Interleukin-17
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Subject Areas on Research
- A Novel Mechanism for Th17 Inflammation in Human Type 2 Diabetes Mellitus.
- A Prognostic Model of Persistent Bacteremia and Mortality in Complicated Staphylococcus aureus Bloodstream Infection.
- A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303.
- Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition.
- Altered balance between Th17 and Th1 cells at mucosal sites predicts AIDS progression in simian immunodeficiency virus-infected macaques.
- Associations of genotypes and haplotypes of IL-17 with risk of gastric cancer in an eastern Chinese population.
- Augmented Responses to Ozone in Obese Mice Require IL-17A and Gastrin-Releasing Peptide.
- Autoimmunity in dry eye is due to resistance of Th17 to Treg suppression.
- B cell depletion reduces the development of atherosclerosis in mice.
- Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model.
- Circulating Mucosal-Associated Invariant T Cells in a Large Cohort of Healthy Chinese Individuals From Newborn to Elderly.
- Cutting edge: ABIN-1 protects against psoriasis by restricting MyD88 signals in dendritic cells.
- Degenerate TCR recognition and dual DR2 restriction of autoreactive T cells: implications for the initiation of the autoimmune response in multiple sclerosis.
- Dendritic epidermal T cells regulate skin antimicrobial barrier function.
- Diacylglycerol kinase zeta positively controls the development of iNKT-17 cells.
- Differential Role of B Cells and IL-17 Versus IFN-γ During Early and Late Rejection of Pig Islet Xenografts in Mice.
- Differential requirement of RasGRP1 for γδ T cell development and activation.
- Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity.
- Dominant gain-of-function STAT1 mutations in FOXP3 wild-type immune dysregulation-polyendocrinopathy-enteropathy-X-linked-like syndrome.
- Dynamics of Circulating γδ T Cell Activity in an Immunocompetent Mouse Model of High-Grade Glioma.
- ERα Signaling Increased IL-17A Production in Th17 Cells by Upregulating IL-23R Expression, Mitochondrial Respiration, and Proliferation.
- Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin.
- Enhanced Th17-cell responses render CCR2-deficient mice more susceptible for autoimmune arthritis.
- Epigenetic instability of cytokine and transcription factor gene loci underlies plasticity of the T helper 17 cell lineage.
- Filaggrin deficiency promotes the dissemination of cutaneously inoculated vaccinia virus.
- G-CSF induces a potentially tolerant gene and immunophenotype profile in T cells in vivo.
- IFN-beta inhibits human Th17 cell differentiation.
- IFN-beta1a inhibits the secretion of Th17-polarizing cytokines in human dendritic cells via TLR7 up-regulation.
- IL-11 Induces Encephalitogenic Th17 Cells in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis.
- IL-11 Induces Th17 Cell Responses in Patients with Early Relapsing-Remitting Multiple Sclerosis.
- IL-17 Production of Neutrophils Enhances Antibacteria Ability but Promotes Arthritis Development During Mycobacterium tuberculosis Infection.
- IL-17 contributes to neutrophil recruitment but not to control of viral replication during acute mouse adenovirus type 1 respiratory infection.
- IL-17A Contributes to Lung Fibrosis in a Model of Chronic Pulmonary Graft-versus-host Disease.
- IL-17A Contributes to the Pathogenesis of Endometriosis by Triggering Proinflammatory Cytokines and Angiogenic Growth Factors.
- IL-1R signaling promotes STAT3 and NF-κB factor recruitment to distal cis-regulatory elements that regulate Il17a/f transcription.
- IL-1β-dependent activation of dendritic epidermal T cells in contact hypersensitivity.
- IL-23 Enhances C-Fiber-Mediated and Blue Light-Induced Spontaneous Pain in Female Mice.
- IL-23/IL-17A/TRPV1 axis produces mechanical pain via macrophage-sensory neuron crosstalk in female mice.
- Identification of potential cytokine pathways for therapeutic intervention in murine primary biliary cirrhosis.
- Imbalance in T follicular helper cells producing IL-17 promotes pro-inflammatory responses in MuSK antibody positive myasthenia gravis.
- Immunological and short-term brain volume changes in relapsing forms of multiple sclerosis treated with interferon beta-1a subcutaneously three times weekly: an open-label two-arm trial.
- In pursuit of new experimental models of obliterative bronchiolitis.
- Infection with Francisella tularensis LVS clpB leads to an altered yet protective immune response.
- Inflammation Gets on the Lung's Nerves: IL-17 and Neuroendocrine Cells Mediate Ozone Responses in Obesity.
- Inflammatory Th1 and Th17 in the Intestine Are Each Driven by Functionally Specialized Dendritic Cells with Distinct Requirements for MyD88.
- Inhibition of the transcription factor ROR-γ reduces pathogenic Th17 cells in acetylcholine receptor antibody positive myasthenia gravis.
- Interactions between gut microbiota and metabolites modulate cytokine network imbalances in women with unexplained miscarriage.
- Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice.
- Interleukin-1, tumor necrosis factor alpha, and interleukin-17 synergistically up-regulate nitric oxide and prostaglandin E2 production in explants of human osteoarthritic knee menisci.
- Interleukin-17 synergizes with IFNγ or TNFα to promote inflammatory mediator release and intercellular adhesion molecule-1 (ICAM-1) expression in human intervertebral disc cells.
- Interleukin-17A Contributes to the Control of Streptococcus pyogenes Colonization and Inflammation of the Female Genital Tract.
- JunB promotes Th17 cell identity and restrains alternative CD4+ T-cell programs during inflammation.
- Malignancy Risk and Recurrence with Psoriasis and its Treatments: A Concise Update.
- Microbially driven TLR5-dependent signaling governs distal malignant progression through tumor-promoting inflammation.
- Mnk1 and 2 are dispensable for T cell development and activation but important for the pathogenesis of experimental autoimmune encephalomyelitis.
- Mouse adenovirus type 1 infection of adipose tissue.
- Multifactorial Design of a Supramolecular Peptide Anti-IL-17 Vaccine Toward the Treatment of Psoriasis.
- Mycobacterium bovis bacille Calmette-Guérin infection in the CNS suppresses experimental autoimmune encephalomyelitis and Th17 responses in an IFN-gamma-independent manner.
- Natural and inducible TH17 cells are regulated differently by Akt and mTOR pathways.
- Nucleosome in patients with systemic sclerosis: possible association with immunological abnormalities via abnormal activation of T and B cells.
- Oligoclonal myelin-reactive T-cell infiltrates derived from multiple sclerosis lesions are enriched in Th17 cells.
- PD-1/PD-L1, but not PD-1/PD-L2, interactions regulate the severity of experimental autoimmune encephalomyelitis.
- Peripheral blood cytokine and chemokine profiles in juvenile localized scleroderma: T-helper cell-associated cytokine profiles.
- Prevention and treatment of diabetes with resveratrol in a non-obese mouse model of type 1 diabetes.
- Proinflammatory cytokine expression profile in degenerated and herniated human intervertebral disc tissues.
- Protective immunity in recurrent Staphylococcus aureus infection reflects localized immune signatures and macrophage-conferred memory.
- Recovery of interleukin-17 production from interleukin-15-stimulated CD4+ mononuclear cells in HIV-1-infected patients with sustained viral suppression.
- Regulation of T-helper-cell lineage development by osteopontin: the inside story.
- Regulatory B cells suppress imiquimod-induced, psoriasis-like skin inflammation.
- Regulatory T cells attenuate Th17 cell-mediated nigrostriatal dopaminergic neurodegeneration in a model of Parkinson's disease.
- Role of complement activation in obliterative bronchiolitis post-lung transplantation.
- Safety and immunologic effects of high- vs low-dose cholecalciferol in multiple sclerosis.
- Scavenger Receptor BI Attenuates IL-17A-Dependent Neutrophilic Inflammation in Asthma.
- Secukinumab (AIN-457) for the treatment of Psoriasis.
- Simvastatin inhibits IL-17 secretion by targeting multiple IL-17-regulatory cytokines and by inhibiting the expression of IL-17 transcription factor RORC in CD4+ lymphocytes.
- Skin-resident T cells sense ultraviolet radiation-induced injury and contribute to DNA repair.
- Statins' immunomodulatory potential against Th17 cell-mediated autoimmune response.
- Synthesis and Biological Evaluation of Subglutinol Analogs for Immunomodulatory Agents.
- T Cell Receptor-Independent, CD31/IL-17A-Driven Inflammatory Axis Shapes Synovitis in Juvenile Idiopathic Arthritis.
- T helper subsets in allergic eye disease.
- T reg cell-intrinsic requirements for ST2 signaling in health and neuroinflammation.
- T-lymphocytes enable osteoblast maturation via IL-17F during the early phase of fracture repair.
- TNF-α in T lymphocytes attenuates renal injury and fibrosis during nephrotoxic nephritis.
- Targeting Histone Deacetylase 6 Reprograms Interleukin-17-Producing Helper T Cell Pathogenicity and Facilitates Immunotherapies for Hepatocellular Carcinoma.
- The m6A reader IMP2 directs autoimmune inflammation through an IL-17- and TNFα-dependent C/EBP transcription factor axis.
- The molecular pathogenesis of STAT3-driven gastric tumourigenesis in mice is independent of IL-17.
- The prognostic value of interleukin-17 in lung cancer: A systematic review with meta-analysis based on Chinese patients.
- The transcription factor c-Maf is essential for the commitment of IL-17-producing γδ T cells.
- Therapeutic Effect of Anti-CD52 Monoclonal Antibody in Multiple Sclerosis and Its Animal Models Is Mediated via T Regulatory Cells.
- Thyroid Autoimmune Antibodies and Major Depressive Disorder in Women.
- Tγδ17 cells build up the nerve.
- Unrelated immunodeficiency states may impact outcomes and immune checkpoint molecule expression in patients with mycosis fungoides: A clinicopathologic case-control study.
- Vitamin D analogs differentially control antimicrobial peptide/"alarmin" expression in psoriasis.
- iNKT cells require TSC1 for terminal maturation and effector lineage fate decisions.
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Keywords of People
- Shinohara, Mari L., Associate Professor of Immunology, Cell Biology
- Zhong, Xiaoping, Professor of Pediatrics, Immunology