Molecular Motor Proteins
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Subject Areas on Research
- A microtubule-destabilizing kinesin motor regulates spindle length and anchoring in oocytes.
- A mutant of the motor protein kinesin that moves in both directions on microtubules.
- A new kinesin tree.
- A new structural state of myosin.
- A structural pathway for activation of the kinesin motor ATPase.
- A two-tiered mechanism by which Cdc42 controls the localization and activation of an Arp2/3-activating motor complex in yeast.
- A unidirectional DNA walker that moves autonomously along a track.
- APOL1 variants increase risk for FSGS and HIVAN but not IgA nephropathy.
- An MYH9 human disease model in flies: site-directed mutagenesis of the Drosophila non-muscle myosin II results in hypomorphic alleles with dominant character.
- Angiotensin-II mediates nonmuscle myosin II activation and expression and contributes to human keloid disease progression.
- Arrestin translocation is induced at a critical threshold of visual signaling and is superstoichiometric to bleached rhodopsin.
- Assembly pathway of the anastral Drosophila oocyte meiosis I spindle.
- Asymmetric division: AGS proteins position the spindle.
- B-cyclin/CDKs regulate mitotic spindle assembly by phosphorylating kinesins-5 in budding yeast.
- Beta-arrestin-mediated localization of smoothened to the primary cilium.
- Control of a biomolecular motor-powered nanodevice with an engineered chemical switch.
- Decoupling of nucleotide- and microtubule-binding sites in a kinesin mutant.
- Determinants of molecular motor directionality.
- Direct involvement of yeast type I myosins in Cdc42-dependent actin polymerization.
- Directionality and processivity of molecular motors.
- Evidence for an electrostatic mechanism of force generation by the bacteriophage T4 DNA packaging motor.
- Force generation by kinesin and myosin cytoskeletal motor proteins.
- Genomic sequencing-based mutational enrichment analysis identifies motility genes in a genetically intractable gut microbe.
- Genotype-phenotype correlation in MYH9-related thrombocytopenia.
- Green fluorescent protein as a tag for molecular motor proteins.
- Human nonsyndromic hereditary deafness DFNA17 is due to a mutation in nonmuscle myosin MYH9.
- In vivo Modeling Implicates APOL1 in Nephropathy: Evidence for Dominant Negative Effects and Epistasis under Anemic Stress.
- Kinesin motors as molecular machines.
- Kinesin: switch I & II and the motor mechanism.
- Kinesins at a glance.
- Light-driven translocation of signaling proteins in vertebrate photoreceptors.
- MYH9 and APOL1 are both associated with sickle cell disease nephropathy.
- Molecular motors--a paradigm for mutant analysis.
- Mutation of MYH9, encoding non-muscle myosin heavy chain A, in May-Hegglin anomaly.
- Myosin I contributes to the generation of resting cortical tension.
- Myosin head configuration in relaxed insect flight muscle: x-ray modeled resting cross-bridges in a pre-powerstroke state are poised for actin binding.
- On the Functional Role of Valve Interstitial Cell Stress Fibers: A Continuum Modeling Approach.
- Potential donor-recipient MYH9 genotype interactions in posttransplant nephrotic syndrome after pediatric kidney transplantation.
- Processive and nonprocessive models of kinesin movement.
- Rapid double 8-nm steps by a kinesin mutant.
- Report of a young girl with MYH9 mutation and review of the literature.
- Similarities and differences between frozen-hydrated, rigor acto-S1 complexes of insect flight and chicken skeletal muscles.
- Structural biology of plasmid partition: uncovering the molecular mechanisms of DNA segregation.
- The Drosophila centrosomal protein Nuf is required for recruiting Dah, a membrane associated protein, to furrows in the early embryo.
- The ciliopathies: an emerging class of human genetic disorders.
- The minus end-directed motor Kar3 is required for coupling dynamic microtubule plus ends to the cortical shmoo tip in budding yeast.