Rats, Long-Evans

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  Subject Areas on Research

  • A Brain to Spine Interface for Transferring Artificial Sensory Information. 
  • A Closed Loop Brain-machine Interface for Epilepsy Control Using Dorsal Column Electrical Stimulation. 
  • A brain-to-brain interface for real-time sharing of sensorimotor information. 
  • A calcium-responsive transcription factor, CaRF, that regulates neuronal activity-dependent expression of BDNF. 
  • A controlled high-fat diet induces an obese syndrome in rats. 
  • A distinctive subpopulation of medial septal slow-firing neurons promote hippocampal activation and theta oscillations. 
  • A multi-channel whisker stimulator for producing spatiotemporally complex tactile stimuli. 
  • Absolute measurements of water content using magnetic resonance imaging: preliminary findings in an in vivo focal ischemic rat model. 
  • Acquiring local field potential information from amperometric neurochemical recordings. 
  • Age- and gender-related differences in sensitivity to chlorpyrifos in the rat reflect developmental profiles of esterase activities. 
  • Age-independent and dose-response effects of ethanol on spatial memory in rats. 
  • An NMDA antagonist in the MPOA impairs copulation and stimulus sensitization in male rats. 
  • An absolute measurement of brain water content using magnetic resonance imaging in two focal cerebral ischemic rat models. 
  • Apolipoprotein A-IV interacts synergistically with melanocortins to reduce food intake. 
  • Appetitive changes during salt deprivation are paralleled by widespread neuronal adaptations in nucleus accumbens, lateral hypothalamus, and central amygdala. 
  • Automated measurement of acetylcholinesterase activity in rat peripheral tissues. 
  • Basal forebrain dynamics during a tactile discrimination task. 
  • Behavioral and neural responses to gustatory stimuli delivered non-contingently through intra-oral cannulas. 
  • Behavioral detection of tactile stimuli during 7-12 Hz cortical oscillations in awake rats. 
  • Behavioral modulation of tactile responses in the rat somatosensory system. 
  • Behavioral properties of the trigeminal somatosensory system in rats performing whisker-dependent tactile discriminations. 
  • Beta Frequency Oscillations in the Subthalamic Nucleus Are Not Sufficient for the Development of Symptoms of Parkinsonian Bradykinesia/Akinesia in Rats. 
  • Bilateral integration of whisker information in the primary somatosensory cortex of rats. 
  • Blockade of NMDA receptors in the dorsomedial striatum prevents action-outcome learning in instrumental conditioning. 
  • Building an organic computing device with multiple interconnected brains. 
  • Bypassing the duodenum does not improve insulin resistance associated with diet-induced obesity in rodents. 
  • CNS glucagon-like peptide-1 receptors mediate endocrine and anxiety responses to interoceptive and psychogenic stressors. 
  • COG1410, an apolipoprotein E-based peptide, improves cognitive performance and reduces cortical loss following moderate fluid percussion injury in the rat. 
  • Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms. 
  • Cell type-specific changes in retinal ganglion cell function induced by rod death and cone reorganization in rats. 
  • Central Nervous System GLP-1 Receptors Regulate Islet Hormone Secretion and Glucose Homeostasis in Male Rats. 
  • Central infusion of glucagon-like peptide-1-(7-36) amide (GLP-1) receptor antagonist attenuates lithium chloride-induced c-Fos induction in rat brainstem. 
  • Characterizing effects of subthalamic nucleus deep brain stimulation on methamphetamine-induced circling behavior in hemi-Parkinsonian rats. 
  • Chronic spinal cord electrical stimulation protects against 6-hydroxydopamine lesions. 
  • Comparison of acute neurobehavioral and cholinesterase inhibitory effects of N-methylcarbamates in rat. 
  • Consumption of a high-fat diet induces central insulin resistance independent of adiposity. 
  • Contributions of striatal subregions to place and response learning. 
  • Coordination of Brain-Wide Activity Dynamics by Dopaminergic Neurons. 
  • Cortical Neuroprosthesis Merges Visible and Invisible Light Without Impairing Native Sensory Function. 
  • Cortical and thalamic contributions to response dynamics across layers of the primary somatosensory cortex during tactile discrimination. 
  • Deconstructing 5-HT6 receptor effects on striatal circuit function. 
  • Deep brain stimulation of the subthalamic nucleus reestablishes neuronal information transmission in the 6-OHDA rat model of parkinsonism. 
  • Developmental changes in seizure susceptibility during ethanol withdrawal. 
  • Dietary galactose inhibits GDF-9 mediated follicular development in the rat ovary. 
  • Differences in the central anorectic effects of glucagon-like peptide-1 and exendin-4 in rats. 
  • Differential LRRK2 expression in the cortex, striatum, and substantia nigra in transgenic and nontransgenic rodents. 
  • Differential effects of modulation of docosahexaenoic acid content during development in specific regions of rat brain. 
  • Disinhibition in rat superior colliculus mediated by GABAc receptors. 
  • Dissociable roles for the basolateral amygdala and orbitofrontal cortex in decision-making under risk of punishment. 
  • Distinct neural ensembles in the rat gustatory cortex encode salt and water tastes. 
  • Distribution of glucagon-like peptide-1 immunoreactivity in the hypothalamic paraventricular and supraoptic nuclei. 
  • Dopamine D1 receptors and phosphorylation of dopamine- and cyclic AMP-regulated phosphoprotein-32 in the medial preoptic area are involved in experience-induced enhancement of male sexual behavior in rats. 
  • Dose-sensitive excitation and inhibition of spontaneous amygdala activity by propranolol. 
  • Dynamic and multimodal responses of gustatory cortical neurons in awake rats. 
  • Effect of sub-chronic intermittent ethanol exposure on spatial learning and ethanol sensitivity in adolescent and adult rats. 
  • Effect of the isoflavone genistein against galactose-induced cataracts in rats. 
  • Effect of vertical sleeve gastrectomy on food selection and satiation in rats. 
  • Effective deep brain stimulation suppresses low-frequency network oscillations in the basal ganglia by regularizing neural firing patterns. 
  • Effects of a fixed meal pattern on ghrelin secretion: evidence for a learned response independent of nutrient status. 
  • Effects of acute normovolemic hemodilution on T2*-weighted images of rat brain. 
  • Effects of genistein or soy milk during late gestation and lactation on adult uterine organization in the rat. 
  • Embedding a Panoramic Representation of Infrared Light in the Adult Rat Somatosensory Cortex through a Sensory Neuroprosthesis. 
  • Encoding of tactile stimulus location by somatosensory thalamocortical ensembles. 
  • Enhanced retention in the passive-avoidance task by 5-HT(1A) receptor blockade is not associated with increased activity of the central nucleus of the amygdala. 
  • Esterase detoxication of acetylcholinesterase inhibitors using human liver samples in vitro. 
  • Esterase metabolism of cholinesterase inhibitors using rat liver in vitro. 
  • Ethanol inhibits spontaneous activity of central nucleus of the amygdala neurons but does not impair retention in the passive-avoidance task. 
  • Failure to suppress low-frequency neuronal oscillatory activity underlies the reduced effectiveness of random patterns of deep brain stimulation. 
  • Food intake-independent effects of CB1 antagonism on glucose and lipid metabolism. 
  • Frequency-dependent, transient effects of subthalamic nucleus deep brain stimulation on methamphetamine-induced circling and neuronal activity in the hemiparkinsonian rat. 
  • Functional electrical stimulation helps replenish progenitor cells in the injured spinal cord of adult rats. 
  • Further assessment of an in vitro screen that may help identify organophosphorus pesticides that are more acutely toxic to the young. 
  • GLP-1R agonism enhances adjustable gastric banding in diet-induced obese rats. 
  • GLP-1R responsiveness predicts individual gastric bypass efficacy on glucose tolerance in rats. 
  • Gastric acid and particulate aspiration injury inhibits pulmonary bacterial clearance. 
  • Genetic background influences LRRK2-mediated Rab phosphorylation in the rat brain. 
  • Gestational exposure to chlorpyrifos: apparent protection of the fetus? 
  • Gestational exposure to chlorpyrifos: comparative distribution of trichloropyridinol in the fetus and dam. 
  • Gestational exposure to chlorpyrifos: dose response profiles for cholinesterase and carboxylesterase activity. 
  • Ghrelin enhances olfactory sensitivity and exploratory sniffing in rodents and humans. 
  • Global forebrain dynamics predict rat behavioral states and their transitions. 
  • Heterogeneous integration of bilateral whisker signals by neurons in primary somatosensory cortex of awake rats. 
  • High-fat diet changes the temporal profile of GLP-1 receptor-mediated hypophagia in rats. 
  • Hyperphagia and increased fat accumulation in two models of chronic CNS glucagon-like peptide-1 loss of function. 
  • Ignoring correlated activity causes a failure of retinal population codes. 
  • Immediate thalamic sensory plasticity depends on corticothalamic feedback. 
  • Impact of chemical proportions on the acute neurotoxicity of a mixture of seven carbamates in preweanling and adult rats. 
  • Impact of intestinal electrical stimulation on nutrient-induced GLP-1 secretion in vivo. 
  • In vitro properties of neurons in the rat pretectal nucleus of the optic tract. 
  • Inactivation of dorsolateral striatum enhances sensitivity to changes in the action-outcome contingency in instrumental conditioning. 
  • Increased dietary fat attenuates the anorexic effects of intracerebroventricular injections of MTII. 
  • Increased expression of 5-HT₆ receptors in dorsolateral striatum decreases habitual lever pressing, but does not affect learning acquisition of simple operant tasks in rats. 
  • Increased expression of the 5-HT6 receptor by viral mediated gene transfer into posterior but not anterior dorsomedial striatum interferes with acquisition of a discrete action-outcome task. 
  • Inhibition of central amylin signaling increases food intake and body adiposity in rats. 
  • Insulin increases central apolipoprotein E levels as revealed by an improved technique for collection of cerebrospinal fluid from rats. 
  • Integration of bilateral whisker stimuli in rats: role of the whisker barrel cortices. 
  • Inter-mosaic coordination of retinal receptive fields. 
  • Intestinal adaptation after ileal interposition surgery increases bile acid recycling and protects against obesity-related comorbidities. 
  • Intravascular food reward. 
  • Layer-specific somatosensory cortical activation during active tactile discrimination. 
  • Lesions of dorsolateral striatum preserve outcome expectancy but disrupt habit formation in instrumental learning. 
  • Licking-induced synchrony in the taste-reward circuit improves cue discrimination during learning. 
  • Long-lasting novelty-induced neuronal reverberation during slow-wave sleep in multiple forebrain areas. 
  • Loop diuretics have anxiolytic effects in rat models of conditioned anxiety. 
  • Lysophosphatidic acid receptor signaling in mammalian retinal pigment epithelial cells. 
  • Massive light-driven translocation of transducin between the two major compartments of rod cells: a novel mechanism of light adaptation. 
  • Meal feeding improves oral glucose tolerance in male rats and causes adaptations in postprandial islet hormone secretion that are independent of plasma incretins or glycemia. 
  • Meal-anticipatory glucagon-like peptide-1 secretion in rats. 
  • Mechanisms of oleoylethanolamide-induced changes in feeding behavior and motor activity. 
  • Metabolic effects of dietary lactose in adult female rats. 
  • Model-based deconstruction of cortical evoked potentials generated by subthalamic nucleus deep brain stimulation. 
  • Neural ensemble coding of satiety states. 
  • Neurobehavioral effects of chronic dietary and repeated high-level spike exposure to chlorpyrifos in rats. 
  • Neurochemical effects of chronic dietary and repeated high-level acute exposure to chlorpyrifos in rats. 
  • Neuronal activity in the primary somatosensory thalamocortical loop is modulated by reward contingency during tactile discrimination. 
  • Neuronal ensemble bursting in the basal forebrain encodes salience irrespective of valence. 
  • Obesity induced by a high-fat diet downregulates apolipoprotein A-IV gene expression in rat hypothalamus. 
  • Ocular melanoma in a Long Evans rat. 
  • Optimized temporal pattern of brain stimulation designed by computational evolution. 
  • Orbitofrontal ensemble activity monitors licking and distinguishes among natural rewards. 
  • Ovarian effects of a high lactose diet in the female rat. 
  • Parallel Inhibitory and Excitatory Trigemino-Facial Feedback Circuitry for Reflexive Vibrissa Movement. 
  • Pathway-Specific Asymmetries between ON and OFF Visual Signals. 
  • Patterned low-frequency deep brain stimulation induces motor deficits and modulates cortex-basal ganglia neural activity in healthy rats. 
  • Perceiving invisible light through a somatosensory cortical prosthesis. 
  • Polycystic kidney disease as a result of loss of the tuberous sclerosis 2 tumor suppressor gene during development. 
  • Potential role of PTEN phosphatase in ethanol-impaired survival signaling in the liver. 
  • Principal component analysis of neuronal ensemble activity reveals multidimensional somatosensory representations. 
  • Processing of tactile information by the hippocampus. 
  • Promotion by sodium barbital induces early development but does not increase the multiplicity of hereditary renal tumors in Eker rats. 
  • Proteomic profiling of a layered tissue reveals unique glycolytic specializations of photoreceptor cells. 
  • Quantifying lipofuscin in retinal pigment epithelium in vivo by visible-light optical coherence tomography-based multimodal imaging. 
  • Quantitative magnetic resonance imaging in experimental hypercapnia: improvement in the relation between changes in brain R2 and the oxygen saturation of venous blood after correction for changes in cerebral blood volume. 
  • Rapid hepatic metabolism blunts the endocrine action of portally infused GLP-1 in male rats. 
  • Rapid taste responses in the gustatory cortex during licking. 
  • Real-time control of a robot arm using simultaneously recorded neurons in the motor cortex. 
  • Reduction of pentylenetetrazole-induced seizure activity in awake rats by seizure-triggered trigeminal nerve stimulation. 
  • Regulation of gastric emptying rate and its role in nutrient-induced GLP-1 secretion in rats after vertical sleeve gastrectomy. 
  • Reinforcer devaluation abolishes conditioned cue preference: evidence for stimulus-stimulus associations. 
  • Relationship between brain and plasma carbaryl levels and cholinesterase inhibition. 
  • Rescue of Methyl-CpG Binding Protein 2 Dysfunction-induced Defects in Newborn Neurons by Pentobarbital. 
  • Restricted expression of WT1 messenger ribonucleic acid in immature ovarian follicles: uniformity in mammalian and avian species and maintenance during reproductive senescence. 
  • Reversal of diet-induced obesity increases insulin transport into cerebrospinal fluid and restores sensitivity to the anorexic action of central insulin in male rats. 
  • Role of cortical feedback in the receptive field structure and nonlinear response properties of somatosensory thalamic neurons. 
  • Schizophrenia-like GABAergic gene expression deficits in cerebellar Golgi cells from rats chronically exposed to low-dose phencyclidine. 
  • Similar effects of roux-en-Y gastric bypass and vertical sleeve gastrectomy on glucose regulation in rats. 
  • Simultaneous reorganization in thalamocortical ensembles evolves over several hours after perioral capsaicin injections. 
  • Simultaneous top-down modulation of the primary somatosensory cortex and thalamic nuclei during active tactile discrimination. 
  • Spatiotemporal coupling between hippocampal acetylcholine release and theta oscillations in vivo. 
  • Spatiotemporal properties of layer V neurons of the rat primary somatosensory cortex. 
  • Spike avalanches exhibit universal dynamics across the sleep-wake cycle. 
  • Suppression of food intake by glucagon-like peptide-1 receptor agonists: relative potencies and role of dipeptidyl peptidase-4. 
  • Survival of adult rat retinal ganglion cells with regrown axons in peripheral nerve grafts: a comparison of graft attachment with suture of fibrin glue. 
  • Sustained functional improvement by hepatocyte growth factor-like small molecule BB3 after focal cerebral ischemia in rats and mice. 
  • Taste-guided decisions differentially engage neuronal ensembles across gustatory cortices. 
  • Taste-specific neuronal ensembles in the gustatory cortex of awake rats. 
  • The Role of Elevated Branched-Chain Amino Acids in the Effects of Vertical Sleeve Gastrectomy to Reduce Weight and Improve Glucose Regulation. 
  • The anorectic effect of GLP-1 in rats is nutrient dependent. 
  • The diverse roles of specific GLP-1 receptors in the control of food intake and the response to visceral illness. 
  • The effects of GLP-1 infusion in the hepatic portal region on food intake. 
  • The role of CNS glucagon-like peptide-1 (7-36) amide receptors in mediating the visceral illness effects of lithium chloride. 
  • The role of pedunculopontine nucleus in choice behavior under risk. 
  • The role of the dorsomedial striatum in instrumental conditioning. 
  • The role of ΔfosB in the medial preoptic area: Differential effects of mating and cocaine history. 
  • Time course of cholinesterase inhibition in adult rats treated acutely with carbaryl, carbofuran, formetanate, methomyl, methiocarb, oxamyl or propoxur. 
  • Transcranial magnetic stimulation induces current pulses in transcranial direct current stimulation electrodes. 
  • Transducin translocation in rods is triggered by saturation of the GTPase-activating complex. 
  • Upstream stimulatory factors are mediators of Ca2+-responsive transcription in neurons. 
  • Uterine leiomyoma in the Eker rat: a unique model for important diseases of women. 
  • Voluntary consumption of ethyl oleate reduces food intake and body weight in rats. 
  • Weight loss through ileal transposition is accompanied by increased ileal hormone secretion and synthesis in rats. 
  • Weight-independent changes in blood glucose homeostasis after gastric bypass or vertical sleeve gastrectomy in rats. 
  • siRNA inhibition of aspartyl-asparaginyl β-hydroxylase expression impairs cell motility, Notch signaling, and fetal growth. 
  • ΔN-TRPV1: A Molecular Co-detector of Body Temperature and Osmotic Stress. 
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  Keywords of People

  • Nicolelis, Miguel Angelo L., Duke School of Medicine Distinguished Professor in Neuroscience, Neurobiology