Chromosome Segregation
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Subject Areas on Research
- . Loss of sexual recombination and segregation is associated with increased diversification in evening primroses.
- A comprehensive model to predict mitotic division in budding yeasts.
- A developmentally regulated translational control pathway establishes the meiotic chromosome segregation pattern.
- A genetic memory initiates the epigenetic loop necessary to preserve centromere position.
- A novel meiotic drive locus almost completely distorts segregation in mimulus (monkeyflower) hybrids.
- Acetylation of Nup62 by TIP60 ensures accurate chromosome segregation in mitosis.
- Assembly pathway of the anastral Drosophila oocyte meiosis I spindle.
- Condensin and cohesin display different arm conformations with characteristic hinge angles.
- Determining centromere identity: cyclical stories and forking paths.
- Early Diverging Fungus Mucor circinelloides Lacks Centromeric Histone CENP-A and Displays a Mosaic of Point and Regional Centromeres.
- Environmental aridity is associated with cytotype segregation and polyploidy occurrence in Brachypodium distachyon (Poaceae).
- Evidence for the segregation of a major gene for human plasma GABA levels.
- Gene conversion occurs within the mating-type locus of Cryptococcus neoformans during sexual reproduction.
- Genetic divergence causes parallel evolution of flower color in Chilean Mimulus.
- Genetics of multiple sclerosis.
- Genomic and functional variation of human centromeres.
- How petals change their spots: cis-regulatory re-wiring in Clarkia (Onagraceae).
- Impaired Bub1 function in vivo compromises tension-dependent checkpoint function leading to aneuploidy and tumorigenesis.
- Interplay between structure-specific endonucleases for crossover control during Caenorhabditis elegans meiosis.
- Long transposon-rich centromeres in an oomycete reveal divergence of centromere features in Stramenopila-Alveolata-Rhizaria lineages.
- Loss of hPot1 function leads to telomere instability and a cut-like phenotype.
- Mapping of within-species segregation distortion in Drosophila persimilis and hybrid sterility between D. persimilis and D. pseudoobscura.
- Matroshka and ectopic polymorphisms: Two new classes of DNA sequence variation identified at the Van der Woude syndrome locus on 1q32-q41.
- Meiotic chromosome segregation in triploid strains of Saccharomyces cerevisiae.
- Molecular Analysis of pSK1 par: A Novel Plasmid Partitioning System Encoded by Staphylococcal Multiresistance Plasmids.
- Persistent DNA damage signaling and DNA polymerase theta promote broken chromosome segregation.
- Ploidy variation in multinucleate cells changes under stress.
- Proliferation of Double-Strand Break-Resistant Polyploid Cells Requires Drosophila FANCD2.
- Role of proliferating cell nuclear antigen interactions in the mismatch repair-dependent processing of mitotic and meiotic recombination intermediates in yeast.
- Sad1 Spatiotemporally Regulates Kinetochore Clustering To Ensure High-Fidelity Chromosome Segregation in the Human Fungal Pathogen Cryptococcus neoformans.
- Segrosome structure revealed by a complex of ParR with centromere DNA.
- Spatiotemporal regulation of Aurora B recruitment ensures release of cohesion during C. elegans oocyte meiosis.
- Stratified whole genome linkage analysis of Chiari type I malformation implicates known Klippel-Feil syndrome genes as putative disease candidates.
- Structural biology of plasmid partition: uncovering the molecular mechanisms of DNA segregation.
- Structures of ParB bound to DNA reveal mechanism of partition complex formation.
- Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages.
- Structures of partition protein ParA with nonspecific DNA and ParB effector reveal molecular insights into principles governing Walker-box DNA segregation.
- Structures of the nucleoid occlusion protein SlmA bound to DNA and the C-terminal domain of the cytoskeletal protein FtsZ.
- The C-terminal 20 Amino Acids of Drosophila Topoisomerase 2 Are Required for Binding to a BRCA1 C Terminus (BRCT) Domain-containing Protein, Mus101, and Fidelity of DNA Segregation.
- The genetic basis of a flower-color polymorphism in the common
- The genetic basis of developmental abnormalities in interpopulation hybrids of the moss Ceratodon purpureus.
- Transmission ratio distortion in intraspecific hybrids of Mimulus guttatus: implications for genomic divergence.
- Uncoupling of nucleotide hydrolysis and polymerization in the ParA protein superfamily disrupts DNA segregation dynamics.
- Unusual chromosome architecture and behaviour at an HSR.
- ZTF-8 interacts with the 9-1-1 complex and is required for DNA damage response and double-strand break repair in the C. elegans germline.
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Keywords of People
- Erickson, Harold Paul, James B. Duke Distinguished Professor Emeritus, Cell Biology
- Sullivan, Beth Ann, Professor of Molecular Genetics and Microbiology, Duke Science & Society
- Yadav, Vikas, Postdoctoral Associate, Molecular Genetics and Microbiology