Photoreceptor Cells, Vertebrate
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Subject Areas on Research
- A novel method for comparative analysis of retinal specialization traits from topographic maps.
- Absence of the RGS9.Gbeta5 GTPase-activating complex in photoreceptors of the R9AP knockout mouse.
- Activation of Rod Input in a Model of Retinal Degeneration Reverses Retinal Remodeling and Induces Formation of Functional Synapses and Recovery of Visual Signaling in the Adult Retina.
- Antisense oligonucleotides targeting mutant Ataxin-7 restore visual function in a mouse model of spinocerebellar ataxia type 7.
- Beyond counting photons: trials and trends in vertebrate visual transduction.
- Biology and functions of the RGS9 isoforms.
- Cell death in age-related macular degeneration.
- Clinicopathologic studies of eyes that were obtained postmortem from four patients who were enrolled in the submacular surgery trials: SST Report No. 16.
- Comprehensive identification of mRNA isoforms reveals the diversity of neural cell-surface molecules with roles in retinal development and disease.
- Defects in RGS9 or its anchor protein R9AP in patients with slow photoreceptor deactivation.
- Defining the human macula transcriptome and candidate retinal disease genes using EyeSAGE.
- Disease expression of RP1 mutations causing autosomal dominant retinitis pigmentosa.
- Disrupted Blood-Retina Lysophosphatidylcholine Transport Impairs Photoreceptor Health But Not Visual Signal Transduction.
- Diurnal changes in exocytosis and the number of synaptic ribbons at active zones of an ON-type bipolar cell terminal.
- Dominant late-onset retinal degeneration with regional variation of sub-retinal pigment epithelium deposits, retinal function, and photoreceptor degeneration.
- Downregulation of a unique photoreceptor protein correlates with improper outer segment assembly.
- Ectopic synaptogenesis during retinal degeneration in the royal college of surgeons rat.
- Effect of Ciliary Neurotrophic Factor on Retinal Neurodegeneration in Patients with Macular Telangiectasia Type 2: A Randomized Clinical Trial.
- Elovl4 5-bp-deletion knock-in mice develop progressive photoreceptor degeneration.
- Enhanced transduction and improved photoreceptor survival of retinal degeneration by the combinatorial use of rAAV2 with a lower dose of adenovirus.
- Extraocular, Non-Visual, and Simple Photoreceptors: An Introduction to the Symposium.
- Ferroxidase hephaestin's cell-autonomous role in the retinal pigment epithelium.
- Functional comparison of RGS9 splice isoforms in a living cell.
- Fundus albipunctatus in a 6-year old girl due to compound heterozygous mutations in the RDH5 gene.
- Gene therapy for leber congenital amaurosis caused by RPE65 mutations: safety and efficacy in 15 children and adults followed up to 3 years.
- Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons.
- Impact of Heparan Sulfate Binding on Transduction of Retina by Recombinant Adeno-Associated Virus Vectors.
- Impaired monocyte cholesterol clearance initiates age-related retinal degeneration and vision loss.
- Interleukin-6 as a photoreceptor neuroprotectant in an experimental model of retinal detachment.
- Lensectomy and vitrectomy decrease the rate of photoreceptor loss in rhodopsin P347L transgenic pigs.
- Light-dependent magnetoreception: quantum catches and opponency mechanisms of possible photosensitive molecules.
- Light-driven translocation of signaling proteins in vertebrate photoreceptors.
- MEGF10 and MEGF11 mediate homotypic interactions required for mosaic spacing of retinal neurons.
- Male germ cells and photoreceptors, both dependent on close cell-cell interactions, degenerate upon ClC-2 Cl(-) channel disruption.
- Maturation of the human fovea: correlation of spectral-domain optical coherence tomography findings with histology.
- Membrane attachment is key to protecting transducin GTPase-activating complex from intracellular proteolysis in photoreceptors.
- Modelling colour constancy in fish: implications for vision and signalling in water.
- Multifocal electroretinogram in rhodopsin P347L transgenic pigs.
- Novel hybrid action of GABA mediates inhibitory feedback in the mammalian retina.
- Optical coherence tomography of choroidal osteoma in 22 cases: evidence for photoreceptor atrophy over the decalcified portion of the tumor.
- Peripapillary chorioretinal atrophy: Bruch's membrane changes and photoreceptor loss.
- Phenotypic stability of Pro347Leu rhodopsin transgenic pigs as indicated by photoreceptor cell degeneration.
- Phosducin regulates transmission at the photoreceptor-to-ON-bipolar cell synapse.
- Photoreceptor layer thinning over drusen in eyes with age-related macular degeneration imaged in vivo with spectral-domain optical coherence tomography.
- Photoreceptor light adaptation. Untangling desensitization and sensitization.
- Photoreceptor loss overlying congenital hypertrophy of the retinal pigment epithelium by optical coherence tomography.
- Photoreceptor signaling: supporting vision across a wide range of light intensities.
- Photoreceptors in a mouse model of Leigh syndrome are capable of normal light-evoked signaling.
- Pigment epithelium-derived factor supports normal development of photoreceptor neurons and opsin expression after retinal pigment epithelium removal.
- Progressive Rod-Cone Degeneration (PRCD) Protein Requires N-Terminal S-Acylation and Rhodopsin Binding for Photoreceptor Outer Segment Localization and Maintaining Intracellular Stability.
- Protein sorting, targeting and trafficking in photoreceptor cells.
- Protein translocation in photoreceptor light adaptation: a common theme in vertebrate and invertebrate vision.
- Proteomic profiling of a layered tissue reveals unique glycolytic specializations of photoreceptor cells.
- RPGR isoforms in photoreceptor connecting cilia and the transitional zone of motile cilia.
- Regulated heat shock protein 27 expression in human retinal pigment epithelium.
- Role of mouse cryptochrome blue-light photoreceptor in circadian photoresponses.
- Role of the Fas-signaling pathway in photoreceptor neuroprotection.
- Species-specific subcellular localization of RPGR and RPGRIP isoforms: implications for the phenotypic variability of congenital retinopathies among species.
- Specific binding of RGS9-Gbeta 5L to protein anchor in photoreceptor membranes greatly enhances its catalytic activity.
- Spectral domain optical coherence tomography imaging of geographic atrophy margins.
- Systemic administration of the iron chelator deferiprone protects against light-induced photoreceptor degeneration in the mouse retina.
- Targeted inactivation of synaptic HRG4 (UNC119) causes dysfunction in the distal photoreceptor and slow retinal degeneration, revealing a new function.
- The effector enzyme regulates the duration of G protein signaling in vertebrate photoreceptors by increasing the affinity between transducin and RGS protein.
- The relationship between slow photoresponse recovery rate and temporal resolution of vision.
- Timing is everything: GTPase regulation in phototransduction.
- Transplantation of full-thickness retina in the rhodopsin transgenic pig.
- Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2).
- Why do mutations in the ubiquitously expressed housekeeping gene IMPDH1 cause retina-specific photoreceptor degeneration?
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Keywords of People
- Farsiu, Sina, Professor in the Department of Biomedical Engineering, Electrical and Computer Engineering
- Stinnett, Sandra Sue, Associate Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics
- Toth, Cynthia Ann, Joseph A.C. Wadsworth Distinguished Professor of Ophthalmology, Biomedical Engineering