Brefeldin A

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  Subject Areas on Research

  • A bacterial virulence protein suppresses host innate immunity to cause plant disease. 
  • Activation of the sphingomyelin cycle by brefeldin A: effects of brefeldin A on differentiation and implications for a role for ceramide in regulation of protein trafficking. 
  • Brefeldin A promotes hydrolysis of sphingomyelin. 
  • Brefeldin A rapidly disrupts plasma membrane polarity by blocking polar sorting in common endosomes of MDCK cells. 
  • Coupling endoplasmic reticulum stress to cell death program in isolated human pancreatic islets: effects of gene transfer of Bcl-2. 
  • Degradation of the Met tyrosine kinase receptor by the ubiquitin-proteasome pathway. 
  • Evaluating cytokine production by flow cytometry using brefeldin A in mice. 
  • Extracellular trafficking of myocilin in human trabecular meshwork cells. 
  • Prevention of brefeldin A-induced resistance to teniposide by the proteasome inhibitor MG-132: involvement of NF-kappaB activation in drug resistance. 
  • Prostaglandin A1 inhibits stress-induced NF-kappaB activation and reverses resistance to topoisomerase II inhibitors. 
  • Reversal of physiological stress-induced resistance to topoisomerase II inhibitors using an inducible phosphorylation site-deficient mutant of I kappa B alpha. 
  • The constitutive secretory pathway is a major route for islet amyloid polypeptide secretion in neonatal but not adult rat islet cells. 
  • The regulation of ferroptosis by MESH1 through the activation of the integrative stress response. 
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  Keywords of People

  • Taylor, Gregory Alan, Professor in Medicine, Integrative Immunobiology