Expressed Sequence Tags

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  Subject Areas on Research

  • A 4-Mb high-density single nucleotide polymorphism-based map around human APOE. 
  • A computational/functional genomics approach for the enrichment of the retinal transcriptome and the identification of positional candidate retinopathy genes. 
  • A first-generation X-inactivation profile of the human X chromosome. 
  • A framework phylogeny of the American oak clade based on sequenced RAD data. 
  • A human novel gene DERPC on 16q22.1 inhibits prostate tumor cell growth and its expression is decreased in prostate and renal tumors. 
  • A molecular basis for inositol polyphosphate synthesis in Drosophila melanogaster. 
  • A novel androgen-regulated gene, PMEPA1, located on chromosome 20q13 exhibits high level expression in prostate. 
  • A novel chromatin protein, distantly related to histone H2A, is largely excluded from the inactive X chromosome. 
  • A phosphorylated cytoplasmic autoantigen, GW182, associates with a unique population of human mRNAs within novel cytoplasmic speckles. 
  • A physical map of 30,000 human genes. 
  • A proteomic analysis of human cilia: identification of novel components. 
  • A radiation hybrid breakpoint map of the acute myeloid leukemia (AML) and limb-girdle muscular dystrophy 1A (LGMD1A) regions of chromosome 5q31 localizing 122 expressed sequences. 
  • A sea urchin genome project: sequence scan, virtual map, and additional resources. 
  • An evaluation of the draft human genome sequence. 
  • Analysis of expressed sequence tags from the fungus Aspergillus oryzae cultured under different conditions. 
  • Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. 
  • Analysis of transcripts expressed by Eimeria tenella oocysts using subtractive hybridization methods. 
  • CHST1 and CHST2 sulfotransferases expressed by human vascular endothelial cells: cDNA cloning, expression, and chromosomal localization. 
  • Cardiovascular genomics: estimating the total number of genes expressed in the human cardiovascular system. 
  • Characterization of gene expression in human trabecular meshwork using single-pass sequencing of 1060 clones. 
  • Chromosomal distribution of the human cardiovascular transcriptome. 
  • Cloning and characterization of PDE7B, a cAMP-specific phosphodiesterase. 
  • Computational analysis of core promoters in the Drosophila genome. 
  • Computational and experimental analyses reveal previously undetected coding exons of the KRIT1 (CCM1) gene. 
  • Cryptococcus neoformans gene expression during experimental cryptococcal meningitis. 
  • Differential gene expression patterns in HER2/neu-positive and -negative breast cancer cell lines and tissues. 
  • Differential var gene transcription in Plasmodium falciparum isolates from patients with cerebral malaria compared to hyperparasitaemia. 
  • Expressed sequence tag analysis in Cycas, the most primitive living seed plant. 
  • Genes upregulated in the human trabecular meshwork in response to elevated intraocular pressure. 
  • Genome annotation assessment in Drosophila melanogaster. 
  • Genomic convergence to identify candidate genes for Parkinson disease: SAGE analysis of the substantia nigra. 
  • Genomic convergence: identifying candidate genes for Parkinson's disease by combining serial analysis of gene expression and genetic linkage. 
  • Genomics and hypertension: concepts, potentials, and opportunities. 
  • Identification and isolation of differentially expressed genes from very small tissue samples. 
  • Identification of genes expressed in a human scleral cDNA library. 
  • Identification of novel genes preferentially expressed in the retina using a custom human retina cDNA microarray. 
  • Identification of the gene that, when mutated, causes the human obesity syndrome BBS4. 
  • Isolation of a paralog of the Doyne honeycomb retinal dystrophy gene from the multiple retinopathy critical region on 11q13. 
  • Low enzymatic activity haplotypes of the human catechol-O-methyltransferase gene: enrichment for marker SNPs. 
  • Molecular cloning and characterization of a distinct human phosphodiesterase gene family: PDE11A. 
  • Motif composition, conservation and condition-specificity of single and alternative transcription start sites in the Drosophila genome. 
  • Myotilin is mutated in limb girdle muscular dystrophy 1A. 
  • NEIBank: genomics and bioinformatics resources for vision research. 
  • No association of DYNC1H1 with sporadic ALS in a case-control study of a northern European derived population: a tagging SNP approach. 
  • Overexpression of the ETS-related gene, ERG, predicts a worse outcome in acute myeloid leukemia with normal karyotype: a Cancer and Leukemia Group B study. 
  • Regulatory network motifs and hotspots of cancer genes in a mammalian cellular signalling network. 
  • Serial analysis of gene expression (SAGE) in normal human trabecular meshwork. 
  • TBestDB: a taxonomically broad database of expressed sequence tags (ESTs). 
  • The LabFlow system for workflow management in large scale biology research laboratories. 
  • The phylogeny of extant starfish (Asteroidea: Echinodermata) including Xyloplax, based on comparative transcriptomics. 
  • The small subunit of the mammalian mitochondrial ribosome. Identification of the full complement of ribosomal proteins present. 
  • Transcriptome analysis of mouse stem cells and early embryos. 
  • U1 small nuclear RNA variants differentially form ribonucleoprotein particles in vitro. 
  • UCHL-1 gene in multiple system atrophy: a haplotype tagging approach. 
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  Keywords of People

  • Hogan, Brigid L. M., George Barth Geller Distinguished Professor, Cell Biology
  • Liu, Yutao, Adjunct Assistant Professor in the Department of Medicine, Medicine, Medical Genetics
  • Soderling, Scott Haydn, Professor in Cell Biology, Cell Biology