In Situ Nick-End Labeling
-
Subject Areas on Research
-
2,3,7,8-Tetrachlorodibenzo-p-dioxin induces apoptotic cell death and cytochrome P4501A expression in developing Fundulus heteroclitus embryos.
-
A clinically relevant model of perinatal global ischemic brain damage in rats.
-
A high-throughput histoarray for quantitative molecular profiling of multiple, uniformly oriented medaka (Oryzias latipes) embryos.
-
Adenovirus-mediated wild-type p53 tumor suppressor gene therapy induces apoptosis and suppresses growth of human pancreatic cancer [seecomments].
-
Adriamycin-induced senescence in breast tumor cells involves functional p53 and telomere dysfunction.
-
Allopregnanolone attenuates N-methyl-D-aspartate-induced excitotoxicity and apoptosis in the human NT2 cell line in culture.
-
Angiotensin protects cortical neurons from hypoxic-induced apoptosis via the angiotensin type 2 receptor.
-
Antiangiogenic treatment with the three thrombospondin-1 type 1 repeats recombinant protein in an orthotopic human pancreatic cancer model.
-
Antiangiogenic treatment with three thrombospondin-1 type 1 repeats versus gemcitabine in an orthotopic human pancreatic cancer model.
-
Apolipoprotein E Exerts a Whole-Brain Protective Property by Promoting M1? Microglia Quiescence After Experimental Subarachnoid Hemorrhage in Mice.
-
Apoptosis during coronary artery orifice development in the chick embryo.
-
Apoptosis is not enhanced in primary mixed neuronal/glial cultures protected by isoflurane against N-methyl-D-aspartate excitotoxicity.
-
BDNF-mediated cerebellar granule cell development is impaired in mice null for CaMKK2 or CaMKIV.
-
Bcl-2 accelerates multistep prostate carcinogenesis in vivo.
-
Benzodiazepines protect hippocampal neurons from degeneration after transient cerebral ischemia: an ultrastructural study.
-
Blockade of the epidermal growth factor receptor signaling by a novel tyrosine kinase inhibitor leads to apoptosis of endothelial cells and therapy of human pancreatic carcinoma.
-
CD10/neutral endopeptidase inhibition augments pulmonary neuroendocrine cell hyperplasia in hamsters treated with diethylnitrosamine and hyperoxia.
-
CDB-4124 does not cause apoptosis in cultured fibroid cells.
-
Calpain mediates ischemic injury of the liver through modulation of apoptosis and necrosis.
-
Carbon monoxide induces cytoprotection in rat orthotopic lung transplantation via anti-inflammatory and anti-apoptotic effects.
-
Carbon monoxide inhibition of apoptosis during ischemia-reperfusion lung injury is dependent on the p38 mitogen-activated protein kinase pathway and involves caspase 3.
-
Cardiomyocyte-Specific Human Bcl2-Associated Anthanogene 3 P209L Expression Induces Mitochondrial Fragmentation, Bcl2-Associated Anthanogene 3 Haploinsufficiency, and Activates p38 Signaling.
-
Changes in sphingomyelinases, ceramide, Bax, Bcl(2), and caspase-3 during and after experimental status epilepticus.
-
Cholestyramine feeding lowers number of colonic apoptotic cells in rat.
-
Chronic recurrent myocardial ischemic injury is significantly attenuated by pre-emptive adeno-associated virus heme oxygenase-1 gene delivery.
-
Cyclin D1 overexpression and response to bortezomib treatment in a breast cancer model.
-
Cytogenetics and mechanisms of spontaneous abortions: increased apoptosis and decreased cell proliferation in chromosomally abnormal villi.
-
Defining a link with autosomal-dominant polycystic kidney disease in mice with congenitally low expression of Pkd1.
-
Delayed myocardial preconditioning by alpha1-adrenoceptors involves inhibition of apoptosis.
-
Deletion of PIK3C3/Vps34 in sensory neurons causes rapid neurodegeneration by disrupting the endosomal but not the autophagic pathway.
-
Depletion of passenger leukocytes from corneal grafts: an effective means of promoting transplant survival?
-
Development of biologic markers of response and assessment of antiangiogenic activity in a clinical trial of human recombinant endostatin.
-
Disruption of ErbB receptor signaling in adult non-myelinating Schwann cells causes progressive sensory loss.
-
Dual inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation by AEE788 reduces growth and metastasis of human colon carcinoma in an orthotopic nude mouse model.
-
Effect of flaxseed supplementation on prostatic carcinoma in transgenic mice.
-
Endothelial cell and hepatocyte deaths occur by apoptosis after ischemia-reperfusion injury in the rat liver.
-
Enhanced H(2)O(2)-induced cytotoxicity in "epithelioid" smooth muscle cells: implications for neointimal regression.
-
Epidermal growth factor receptor blockade with C225 plus gemcitabine results in regression of human pancreatic carcinoma growing orthotopically in nude mice by antiangiogenic mechanisms.
-
FGF signaling regulates rod photoreceptor cell maintenance and regeneration in zebrafish.
-
Fas/FasL play a central role in pancreatitis-induced hepatocyte apoptosis.
-
Flupirtine blocks apoptosis in batten patient lymphoblasts and in human postmitotic CLN3- and CLN2-deficient neurons.
-
Gamma radiation-induced apoptosis, G2 delay, and the risk of salivary and thyroid carcinomas--a preliminary report.
-
Generation of a syngeneic mouse model to study the effects of vascular endothelial growth factor in ovarian carcinoma.
-
HASF is a stem cell paracrine factor that activates PKC epsilon mediated cytoprotection.
-
HIV-1 induces renal epithelial dedifferentiation in a transgenic model of HIV-associated nephropathy.
-
Hypoxic cell death is reduced by pH buffering in a model of engineered heart tissue.
-
Identification of potassium-dependent and -independent components of the apoptotic machinery in mouse ovarian germ cells and granulosa cells.
-
Indispensable pre-mitotic endocycles promote aneuploidy in the Drosophila rectum.
-
Induction of apoptosis in tumor-associated endothelial cells and therapy of orthotopic human pancreatic carcinoma in nude mice.
-
Interleukin 12 protects from a T helper type 1-mediated autoimmune disease, experimental autoimmune uveitis, through a mechanism involving interferon gamma, nitric oxide, and apoptosis.
-
JNK1 is required to preserve cardiac function in the early response to pressure overload.
-
KRAS2 mutations in human pancreatic acinar-ductal metaplastic lesions are limited to those with PanIN: implications for the human pancreatic cancer cell of origin.
-
Lack of apoptosis in the hypoxic brain of a rat model mimicking cyanotic heart disease.
-
Long-term effects of acute and of chronic hypoxia on behavior and on hippocampal histology in the developing brain.
-
Manganese porphyrin reduces retinal injury induced by ocular hypertension in rats.
-
Mitochondrial proteins that regulate apoptosis and necrosis are induced in mouse fatty liver.
-
NMDA-induced apoptosis in mixed neuronal/glial cortical cell cultures: the effects of isoflurane and dizocilpine.
-
Neuronal apoptosis associated with morphine tolerance: evidence for an opioid-induced neurotoxic mechanism.
-
Neuronal pentraxin 1: a novel mediator of hypoxic-ischemic injury in neonatal brain.
-
Neurotrophin-3 mediates the autocrine survival of the catecholaminergic CAD CNS neuronal cell line.
-
Nrf2-mediated protection against 6-hydroxydopamine.
-
Overexpression of caspase-3 in hepatocellular carcinomas.
-
PTHrP regulates growth plate chondrocyte differentiation and proliferation in a Gli3 dependent manner utilizing hedgehog ligand dependent and independent mechanisms.
-
Peptide elongation factor eEF1A-2/S1 expression in cultured differentiated myotubes and its protective effect against caspase-3-mediated apoptosis.
-
Piezo-assisted nuclear transfer affects cloning efficiency and may cause apoptosis.
-
Pilot study of dietary fat restriction and flaxseed supplementation in men with prostate cancer before surgery: exploring the effects on hormonal levels, prostate-specific antigen, and histopathologic features.
-
Preclinical evidence for therapeutic efficacy of selective estrogen receptor modulators for uterine leiomyoma.
-
Programmed cell death in the lithium pilocarpine model: evidence for NMDA receptor and ceramide-mediated mechanisms.
-
Quantifiable Biomarkers of Normal Aging in the Japanese Medaka Fish (Oryzias latipes)
-
Quantitative analysis of biomarkers defines an optimal biological dose for recombinant human endostatin in primary human tumors.
-
RGD peptide-assisted vitrectomy to facilitate induction of a posterior vitreous detachment: a new principle in pharmacological vitreolysis.
-
Reproductive cytotoxicity is predicted by magnetic resonance microscopy and confirmed by ubiquitin-proteasome immunohistochemistry in a theophylline-induced model of rat testicular and epididymal toxicity.
-
Resistance to cerebral ischemic injury in UCP2 knockout mice: evidence for a role of UCP2 as a regulator of mitochondrial glutathione levels.
-
Restriction of hepatic competence by Fgf signaling.
-
Role of early growth response-1 (Egr-1) in interleukin-13-induced inflammation and remodeling.
-
Role of the Fas-signaling pathway in photoreceptor neuroprotection.
-
Secreted frizzled related protein 2 protects cells from apoptosis by blocking the effect of canonical Wnt3a.
-
Simultaneous inhibition of EGFR, VEGFR, and platelet-derived growth factor receptor signaling combined with gemcitabine produces therapy of human pancreatic carcinoma and prolongs survival in an orthotopic nude mouse model.
-
Study of the biologic effects of lapatinib, a reversible inhibitor of ErbB1 and ErbB2 tyrosine kinases, on tumor growth and survival pathways in patients with advanced malignancies.
-
Survival of subretinal pancreatic islet cell allografts and apoptosis in infiltrating lymphocytes in rats.
-
Systemic administration of the iron chelator deferiprone protects against light-induced photoreceptor degeneration in the mouse retina.
-
Targeted activation of c-Jun N-terminal kinase in vivo induces restrictive cardiomyopathy and conduction defects.
-
Targeted inactivation of synaptic HRG4 (UNC119) causes dysfunction in the distal photoreceptor and slow retinal degeneration, revealing a new function.
-
Targeting A20 decreases glioma stem cell survival and tumor growth.
-
Targeting the Tie2/Tek receptor in astrocytomas.
-
Targeting tumor microvessels using doxorubicin encapsulated in a novel thermosensitive liposome.
-
Tea consumption, apoptosis, and colorectal adenomas.
-
The effect of dexamethasone on the generation of plasma DNA from dead and dying cells.
-
The exon junction complex component Magoh controls brain size by regulating neural stem cell division.
-
The zinc finger transcription factor ZFX is required for maintaining the tumorigenic potential of glioblastoma stem cells.
-
Trans-arachidonic acids generated during nitrative stress induce a thrombospondin-1-dependent microvascular degeneration.
-
Trophic effects of androgen: development and hormonal regulation of neuron number in a sexually dimorphic vocal motor nucleus.
-
VEGF-induced heme oxygenase-1 confers cytoprotection from lethal hyperoxia in vivo.
-
Viability and apoptosis of human chondrocytes in osteochondral fragments following joint trauma.