Long Interspersed Nucleotide Elements
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Subject Areas on Research
- A phase 1 trial of the oral DNA methyltransferase inhibitor CC-486 and the histone deacetylase inhibitor romidepsin in advanced solid tumors.
- Azacitidine favorably modulates PSA kinetics correlating with plasma DNA LINE-1 hypomethylation in men with chemonaïve castration-resistant prostate cancer.
- Cellular inhibitors of long interspersed element 1 and Alu retrotransposition.
- DNA global hypomethylation in squamous cell head and neck cancer associated with smoking, alcohol consumption and stage.
- DNA methylation of individual repetitive elements in hepatitis C virus infection-induced hepatocellular carcinoma.
- Deletion of azoospermia factor a (AZFa) region of human Y chromosome caused by recombination between HERV15 proviruses.
- Linkage disequilibrium and signatures of positive selection around LINE-1 retrotransposons in the human genome.
- Prediction of genome-wide DNA methylation in repetitive elements.
- Selective inhibition of Alu retrotransposition by APOBEC3G.
- Site-specific silencing of regulatory elements as a mechanism of X inactivation.
- Social factors and leukocyte DNA methylation of repetitive sequences: the multi-ethnic study of atherosclerosis.
- Surgical necrotizing enterocolitis in extremely premature neonates is associated with genetic variations in an intergenic region of chromosome 8.