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Subject Areas on Research
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A Heat Shock Protein 48 (HSP48) Biomolecular Condensate Is Induced during Dictyostelium discoideum Development.
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A mass spectrometry-based proteomic approach to study Marek's Disease Virus gene expression.
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A novel interface for variable flow nanoscale LC/MS/MS for improved proteome coverage.
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A proteogenomic survey of the Medicago truncatula genome.
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A proteomic analysis of human cilia: identification of novel components.
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A proteomics approach to the identification of mammalian mitochondrial small subunit ribosomal proteins.
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A quantitative map of the liver mitochondrial phosphoproteome reveals posttranslational control of ketogenesis.
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Adhesion GPCR Latrophilin 3 regulates synaptic function of cone photoreceptors in a trans-synaptic manner.
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An array of 60,000 antibodies for proteome-scale antibody generation and target discovery.
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An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.
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An inducible heat shock protein 70 small molecule inhibitor demonstrates anti-dengue virus activity, validating Hsp70 as a host antiviral target.
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An overview of lung cancer genomics and proteomics.
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Analysis of "old" proteins unmasks dynamic gradient of cartilage turnover in human limbs.
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Analysis of copper-induced protein precipitation across the E. coli proteome.
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Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
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Application of a label-free, gel-free quantitative proteomics method for ecotoxicological studies of small fish species.
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Arabidopsis functional genomics.
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Bayesian analysis of signaling networks governing embryonic stem cell fate decisions.
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Benchmarking of dynamic Bayesian networks inferred from stochastic time-series data.
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Biomarkers and proteomic analysis of osteoarthritis.
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Building pathway clusters from Random Forests classification using class votes.
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Cancer immunotherapy with recombinant poliovirus induces IFN-dominant activation of dendritic cells and tumor antigen-specific CTLs.
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Cardiovascular Metabolomics.
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Cell surface glycoproteomic analysis of prostate cancer-derived PC-3 cells.
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Cerebrospinal Fluid Proteome Changes in Older Non-Cardiac Surgical Patients with Postoperative Cognitive Dysfunction.
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Changes in the Adult GluN2B Associated Proteome following Adolescent Intermittent Ethanol Exposure.
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Characterization of the ubiquitin-modified proteome regulated by transient forebrain ischemia.
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Chemico-genetic discovery of astrocytic control of inhibition in vivo.
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Chlamydia trachomatis Infection Leads to Defined Alterations to the Lipid Droplet Proteome in Epithelial Cells.
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Comparative Analysis of Mass-Spectrometry-Based Proteomic Methods for Protein Target Discovery Using a One-Pot Approach.
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Comparative Analysis of Protein Folding Stability-Based Profiling Methods for Characterization of Biological Phenotypes.
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Comparative proteomic analysis of differentially expressed proteins in β-aminobutyric acid enhanced Arabidopsis thaliana tolerance to simulated acid rain.
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Comparative proteomic analysis of proteins in response to simulated acid rain in Arabidopsis.
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Comparing human pancreatic cell secretomes by in vitro aptamer selection identifies cyclophilin B as a candidate pancreatic cancer biomarker.
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Comparison of Human Tissue Microarray to Human Pericyte Transcriptome Yields Novel Perivascular Cell Markers.
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Comparison of proteomic and metabolomic profiles of mutants of the mitochondrial respiratory chain in Caenorhabditis elegans.
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Comprehensive molecular characterization of gastric adenocarcinoma.
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Connecting genetic risk to disease end points through the human blood plasma proteome.
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Contribution of plasma cells and B cells to hidradenitis suppurativa pathogenesis.
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Defective innate immunity and hyperinflammation in newborn cystic fibrosis transmembrane conductance regulator-knockout ferret lungs.
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Delineating signal transduction pathways in smooth muscle through focused proteomics.
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Detecting Cardiovascular Protein-Protein Interactions by Proximity Proteomics.
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Determination of an angiotensin II-regulated proteome in primary human kidney cells by stable isotope labeling of amino acids in cell culture (SILAC).
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Differential extraction and enrichment of human sperm surface proteins in a proteome: identification of immunocontraceptive candidates.
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Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers.
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Discovery of Age-Related Protein Folding Stability Differences in the Mouse Brain Proteome.
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Discovery of Tamoxifen and N-Desmethyl Tamoxifen Protein Targets in MCF-7 Cells Using Large-Scale Protein Folding and Stability Measurements.
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Discovery of novel targets of quinoline drugs in the human purine binding proteome.
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Discovery of the Xenon-Protein Interactome Using Large-Scale Measurements of Protein Folding and Stability.
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Disruption of Acetyl-Lysine Turnover in Muscle Mitochondria Promotes Insulin Resistance and Redox Stress without Overt Respiratory Dysfunction.
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Dynamic evolution of base composition: causes and consequences in avian phylogenomics.
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Elucidating the Molecular Composition of Cartilage by Proteomics.
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Endosomal cAMP production broadly impacts the cellular phosphoproteome.
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Evaluation of serum protein profiling by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry for the detection of prostate cancer: I. Assessment of platform reproducibility.
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Evolution of budding yeast prion-determinant sequences across diverse fungi.
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Evolutionary Divergence of Gene and Protein Expression in the Brains of Humans and Chimpanzees.
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Exosome markers associated with immune activation and oxidative stress in HIV patients on antiretroviral therapy.
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Expanding the functional repertoire of CTD kinase I and RNA polymerase II: novel phosphoCTD-associating proteins in the yeast proteome.
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Exploiting the complementary nature of LC/MALDI/MS/MS and LC/ESI/MS/MS for increased proteome coverage.
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Exploring the mechanism of Physcomitrella patens desiccation tolerance through a proteomic strategy.
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Extreme Acetylation of the Cardiac Mitochondrial Proteome Does Not Promote Heart Failure.
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Frequency-dependent response of the vascular endothelium to pulsatile shear stress.
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G Protein-Coupled Receptor Endocytosis Confers Uniformity in Responses to Chemically Distinct Ligands.
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General olfactory sensitivity database (GOSdb): candidate genes and their genomic variations.
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Genetic disruption of WASHC4 drives endo-lysosomal dysfunction and cognitive-movement impairments in mice and humans.
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Genomic analysis of human lung fibroblasts exposed to vanadium pentoxide to identify candidate genes for occupational bronchitis.
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Genomic insights into the atopic eczema-associated skin commensal yeast Malassezia sympodialis.
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Genomic predictors of the maximal O₂ uptake response to standardized exercise training programs.
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Getting more from less: algorithms for rapid protein identification with multiple short peptide sequences.
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Global analysis of protein folding thermodynamics for disease state characterization.
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Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR).
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Global phosphotyrosinylated protein profile of cell-matrix adhesion complexes of trabecular meshwork cells.
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Growth-Phase-Specific Modulation of Cell Morphology and Gene Expression by an Archaeal Histone Protein.
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Halobacterium salinarum NRC-1 PeptideAtlas: toward strategies for targeted proteomics and improved proteome coverage.
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Haploinsufficiency for Core Exon Junction Complex Components Disrupts Embryonic Neurogenesis and Causes p53-Mediated Microcephaly.
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Heat map visualization of complex environmental and biomarker measurements.
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Highly recurrent CBS epimutations in gastric cancer CpG island methylator phenotypes and inflammation.
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Human skeletal muscle fibre contractile properties and proteomic profile: adaptations to 3 weeks of unilateral lower limb suspension and active recovery.
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Hybrid origin of SIV in chimpanzees.
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Hyperphosphorylated C-terminal repeat domain-associating proteins in the nuclear proteome link transcription to DNA/chromatin modification and RNA processing.
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Ibudilast sensitizes glioblastoma to temozolomide by targeting Macrophage Migration Inhibitory Factor (MIF).
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Identification of Protease Specificity by Combining Proteome-Derived Peptide Libraries and Quantitative Proteomics.
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Identification of an elaborate complex mediating postsynaptic inhibition.
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Identification of four proteins from the small subunit of the mammalian mitochondrial ribosome using a proteomics approach.
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Immunoinformatics approaches to explore Helicobacter Pylori proteome (Virulence Factors) to design B and T cell multi-epitope subunit vaccine.
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Improved peak detection in mass spectrum by incorporating continuous wavelet transform-based pattern matching.
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In vivo proximity proteomics of nascent synapses reveals a novel regulator of cytoskeleton-mediated synaptic maturation.
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Initial sequencing and analysis of the human genome.
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Initial sequencing and comparative analysis of the mouse genome.
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Integrative Omics: Harnessing the Proteome to Maximize the Potential of the Genome.
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Is age a key factor contributing to the disparity between success of neuroprotective strategies in young animals and limited success in elderly stroke patients? Focus on protein homeostasis.
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Joint Fluid Proteome after Anterior Cruciate Ligament Rupture Reflects an Acute Posttraumatic Inflammatory and Chondrodegenerative State.
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Kinome screen of ferroptosis reveals a novel role of ATM in regulating iron metabolism.
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Large-Scale Analysis of Breast Cancer-Related Conformational Changes in Proteins Using SILAC-SPROX.
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Layers of regulation of cell-cycle gene expression in the budding yeast Saccharomyces cerevisiae.
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Longitudinal multi-omics of host-microbe dynamics in prediabetes.
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Longitudinal study of differential protein expression in an Alzheimer's mouse model lacking inducible nitric oxide synthase.
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Mapping the proteo-genomic convergence of human diseases.
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Mass Spectrometry-Based Proteomics for Analysis of Hydrophilic Phosphopeptides.
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Metabolomics Standards Workshop and the development of international standards for reporting metabolomics experimental results.
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Metabolomics applied to diabetes research: moving from information to knowledge.
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Metaprotein expression modeling for label-free quantitative proteomics.
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Mitochondrial acetylome analysis in a mouse model of alcohol-induced liver injury utilizing SIRT3 knockout mice.
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Mixed peptide sequencing and the FASTF/FASTS algorithms.
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Molecular biologist's guide to proteomics.
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Multiscale computational analysis of Xenopus laevis morphogenesis reveals key insights of systems-level behavior.
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Multivariate proteomic analysis of murine embryonic stem cell self-renewal versus differentiation signaling.
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Mutual information in random Boolean models of regulatory networks.
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N-terminal acetylation promotes synaptonemal complex assembly in C. elegans.
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Nasopharyngeal Protein Biomarkers of Acute Respiratory Virus Infection.
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New secrets behind bone metastasis.
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Noise-limited frequency signal transmission in gene circuits.
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Novel breast cancer biomarkers identified by integrative proteomic and gene expression mapping.
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Organization of enzyme concentration across the metabolic network in cancer cells.
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Phosphoproteome Integration Reveals Patient-Specific Networks in Prostate Cancer.
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Phosphoproteome analysis in yeast.
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Phosphoproteome analysis of capacitated human sperm. Evidence of tyrosine phosphorylation of a kinase-anchoring protein 3 and valosin-containing protein/p97 during capacitation.
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Phosphoproteomic profiling of human myocardial tissues distinguishes ischemic from non-ischemic end stage heart failure.
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Phosphoproteomics for the masses.
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Physiological Genomics: Who we are and where we're going.
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Post-transcriptional operons and regulons co-ordinating gene expression.
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Profoundly lower muscle mass and rate of contractile protein synthesis in boys with Duchenne muscular dystrophy.
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Protein Folding Stability Changes Across the Proteome Reveal Targets of Cu Toxicity in E. coli
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Protein prediction for trait mapping in diverse populations.
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Proteome analyses using accurate mass and elution time peptide tags with capillary LC time-of-flight mass spectrometry.
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Proteome analysis by mass spectrometry.
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Proteome-Wide Characterization of Phosphorylation-Induced Conformational Changes in Breast Cancer.
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Proteome-Wide Structural Biology: An Emerging Field for the Structural Analysis of Proteins on the Proteomic Scale.
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Proteome-wide analysis reveals widespread lysine acetylation of major protein complexes in the malaria parasite.
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Proteome-wide muscle protein fractional synthesis rates predict muscle mass gain in response to a selective androgen receptor modulator in rats.
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Proteome-wide search reveals unexpected RNA-binding proteins in Saccharomyces cerevisiae.
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Proteomic Analysis of Primary Human Airway Epithelial Cells Exposed to the Respiratory Toxicant Diacetyl.
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Proteomic Profiling of Human Hepatic Stellate Cell Line LX2 Responses to Irradiation and TGF-β1.
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Proteomic analysis of S-nitrosylation and denitrosylation by resin-assisted capture.
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Proteomic analysis of cardiac response to thermal acclimation in the eurythermal goby fish Gillichthys mirabilis.
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Proteomic analysis of human bronchoalveolar lavage fluid after subsgemental exposure.
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Proteomic analysis of mitochondrial-associated ER membranes (MAM) during RNA virus infection reveals dynamic changes in protein and organelle trafficking.
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Proteomic analysis of mitotic RNA polymerase II reveals novel interactors and association with proteins dysfunctional in disease.
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Proteomic analysis of the NOS2 interactome in human airway epithelial cells.
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Proteomic analysis of urinary extracellular vesicles reveal biomarkers for neurologic disease.
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Proteomic and immunologic analyses of brain tumor exosomes.
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Proteomic characterization of the cellular response to nitrosative stress mediated by s-nitrosoglutathione reductase inhibition.
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Proteomic profiling of nuclei from native renal inner medullary collecting duct cells using LC-MS/MS.
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Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
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Quantifying Competition among Mitochondrial Protein Acylation Events Induced by Ethanol Metabolism.
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Quantitative H2S-mediated protein sulfhydration reveals metabolic reprogramming during the integrated stress response.
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Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.
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Quantitative analysis of the chromatin proteome in disease reveals remodeling principles and identifies high mobility group protein B2 as a regulator of hypertrophic growth.
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Quantitative proteome analysis of colorectal cancer-related differential proteins.
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Quantitative proteomics reveals metabolic and pathogenic properties of Chlamydia trachomatis developmental forms.
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Rapid identification of monospecific monoclonal antibodies using a human proteome microarray.
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Recent advances for measurement of protein synthesis rates, use of the 'Virtual Biopsy' approach, and measurement of muscle mass.
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Regulation of iron transport related genes by boron in the marine bacterium Marinobacter algicola DG893.
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Remodeling of the Acetylproteome by SIRT3 Manipulation Fails to Affect Insulin Secretion or β Cell Metabolism in the Absence of Overnutrition.
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Reprioritization of biofilm metabolism is associated with nutrient adaptation and long-term survival of Haemophilus influenzae.
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Residual dipolar couplings: synergy between NMR and structural genomics.
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Reverse engineering gene regulatory networks.
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Ribonucleoprotein infrastructure regulating the flow of genetic information between the genome and the proteome.
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Ring finger protein 121 is a potent regulator of adeno-associated viral genome transcription.
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S-nitrosothiols and the S-nitrosoproteome of the cardiovascular system.
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SILAC-pulse proteolysis: A mass spectrometry-based method for discovery and cross-validation in proteome-wide studies of ligand binding.
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SUMO proteomics to decipher the SUMO-modified proteome regulated by various diseases.
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Scanning Quadrupole Data-Independent Acquisition, Part A: Qualitative and Quantitative Characterization.
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Sequence heuristics to encode phase behaviour in intrinsically disordered protein polymers.
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Simultaneous generation of aptamers to multiple gamma-carboxyglutamic acid proteins from a focused aptamer library using DeSELEX and convergent selection.
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Small ubiquitin-like modifier 3-modified proteome regulated by brain ischemia in novel small ubiquitin-like modifier transgenic mice: putative protective proteins/pathways.
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Solid-phase capture for the detection and relative quantification of S-nitrosoproteins by mass spectrometry.
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StableIsotope Labeling with Amino Acids in Cell Culture (SILAC)-based strategy for proteome-wide thermodynamic analysis of protein-ligand binding interactions.
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Systemic surfaceome profiling identifies target antigens for immune-based therapy in subtypes of advanced prostate cancer.
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Targeted Proteomics of Human Metapneumovirus in Clinical Samples and Viral Cultures.
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Targeted proteomic profiling of renal Na(+) transporter and channel abundances in angiotensin II type 1a receptor knockout mice.
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The Diacetyl-Exposed Human Airway Epithelial Secretome: New Insights into Flavoring-Induced Airways Disease.
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The Primary Effect on the Proteome of ARID1A-mutated Ovarian Clear Cell Carcinoma is Downregulation of the Mevalonate Pathway at the Post-transcriptional Level.
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The Protein Kinase A-Dependent Phosphoproteome of the Human Pathogen Aspergillus fumigatus Reveals Diverse Virulence-Associated Kinase Targets.
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The Role of SUMOylation and Ubiquitination in Brain Ischaemia: Critical Concepts and Clinical Implications.
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The anatomy of microbial cell state transitions in response to oxygen.
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The metabolomics standards initiative.
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The protein expression landscape of the Arabidopsis root.
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The purinome, a complex mix of drug and toxicity targets.
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The somatic genomic landscape of glioblastoma.
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The urinary proteome infers dysregulation of mitochondrial, lysosomal, and protein reabsorption processes in chronic kidney disease of unknown etiology (CKDu).
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Thermodynamic analysis of protein-ligand interactions in complex biological mixtures using a shotgun proteomics approach.
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Transcriptional and proteomic insights into the host response in fatal COVID-19 cases.
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Transcriptional profiling of Alzheimer blood mononuclear cells by microarray.
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Use of artificial neural networks for the accurate prediction of peptide liquid chromatography elution times in proteome analyses.
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Vagal nerve stimulation modifies neuronal activity and the proteome of excitatory synapses of amygdala/piriform cortex.
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Visual annotation of the gene database.
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WNK1 regulates uterine homeostasis and its ability to support pregnancy.
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Whole Genome Sequence Analysis of the Plasma Proteome in Black Adults Provides Novel Insights Into Cardiovascular Disease.
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p300-Mediated Lysine 2-Hydroxyisobutyrylation Regulates Glycolysis.
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Keywords of People
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Ferguson, P. Lee,
Associate Professor of Civil and Environmental Engineering,
Civil and Environmental Engineering
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Garman, Katherine Schuver,
Associate Professor of Medicine,
Medicine, Gastroenterology
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Hartemink, Alexander J.,
Professor in the Department of Computer Science,
Biology
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Hirschey, Matthew,
Associate Professor of Medicine,
Cell Biology
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McCall, Shannon Jones,
Associate Professor of Pathology,
Pathology
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Milano, Carmelo Alessio,
Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery,
Surgery, Cardiovascular and Thoracic Surgery
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Pang, Herbert,
Adjunct Assistant Professor in the Department of Biostatistics & Bioinformatics,
Biostatistics & Bioinformatics
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Sampson, John Howard,
Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine,
Biomedical Engineering