Brain Stem Neoplasms
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Subject Areas on Research
- A high-throughput in vitro drug screen in a genetically engineered mouse model of diffuse intrinsic pontine glioma identifies BMS-754807 as a promising therapeutic agent.
- A machine learning-based prediction model of H3K27M mutations in brainstem gliomas using conventional MRI and clinical features.
- A phase II study of O6-benzylguanine and temozolomide in pediatric patients with recurrent or progressive high-grade gliomas and brainstem gliomas: a Pediatric Brain Tumor Consortium study.
- ABC Transporter Inhibition Plus Dexamethasone Enhances the Efficacy of Convection Enhanced Delivery in H3.3K27M Mutant Diffuse Intrinsic Pontine Glioma.
- ACVR1 R206H cooperates with H3.1K27M in promoting diffuse intrinsic pontine glioma pathogenesis.
- Brain stem gliomas: patterns of care in Victoria from 1998-2000.
- Brainstem auditory evoked potential monitoring: when is change in wave V significant?
- Brainstem melanomas presenting as a cavernous malformation.
- Brainstem stereotactic biopsy sampling in children.
- Cerebellopontine angle meningiomas: postoperative outcomes in a modern cohort.
- Characteristics of patients ≥10 years of age with diffuse intrinsic pontine glioma: a report from the International DIPG/DMG Registry.
- Children are not just little adults: recent advances in understanding of diffuse intrinsic pontine glioma biology.
- Clinical characteristics and treatment of malignant brainstem gliomas in elderly patients.
- Epidemiology of brainstem high-grade gliomas in children and adolescents in the United States, 2000-2017.
- Etoposide, vincristine, and cyclosporin A with standard-dose radiation therapy in newly diagnosed diffuse intrinsic brainstem gliomas: a pediatric oncology group phase I study.
- Evaluation of 18F-FDG PET and MRI associations in pediatric diffuse intrinsic brain stem glioma: a report from the Pediatric Brain Tumor Consortium.
- Exome sequencing identifies somatic gain-of-function PPM1D mutations in brainstem gliomas.
- GD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas.
- Histone H3.3K27M Represses p16 to Accelerate Gliomagenesis in a Murine Model of DIPG.
- Incidence and patterns of neuraxis metastases in children with diffuse pontine glioma.
- Intensity-modulated stereotactic radiosurgery using dynamic micro-multileaf collimation.
- Intraaxial dermoid cyst of the medulla.
- Lack of efficacy of bevacizumab plus irinotecan in children with recurrent malignant glioma and diffuse brainstem glioma: a Pediatric Brain Tumor Consortium study.
- Local delivery methods of therapeutic agents in the treatment of diffuse intrinsic brainstem gliomas.
- Malignant brainstem gliomas in adults: clinicopathological characteristics and prognostic factors.
- Management of intrinsic gliomas of the tectal plate in children. A ten-year review.
- Neurophysiologic intraoperative monitoring of the glossopharyngeal and vagus nerves.
- PD-0332991, a CDK4/6 inhibitor, significantly prolongs survival in a genetically engineered mouse model of brainstem glioma.
- PPM1D mutations are oncogenic drivers of de novo diffuse midline glioma formation.
- Phase I trial of imatinib in children with newly diagnosed brainstem and recurrent malignant gliomas: a Pediatric Brain Tumor Consortium report.
- Preoperative evaluation of neural tracts by use of three-dimensional anisotropy contrast imaging in a patient with brainstem cavernous angioma: technical case report.
- Prospective feasibility and safety assessment of surgical biopsy for patients with newly diagnosed diffuse intrinsic pontine glioma.
- Radiosensitizing the Vasculature of Primary Brainstem Gliomas Fails to Improve Tumor Response to Radiation Therapy.
- Surgical management of brainstem cavernomas: selection of approaches and microsurgical techniques.
- Symptomatic brainstem cavernomas.
- TP53 wild-type/PPM1D mutant diffuse intrinsic pontine gliomas are sensitive to a MDM2 antagonist.
- Targeting Mutant PPM1D Sensitizes Diffuse Intrinsic Pontine Glioma Cells to the PARP Inhibitor Olaparib.
- The H3.3 K27M mutation results in a poorer prognosis in brainstem gliomas than thalamic gliomas in adults.
- The integrated genomic and epigenomic landscape of brainstem glioma.
- The presigmoid approach to anterolateral pontine cavernomas. Clinical article.
- Tumor genotype dictates radiosensitization after Atm deletion in primary brainstem glioma models.
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Keywords of People
- McLendon, Roger Edwin, Professor of Pathology, Pathology