Neutrophil Infiltration

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  Subject Areas on Research

  • 2-O, 3-O-desulfated heparin inhibits neutrophil elastase-induced HMGB-1 secretion and airway inflammation. 
  • Apolipoproteins and apolipoprotein mimetic peptides modulate phagocyte trafficking through chemotactic activity. 
  • Augmented Responses to Ozone in Obese Mice Require IL-17A and Gastrin-Releasing Peptide. 
  • Brain radiation injury leads to a dose- and time-dependent recruitment of peripheral myeloid cells that depends on CCR2 signaling. 
  • Cranial irradiation leads to acute and persistent neuroinflammation with delayed increases in T-cell infiltration and CD11c expression in C57BL/6 mouse brain. 
  • Delayed wound healing in the absence of intercellular adhesion molecule-1 or L-selectin expression. 
  • Endothelial selectins regulate skin wound healing in cooperation with L-selectin and ICAM-1. 
  • Exposure to particulate hexavalent chromium exacerbates allergic asthma pathology. 
  • Extrapulmonary Aspergillus infection in patients with CARD9 deficiency. 
  • Hydroxychloroquine attenuates renal ischemia/reperfusion injury by inhibiting cathepsin mediated NLRP3 inflammasome activation. 
  • In vivo myocardial protection from ischemia/reperfusion injury by the peroxisome proliferator-activated receptor-gamma agonist rosiglitazone. 
  • Keratocan and lumican regulate neutrophil infiltration and corneal clarity in lipopolysaccharide-induced keratitis by direct interaction with CXCL1. 
  • Lactobacillus rhamnosus GG and Bifidobacterium longum attenuate lung injury and inflammatory response in experimental sepsis. 
  • Lactobacillus rhamnosus GG improves outcome in experimental pseudomonas aeruginosa pneumonia: potential role of regulatory T cells. 
  • Lung inflammation, injury, and proliferative response after repetitive particulate hexavalent chromium exposure. 
  • NOX2 protects against prolonged inflammation, lung injury, and mortality following systemic insults. 
  • Pulmonary toxicity of instilled silver nanoparticles: influence of size, coating and rat strain. 
  • Pure MnTBAP selectively scavenges peroxynitrite over superoxide: comparison of pure and commercial MnTBAP samples to MnTE-2-PyP in two models of oxidative stress injury, an SOD-specific Escherichia coli model and carrageenan-induced pleurisy. 
  • STK11/LKB1 Deficiency Promotes Neutrophil Recruitment and Proinflammatory Cytokine Production to Suppress T-cell Activity in the Lung Tumor Microenvironment. 
  • The Phagocyte Oxidase Controls Tolerance to Mycobacterium tuberculosis Infection. 
  • The critical role of hematopoietic cells in lipopolysaccharide-induced airway inflammation. 
  • The extracellular matrix protein mindin serves as an integrin ligand and is critical for inflammatory cell recruitment. 
  • The role of the extracellular matrix protein mindin in airway response to environmental airways injury. 
  • Timing of valproic acid in acute lung injury: prevention is the best therapy? 
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  Keywords of People

  • Chen, Jun, Associate Professor of Medicine, Duke Cancer Institute
  • Gunn, Michael Dee, Professor of Medicine, Immunology