oligogenic properties of Bardet-Biedl syndrome. 
  • The oncocytic subtype is genetically distinct from other pancreatic intraductal papillary mucinous neoplasm subtypes. 
  • The pathobiology of vascular malformations: insights from human and model organism genetics. 
  • The polymorphic exon 1 androgen receptor CAG repeat in men with a potential inherited predisposition to prostate cancer. 
  • The potential of DISC1 protein as a therapeutic target for mental illness. 
  • The potential to predict the course of childhood asthma. 
  • The prediction of disease risk in genomic medicine. 
  • The predictive capacity of personal genome sequencing. 
  • The relationship between methylenetetrahydrofolate reductase polymorphism and hematological malignancy. 
  • The relationship between retinal arteriolar and venular calibers is genetically mediated, and each is associated with risk of cardiovascular disease. 
  • The role of KRAS rs61764370 in invasive epithelial ovarian cancer: implications for clinical testing. 
  • The role of cystic fibrosis gene mutations in determining susceptibility to chronic pancreatitis. 
  • The role of genetic testing for cancer susceptibility in gynecologic practice. 
  • The role of genetics in susceptibility to diabetic retinopathy. 
  • The role of hPMS1 and hPMS2 in predisposing to colorectal cancer. 
  • The role of polymorphisms in circadian pathway genes in breast tumorigenesis. 
  • The rs4774 CIITA missense variant is associated with risk of systemic lupus erythematosus. 
  • The six-nucleotide deletion/insertion variant in the CASP8 promoter region is inversely associated with risk of squamous cell carcinoma of the head and neck. 
  • The state of genome-wide association studies in pulmonary disease: a new perspective. 
  • The therapeutic potential of LRRK2 and alpha-synuclein in Parkinson's disease. 
  • The validity of the family history screen for assessing family history of mental disorders. 
  • The vitamin D receptor gene as a determinant of survival in pancreatic cancer patients: Genomic analysis and experimental validation. 
  • Three cases of multi-generational Pompe disease: Are current practices missing diagnostic and treatment opportunities? 
  • Three novel genetic variants in NRF2 signaling pathway genes are associated with pancreatic cancer risk. 
  • Three polymorphisms in cytochrome P450 1B1 (CYP1B1) gene and breast cancer risk: a meta-analysis. 
  • Thrombomodulin gene variants are associated with increased mortality after coronary artery bypass surgery in replicated analyses. 
  • Thrombophilias: when should we test and how does it help? 
  • Thymic epithelial defects and predisposition to autoimmune disease in BB rats. 
  • Thymidylate synthase 5'- and 3'-untranslated region polymorphisms associated with risk and progression of squamous cell carcinoma of the head and neck. 
  • Toll-like receptor 1 polymorphisms increase susceptibility to candidemia. 
  • Toward deciphering the mechanistic role of variations in the Rep1 repeat site in the transcription regulation of SNCA gene. 
  • Trade-off in the effects of the apolipoprotein E polymorphism on the ages at onset of CVD and cancer influences human lifespan. 
  • Trade-offs in the effects of the apolipoprotein E polymorphism on risks of diseases of the heart, cancer, and neurodegenerative disorders: insights on mechanisms from the Long Life Family Study. 
  • Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation. 
  • Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders. 
  • Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights. 
  • Transethnic genome-wide scan identifies novel Alzheimer's disease loci. 
  • Transferability and fine-mapping of glucose and insulin quantitative trait loci across populations: CARe, the Candidate Gene Association Resource. 
  • Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia. 
  • Transforming growth factor beta receptor I polyalanine repeat polymorphism does not increase ovarian cancer risk. 
  • Translating genomic biomarkers into clinically useful diagnostics. 
  • Translating models of antisocial behavioral development into efficacious intervention policy to prevent adolescent violence. 
  • Traumatic stress and accelerated DNA methylation age: A meta-analysis. 
  • Treating depression after myocardial infarction: can selecting patients on the basis of genetic susceptibility improve psychiatric and medical outcomes? 
  • Treatment Gaps in Adults With Heterozygous Familial Hypercholesterolemia in the United States: Data From the CASCADE-FH Registry. 
  • Treatment of infertility does not increase the risk of ovarian cancer among women with a BRCA1 or BRCA2 mutation. 
  • Trends in the association of parental history of obesity over 60 years. 
  • Trial Design and Objectives for Castration-Resistant Prostate Cancer: Updated Recommendations From the Prostate Cancer Clinical Trials Working Group 3. 
  • Trinucleotide repeat polymorphisms in the androgen receptor gene and risk of ovarian cancer. 
  • Trio-based exome sequencing arrests de novo mutations in early-onset high myopia. 
  • Truncating variants in p53AIP1 disrupting DNA damage-induced apoptosis are associated with prostate cancer risk. 
  • Tumor necrosis factor-α induced protein 8 polymorphism and risk of non-Hodgkin's lymphoma in a Chinese population: a case-control study. 
  • Two HLA Class II Gene Variants Are Independently Associated with Pediatric Osteosarcoma Risk. 
  • Two genes on A/J chromosome 18 are associated with susceptibility to Staphylococcus aureus infection by combined microarray and QTL analyses. 
  • Two new susceptibility loci for Kawasaki disease identified through genome-wide association analysis. 
  • Two novel PRKCI polymorphisms and prostate cancer risk in an Eastern Chinese Han population. 
  • Two-locus genome-wide linkage scan for prostate cancer susceptibility genes with an interaction effect. 
  • Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma. 
  • Type 2 Diabetes Genetic Variants and Risk of Diabetic Retinopathy. 
  • Type 2 diabetes: evidence for linkage on chromosome 20 in 716 Finnish affected sib pairs. 
  • US physicians' attitudes toward genetic testing for cancer susceptibility. 
  • Ultra-rare genetic variation in common epilepsies: a case-control sequencing study. 
  • Uncoupling associations of risk alleles with endophenotypes and phenotypes: insights from the ApoB locus and heart-related traits. 
  • Understanding human variation in infectious disease susceptibility through clinical and cellular GWAS. 
  • Understanding risk for psychopathology through imaging gene-environment interactions. 
  • Understanding the genetics of APOE and TOMM40 and role of mitochondrial structure and function in clinical pharmacology of Alzheimer's disease. 
  • Unitary construct of generalized cognitive ability underlying BACS performance across psychotic disorders and in their first-degree relatives. 
  • Unraveling a multifactorial late-onset disease: from genetic susceptibility to disease mechanisms for age-related macular degeneration. 
  • Use of cancer susceptibility testing among primary care physicians. 
  • Using genetics to enable studies on the prevention of Alzheimer's disease. 
  • Uterine Fibroids: Burden and Unmet Medical Need. 
  • Utilizing population controls in rare-variant case-parent association tests. 
  • VCL-ALK renal cell carcinoma in children with sickle-cell trait: the eighth sickle-cell nephropathy? 
  • Validating genetic risk associations for ovarian cancer through the international Ovarian Cancer Association Consortium. 
  • Validation of association of the apolipoprotein E ε2 allele with neurodevelopmental dysfunction after cardiac surgery in neonates and infants. 
  • Validation of genome-wide prostate cancer associations in men of African descent. 
  • Validation of prostate cancer risk-related loci identified from genome-wide association studies using family-based association analysis: evidence from the International Consortium for Prostate Cancer Genetics (ICPCG). 
  • Validity of reported genetic risk factors for acute coronary syndrome. 
  • Vandetanib for the treatment of patients with locally advanced or metastatic hereditary medullary thyroid cancer. 
  • Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease. 
  • Variants in Notch signalling pathway genes, PSEN1 and MAML2, predict overall survival in Chinese patients with epithelial ovarian cancer. 
  • Variants in PPP3R1 and MAPT are associated with more rapid functional decline in Alzheimer's disease: the Cache County Dementia Progression Study. 
  • Variants in angiopoietin-2 (ANGPT2) contribute to variation in nocturnal oxyhaemoglobin saturation level. 
  • Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility. 
  • Variants in melanocortin 1 receptor gene contribute to risk of melanoma--a direct sequencing analysis in a Texas population. 
  • Variants in nucleotide excision repair core genes and susceptibility to recurrence of squamous cell carcinoma of the oropharynx. 
  • Variants in toll-like receptors 2 and 9 influence susceptibility to pulmonary tuberculosis in Caucasians, African-Americans, and West Africans. 
  • Variation in GRM3 affects cognition, prefrontal glutamate, and risk for schizophrenia. 
  • Variation in glucose homeostasis traits associated with P2RX7 polymorphisms in mice and humans. 
  • Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of alpha-synuclein. 
  • Variation within DNA repair pathway genes and risk of multiple sclerosis. 
  • Variation within MBP gene predicts disease course in multiple sclerosis. 
  • Variation within the type 2 diabetes susceptibility gene calpain-10 and polycystic ovary syndrome. 
  • Variations in Prkdc and susceptibility to benzene-induced toxicity in mice. 
  • Vascular risk factors and cognitive decline among elderly male twins. 
  • Vascular tone pathway polymorphisms in relation to primary open-angle glaucoma. 
  • Ventricular arrhythmia in the X-linked cardiomyopathy Barth syndrome. 
  • Vincristine-induced neuropathy as the initial presentation of charcot-marie-tooth disease in acute lymphoblastic leukemia: a Pediatric Oncology Group study. 
  • Vitamin D receptor gene as a candidate gene for Parkinson disease. 
  • Vulnerability genes or plasticity genes? 
  • What's New in Genetic Testing for Cancer Susceptibility? 
  • Whether ionizing radiation is a risk factor for schizophrenia spectrum disorders? 
  • Whole blood gene expression testing for coronary artery disease in nondiabetic patients: major adverse cardiovascular events and interventions in the PREDICT trial. 
  • Whole blood sequencing reveals circulating microRNA associations with high-risk traits in non-ST-segment elevation acute coronary syndrome. 
  • Whole exome sequencing of a dominant retinitis pigmentosa family identifies a novel deletion in PRPF31. 
  • Whole genome association studies in complex diseases: where do we stand? 
  • Whole-exome sequencing implicates UBE3D in age-related macular degeneration in East Asian populations. 
  • Whole-exome sequencing of a pedigree segregating asthma. 
  • Whole-genome sequencing of a single proband together with linkage analysis identifies a Mendelian disease gene. 
  • Why information alone is not enough: behavioral economics and the future of genomic medicine. 
  • Will tomorrow's medicines work for everyone? 
  • Wnt/β-catenin pathway in podocytes integrates cell adhesion, differentiation, and survival. 
  • Working memory impairment in probands with schizoaffective disorder and first degree relatives of schizophrenia probands extend beyond deficits predicted by generalized neuropsychological impairment. 
  • X-ray repair cross-complementing group 1 (XRCC1) single-nucleotide polymorphisms and the risk of salivary gland carcinomas. 
  • XPD/ERCC2 EXON 8 Polymorphisms: rarity and lack of significance in risk of squamous cell carcinoma of the head and neck. 
  • XPD/ERCC2 polymorphisms and risk of head and neck cancer: a case-control analysis. 
  • XRCC3 Thr241Met polymorphism and breast cancer risk: a meta-analysis. 
  • Xenobiotic-Metabolizing gene polymorphisms and ovarian cancer risk. 
  • Young age at diagnosis correlates with worse prognosis and defines a subset of breast cancers with shared patterns of gene expression. 
  • Young smokers' interpretations of the estimated lung cancer risk associated with a common genetic variant of low penetrance. 
  • [Human chromosome 8p11 (CHRNB3-CHRNA6) region gene polymorphisms and susceptibility to lung cancer in Chinese Han population]. 
  • c-Kit is essential for alveolar maintenance and protection from emphysema-like disease in mice. 
  • miR-449b rs10061133 and miR-4293 rs12220909 polymorphisms are associated with decreased esophageal squamous cell carcinoma in a Chinese population. 
  • p14ARF genetic polymorphisms and susceptibility to second primary malignancy in patients with index squamous cell carcinoma of the head and neck. 
  • p53 codon 72 Arg homozygotes are associated with an increased risk of cutaneous melanoma. 
  • p73 G4C14-to-A4T14 gene polymorphism and interaction with p53 exon 4 Arg72Pro on cancer susceptibility: a meta-analysis of the literature. 
  • p73 G4C14-to-A4T14 polymorphism and risk of human papillomavirus-associated squamous cell carcinoma of the oropharynx in never smokers and never drinkers. 
  • p73 G4C14-to-A4T14 polymorphism and risk of lung cancer. 
  • α1-Syntrophin Variant Identified in Drug-Induced Long QT Syndrome Increases Late Sodium Current. 
• 

  Keywords of People

  • Alexander, John Hunter Peel, Professor of Medicine, Medicine, Cardiology
  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Bowes Rickman, Catherine, Professor of Ophthalmology, Cell Biology
  • Buckley, Rebecca Hatcher, James Buren Sidbury Distinguished Professor of Pediatrics, in the School of Medicine, Immunology
  • Case, Laura Elizabeth, Associate Professor of Orthopaedic Surgery, Orthopaedics, Physical Therapy
  • Charles, Hal Cecil, Associate Professor of Radiology, Radiology
  • Clyde, Merlise, Professor of Statistical Science, Statistical Science
  • Dement, John McCray, Professor Emeritus in Family Medicine and Community Health, Family Medicine & Community Health,Occupational & Environmental Medicine
  • Dodge, Kenneth A., Pritzker Professor of Early Learning Policy Studies, Duke Science & Society
  • Freemark, Michael Scott, Robert C. Atkins, M.D. and Veronica Atkins Distinguished Professor of Pediatrics, in the School of Medicine, Pediatrics, Endocrinology
  • Halabi, Susan, Professor of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics
  • Jowell, Paul Simon, Professor of Medicine, Medicine, Gastroenterology
  • Laskowitz, Daniel Todd, Professor of Neurology, Duke Innovation & Entrepreneurship
  • Liu, Yutao, Adjunct Assistant Professor in the Department of Medicine, Medicine, Medical Genetics
  • McCall, Shannon Jones, Associate Professor of Pathology, Pathology
  • McCarthy, Janice Marie, Medical Instructor in Biostatistics and Bioinformatics, Biostatistics & Bioinformatics
  • McLendon, Roger Edwin, Professor of Pathology, Pathology
  • Milano, Carmelo Alessio, Professor of Surgery, Surgery, Cardiovascular and Thoracic Surgery
  • Moorman, Patricia Gripka, Professor in Family Medicine and Community Health, Duke Cancer Institute
  • Muir, Kelly Walton, Associate Professor of Ophthalmology, Ophthalmology, Glaucoma
  • Pang, Herbert, Adjunct Assistant Professor in the Department of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics
  • Patel, Uptal Dinesh, Adjunct Professor in the Department of Medicine, Medicine, Nephrology
  • Pitt, Geoffrey Stuart, Adjunct Professor in the Department of Medicine, Medicine, Cardiology
  • Reddy, Timothy E, Associate Professor of Biostatistics & Bioinformatics, Molecular Genetics and Microbiology
  • Shinohara, Mari L., Associate Professor of Immunology, Immunology
  • Silver, Debra Lynn, Associate Professor of Molecular Genetics and Microbiology, Duke Science & Society
  • Swaminathan, Madhav, Professor of Anesthesiology, Anesthesiology, Cardiothoracic
  • Taylor, Gregory Alan, Associate Professor in Medicine, Immunology
  • Warner, David Samuel, Distinguished Distinguished Professor of Anesthesiology, in the School of Medicine, Neurobiology
  • Wray, Gregory Allan, Professor of Biology, Duke Innovation & Entrepreneurship
  • Yancy Jr., William Samuel, Associate Professor of Medicine, Medicine, General Internal Medicine