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Subject Areas on Research
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A Novel Mechanism for Th17 Inflammation in Human Type 2 Diabetes Mellitus.
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A Prognostic Model of Persistent Bacteremia and Mortality in Complicated Staphylococcus aureus Bloodstream Infection.
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A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303.
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Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition.
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Altered balance between Th17 and Th1 cells at mucosal sites predicts AIDS progression in simian immunodeficiency virus-infected macaques.
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Associations of genotypes and haplotypes of IL-17 with risk of gastric cancer in an eastern Chinese population.
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Augmented Responses to Ozone in Obese Mice Require IL-17A and Gastrin-Releasing Peptide.
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Autoimmunity in dry eye is due to resistance of Th17 to Treg suppression.
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B cell depletion reduces the development of atherosclerosis in mice.
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Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model.
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Circulating Mucosal-Associated Invariant T Cells in a Large Cohort of Healthy Chinese Individuals From Newborn to Elderly.
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Cutting edge: ABIN-1 protects against psoriasis by restricting MyD88 signals in dendritic cells.
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Degenerate TCR recognition and dual DR2 restriction of autoreactive T cells: implications for the initiation of the autoimmune response in multiple sclerosis.
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Dendritic epidermal T cells regulate skin antimicrobial barrier function.
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Diacylglycerol kinase zeta positively controls the development of iNKT-17 cells.
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Differential Role of B Cells and IL-17 Versus IFN-γ During Early and Late Rejection of Pig Islet Xenografts in Mice.
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Differential requirement of RasGRP1 for γδ T cell development and activation.
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Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity.
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Dominant gain-of-function STAT1 mutations in FOXP3 wild-type immune dysregulation-polyendocrinopathy-enteropathy-X-linked-like syndrome.
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Dynamics of Circulating γδ T Cell Activity in an Immunocompetent Mouse Model of High-Grade Glioma.
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ERα Signaling Increased IL-17A Production in Th17 Cells by Upregulating IL-23R Expression, Mitochondrial Respiration, and Proliferation.
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Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin.
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Enhanced Th17-cell responses render CCR2-deficient mice more susceptible for autoimmune arthritis.
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Epigenetic instability of cytokine and transcription factor gene loci underlies plasticity of the T helper 17 cell lineage.
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IFN-beta inhibits human Th17 cell differentiation.
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IFN-beta1a inhibits the secretion of Th17-polarizing cytokines in human dendritic cells via TLR7 up-regulation.
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IFN-γ, but not IL-17A, is required for survival during secondary pulmonary Francisella tularensis Live Vaccine Stain infection.
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IL-11 Induces Encephalitogenic Th17 Cells in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis.
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IL-11 Induces Th17 Cell Responses in Patients with Early Relapsing-Remitting Multiple Sclerosis.
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IL-17 Production of Neutrophils Enhances Antibacteria Ability but Promotes Arthritis Development During Mycobacterium tuberculosis Infection.
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IL-17A Contributes to Lung Fibrosis in a Model of Chronic Pulmonary Graft-versus-host Disease.
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IL-1R signaling promotes STAT3 and NF-κB factor recruitment to distal cis-regulatory elements that regulate Il17a/f transcription.
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IL-1β-dependent activation of dendritic epidermal T cells in contact hypersensitivity.
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IL-23 Enhances C-Fiber-Mediated and Blue Light-Induced Spontaneous Pain in Female Mice.
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IL-23/IL-17A/TRPV1 axis produces mechanical pain via macrophage-sensory neuron crosstalk in female mice.
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Identification of potential cytokine pathways for therapeutic intervention in murine primary biliary cirrhosis.
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Imbalance in T follicular helper cells producing IL-17 promotes pro-inflammatory responses in MuSK antibody positive myasthenia gravis.
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Immunological and short-term brain volume changes in relapsing forms of multiple sclerosis treated with interferon beta-1a subcutaneously three times weekly: an open-label two-arm trial.
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In pursuit of new experimental models of obliterative bronchiolitis.
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Infection with Francisella tularensis LVS clpB leads to an altered yet protective immune response.
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Inflammation Gets on the Lung's Nerves: IL-17 and Neuroendocrine Cells Mediate Ozone Responses in Obesity.
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Inflammatory Th1 and Th17 in the Intestine Are Each Driven by Functionally Specialized Dendritic Cells with Distinct Requirements for MyD88.
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Inhibition of the transcription factor ROR-γ reduces pathogenic Th17 cells in acetylcholine receptor antibody positive myasthenia gravis.
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Interactions between gut microbiota and metabolites modulate cytokine network imbalances in women with unexplained miscarriage.
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Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice.
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Interleukin-1, tumor necrosis factor alpha, and interleukin-17 synergistically up-regulate nitric oxide and prostaglandin E2 production in explants of human osteoarthritic knee menisci.
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Interleukin-17 synergizes with IFNγ or TNFα to promote inflammatory mediator release and intercellular adhesion molecule-1 (ICAM-1) expression in human intervertebral disc cells.
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JunB promotes Th17 cell identity and restrains alternative CD4+ T-cell programs during inflammation.
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Mnk1 and 2 are dispensable for T cell development and activation but important for the pathogenesis of experimental autoimmune encephalomyelitis.
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Multifactorial Design of a Supramolecular Peptide Anti-IL-17 Vaccine Toward the Treatment of Psoriasis.
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Mycobacterium bovis bacille Calmette-Guérin infection in the CNS suppresses experimental autoimmune encephalomyelitis and Th17 responses in an IFN-gamma-independent manner.
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Natural and inducible TH17 cells are regulated differently by Akt and mTOR pathways.
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Nucleosome in patients with systemic sclerosis: possible association with immunological abnormalities via abnormal activation of T and B cells.
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Oligoclonal myelin-reactive T-cell infiltrates derived from multiple sclerosis lesions are enriched in Th17 cells.
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PD-1/PD-L1, but not PD-1/PD-L2, interactions regulate the severity of experimental autoimmune encephalomyelitis.
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Peripheral blood cytokine and chemokine profiles in juvenile localized scleroderma: T-helper cell-associated cytokine profiles.
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Prevention and treatment of diabetes with resveratrol in a non-obese mouse model of type 1 diabetes.
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Proinflammatory cytokine expression profile in degenerated and herniated human intervertebral disc tissues.
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Protective immunity in recurrent Staphylococcus aureus infection reflects localized immune signatures and macrophage-conferred memory.
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Recovery of interleukin-17 production from interleukin-15-stimulated CD4+ mononuclear cells in HIV-1-infected patients with sustained viral suppression.
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Regulation of T-helper-cell lineage development by osteopontin: the inside story.
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Regulatory B cells suppress imiquimod-induced, psoriasis-like skin inflammation.
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Regulatory T cells attenuate Th17 cell-mediated nigrostriatal dopaminergic neurodegeneration in a model of Parkinson's disease.
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Role of complement activation in obliterative bronchiolitis post-lung transplantation.
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Safety and immunologic effects of high- vs low-dose cholecalciferol in multiple sclerosis.
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Scavenger Receptor BI Attenuates IL-17A-Dependent Neutrophilic Inflammation in Asthma.
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Secukinumab (AIN-457) for the treatment of Psoriasis.
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Simvastatin inhibits IL-17 secretion by targeting multiple IL-17-regulatory cytokines and by inhibiting the expression of IL-17 transcription factor RORC in CD4+ lymphocytes.
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Skin-resident T cells sense ultraviolet radiation-induced injury and contribute to DNA repair.
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Statins' immunomodulatory potential against Th17 cell-mediated autoimmune response.
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Synthesis and Biological Evaluation of Subglutinol Analogs for Immunomodulatory Agents.
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T Cell Receptor-Independent, CD31/IL-17A-Driven Inflammatory Axis Shapes Synovitis in Juvenile Idiopathic Arthritis.
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T helper subsets in allergic eye disease.
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T reg cell-intrinsic requirements for ST2 signaling in health and neuroinflammation.
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T-lymphocytes enable osteoblast maturation via IL-17F during the early phase of fracture repair.
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TNF-α in T lymphocytes attenuates renal injury and fibrosis during nephrotoxic nephritis.
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Targeting Histone Deacetylase 6 Reprograms Interleukin-17-Producing Helper T Cell Pathogenicity and Facilitates Immunotherapies for Hepatocellular Carcinoma.
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The m6A reader IMP2 directs autoimmune inflammation through an IL-17- and TNFα-dependent C/EBP transcription factor axis.
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The prognostic value of interleukin-17 in lung cancer: A systematic review with meta-analysis based on Chinese patients.
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The transcription factor c-Maf is essential for the commitment of IL-17-producing γδ T cells.
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Thyroid Autoimmune Antibodies and Major Depressive Disorder in Women.
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Tγδ17 cells build up the nerve.
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Vitamin D analogs differentially control antimicrobial peptide/"alarmin" expression in psoriasis.
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iNKT cells require TSC1 for terminal maturation and effector lineage fate decisions.
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Keywords of People