Polymorphism, Single Nucleotide

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  Subject Areas on Research

  • 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function. 
  • 172G>T variant in the 5' untranslated region of DNA repair gene RAD51 reduces risk of squamous cell carcinoma of the head and neck and interacts with a P53 codon 72 variant. 
  • 5-HTTLPR and gender moderate changes in negative affect responses to tryptophan infusion. 
  • A 137-kb deletion within the Potocki-Shaffer syndrome interval on chromosome 11p11.2 associated with developmental delay and hypotonia. 
  • A 3.9-centimorgan-resolution human single-nucleotide polymorphism linkage map and screening set. 
  • A 32 kb critical region excluding Y402H in CFH mediates risk for age-related macular degeneration. 
  • A Common Polymorphism in a Williams Syndrome Gene Predicts Amygdala Reactivity and Extraversion in Healthy Adults. 
  • A Cross-Cancer Genetic Association Analysis of the DNA Repair and DNA Damage Signaling Pathways for Lung, Ovary, Prostate, Breast, and Colorectal Cancer. 
  • A Functional Polymorphism (rs2494752) in the AKT1 Promoter Region and Gastric Adenocarcinoma Risk in an Eastern Chinese Population. 
  • A GWAS Study on Liver Function Test Using eMERGE Network Participants. 
  • A Genome-Wide Association Study Identifies Two Novel Susceptible Regions for Squamous Cell Carcinoma of the Head and Neck. 
  • A Genome-Wide Association Study of 2304 Extreme Longevity Cases Identifies Novel Longevity Variants. 
  • A Heritable Missense Polymorphism in CDKN2A Confers Strong Risk of Childhood Acute Lymphoblastic Leukemia and Is Preferentially Selected during Clonal Evolution. 
  • A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. 
  • A Missense Variant in PTPN22 is a Risk Factor for Drug-induced Liver Injury. 
  • A NEIL1 single nucleotide polymorphism (rs4462560) predicts the risk of radiation-induced toxicities in esophageal cancer patients treated with definitive radiotherapy. 
  • A Novel Genetic Variant in Long Non-coding RNA Gene NEXN-AS1 is Associated with Risk of Lung Cancer. 
  • A Novel Recurrent COL5A1 Genetic Variant Is Associated With a Dysplasia-Associated Arterial Disease Exhibiting Dissections and Fibromuscular Dysplasia. 
  • A PGC1β genetic variant associated with nevus count and melanoma mortality. 
  • A PheWAS approach in studying HLA-DRB1*1501. 
  • A TGF-β1 genetic variant at the miRNA187 binding site significantly modifies risk of HPV16-associated oropharyngeal cancer. 
  • A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease. 
  • A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk. 
  • A catalog of neutral and deleterious polymorphism in yeast. 
  • A cellular genome-wide association study reveals human variation in microtubule stability and a role in inflammatory cell death. 
  • A common biological basis of obesity and nicotine addiction. 
  • A common polymorphism in the 3'UTR of cyclooxygenase 2/prostaglandin synthase 2 gene and risk of lung cancer in a Chinese population. 
  • A common single nucleotide polymorphism A118G of the μ opioid receptor alters its N-glycosylation and protein stability. 
  • A common variant associated with prostate cancer in European and African populations. 
  • A common variant in the CDKN2B gene on chromosome 9p21 protects against coronary artery disease in Americans of African ancestry. 
  • A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome. 
  • A common variant near TGFBR3 is associated with primary open angle glaucoma. 
  • A common variant on chromosome 9p21 affects the risk of myocardial infarction. 
  • A comparison of major histocompatibility complex SNPs in Han Chinese residing in Taiwan and Caucasians. 
  • A composite single-nucleotide polymorphism prediction signature for extranodal natural killer/T-cell lymphoma. 
  • A comprehensive gene-environment interaction analysis in Ovarian Cancer using genome-wide significant common variants. 
  • A comprehensive genome-wide analysis of melanoma Breslow thickness identifies interaction between CDC42 and SCIN genetic variants. 
  • A comprehensive survey of genomic alterations in gastric cancer reveals systematic patterns of molecular exclusivity and co-occurrence among distinct therapeutic targets. 
  • A cytosine-thymine (CT)-rich haplotype in intron 4 of SNCA confers risk for Lewy body pathology in Alzheimer's disease and affects SNCA expression. 
  • A founder mutation in the Ashkenazi Jewish population affecting messenger RNA splicing of the CCM2 gene causes cerebral cavernous malformations. 
  • A functional NQO1 609C>T polymorphism and risk of gastrointestinal cancers: a meta-analysis. 
  • A functional alternative splicing mutation in human tryptophan hydroxylase-2. 
  • A functional polymorphism in the ATP-Binding Cassette B1 transporter predicts pharmacologic response to combination of nortriptyline and morphine in neuropathic pain patients. 
  • A functional polymorphism in the CEBPE gene promoter influences acute lymphoblastic leukemia risk through interaction with the hematopoietic transcription factor Ikaros. 
  • A functional polymorphism in the HTR2C gene associated with stress responses: a validation study. 
  • A functional variant (-1304T>G) in the MKK4 promoter contributes to a decreased risk of lung cancer by increasing the promoter activity. 
  • A functional variant at the miR-184 binding site in TNFAIP2 and risk of squamous cell carcinoma of the head and neck. 
  • A functional variant at the miR-885-5p binding site of CASP3 confers risk of both index and second primary malignancies in patients with head and neck cancer. 
  • A functional variant at the miRNA binding site in E2F1 gene is associated with risk and tumor HPV16 status of oropharynx squamous cell carcinoma. 
  • A functional variant in HOXA11-AS, a novel long non-coding RNA, inhibits the oncogenic phenotype of epithelial ovarian cancer. 
  • A genetic risk score based on direct associations with coronary heart disease improves coronary heart disease risk prediction in the Atherosclerosis Risk in Communities (ARIC), but not in the Rotterdam and Framingham Offspring, Studies. 
  • A genetic risk score is associated with incident cardiovascular disease and coronary artery calcium: the Framingham Heart Study. 
  • A genetic stochastic process model for genome-wide joint analysis of biomarker dynamics and disease susceptibility with longitudinal data. 
  • A genetic variant in the APE1/Ref-1 gene promoter -141T/G may modulate risk of glioblastoma in a Chinese Han population. 
  • A genetic variant near GATA3 implicated in inherited susceptibility and etiology of benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS). 
  • A genetic variant within MDM4 3'UTR miRNA binding site is associated with HPV16-positive tumors and survival of oropharyngeal cancer. 
  • A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. 
  • A genome-wide analysis of putative functional and exonic variation associated with extremely high intelligence 
  • A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. 
  • A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation. 
  • A genome-wide association scan (GWAS) for mean telomere length within the COGS project: identified loci show little association with hormone-related cancer risk. 
  • A genome-wide association study for coronary artery disease identifies a novel susceptibility locus in the major histocompatibility complex. 
  • A genome-wide association study for extremely high intelligence. 
  • A genome-wide association study for myopia and refractive error identifies a susceptibility locus at 15q25. 
  • A genome-wide association study identified a novel genetic loci STON1-GTF2A1L/LHCGR/FSHR for bilaterality of neovascular age-related macular degeneration. 
  • A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2. 
  • A genome-wide association study identifies a novel susceptibility locus for the immunogenicity of polyethylene glycol. 
  • A genome-wide association study identifies new loci for ACE activity: potential implications for response to ACE inhibitor. 
  • A genome-wide association study identifies novel loci for paclitaxel-induced sensory peripheral neuropathy in CALGB 40101. 
  • A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24. 
  • A genome-wide association study identifies susceptibility variants for type 2 diabetes in Han Chinese. 
  • A genome-wide association study implicates the APOE locus in nonpathological cognitive ageing. 
  • A genome-wide association study of central corneal thickness in Latinos. 
  • A genome-wide association study of corneal astigmatism: The CREAM Consortium. 
  • A genome-wide association study of depressive symptoms. 
  • A genome-wide association study of intra-ocular pressure suggests a novel association in the gene FAM125B in the TwinsUK cohort. 
  • A genome-wide association study of myasthenia gravis. 
  • A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303. 
  • A genome-wide association study of resistance to HIV infection in highly exposed uninfected individuals with hemophilia A. 
  • A genome-wide association study of suicide attempts in the million veterans program identifies evidence of pan-ancestry and ancestry-specific risk loci. 
  • A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia. 
  • A genome-wide association study reveals a quantitative trait locus of adiponectin on CDH13 that predicts cardiometabolic outcomes. 
  • A genome-wide association study suggests new evidence for an association of the NADPH Oxidase 4 (NOX4) gene with severe diabetic retinopathy in type 2 diabetes. 
  • A genome-wide in vitro bacterial-infection screen reveals human variation in the host response associated with inflammatory disease. 
  • A genome-wide investigation of SNPs and CNVs in schizophrenia. 
  • A genome-wide linkage and association scan reveals novel loci for autism. 
  • A genome-wide scan for common alleles affecting risk for autism. 
  • A genome-wide search for linkage to asthma phenotypes in the genetics of asthma international network families: evidence for a major susceptibility locus on chromosome 2p. 
  • A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB. 
  • A genome-wide study of preferential amplification/hybridization in microarray-based pooled DNA experiments. 
  • A genome-wide survey of copy number variations in Han Chinese residing in Taiwan. 
  • A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression. 
  • A global reference for human genetic variation. 
  • A haplotype map of the human genome. 
  • A high-density genome-wide association screen of sporadic ALS in US veterans. 
  • A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC. 
  • A hybrid bayesian approach for genome-wide association studies on related individuals. 
  • A hybrid framework for genome wide epistasis discovery. 
  • A large kindred of early-onset osteoarthritis of the knee and hip: excluding the link to COL2A1 gene. 
  • A large-scale genome-wide association study meta-analysis of cannabis use disorder. 
  • A large-scale survey of genetic copy number variations among Han Chinese residing in Taiwan. 
  • A latent model for prioritization of SNPs for functional studies. 
  • A low-frequency variant at 8q24.21 is strongly associated with risk of oligodendroglial tumors and astrocytomas with IDH1 or IDH2 mutation. 
  • A meta-analysis and genome-wide association study of platelet count and mean platelet volume in african americans. 
  • A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. 
  • A meta-analysis of gene expression signatures of blood pressure and hypertension. 
  • A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2. 
  • A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease. 
  • A missense variant in FGD6 confers increased risk of polypoidal choroidal vasculopathy. 
  • A molecular mechanism for the differential regulation of TGF-beta1 expression due to the common SNP -509C-T (c. -1347C > T). 
  • A multi-population phenome-wide association study of genetically-predicted height in the Million Veteran Program. 
  • A new analysis tool for individual-level allele frequency for genomic studies. 
  • A new method to accurately identify single nucleotide variants using small FFPE breast samples. 
  • A novel Alzheimer disease locus located near the gene encoding tau protein. 
  • A novel TCF7L2 type 2 diabetes SNP identified from fine mapping in African American women. 
  • A novel XPF -357A>C polymorphism predicts risk and recurrence of bladder cancer. 
  • A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorder. 
  • A novel functional DEC1 promoter polymorphism -249T>C reduces risk of squamous cell carcinoma of the head and neck. 
  • A novel functional VKORC1 promoter polymorphism is associated with inter-individual and inter-ethnic differences in warfarin sensitivity. 
  • A novel functional polymorphism C1797G in the MDM2 promoter is associated with risk of bladder cancer in a Chinese population. 
  • A novel functional variant (-842G>C) in the PIN1 promoter contributes to decreased risk of squamous cell carcinoma of the head and neck by diminishing the promoter activity. 
  • A novel genetic locus modulates infarct volume independently of the extent of collateral circulation. 
  • A novel haplotype-sharing approach for genome-wide case-control association studies implicates the calpastatin gene in Parkinson's disease. 
  • A pharmacogenetic investigation of intravenous furosemide in decompensated heart failure: a meta-analysis of three clinical trials. 
  • A pharmacogenetic study of aldehyde oxidase I in patients treated with XK469. 
  • A pilot genome-wide association study shows genomic variants enriched in the non-tumor cells of patients with well-differentiated neuroendocrine tumors of the ileum. 
  • A pleiotropic ATM variant (rs1800057 C>G) is associated with risk of multiple cancers. 
  • A polymorphism in the HCP5 gene associated with HLA-B*5701 does not restrict HIV-1 in vitro. 
  • A polymorphism in the VKORC1 regulator calumenin predicts higher warfarin dose requirements in African Americans. 
  • A polymorphism in the base excision repair gene PARP2 is associated with differential prognosis by chemotherapy among postmenopausal breast cancer patients. 
  • A polymorphism within the promoter of the TGFβ1 gene is associated with radiation sensitivity using an objective radiologic endpoint. 
  • A preliminary exploration of college smokers' reactions to nicotine dependence genetic susceptibility feedback. 
  • A pri-miR-218 variant and risk of cervical carcinoma in Chinese women. 
  • A putative causal relationship between genetically determined female body shape and posttraumatic stress disorder. 
  • A putatively functional polymorphism in the HTR2C gene is associated with depressive symptoms in white females reporting significant life stress. 
  • A real-time PCR assay to identify and discriminate among wild-type and vaccine strains of varicella-zoster virus and herpes simplex virus in clinical specimens, and comparison with the clinical diagnoses. 
  • A recurrent 16p12.1 microdeletion supports a two-hit model for severe developmental delay. 
  • A regression-based association test for case-control studies that uses inferred ancestral haplotype similarity. 
  • A remark about CYP1A1 Thr461Asn genotype frequencies in a recent endometrial cancer case-control study. 
  • A role for the CD38 rs3796863 polymorphism in alcohol and monetary reward: evidence from CD38 knockout mice and alcohol self-administration, [11C]-raclopride binding, and functional MRI in humans. 
  • A role of matrix metalloproteinase-8 in atherosclerosis. 
  • A saturated map of common genetic variants associated with human height. 
  • A second generation human haplotype map of over 3.1 million SNPs. 
  • A second major histocompatibility complex susceptibility locus for multiple sclerosis. 
  • A simple and improved correction for population stratification in case-control studies. 
  • A simple procedure for the analysis of single nucleotide polymorphisms facilitates map-based cloning in Arabidopsis. 
  • A single nucleotide polymorphism in the alcohol dehydrogenase 7 gene (alanine to glycine substitution at amino acid 92) is associated with the risk of squamous cell carcinoma of the head and neck. 
  • A splicing variant of TERT identified by GWAS interacts with menopausal estrogen therapy in risk of ovarian cancer. 
  • A spontaneous deletion within the desmoglein 3 extracellular domain of mice results in hypomorphic protein expression, immunodeficiency, and a wasting disease phenotype. 
  • A statistical framework for cross-tissue transcriptome-wide association analysis. 
  • A statistical method for region-based meta-analysis of genome-wide association studies in genetically diverse populations. 
  • A study assessing the association of glycated hemoglobin A1C (HbA1C) associated variants with HbA1C, chronic kidney disease and diabetic retinopathy in populations of Asian ancestry. 
  • A study in scarlet: MC1R as the main predictor of red hair and exemplar of the flip-flop effect. 
  • A study of the TNF/LTA/LTB locus and susceptibility to severe malaria in highland papuan children and adults. 
  • A substrate specific functional polymorphism of human gamma-glutamyl hydrolase alters catalytic activity and methotrexate polyglutamate accumulation in acute lymphoblastic leukaemia cells. 
  • A targeted genetic association study of epithelial ovarian cancer susceptibility. 
  • A two-stage genome-wide association study of sporadic amyotrophic lateral sclerosis. 
  • A variant at a potentially functional microRNA-binding site in BRIP1 was associated with risk of squamous cell carcinoma of the head and neck. 
  • A variant in FTO shows association with melanoma risk not due to BMI. 
  • A variant in the CHEK2 promoter at a methylation site relieves transcriptional repression and confers reduced risk of lung cancer. 
  • A variant of the LRP4 gene affects the risk of chronic lymphocytic leukaemia transformation to Richter syndrome. 
  • A whole genome approach for discovering the genetic basis of blood group antigens: independent confirmation for P1 and Xg^a . 
  • A whole-genome association study of major determinants for host control of HIV-1. 
  • ABCA transporter gene expression and poor outcome in epithelial ovarian cancer. 
  • ABCB1 (MDR1) polymorphisms and ovarian cancer progression and survival: a comprehensive analysis from the Ovarian Cancer Association Consortium and The Cancer Genome Atlas. 
  • ABCC5, a gene that influences the anterior chamber depth, is associated with primary angle closure glaucoma. 
  • ABO blood group and risk of epithelial ovarian cancer within the Ovarian Cancer Association Consortium. 
  • AGTR1 gene variation: association with depression and frontotemporal morphology. 
  • AKT1 polymorphisms are associated with risk for metabolic syndrome. 
  • ALOX5AP variants are associated with in-stent restenosis after percutaneous coronary intervention. 
  • APOE region molecular signatures of Alzheimer's disease across races/ethnicities. 
  • APOL1 risk alleles among individuals with CKD in Northern Tanzania: A pilot study. 
  • APOL1 variants increase risk for FSGS and HIVAN but not IgA nephropathy. 
  • AQP1 and SLC4A10 as candidate genes for primary open-angle glaucoma. 
  • ARID5B genetic polymorphisms contribute to racial disparities in the incidence and treatment outcome of childhood acute lymphoblastic leukemia. 
  • ATM polymorphisms predict severe radiation pneumonitis in patients with non-small cell lung cancer treated with definitive radiation therapy. 
  • Aberrant allele frequencies of the SNPs located in microRNA target sites are potentially associated with human cancers. 
  • Absence of truncating BRIP1 mutations in chromosome 17q-linked hereditary prostate cancer families. 
  • Abundant copy-number loss of CYCLOPS and STOP genes in gastric adenocarcinoma. 
  • Accounting for linkage in family-based tests of association with missing parental genotypes. 
  • Accuracy of Inferred APOE Genotypes for a Range of Genotyping Arrays and Imputation Reference Panels. 
  • Adenylate cyclase 7 is implicated in the biology of depression and modulation of affective neural circuitry. 
  • Adult body mass index and risk of ovarian cancer by subtype: a Mendelian randomization study. 
  • Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis. 
  • Advances in pharmacogenomic research and development. 
  • African-derived genetic polymorphisms in TNFAIP3 mediate risk for autoimmunity. 
  • Age-Dependent Effects of Catechol-O-Methyltransferase (COMT) Gene Val158Met Polymorphism on Language Function in Developing Children. 
  • Age-related susceptibility to severe malaria associated with galectin-2 in highland Papuans. 
  • Age-specific genome-wide association study in glioblastoma identifies increased proportion of 'lower grade glioma'-like features associated with younger age. 
  • Aggregate Effects of Intraocular Pressure and Cup-to-Disc Ratio Genetic Variants on Glaucoma in a Multiethnic Asian Population. 
  • Aging-related atherosclerosis is exacerbated by arterial expression of tumor necrosis factor receptor-1: evidence from mouse models and human association studies. 
  • Agonist-dependence of functional properties for common nonsynonymous variants of human transient receptor potential vanilloid 1. 
  • Aldose Reductase Polymorphisms, Fasting Blood Glucose, and Age-Related Cortical Cataract. 
  • Allele-specific analysis reveals exon- and cell-type-specific regulatory effects of Alzheimer's disease-associated genetic variants. 
  • Allele-specific gene expression in a wild nonhuman primate population. 
  • Alleles associated with physical activity levels are estimated to be older than anatomically modern humans. 
  • Allelic association of sequence variants in the herpes virus entry mediator-B gene (PVRL2) with the severity of multiple sclerosis. 
  • Allelic differences in the brain-derived neurotrophic factor Val66Met polymorphism in late-life depression. 
  • Allelic diversity in the TGFB1 regulatory region: characterization of novel functional single nucleotide polymorphisms. 
  • Alzheimer disease pathology in cognitively healthy elderly: a genome-wide study. 
  • Alzheimer's Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci. 
  • Amygdala functional connectivity, HPA axis genetic variation, and life stress in children and relations to anxiety and emotion regulation. 
  • Amyotrophic lateral sclerosis: an emerging era of collaborative gene discovery. 
  • An "almost exhaustive" search-based sequential permutation method for detecting epistasis in disease association studies. 
  • An ERCC4 regulatory variant predicts grade-3 or -4 toxicities in patients with advanced non-small cell lung cancer treated by platinum-based therapy. 
  • An FTO variant is associated with Type 2 diabetes in South Asian populations after accounting for body mass index and waist circumference. 
  • An analysis of single nucleotide polymorphisms of 125 DNA repair genes in the Texas genome-wide association study of lung cancer with a replication for the XRCC4 SNPs. 
  • An analysis paradigm for investigating multi-locus effects in complex disease: examination of three GABA receptor subunit genes on 15q11-q13 as risk factors for autistic disorder. 
  • An application of Random Forests to a genome-wide association dataset: methodological considerations & new findings. 
  • An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility. 
  • An eQTL Landscape of Kidney Tissue in Human Nephrotic Syndrome. 
  • An epigenetic pathway in rice connects genetic variation to anaerobic germination and seedling establishment. 
  • An evaluation of copy number variation detection tools from whole-exome sequencing data. 
  • An initial genetic analysis of gemcitabine-induced high-grade neutropenia in pancreatic cancer patients in CALGB 80303 (Alliance). 
  • An integrated encyclopedia of DNA elements in the human genome. 
  • An integrated genome and phenome-wide association study approach to understanding Alzheimer's disease predisposition. 
  • An integrated genomic analysis of human glioblastoma multiforme. 
  • An integrated map of genetic variation from 1,092 human genomes. 
  • An intergenic risk locus containing an enhancer deletion in 2q35 modulates breast cancer risk by deregulating IGFBP5 expression. 
  • An international collaborative family-based whole genome quantitative trait linkage scan for myopic refractive error. 
  • An international collaborative family-based whole-genome linkage scan for high-grade myopia. 
  • An intronic poly (AT) polymorphism of the DNA repair gene XPC and risk of squamous cell carcinoma of the head and neck: a case-control study. 
  • An miR-502-binding site single-nucleotide polymorphism in the 3'-untranslated region of the SET8 gene is associated with early age of breast cancer onset. 
  • An oxytocin receptor polymorphism predicts amygdala reactivity and antisocial behavior in men. 
  • Analyses on mutation patterns, detection of population bottlenecks, and suggestion of deleterious-compensatory evolution among members of the genus Potyvirus. 
  • Analysis combining correlated glaucoma traits identifies five new risk loci for open-angle glaucoma. 
  • Analysis of 60 reported glioma risk SNPs replicates published GWAS findings but fails to replicate associations from published candidate-gene studies. 
  • Analysis of DNA methylation in a three-generation family reveals widespread genetic influence on epigenetic regulation. 
  • Analysis of European mitochondrial haplogroups with Alzheimer disease risk. 
  • Analysis of LOXL1 polymorphisms in a United States population with pseudoexfoliation glaucoma. 
  • Analysis of association at single nucleotide polymorphisms in the APOE region. 
  • Analysis of non-synonymous-coding variants of Parkinson's disease-related pathogenic and susceptibility genes in East Asian populations. 
  • Analysis of over 10,000 Cases finds no association between previously reported candidate polymorphisms and ovarian cancer outcome. 
  • Analysis of single nucleotide polymorphisms and radiation sensitivity of the lung assessed with an objective radiologic endpoin. 
  • Analysis of single nucleotide polymorphisms in the NOS2A gene and interaction with smoking in age-related macular degeneration. 
  • Analysis of the RELN gene as a genetic risk factor for autism. 
  • Analysis of the autism chromosome 2 linkage region: GAD1 and other candidate genes. 
  • Ancestry and pharmacogenomics of relapse in acute lymphoblastic leukemia. 
  • Angiogenic, neurotrophic, and inflammatory system SNPs moderate the association between birth weight and ADHD symptom severity. 
  • Angiotensin-converting enzyme gene polymorphism predicts the time-course of blood pressure response to angiotensin converting enzyme inhibition in the AASK trial. 
  • Anthracycline-related cardiomyopathy after childhood cancer: role of polymorphisms in carbonyl reductase genes--a report from the Children's Oncology Group. 
  • Antibody Fc effector functions and IgG3 associate with decreased HIV-1 risk. 
  • Antiepileptic Drug Teratogenicity and De Novo Genetic Variation Load. 
  • Apolipoprotein E region molecular signatures of Alzheimer's disease. 
  • Apoptotic variants as predictors of risk of oropharyngeal cancer recurrence after definitive radiotherapy. 
  • Architecture of the human regulatory network derived from ENCODE data. 
  • Are C-reactive protein associated genetic variants associated with serum levels and retinal markers of microvascular pathology in Asian populations from Singapore? 
  • Arteriovenous malformation. 
  • Aspirin resistance and a single gene. 
  • Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data. 
  • Assessing the genetic architecture of epithelial ovarian cancer histological subtypes. 
  • Assessing the utility of whole genome amplified DNA for next-generation molecular ecology. 
  • Assessment of Multifactor Gene-Environment Interactions and Ovarian Cancer Risk: Candidate Genes, Obesity, and Hormone-Related Risk Factors. 
  • Assessment of gene-by-sex interaction effect on bone mineral density. 
  • Assessment of genetic and nongenetic interactions for the prediction of depressive symptomatology: an analysis of the Wisconsin Longitudinal Study using machine learning algorithms. 
  • Assessment of hepatocyte growth factor in ovarian cancer mortality. 
  • Assessment of moderate coffee consumption and risk of epithelial ovarian cancer: a Mendelian randomization study. 
  • Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers. 
  • Assessment of the genetic variance of late-onset Alzheimer's disease. 
  • Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with risk of clear cell ovarian cancer. 
  • Association Between Polygenic Risk Score and the Progression from Mild Cognitive Impairment to Alzheimer's Disease. 
  • Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study. 
  • Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels. 
  • Association analysis of 9,560 prostate cancer cases from the International Consortium of Prostate Cancer Genetics confirms the role of reported prostate cancer associated SNPs for familial disease. 
  • Association analysis of chromosome 15 gabaa receptor subunit genes in autistic disorder. 
  • Association and interactions between DNA repair gene polymorphisms and adult glioma. 
  • Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data. 
  • Association between CASP8 and CASP10 polymorphisms and toxicity outcomes with platinum-based chemotherapy in Chinese patients with non-small cell lung cancer. 
  • Association between DNA damage response and repair genes and risk of invasive serous ovarian cancer. 
  • Association between KRAS rs61764370 and triple-negative breast cancer--a false positive? 
  • Association between XPF polymorphisms and cancer risk: a meta-analysis. 
  • Association between a functional polymorphism (-1195T>C) in the IGFBP5 promoter and head and neck cancer risk. 
  • Association between a rare novel TP53 variant (rs78378222) and melanoma, squamous cell carcinoma of head and neck and lung cancer susceptibility in non-Hispanic Whites. 
  • Association between chromosome 2p16.3 variants and glaucoma in populations of African descent. 
  • Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies. 
  • Association between common germline genetic variation in 94 candidate genes or regions and risks of invasive epithelial ovarian cancer. 
  • Association between delta-aminolevulinic acid dehydratase (ALAD) polymorphism and blood lead levels: a meta-regression analysis. 
  • Association between functional polymorphisms in genes involved in the MAPK signaling pathways and cutaneous melanoma risk. 
  • Association between germline variants and somatic mutations in colorectal cancer. 
  • Association between germline variation in the FHIT gene and prostate cancer in Caucasians and African Americans. 
  • Association between invasive ovarian cancer susceptibility and 11 best candidate SNPs from breast cancer genome-wide association study. 
  • Association between miRNA-binding site polymorphisms in double-strand break repair genes and risk of recurrence in patients with squamous cell carcinomas of the non-oropharynx. 
  • Association between novel PLCE1 variants identified in published esophageal cancer genome-wide association studies and risk of squamous cell carcinoma of the head and neck. 
  • Association between polymorphisms in the GSTA4 gene and risk of lung cancer: a case-control study in a Southeastern Chinese population. 
  • Association between putative functional variants in the PSMB9 gene and risk of melanoma--re-analysis of published melanoma genome-wide association studies. 
  • Association between single nucleotide polymorphisms in ERCC4 and risk of squamous cell carcinoma of the head and neck. 
  • Association between single nucleotide polymorphisms of the transforming growth factor β1 gene and the risk of severe radiation esophagitis in patients with lung cancer. 
  • Association between the ERCC5 Asp1104His polymorphism and cancer risk: a meta-analysis. 
  • Association between the FTO rs9939609 single nucleotide polymorphism and dietary adherence during a 2-year caloric restriction intervention: Exploratory analyses from CALERIE™ phase 2. 
  • Association between the chromosome 9p21 locus and angiographic coronary artery disease burden: a collaborative meta-analysis. 
  • Association between the neuron-specific RNA-binding protein ELAVL4 and Parkinson disease. 
  • Association between treatment-emergent suicidal ideation with citalopram and polymorphisms near cyclic adenosine monophosphate response element binding protein in the STAR*D study. 
  • Association between two functional polymorphisms of insulin-like growth factor binding protein 3 and colorectal cancer risk in a Chinese population. 
  • Association mapping of the high-grade myopia MYP3 locus reveals novel candidates UHRF1BP1L, PTPRR, and PPFIA2. 
  • Association of AGTR1 with 18-month treatment outcome in late-life depression. 
  • Association of BRCA1 functional single nucleotide polymorphisms with risk of differentiated thyroid carcinoma. 
  • Association of CARD8 Activating Polymorphism With Bone Erosion in Cholesteatoma Patients. 
  • Association of CASP7 polymorphisms and survival of patients with non-small cell lung cancer with platinum-based chemotherapy treatment. 
  • Association of CAV1/CAV2 genomic variants with primary open-angle glaucoma overall and by gender and pattern of visual field loss. 
  • Association of CYP2B6 Single-Nucleotide Polymorphisms Altering Efavirenz Metabolism With Hepatitis C Virus (HCV) Treatment Relapse Among Human Immunodeficiency Virus/HCV-Coinfected African Americans Receiving Ledipasvir/Sofosbuvir in the ION-4 Trial. 
  • Association of CYP2C19 polymorphisms and lansoprazole-associated respiratory adverse effects in children. 
  • Association of Common Genetic Polymorphisms with Melanoma Patient IL-12p40 Blood Levels, Risk, and Outcomes. 
  • Association of Economic Status and Educational Attainment With Posttraumatic Stress Disorder: A Mendelian Randomization Study. 
  • Association of Epidemiologic Factors and Genetic Variants Influencing Hypothalamic-Pituitary-Adrenocortical Axis Function With Postconcussive Symptoms After Minor Motor Vehicle Collision. 
  • Association of Forced Vital Capacity with the Developmental Gene NCOR2. 
  • Association of GATA3 Polymorphisms With Minimal Residual Disease and Relapse Risk in Childhood Acute Lymphoblastic Leukemia. 
  • Association of Genetic Variants With Primary Open-Angle Glaucoma Among Individuals With African Ancestry. 
  • Association of IL6ST (gp130) Polymorphism with Functional Outcome Following Spontaneous Intracerebral Hemorrhage. 
  • Association of Interleukin 6 Receptor Variant With Cardiovascular Disease Effects of Interleukin 6 Receptor Blocking Therapy: A Phenome-Wide Association Study. 
  • Association of LEP G2548A and LEPR Q223R polymorphisms with cancer susceptibility: evidence from a meta-analysis. 
  • Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study. 
  • Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals. 
  • Association of SLC11A1 with tuberculosis and interactions with NOS2A and TLR2 in African-Americans and Caucasians. 
  • Association of TGF-beta1 genetic variants with HPV16-positive oropharyngeal cancer. 
  • Association of XRCC1 polymorphisms and risk of differentiated thyroid carcinoma: a case-control analysis. 
  • Association of a cystatin C gene variant with cystatin C levels, CKD, and risk of incident cardiovascular disease and mortality. 
  • Association of a novel functional promoter variant (rs2075533 C>T) in the apoptosis gene TNFSF8 with risk of lung cancer--a finding from Texas lung cancer genome-wide association study. 
  • Association of a single nucleotide polymorphism near the interleukin-28B gene with response to hepatitis C therapy in HIV/hepatitis C virus-coinfected patients. 
  • Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans. 
  • Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy. 
  • Association of estrogen receptor β polymorphisms with posterior tibial tendon dysfunction. 
  • Association of exome sequences with plasma C-reactive protein levels in >9000 participants. 
  • Association of gene variants of the renin-angiotensin system with accelerated hippocampal volume loss and cognitive decline in old age. 
  • Association of genetic variants of FBXO32 and FOXO6 in the FOXO pathway with breast cancer risk. 
  • Association of genetic variants of O6-methylguanine-DNA methyltransferase with risk of lung cancer in non-Hispanic Whites. 
  • Association of genetic variants on 8p21 and 4q12 with age-related macular degeneration in Asian populations. 
  • Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians. 
  • Association of genetic variation in IKZF1, ARID5B, and CEBPE and surrogates for early-life infections with the risk of acute lymphoblastic leukemia in Hispanic children. 
  • Association of granulomatosis with polyangiitis (Wegener's) with HLA-DPB1*04 and SEMA6A gene variants: evidence from genome-wide analysis. 
  • Association of heart rate and diabetes among 0.5 million adults in the China Kadoorie biobank: Results from observational and Mendelian randomization analyses. 
  • Association of human aryl hydrocarbon receptor gene polymorphisms with risk of lung cancer among cigarette smokers in a Chinese population. 
  • Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. 
  • Association of matrix metalloproteinase-8 gene variation with breast cancer prognosis. 
  • Association of multi-drug resistance gene polymorphisms with pancreatic cancer outcome. 
  • Association of polygenic risk score with the risk of chronic lymphocytic leukemia and monoclonal B-cell lymphocytosis. 
  • Association of polymorphisms in genes regulating the corticotropin-releasing factor system with antidepressant treatment response. 
  • Association of polymorphisms in one-carbon metabolizing genes and lung cancer risk: a case-control study in Chinese population. 
  • Association of polymorphisms in the apolipoprotein E region with susceptibility to and progression of multiple sclerosis. 
  • Association of sequence variants on chromosomes 20, 11, and 5 (20q13.33, 11q23.3, and 5p15.33) with glioma susceptibility in a Chinese population. 
  • Association of single nucleotide polymorphisms in glycosylation genes with risk of epithelial ovarian cancer. 
  • Association of single nucleotide polymorphisms on chromosome 9p21.3 with platelet reactivity: a potential mechanism for increased vascular disease. 
  • Association of single-nucleotide polymorphisms of the tau gene with late-onset Parkinson disease. 
  • Association of the IL2RA/CD25 gene with juvenile idiopathic arthritis. 
  • Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. 
  • Association of tumor necrosis factor-alpha promoter variants with risk of HPV-associated oral squamous cell carcinoma. 
  • Association of two CASP8 polymorphisms with breast cancer risk: a meta-analysis. 
  • Association of variants in FRAP1 and PDGFRA with corneal curvature in Asian populations from Singapore. 
  • Association of vitamin D levels and risk of ovarian cancer: a Mendelian randomization study. 
  • Association study of Parkin gene polymorphisms with idiopathic Parkinson disease. 
  • Association study of genetic polymorphisms of SLC2A10 gene and type 2 diabetes in the Taiwanese population. 
  • Association study of nicotinic acetylcholine receptor genes identifies a novel lung cancer susceptibility locus near CHRNA1 in African-Americans. 
  • Association study of two interleukin-1 gene loci with essential hypertension in a Pakistani Pathan population. 
  • Association test for X-linked QTL in family-based designs. 
  • Association test using Copy Number Profile Curves (CONCUR) enhances power in rare copy number variant analysis. 
  • Associations Between Catecholaminergic and Serotonergic Genes and Persistent Arm Pain Severity Following Breast Cancer Surgery. 
  • Associations Between Catecholaminergic and Serotonergic Genes and Persistent Breast Pain Phenotypes After Breast Cancer Surgery. 
  • Associations between APOE variants and metabolic traits and the impact of psychological stress. 
  • Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study. 
  • Associations between RNA splicing regulatory variants of stemness-related genes and racial disparities in susceptibility to prostate cancer. 
  • Associations between genetic variants in mRNA splicing-related genes and risk of lung cancer: a pathway-based analysis from published GWASs. 
  • Associations between genetic variants of KIF5B, FMN1, and MGAT3 in the cadherin pathway and pancreatic cancer risk. 
  • Associations between serotonin transporter gene promoter region (5-HTTLPR) polymorphism and gaze bias for emotional information. 
  • Associations between smoking behavior-related alleles and the risk of melanoma. 
  • Associations between variants near a monoaminergic pathways gene (PHOX2B) and amygdala reactivity: a genome-wide functional imaging study. 
  • Associations of ABCB1 3435C>T and IL-10-1082G>A polymorphisms with long-term sirolimus dose requirements in renal transplant patients. 
  • Associations of ABCB1 and IL-10 genetic polymorphisms with sirolimus-induced dyslipidemia in renal transplant recipients. 
  • Associations of Lys939Gln and Ala499Val polymorphisms of the XPC gene with cancer susceptibility: a meta-analysis. 
  • Associations of PI3KR1 and mTOR polymorphisms with esophageal squamous cell carcinoma risk and gene-environment interactions in Eastern Chinese populations. 
  • Associations of candidate genes to age-related macular degeneration among racial/ethnic groups in the multi-ethnic study of atherosclerosis. 
  • Associations of genotypes and haplotypes of IL-17 with risk of gastric cancer in an eastern Chinese population. 
  • Associations of high-grade glioma with glioma risk alleles and histories of allergy and smoking. 
  • Associations of potentially functional variants in IL-6, JAKs and STAT3 with gastric cancer risk in an eastern Chinese population. 
  • Associations of prostate cancer risk variants with disease aggressiveness: results of the NCI-SPORE Genetics Working Group analysis of 18,343 cases. 
  • Atenolol induced HDL-C change in the pharmacogenomic evaluation of antihypertensive responses (PEAR) study. 
  • Atrial Fibrillation and Ischemic Stroke With the Amyloidogenic V122I Transthyretin Variant Among Black Americans. 
  • Attempted replication of 50 reported asthma risk genes identifies a SNP in RAD50 as associated with childhood atopic asthma. 
  • Autism genome-wide copy number variation reveals ubiquitin and neuronal genes. 
  • Automatic diagnosis of pathological myopia from heterogeneous biomedical data. 
  • Axon guidance pathways served as common targets for human speech/language evolution and related disorders. 
  • BDNF Val66Met and spontaneous dyskinesias in non-clinical psychosis. 
  • BDNF Val66Met genotype and 6-month remission rates in late-life depression. 
  • BMI1 enhancer polymorphism underlies chromosome 10p12.31 association with childhood acute lymphoblastic leukemia. 
  • BRAF polymorphisms and the risk of ovarian cancer of low malignant potential. 
  • BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers. 
  • Behavioral epigenetics and the developmental origins of child mental health disorders. 
  • Beneficial IL28B genotype associated with lower frequency of hepatic steatosis in patients with chronic hepatitis C. 
  • Best practices and joint calling of the HumanExome BeadChip: the CHARGE Consortium. 
  • Beta-2 adrenergic receptor gene (ADRB2) polymorphism and risk for lung adenocarcinoma: a case-control study in a Chinese population. 
  • Beta-defensin 1, aryl hydrocarbon receptor and plasma kynurenine in major depressive disorder: metabolomics-informed genomics. 
  • Beta2-adrenergic receptor genotype affects the renin-angiotensin-aldosterone system response to the Dietary Approaches to Stop Hypertension (DASH) dietary pattern. 
  • Bevacizumab-induced hypertension and proteinuria: a genome-wide study of more than 1000 patients. 
  • Bioinformatics strategy to advance the interpretation of Alzheimer's disease GWAS discoveries: The roads from association to causation. 
  • Biological annotation of genetic loci associated with intelligence in a meta-analysis of 87,740 individuals. 
  • Biological, clinical and population relevance of 95 loci for blood lipids. 
  • Biology of cerebral arteriovenous malformations with a focus on inflammation. 
  • Biomarkers of NAFLD progression: a lipidomics approach to an epidemic. 
  • Biopsychosocial Influence on Shoulder Pain: Influence of Genetic and Psychological Combinations on Twelve-Month Postoperative Pain and Disability Outcomes. 
  • Bipolar disorder, brain-derived neurotrophic factor (BDNF) Val66Met polymorphism and brain morphology. 
  • Birth Cohort, Age, and Sex Strongly Modulate Effects of Lipid Risk Alleles Identified in Genome-Wide Association Studies. 
  • Bitter Taste Receptors and Chronic Otitis Media. 
  • Blood pressure-associated polymorphism controls ARHGAP42 expression via serum response factor DNA binding. 
  • Body mass index and obesity- and diabetes-associated genotypes and risk for pancreatic cancer. 
  • Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism interacts with gender to influence cortisol responses to mental stress. 
  • Brain-derived neurotrophic factor val66met polymorphism and hippocampal activation during episodic encoding and retrieval tasks. 
  • Breast cancer risk factors differ between Asian and white women with BRCA1/2 mutations. 
  • Brief Report: The Genetic Profile of Rheumatoid Factor-Positive Polyarticular Juvenile Idiopathic Arthritis Resembles That of Adult Rheumatoid Arthritis. 
  • Bromodomain protein 4 discriminates tissue-specific super-enhancers containing disease-specific susceptibility loci in prostate and breast cancer. 
  • C3 R102G polymorphism increases risk of age-related macular degeneration. 
  • CASP7 variants modify susceptibility to cervical cancer in Chinese women. 
  • CD45-deficient severe combined immunodeficiency caused by uniparental disomy. 
  • CDKN2B-AS1 genotype-glaucoma feature correlations in primary open-angle glaucoma patients from the United States. 
  • CELF4 Variant and Anthracycline-Related Cardiomyopathy: A Children's Oncology Group Genome-Wide Association Study. 
  • CFH and VIPR2 as susceptibility loci in choroidal thickness and pachychoroid disease central serous chorioretinopathy. 
  • CHRM2, parental monitoring, and adolescent externalizing behavior: evidence for gene-environment interaction. 
  • CMPK1 and RBP3 are associated with corneal curvature in Asian populations. 
  • COL1A1 and COL2A1 genes and myopia susceptibility: evidence of association and suggestive linkage to the COL2A1 locus. 
  • COMT Val(158) Met genotype is associated with reward learning: a replication study and meta-analysis. 
  • COMT Val158Met Polymorphism, Cardiometabolic Risk, and Nadir CD4 Synergistically Increase Risk of Neurocognitive Impairment in Men Living With HIV. 
  • COMT and anxiety and cognition in children with chromosome 22q11.2 deletion syndrome. 
  • COMT gene locus: new functional variants. 
  • CPAG: software for leveraging pleiotropy in GWAS to reveal similarity between human traits links plasma fatty acids and intestinal inflammation. 
  • CREBBP and STAT6 co-mutation and 16p13 and 1p36 loss define the t(14;18)-negative diffuse variant of follicular lymphoma. 
  • CRHBP polymorphisms predict chronic pain development following motor vehicle collision. 
  • CX3CR1-dependent renal macrophage survival promotes Candida control and host survival. 
  • CXCR1-mediated neutrophil degranulation and fungal killing promote Candida clearance and host survival. 
  • CYP1A1 genetic polymorphism is a promising predictor to improve chemotherapy effects in patients with metastatic breast cancer treated with docetaxel plus thiotepa vs. docetaxel plus capecitabine. 
  • CYP1B1, MYOC, and LTBP2 mutations in primary congenital glaucoma patients in the United States. 
  • CYP2C19 and PON1 polymorphisms regulating clopidogrel bioactivation in Chinese, Malay and Indian subjects. 
  • CYP2C19 variation and citalopram response. 
  • CYP2C9*1B promoter polymorphisms, in linkage with CYP2C19*2, affect phenytoin autoinduction of clearance and maintenance dose. 
  • CYP3A4/5 and pharmacogenetics in patients with sarcoma - Authors' reply. 
  • Can Genetics Predict Response to Complex Behavioral Interventions? Evidence from a Genetic Analysis of the Fast Track Randomized Control Trial 
  • Can polymorphisms predict response to antiarrhythmic drugs in atrial fibrillation? 
  • Candidate gene analysis using imputed genotypes: cell cycle single-nucleotide polymorphisms and ovarian cancer risk. 
  • Candidate gene association study for diabetic retinopathy in persons with type 2 diabetes: the Candidate gene Association Resource (CARe). 
  • Candidate gene variants of the immune system and sudden infant death syndrome. 
  • Candidate genes on murine chromosome 8 are associated with susceptibility to Staphylococcus aureus infection in mice and are involved with Staphylococcus aureus septicemia in humans. 
  • Case-Only Survival Analysis Reveals Unique Effects of Genotype, Sex, and Coronary Disease Severity on Survivorship. 
  • Causal Effect of Plasminogen Activator Inhibitor Type 1 on Coronary Heart Disease. 
  • Causal effects of cardiovascular risk factors on onset of major age-related diseases: A time-to-event Mendelian randomization study. 
  • Cell cycle genes and ovarian cancer susceptibility: a tagSNP analysis. 
  • Cell-type-specific enrichment of risk-associated regulatory elements at ovarian cancer susceptibility loci. 
  • Challenges in the phenotypic characterisation of patients in genetic studies of coronary artery disease. 
  • Changes of plasma vWF level in response to the improvement of air quality: an observation of 114 healthy young adults. 
  • Characterization of T gene sequence variants and germline duplications in familial and sporadic chordoma. 
  • Characterization of a Human-Specific Tandem Repeat Associated with Bipolar Disorder and Schizophrenia. 
  • Characterization of serum proteins associated with IL28B genotype among patients with chronic hepatitis C. 
  • Childhood gene-environment interactions and age-dependent effects of genetic variants associated with refractive error and myopia: The CREAM Consortium. 
  • Cholinergic augmentation of insulin release requires ankyrin-B. 
  • Chromosomal and genetic alterations in human hepatocellular adenomas associated with type Ia glycogen storage disease. 
  • Chromosome 17q12 variants contribute to risk of early-onset prostate cancer. 
  • Chromosome 4q25 variants and biomarkers of myocardial fibrosis in patients with atrial fibrillation. 
  • Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices. 
  • Chromosomes 4 and 8 implicated in a genome wide SNP linkage scan of 762 prostate cancer families collected by the ICPCG. 
  • Chronic family stress moderates the association between a TOMM40 variant and triglyceride levels in two independent Caucasian samples. 
  • Chronic lymphocytic leukemia in African Americans. 
  • Cigarette smoking strongly modifies the association of LOC387715 and age-related macular degeneration. 
  • Circulating vitamin D concentration and risk of seven cancers: Mendelian randomisation study. 
  • Circulating vitamin D concentrations and risk of breast and prostate cancer: a Mendelian randomization study. 
  • Cis-acting polymorphisms affect complex traits through modifications of microRNA regulation pathways. 
  • Cis-regulatory evolution of chalcone-synthase expression in the genus Arabidopsis. 
  • Clarifying the role of ATOH7 in glaucoma endophenotypes. 
  • Cleavage and polyadenylation specificity factor 1 (CPSF1) regulates alternative splicing of interleukin 7 receptor (IL7R) exon 6. 
  • Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for IFNL3 (IL28B) genotype and PEG interferon-α-based regimens. 
  • Clinical and Genetic Risk Factors for Acute Pancreatitis in Patients With Acute Lymphoblastic Leukemia. 
  • Clinical and Genetic Risk Prediction of Subsequent CNS Tumors in Survivors of Childhood Cancer: A Report From the COG ALTE03N1 Study. 
  • Clinical and biological relevance of genomic heterogeneity in chronic lymphocytic leukemia. 
  • Clinical outcome and gene- and microRNA-expression profiling according to the Wilms tumor 1 (WT1) single nucleotide polymorphism rs16754 in adult de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study. 
  • Clopidogrel response variability and the advent of personalised antiplatelet therapy. A bench to bedside journey. 
  • Collaborative Ocular Oncology Group report number 1: prospective validation of a multi-gene prognostic assay in uveal melanoma. 
  • Collagen-related genes influence the glaucoma risk factor, central corneal thickness. 
  • Combined effects of E2F1 and E2F2 polymorphisms on risk and early onset of squamous cell carcinoma of the head and neck. 
  • Combined genotype and haplotype tests for region-based association studies. 
  • Combined p53-related genetic variants together with HPV infection increase oral cancer risk. 
  • Comment on 'A PAX6 gene polymorphism is associated with genetic predisposition to extreme myopia'. 
  • Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD. 
  • Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk. 
  • Common Genetic Variation and Susceptibility to Ovarian Cancer: Current Insights and Future Directions. 
  • Common Polymorphisms of CYP2B6 Influence Stereoselective Bupropion Disposition. 
  • Common alleles in candidate susceptibility genes associated with risk and development of epithelial ovarian cancer. 
  • Common genetic determinants of breast-cancer risk in East Asian women: a collaborative study of 23 637 breast cancer cases and 25 579 controls. 
  • Common genetic determinants of intraocular pressure and primary open-angle glaucoma. 
  • Common genetic determinants of vitamin D insufficiency: a genome-wide association study. 
  • Common genetic polymorphisms contribute to the association between chronic lymphocytic leukaemia and non-melanoma skin cancer. 
  • Common genetic variants associated with resting oxygenation in chronic obstructive pulmonary disease. 
  • Common genetic variants associated with telomere length confer risk for neuroblastoma and other childhood cancers. 
  • Common genetic variants near the Brittle Cornea Syndrome locus ZNF469 influence the blinding disease risk factor central corneal thickness. 
  • Common genetic variants of the β2-adrenergic receptor affect its translational efficiency and are associated with human longevity. 
  • Common genetic variants on 5p14.1 associate with autism spectrum disorders. 
  • Common genetic variants on 8q24 contribute to susceptibility to bladder cancer in a Chinese population. 
  • Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies. 
  • Common genetic variation and performance on standardized cognitive tests. 
  • Common genetic variation and risk of osteosarcoma in a multi-ethnic pediatric and adolescent population. 
  • Common genetic variation and susceptibility to partial epilepsies: a genome-wide association study. 
  • Common genetic variation and the control of HIV-1 in humans. 
  • Common genetic variation in the indoleamine-2,3-dioxygenase genes and antidepressant treatment outcome in major depressive disorder. 
  • Common genetic variation near the connexin-43 gene is associated with resting heart rate in African Americans: a genome-wide association study of 13,372 participants. 
  • Common mechanisms underlying refractive error identified in functional analysis of gene lists from genome-wide association study results in 2 European British cohorts. 
  • Common minor histocompatibility antigen discovery based upon patient clinical outcomes and genomic data. 
  • Common non-synonymous polymorphisms in the BRCA1 Associated RING Domain (BARD1) gene are associated with breast cancer susceptibility: a case-control analysis. 
  • Common variants associated with plasma triglycerides and risk for coronary artery disease. 
  • Common variants at 19p13 are associated with susceptibility to ovarian cancer. 
  • Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. 
  • Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma. 
  • Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. 
  • Common variants at the CHEK2 gene locus and risk of epithelial ovarian cancer. 
  • Common variants in Mendelian kidney disease genes and their association with renal function. 
  • Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels. 
  • Common variants in the periostin gene influence development of atherosclerosis in young persons. 
  • Common variants near ABCA1 and in PMM2 are associated with primary open-angle glaucoma. 
  • Common variants near ABCA1, AFAP1 and GMDS confer risk of primary open-angle glaucoma. 
  • Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma. 
  • Common variants within 6p21.31 locus are associated with chronic lymphocytic leukaemia and, potentially, other non-Hodgkin lymphoma subtypes. 
  • Common variation in Nemo-like kinase is associated with risk of ovarian cancer. 
  • Common variation in the BRCA1 gene and prostate cancer risk. 
  • Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas. 
  • Comparative analyses of seven algorithms for copy number variant identification from single nucleotide polymorphism arrays. 
  • Comparative phenotypic and CARD15 mutational analysis among African American, Hispanic, and White children with Crohn's disease. 
  • Comparing Effects of FOXO3 and Residing in Urban Areas on Longevity: A Gene-Environment Interaction Study. 
  • Comparing Mammography Abnormality Features to Genetic Variants in the Prediction of Breast Cancer in Women Recommended for Breast Biopsy. 
  • Comparing methods for performing trans-ethnic meta-analysis of genome-wide association studies. 
  • Comparing the value of mammographic features and genetic variants in breast cancer risk prediction. 
  • Comparison of Corneal Biomechanical Properties between Indian and Chinese Adults. 
  • Complement Factor H Inhibits CD47-Mediated Resolution of Inflammation. 
  • Complement factor H in AMD: Bridging genetic associations and pathobiology. 
  • Complement factor H increases risk for atrophic age-related macular degeneration. 
  • Complement factor H variant increases the risk of age-related macular degeneration. 
  • Complete Sequence of the 22q11.2 Allele in 1,053 Subjects with 22q11.2 Deletion Syndrome Reveals Modifiers of Conotruncal Heart Defects. 
  • Complex multilocus effects of catechol-O-methyltransferase haplotypes predict pain and pain interference 6 weeks after motor vehicle collision. 
  • Complex phenotypes and phenomenon of genome-wide inter-chromosomal linkage disequilibrium in the human genome. 
  • Complex relationship between Parkin mutations and Parkinson disease. 
  • Complex-trait analysis in plants. 
  • Component-wise gradient boosting and false discovery control in survival analysis with high-dimensional covariates. 
  • Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients. 
  • Comprehensive analysis of LAMC1 genetic variants in advanced pelvic organ prolapse. 
  • Comprehensive genetic analysis of the human lipidome identifies loci associated with lipid homeostasis with links to coronary artery disease. 
  • Comprehensive genetic analysis of the platelet activating factor acetylhydrolase (PLA2G7) gene and cardiovascular disease in case-control and family datasets. 
  • Computing a Synthetic Chronic Psychosocial Stress Measurement in Multiple Datasets and its Application in the Replication of G × E Interactions of the EBF1 Gene. 
  • Concordance of genetic variation that increases risk for anxiety disorders and posttraumatic stress disorders and that influences their underlying neurocircuitry. 
  • Consortium analysis of 7 candidate SNPs for ovarian cancer. 
  • Consortium analysis of gene and gene-folate interactions in purine and pyrimidine metabolism pathways with ovarian carcinoma risk. 
  • Consumption of meat is associated with higher fasting glucose and insulin concentrations regardless of glucose and insulin genetic risk scores: a meta-analysis of 50,345 Caucasians. 
  • Contemporary Considerations for Constructing a Genetic Risk Score: An Empirical Approach. 
  • Convergent adaptation of human lactase persistence in Africa and Europe. 
  • Convergent effects of mouse Pet-1 deletion and human PET-1 variation on amygdala fear and threat processing. 
  • Convergent patterns of association between phenylalanine hydroxylase variants and schizophrenia in four independent samples. 
  • Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity 
  • Copy Number Variants Are Ovarian Cancer Risk Alleles at Known and Novel Risk Loci. 
  • Coronary artery disease and the thrombospondin single nucleotide polymorphisms. 
  • Correlation between base-excision repair gene polymorphisms and levels of in-vitro BPDE-induced DNA adducts in cultured peripheral blood lymphocytes. 
  • Correlation of Color Fundus Photograph Grading with Risks of Early Age-related Macular Degeneration by using Automated OCT-derived Drusen Measurements. 
  • Corroboration of a familial chordoma locus on chromosome 7q and evidence of genetic heterogeneity using single nucleotide polymorphisms (SNPs). 
  • Cortisol responses to emotional stress in men: association with a functional polymorphism in the 5HTR2C gene. 
  • CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease. 
  • Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases. 
  • Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer. 
  • Cross-disorder genomewide analysis of schizophrenia, bipolar disorder, and depression. 
  • Current state of our knowledge on brain tumor epidemiology. 
  • Cyclin D1 G870A polymorphism and breast cancer risk: a meta-analysis comprising 9,911 cases and 11,171 controls. 
  • Cytochrome P450 1A1 (CYP1A1) gene polymorphisms and cervical cancer risk: a meta-analysis. 
  • Cytokine gene polymorphisms and the outcome of invasive candidiasis: a prospective cohort study. 
  • Cytokine gene polymorphisms are not associated with bronchiolitis obliterans syndrome or survival after lung transplant. 
  • DIACYLGLYCEROL ACYLTRANSFERASE1 Contributes to Freezing Tolerance. 
  • DNA mismatch repair gene polymorphisms affect survival in pancreatic cancer. 
  • DNA mismatch repair network gene polymorphism as a susceptibility factor for pancreatic cancer. 
  • DNA repair gene polymorphisms and risk of pancreatic cancer. 
  • DNAH5 is associated with total lung capacity in chronic obstructive pulmonary disease. 
  • DNase I sensitivity QTLs are a major determinant of human expression variation. 
  • De novo MECP2 duplication derived from paternal germ line result in dysmorphism and developmental delay. 
  • Deceased donor multidrug resistance protein 1 and caveolin 1 gene variants may influence allograft survival in kidney transplantation. 
  • Deceased-Donor Apolipoprotein L1 Renal-Risk Variants Have Minimal Effects on Liver Transplant Outcomes. 
  • Decreased E-cadherin expression correlates with higher stage of Wilms' tumors. 
  • Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries. 
  • Deep whole-genome sequencing of 100 southeast Asian Malays. 
  • Defining the contribution of CNTNAP2 to autism susceptibility. 
  • Defining the role of common variation in the genomic and biological architecture of adult human height. 
  • Definition of a functional single nucleotide polymorphism in the cell migration inhibitory gene MIIP that affects the risk of breast cancer. 
  • Deletion of CFHR3 and CFHR1 genes in age-related macular degeneration. 
  • Dense genotyping of immune-related loci in idiopathic inflammatory myopathies confirms HLA alleles as the strongest genetic risk factor and suggests different genetic background for major clinical subgroups. 
  • Design and Implementation of the International Genetics and Translational Research in Transplantation Network. 
  • Detecting differential copy number variation between groups of samples. 
  • Detection and reporting of homozygosity associated with consanguinity in the clinical laboratory. 
  • Detection of genetic loci associated with plasma fetuin-A: a meta-analysis of genome-wide association studies from the CHARGE Consortium. 
  • Determination of human platelet antigen typing by molecular methods: Importance in diagnosis and early treatment of neonatal alloimmune thrombocytopenia. 
  • Development and evaluation of a genetic risk score for obesity. 
  • Differential effects of MDM2 SNP309 polymorphism on breast cancer risk along with race: a meta-analysis. 
  • Differential susceptibility to adolescent externalizing trajectories: examining the interplay between CHRM2 and peer group antisocial behavior. 
  • Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry. 
  • Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis. 
  • Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure. 
  • Disentangling the genetics of lean mass. 
  • Disruptive mRNA folding increases translational efficiency of catechol-O-methyltransferase variant. 
  • Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors. 
  • Dissecting the regulatory architecture of gene expression QTLs. 
  • Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking. 
  • Distinct single amino acid replacements in the control of virulence regulator protein differentially impact streptococcal pathogenesis. 
  • Distribution of WDR36 DNA sequence variants in patients with primary open-angle glaucoma. 
  • Distribution of optineurin sequence variations in an ethnically diverse population of low-tension glaucoma patients from the United States. 
  • Diversity of variant alleles encoding Kidd, Duffy, and Kell antigens in individuals with sickle cell disease using whole genome sequencing data from the NHLBI TOPMed Program. 
  • Does race modify the association between CYP1B1 Val432Leu polymorphism and breast cancer risk? A critical appraisal of a recent meta-analysis. 
  • Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium. 
  • Drug-gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT interval. 
  • Duffy (Fy), DARC, and neutropenia among women from the United States, Europe and the Caribbean. 
  • Dysregulation of DGCR6 and DGCR6L: psychopathological outcomes in chromosome 22q11.2 deletion syndrome. 
  • Dysregulation of innate immunity in hepatitis C virus genotype 1 IL28B-unfavorable genotype patients: impaired viral kinetics and therapeutic response. 
  • E2F transcription factor 2 variants as predictive biomarkers for recurrence risk in patients with squamous cell carcinoma of the oropharynx. 
  • ERCC1 and ERCC2 variants predict survival in gastric cancer patients. 
  • ERRgamma regulates cardiac, gastric, and renal potassium homeostasis. 
  • ERα PvuII and XbaI polymorphisms in postmenopausal women with posterior tibial tendon dysfunction: a case control study. 
  • ESR1/SYNE1 polymorphism and invasive epithelial ovarian cancer risk: an Ovarian Cancer Association Consortium study. 
  • Early complement genes are associated with visual system degeneration in multiple sclerosis. 
  • Early event-related potentials to emotional faces differ for adults with autism spectrum disorder and by serotonin transporter genotype. 
  • Early onset prostate cancer has a significant genetic component. 
  • Editor's Highlight: Base Excision Repair Variants and Pesticide Exposure Increase Parkinson's Disease Risk. 
  • Education influences the association between genetic variants and refractive error: a meta-analysis of five Singapore studies. 
  • Efavirenz Metabolism: Influence of Polymorphic CYP2B6 Variants and Stereochemistry. 
  • Effect of APOE and CD33 on Cognitive Decline. 
  • Effect of CYP2C19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: a genetic substudy of the PLATO trial. 
  • Effect of FOXO3 and Air Pollution on Cognitive Function: A Longitudinal Cohort Study of Older Adults in China From 2000 to 2014. 
  • Effect of bucindolol on heart failure outcomes and heart rate response in patients with reduced ejection fraction heart failure and atrial fibrillation. 
  • Effect of catechol-O-methyltransferase polymorphism on response to propranolol therapy in chronic musculoskeletal pain: a randomized, double-blind, placebo-controlled, crossover pilot study. 
  • Effect of genetic variation in the nicotinic receptor genes on risk for posttraumatic stress disorder. 
  • Effect of genetic variations on ticagrelor plasma levels and clinical outcomes. 
  • Effect of insulin-like growth factor gene polymorphisms alone or in interaction with diabetes on the risk of pancreatic cancer. 
  • Effect of polymorphisms in XPD on clinical outcomes of platinum-based chemotherapy for Chinese non-small cell lung cancer patients. 
  • Effects of 5HTTLPR on cardiovascular response to an emotional stressor. 
  • Effects of MDM2 promoter polymorphisms and p53 codon 72 polymorphism on risk and age at onset of squamous cell carcinoma of the head and neck. 
  • Effects of base excision repair gene polymorphisms on pancreatic cancer survival. 
  • Effects of genetic variation in protease activated receptor 4 after an acute coronary syndrome: Analysis from the TRACER trial. 
  • Effects of inversions on within- and between-species recombination and divergence. 
  • Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. 
  • Effects of sequence variation on differential allelic transcription factor occupancy and gene expression. 
  • Efficacy of clopidogrel for stroke depends on CYP2C19 genotype and risk profile. 
  • Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms. 
  • Eleven genomic loci affect plasma levels of chronic inflammation marker soluble urokinase-type plasminogen activator receptor. 
  • Eligible and not eligible studies in the recent meta-analysis about p53 polymorphism and breast cancer risk. 
  • Enhancer-derived long non-coding RNAs CCAT1 and CCAT2 at rs6983267 has limited predictability for early stage colorectal carcinoma metastasis. 
  • Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information. 
  • Enhancing linkage analysis of complex disorders: an evaluation of high-density genotyping. 
  • Enrichment of putative PAX8 target genes at serous epithelial ovarian cancer susceptibility loci. 
  • Enteric microbiome metabolites correlate with response to simvastatin treatment. 
  • Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer. 
  • Epigenetic profiling identifies novel genes for ascending aortic aneurysm formation with bicuspid aortic valves. 
  • Epigenome-wide association analysis of daytime sleepiness in the Multi-Ethnic Study of Atherosclerosis reveals African-American-specific associations. 
  • Epiregulin and EGFR interactions are involved in pain processing. 
  • Epistasis amongst PTPN2 and genes of the vitamin D pathway contributes to risk of juvenile idiopathic arthritis. 
  • Epistasis between polymorphisms in COMT, ESR1, and GCH1 influences COMT enzyme activity and pain. 
  • Epistatic Gene-Based Interaction Analyses for Glaucoma in eMERGE and NEIGHBOR Consortium. 
  • Epithelial-Mesenchymal Transition (EMT) Gene Variants and Epithelial Ovarian Cancer (EOC) Risk. 
  • Equilibrative nucleoside transporter 1 gene polymorphisms and clinical outcomes following acute coronary syndromes: findings from the PLATelet inhibition and patient Outcomes (PLATO) study. 
  • Establishment of a high-efficiency SNP-based framework marker set for Arabidopsis. 
  • Estimating FST and kinship for arbitrary population structures. 
  • Estimation of the warfarin dose with clinical and pharmacogenetic data. 
  • Estrogen pathway polymorphisms in relation to primary open angle glaucoma: an analysis accounting for gender from the United States. 
  • Ethnic variation in early age-related macular degeneration lesions between white Australians and Singaporean Asians. 
  • European American stratification in ovarian cancer case control data: the utility of genome-wide data for inferring ancestry. 
  • Evaluating Associations between Average Pain Intensity and Genetic Variation in People with Sickle Cell Disease: An Exploratory Study. 
  • Evaluating DNA methylation age on the Illumina MethylationEPIC Bead Chip. 
  • Evaluating genetic susceptibility to Staphylococcus aureus bacteremia in African Americans using admixture mapping. 
  • Evaluating the ovarian cancer gonadotropin hypothesis: a candidate gene study. 
  • Evaluating the precision of EBF1 SNP x stress interaction association: sex, race, and age differences in a big harmonized data set of 28,026 participants. 
  • Evaluation of HLA polymorphisms in relation to schizophrenia risk and infectious exposure. 
  • Evaluation of Lipin 2 as a candidate gene for autosomal dominant 1 high-grade myopia. 
  • Evaluation of Primary Angle-Closure Glaucoma Susceptibility Loci in Patients with Early Stages of Angle-Closure Disease. 
  • Evaluation of candidate genes for cholinesterase activity in farmworkers exposed to organophosphorus pesticides: association of single nucleotide polymorphisms in BCHE. 
  • Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot". 
  • Evaluation of chromatin accessibility in prefrontal cortex of individuals with schizophrenia. 
  • Evaluation of the Genetic Variance of Alzheimer's Disease Explained by the Disease-Associated Chromosomal Regions. 
  • Evaluation of vitamin D biosynthesis and pathway target genes reveals UGT2A1/2 and EGFR polymorphisms associated with epithelial ovarian cancer in African American Women. 
  • Evidence for CRHR1 in multiple sclerosis using supervised machine learning and meta-analysis in 12,566 individuals. 
  • Evidence for an association between prostate cancer and chromosome 8q24 and 10q11 genetic variants in African American men: the Flint Men's Health Study. 
  • Evidence for association of SNPs in ABCB1 and CBR3, but not RAC2, NCF4, SLC28A3 or TOP2B, with chronic cardiotoxicity in a cohort of breast cancer patients treated with anthracyclines. 
  • Evidence for brain glial activation in chronic pain patients. 
  • Evidence of CNIH3 involvement in opioid dependence. 
  • Evidence of a genetic link between endometriosis and ovarian cancer. 
  • Evidence that Gsta4 modifies susceptibility to skin tumor development in mice and humans. 
  • Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation. 
  • Evolution of a malaria resistance gene in wild primates. 
  • Evolutionary adaptation of the amino acid and codon usage of the mosquito sodium channel following insecticide selection in the field mosquitoes. 
  • Examination of seven candidate regions for multiple sclerosis: strong evidence of linkage to chromosome 1q44. 
  • Exclusion of homozygous PLCE1 (NPHS3) mutations in 69 families with idiopathic and hereditary FSGS. 
  • Exome genotyping arrays to identify rare and low frequency variants associated with epithelial ovarian cancer risk. 
  • Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes. 
  • Exome-wide Sequencing Shows Low Mutation Rates and Identifies Novel Mutated Genes in Seminomas. 
  • Exome-wide age-of-onset analysis reveals exonic variants in ERN1 and SPPL2C associated with Alzheimer's disease. 
  • Exonuclease 1 (EXO1) gene variation and melanoma risk. 
  • Expansion of the human mu-opioid receptor gene architecture: novel functional variants. 
  • Explicating heterogeneity of complex traits has strong potential for improving GWAS efficiency. 
  • Exploration of a hypothesized independent association of a common 9p21.3 gene variant and ischemic stroke in patients with and without angiographic coronary artery disease. 
  • Exploratory analysis of Fas gene polymorphisms in pediatric osteosarcoma patients. 
  • Exploring the association of glyceraldehyde-3-phosphate dehydrogenase gene and Alzheimer disease. 
  • Exploring the genetic basis of chronic periodontitis: a genome-wide association study. 
  • Expression of A20 by dendritic cells preserves immune homeostasis and prevents colitis and spondyloarthritis. 
  • Extended haplotype-phasing of long-read de novo genome assemblies using Hi-C. 
  • Extracellular superoxide dismutase haplotypes are associated with acute lung injury and mortality. 
  • FAS and FASLG genetic variants and risk for second primary malignancy in patients with squamous cell carcinoma of the head and neck. 
  • FASTSNP: an always up-to-date and extendable service for SNP function analysis and prioritization. 
  • FCGR2C polymorphisms associate with HIV-1 vaccine protection in RV144 trial. 
  • FKBP5 and emotional neglect interact to predict individual differences in amygdala reactivity. 
  • FOXP2 variation in great ape populations offers insight into the evolution of communication skills. 
  • FTO affects food cravings and interacts with age to influence age-related decline in food cravings. 
  • FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals. 
  • FTO variants are associated with obesity in the Chinese and Malay populations in Singapore. 
  • Facial pain with localized and widespread manifestations: separate pathways of vulnerability. 
  • Failure to replicate effect of Kibra on human memory in two large cohorts of European origin. 
  • Family history and TOMM40 '523 interactive associations with memory in middle-aged and Alzheimer's disease cohorts. 
  • Family-Based Genome-Wide Association Study of South Indian Pedigrees Supports WNT7B as a Central Corneal Thickness Locus. 
  • Fas single nucleotide polymorphisms and risk of thyroid and salivary gland carcinomas: a case-control analysis. 
  • Fast Algorithms for Conducting Large-Scale GWAS of Age-at-Onset Traits Using Cox Mixed-Effects Models. 
  • Fast and robust association tests for untyped SNPs in case-control studies. 
  • Fc Gamma Receptor Polymorphisms Modulated the Vaccine Effect on HIV-1 Risk in the HVTN 505 HIV Vaccine Trial. 
  • Feasibility of a bilateral 4000-6000 Hz notch as a phenotype for genetic association analysis. 
  • Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster. 
  • Fiber tract-specific white matter lesion severity Findings in late-life depression and by AGTR1 A1166C genotype. 
  • Fibroblast growth factor 20 polymorphisms and haplotypes strongly influence risk of Parkinson disease. 
  • Fine mapping genetic associations between the HLA region and extremely high intelligence. 
  • Fine mapping of a linkage peak with integration of lipid traits identifies novel coronary artery disease genes on chromosome 5. 
  • Fine mapping of genetic variants in BIN1, CLU, CR1 and PICALM for association with cerebrospinal fluid biomarkers for Alzheimer's disease. 
  • Fine structure mapping of CIAS1: identification of an ancestral haplotype and a common FCAS mutation, L353P. 
  • Fine-mapping of the 5p15.33, 6p22.1-p21.31, and 15q25.1 regions identifies functional and histology-specific lung cancer susceptibility loci in African-Americans. 
  • Fine-mapping the MHC locus in juvenile idiopathic arthritis (JIA) reveals genetic heterogeneity corresponding to distinct adult inflammatory arthritic diseases. 
  • Fine-mapping, novel loci identification, and SNP association transferability in a genome-wide association study of QRS duration in African Americans. 
  • Flexible use of high-density oligonucleotide arrays for single-nucleotide polymorphism discovery and validation. 
  • Folate metabolism genes, dietary folate and response to antidepressant medications in late-life depression. 
  • Follow-up examination of linkage and association to chromosome 1q43 in multiple sclerosis. 
  • Forward and Reverse Genetic Analysis of Chlamydia. 
  • Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo. 
  • Four polymorphisms in cytochrome P450 1A1 (CYP1A1) gene and breast cancer risk: a meta-analysis. 
  • From Prescription to Transcription: Genome Sequence as Drug Target. 
  • Full-length nucleotide sequence of ERMAP alleles encoding Scianna (SC) antigens. 
  • Functional Analysis and Fine Mapping of the 9p22.2 Ovarian Cancer Susceptibility Locus. 
  • Functional Annotation Signatures of Disease Susceptibility Loci Improve SNP Association Analysis 
  • Functional FLT1 Genetic Variation is a Prognostic Factor for Recurrence in Stage I-III Non-Small-Cell Lung Cancer. 
  • Functional analysis of novel SNPs and mutations in human and mouse genomes. 
  • Functional and prognostic relevance of the -173 polymorphism of the macrophage migration inhibitory factor gene in systemic-onset juvenile idiopathic arthritis. 
  • Functional association of the parkin gene promoter with idiopathic Parkinson's disease. 
  • Functional candidate genes in age-related macular degeneration: significant association with VEGF, VLDLR, and LRP6. 
  • Functional characterization of a promoter polymorphism in APE1/Ref-1 that contributes to reduced lung cancer susceptibility. 
  • Functional genetic screen of human diversity reveals that a methionine salvage enzyme regulates inflammatory cell death. 
  • Functional genetic variants of RUVBL1 predict overall survival of Chinese patients with epithelial ovarian cancer. 
  • Functional genetic variants of XRCC4 and ERCC1 predict survival of gastric cancer patients treated with chemotherapy by regulating the gene expression. 
  • Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans. 
  • Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus. 
  • Functional organization of the genome may shape the species boundary in the house mouse. 
  • Functional polymorphism in ABCA1 influences age of symptom onset in coronary artery disease patients. 
  • Functional polymorphisms in the insulin-like binding protein-3 gene may modulate susceptibility to differentiated thyroid carcinoma in Caucasian Americans. 
  • Functional polymorphisms of CHRNA3 predict risks of chronic obstructive pulmonary disease and lung cancer in Chinese. 
  • Functional polymorphisms of JWA gene are associated with risk of bladder cancer. 
  • Functional polymorphisms of base excision repair genes XRCC1 and APEX1 predict risk of radiation pneumonitis in patients with non-small cell lung cancer treated with definitive radiation therapy. 
  • Functional polymorphisms of matrix metalloproteinase-9 are associated with risk of occurrence and metastasis of lung cancer. 
  • Functional promoter rs2868371 variant of HSPB1 associates with radiation-induced esophageal toxicity in patients with non-small-cell lung cancer treated with radio(chemo)therapy. 
  • Functional promoter variant rs2868371 of HSPB1 is associated with risk of radiation pneumonitis after chemoradiation for non-small cell lung cancer. 
  • Functional repeats (TGYCC)n in the p53-inducible gene 3 (PIG3) promoter and susceptibility to squamous cell carcinoma of the head and neck. 
  • Functional single nucleotide polymorphisms of the RASSF3 gene and susceptibility to squamous cell carcinoma of the head and neck. 
  • Functional single-nucleotide polymorphisms in the BRCA1 gene and risk of salivary gland carcinoma. 
  • Functional variant of MTOR rs2536 and survival of Chinese gastric cancer patients. 
  • Functional variants in DCAF4 associated with lung cancer risk in European populations. 
  • Functional variants in TNFAIP8 associated with cervical cancer susceptibility and clinical outcomes. 
  • Functional variants in the low-density lipoprotein receptor gene are associated with clear cell renal cell carcinoma susceptibility. 
  • Functional variations in the ATM gene and susceptibility to differentiated thyroid carcinoma. 
  • Fungal heavy metal adaptation through single nucleotide polymorphisms and copy-number variation. 
  • Further evidence for a role of the ADRB2 gene in risk for posttraumatic stress disorder. 
  • Further examination of BAFF SNPs in cGVHD. 
  • G protein-coupled receptor kinase 5 gene polymorphisms are associated with postoperative atrial fibrillation after coronary artery bypass grafting in patients receiving β-blockers. 
  • G-protein-coupled receptor kinase 4 polymorphisms and blood pressure response to metoprolol among African Americans: sex-specificity and interactions. 
  • GATA2 is associated with familial early-onset coronary artery disease. 
  • GATA3 risk alleles are associated with ancestral components in Hispanic children with ALL. 
  • GLIOGENE an International Consortium to Understand Familial Glioma. 
  • GOG 8020/210: Risk stratification of lymph node metastasis, disease progression and survival using single nucleotide polymorphisms in endometrial cancer: An NRG oncology/gynecologic oncology group study. 
  • GSNO reductase and beta2-adrenergic receptor gene-gene interaction: bronchodilator responsiveness to albuterol. 
  • GSTM1 polymorphism, GSTT1 polymorphism, and cervical cancer risk: a meta-analysis. 
  • GSTT1 and GSTP1 polymorphisms and breast cancer risk: a meta-analysis. 
  • GWAS Identifies New Loci for Painful Temporomandibular Disorder: Hispanic Community Health Study/Study of Latinos. 
  • GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium. 
  • GWAS analyzer: integrating genotype, phenotype and public annotation data for genome-wide association study analysis. 
  • GWAS in childhood acute lymphoblastic leukemia reveals novel genetic associations at chromosomes 17q12 and 8q24.21. 
  • GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer. 
  • GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium. 
  • GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal influence of schizophrenia. 
  • GWAS or Gee Whiz, PSAS or Pshaw: elucidating the biologic and clinical significance of genetic variation in cardiovascular disease. 
  • Gain-of-function lipoprotein lipase variant rs13702 modulates lipid traits through disruption of a microRNA-410 seed site. 
  • Gamma-radiation sensitivity and polymorphisms in RAD51L1 modulate glioma risk. 
  • Gemcitabine metabolic and transporter gene polymorphisms are associated with drug toxicity and efficacy in patients with locally advanced pancreatic cancer. 
  • Gene by Environment Investigation of Incident Lung Cancer Risk in African-Americans. 
  • Gene by stress genome-wide interaction analysis and path analysis identify EBF1 as a cardiovascular and metabolic risk gene. 
  • Gene expression analysis of cardiovascular diseases: novel insights into biology and clinical applications. 
  • Gene flow, divergent selection and resistance to introgression in two species of morning glories (Ipomoea). 
  • Gene signatures of postoperative atrial fibrillation in atrial tissue after coronary artery bypass grafting surgery in patients receiving β-blockers. 
  • Gene variants in angiogenesis and lymphangiogenesis and cutaneous melanoma progression. 
  • Gene × dietary pattern interactions in obesity: analysis of up to 68 317 adults of European ancestry. 
  • Gene-centric meta-analysis of lipid traits in African, East Asian and Hispanic populations. 
  • Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci. 
  • Gene-gene Interaction Analyses for Atrial Fibrillation. 
  • Gene-ontology enrichment analysis in two independent family-based samples highlights biologically plausible processes for autism spectrum disorders. 
  • General olfactory sensitivity database (GOSdb): candidate genes and their genomic variations. 
  • Genetic Colorectal Cancer and Adenoma Risk Variants Are Associated with Increasing Cumulative Adenoma Counts. 
  • Genetic Determinants of Circulating Estrogen Levels and Evidence of a Causal Effect of Estradiol on Bone Density in Men. 
  • Genetic Determinants of Circulating Lipoproteins in Nonalcoholic Fatty Liver Disease. 
  • Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders. 
  • Genetic Identification of Two Novel Loci Associated with Steroid-Sensitive Nephrotic Syndrome. 
  • Genetic Investigation Into the Differential Risk of Atrial Fibrillation Among Black and White Individuals. 
  • Genetic Polymorphisms of CFH and ARMS2 Do Not Predict Response to Antioxidants and Zinc in Patients with Age-Related Macular Degeneration: Independent Statistical Evaluations of Data from the Age-Related Eye Disease Study. 
  • Genetic Predisposition to Symptomatic Lumbar Disk Herniation in Pediatric and Young Adult Patients. 
  • Genetic Risk for Overall Cancer and the Benefit of Adherence to a Healthy Lifestyle. 
  • Genetic Sharing with Cardiovascular Disease Risk Factors and Diabetes Reveals Novel Bone Mineral Density Loci. 
  • Genetic Variants Associated With Vincristine-Induced Peripheral Neuropathy in Two Populations of Children With Acute Lymphoblastic Leukemia. 
  • Genetic Variants Associated with Circulating Fibroblast Growth Factor 23. 
  • Genetic Variants Associated with Circulating Parathyroid Hormone. 
  • Genetic Variants in CPA6 and PRPF31 Are Associated With Variation in Response to Metformin in Individuals With Type 2 Diabetes. 
  • Genetic Variants in Cyclooxygenase-2 Contribute to Post-treatment Pain among Endodontic Patients. 
  • Genetic Variants in WNT2B and BTRC Predict Melanoma Survival. 
  • Genetic Variants in the Bone Morphogenic Protein Gene Family Modify the Association between Residential Exposure to Traffic and Peripheral Arterial Disease. 
  • Genetic Variants of the MDM2 Gene Are Predictive of Treatment-Related Toxicities and Overall Survival in Patients With Advanced NSCLC. 
  • Genetic Variation Associated with Longer Telomere Length Increases Risk of Chronic Lymphocytic Leukemia. 
  • Genetic analysis in European ancestry individuals identifies 517 loci associated with liver enzymes. 
  • Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. 
  • Genetic analysis of α-synuclein 3' untranslated region and its corresponding microRNAs in relation to Parkinson's disease compared to dementia with Lewy bodies. 
  • Genetic and clinical predictors of sexual dysfunction in citalopram-treated depressed patients. 
  • Genetic and environmental factors are associated with serum 25-hydroxyvitamin D concentrations in older African Americans. 
  • Genetic and epigenetic inactivation of Kruppel-like factor 4 in medulloblastoma. 
  • Genetic and functional association of FAM5C with myocardial infarction. 
  • Genetic and non-genetic factors associated with the phenotype of exceptional longevity & normal cognition. 
  • Genetic and nongenetic covariates of pain severity in patients with adenocarcinoma of the pancreas: assessing the influence of cytokine genes. 
  • Genetic association analyses of nitric oxide synthase genes and neural tube defects vary by phenotype. 
  • Genetic association between endothelial nitric oxide synthase and Alzheimer disease. 
  • Genetic association for renal traits among participants of African ancestry reveals new loci for renal function. 
  • Genetic association of FOXO1A and FOXO3A with longevity trait in Han Chinese populations. 
  • Genetic association of insulin-like growth factor-1 polymorphisms with high-grade myopia in an international family cohort. 
  • Genetic association of refractive error and axial length with 15q14 but not 15q25 in the Blue Mountains Eye Study cohort. 
  • Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization. 
  • Genetic association study of adiposity and melanocortin-4 receptor (MC4R) common variants: replication and functional characterization of non-coding regions. 
  • Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels. 
  • Genetic associations of type 2 diabetes with islet amyloid polypeptide processing and degrading pathways in asian populations. 
  • Genetic associations with valvular calcification and aortic stenosis. 
  • Genetic contribution to variation in DNA methylation at maternal smoking-sensitive loci in exposed neonates. 
  • Genetic correlates of insight in schizophrenia. 
  • Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study. 
  • Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults. 
  • Genetic determinants of age-related macular degeneration in diverse populations from the PAGE study. 
  • Genetic determinants of childhood and adult height associated with osteosarcoma risk. 
  • Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium. 
  • Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis. 
  • Genetic determinants of serum testosterone concentrations in men. 
  • Genetic diagnosis in Lafora disease: genotype-phenotype correlations and diagnostic pitfalls. 
  • Genetic diversity is a predictor of mortality in humans. 
  • Genetic effects in the leukotriene biosynthesis pathway and association with atherosclerosis. 
  • Genetic elucidation of human hyperosmia to isovaleric acid. 
  • Genetic factors influencing prostate cancer risk in Norwegian men. 
  • Genetic heterogeneity of Alzheimer's disease in subjects with and without hypertension. 
  • Genetic influence of CCR5, CCR2, and SDF1 variants on human immunodeficiency virus 1 (HIV-1)-related disease progression and neurological impairment, in children with symptomatic HIV-1 infection. 
  • Genetic interactions drive heterogeneity in causal variant effect sizes for gene expression and complex traits. 
  • Genetic markers of suicidal ideation emerging during citalopram treatment of major depression. 
  • Genetic modifiers of the severity of sickle cell anemia identified through a genome-wide association study. 
  • Genetic pathway analysis reveals a major role for extracellular matrix organization in inflammatory and neuropathic pain. 
  • Genetic pleiotropy between age-related macular degeneration and 16 complex diseases and traits. 
  • Genetic polymorphisms and the risk of stroke after cardiac surgery. 
  • Genetic polymorphisms associated with priapism in sickle cell disease. 
  • Genetic polymorphisms in CYP17, CYP3A4, CYP19A1, SRD5A2, IGF-1, and IGFBP-3 and prostate cancer risk in African-American men: the Flint Men's Health Study. 
  • Genetic polymorphisms in DNA base-excision repair genes ADPRT, XRCC1, and APE1 and the risk of squamous cell carcinoma of the head and neck. 
  • Genetic polymorphisms modify bladder cancer recurrence and survival in a USA population-based prognostic study. 
  • Genetic polymorphisms of ataxia telangiectasia mutated and breast cancer risk. 
  • Genetic polymorphisms of metabolic enzymes and the pharmacokinetics of indapamide in Taiwanese subjects. 
  • Genetic polymorphisms of p21 and risk of second primary malignancy in patients with index squamous cell carcinoma of the head and neck. 
  • Genetic polymorphisms of p21 are associated with risk of squamous cell carcinoma of the head and neck. 
  • Genetic polymorphisms of the N-acetyltransferase genes and risk of Parkinson's disease. 
  • Genetic predisposition of behavioral response. 
  • Genetic predisposition to higher blood pressure increases coronary artery disease risk. 
  • Genetic predisposition to lung adenocarcinoma among never-smoking Chinese with different epidermal growth factor receptor mutation status. 
  • Genetic regulation of rejection and survival following human lung transplantation by the innate immune receptor CD14. 
  • Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. 
  • Genetic risk factors for perception of symptoms in GERD: an observational cohort study. 
  • Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide polymorphisms. 
  • Genetic sharing and heritability of paediatric age of onset autoimmune diseases. 
  • Genetic signatures in choline and 1-carbon metabolism are associated with the severity of hepatic steatosis. 
  • Genetic signatures of exceptional longevity in humans. 
  • Genetic studies of body mass index yield new insights for obesity biology. 
  • Genetic studies: look no further than your own backyard. 
  • Genetic susceptibility for chronic bronchitis in chronic obstructive pulmonary disease. 
  • Genetic susceptibility of lung cancer associated with common variants in the 3' untranslated regions of the adenosine triphosphate-binding cassette B1 (ABCB1) and ABCC1 candidate transporter genes for carcinogen export. 
  • Genetic susceptibility to hepatic steatosis. 
  • Genetic susceptibility variants for chronic lymphocytic leukemia. 
  • Genetic variant in DNA repair gene GTF2H4 is associated with lung cancer risk: a large-scale analysis of six published GWAS datasets in the TRICL consortium. 
  • Genetic variant of IRAK2 in the toll-like receptor signaling pathway and survival of non-small cell lung cancer. 
  • Genetic variant of PRKAA1 and gastric cancer risk in an eastern Chinese population. 
  • Genetic variant rs16430 6bp > 0bp at the microRNA-binding site in TYMS and risk of sporadic breast cancer risk in non-Hispanic white women aged ≤ 55 years. 
  • Genetic variant rs3750625 in the 3'UTR of ADRA2A affects stress-dependent acute pain severity after trauma and alters a microRNA-34a regulatory site. 
  • Genetic variant rs4072037 of MUC1 and gastric cancer risk in an Eastern Chinese population. 
  • Genetic variants affecting the neural processing of human facial expressions: evidence using a genome-wide functional imaging approach. 
  • Genetic variants and associations of 25-hydroxyvitamin D concentrations with major clinical outcomes. 
  • Genetic variants and cellular stressors associated with exfoliation syndrome modulate promoter activity of a lncRNA within the LOXL1 locus. 
  • Genetic variants and haplotypes of the caspase-8 and caspase-10 genes contribute to susceptibility to cutaneous melanoma. 
  • Genetic variants associated with development of TMD and its intermediate phenotypes: the genetic architecture of TMD in the OPPERA prospective cohort study. 
  • Genetic variants associated with patent ductus arteriosus in extremely preterm infants. 
  • Genetic variants associated with sepsis. 
  • Genetic variants associated with vein graft stenosis after coronary artery bypass grafting. 
  • Genetic variants at the miR-124 binding site on the cytoskeleton-organizing IQGAP1 gene confer differential predisposition to breast cancer. 
  • Genetic variants improve breast cancer risk prediction on mammograms. 
  • Genetic variants in ABCG1 are associated with survival of nonsmall-cell lung cancer patients. 
  • Genetic variants in CYP2B6 and HSD17B12 associated with risk of squamous cell carcinoma of the head and neck. 
  • Genetic variants in DDO and PEX5L in peroxisome-related pathways predict non-small cell lung cancer survival. 
  • Genetic variants in ELOVL2 and HSD17B12 predict melanoma-specific survival. 
  • Genetic variants in ERCC1 and XPC predict survival outcome of non-small cell lung cancer patients treated with platinum-based therapy. 
  • Genetic variants in GTF2H1 and risk of lung cancer: a case-control analysis in a Chinese population. 
  • Genetic variants in Hippo pathway genes YAP1, TEAD1 and TEAD4 are associated with melanoma-specific survival. 
  • Genetic variants in MGMT and risk of lung cancer in Southeastern Chinese: a haplotype-based analysis. 
  • Genetic variants in PDSS1 and SLC16A6 of the ketone body metabolic pathway predict cutaneous melanoma-specific survival. 
  • Genetic variants in RORA and DNMT1 associated with cutaneous melanoma survival. 
  • Genetic variants in RUNX3, AMD1 and MSRA in the methionine metabolic pathway and survival in nonsmall cell lung cancer patients. 
  • Genetic variants in TKT and DERA in the nicotinamide adenine dinucleotide phosphate pathway predict melanoma survival. 
  • Genetic variants in TNF-α promoter are predictors of recurrence in patients with squamous cell carcinoma of oropharynx after definitive radiotherapy. 
  • Genetic variants in fanconi anemia pathway genes BRCA2 and FANCA predict melanoma survival. 
  • Genetic variants in glutamine metabolic pathway genes predict cutaneous melanoma-specific survival. 
  • Genetic variants in miR-196a2 and miR-499 are associated with susceptibility to esophageal squamous cell carcinoma in Chinese Han population. 
  • Genetic variants in microRNA-binding sites of DNA repair genes as predictors of recurrence in patients with squamous cell carcinoma of the oropharynx. 
  • Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. 
  • Genetic variants in nucleotide excision repair pathway predict survival of esophageal squamous cell cancer patients receiving platinum-based chemotherapy. 
  • Genetic variants in peroxisome proliferator-activated receptor-gamma gene are associated with risk of lung cancer in a Chinese population. 
  • Genetic variants in selected pre-microRNA genes and the risk of squamous cell carcinoma of the head and neck. 
  • Genetic variants in telomerase-related genes are associated with an older age at diagnosis in glioma patients: evidence for distinct pathways of gliomagenesis. 
  • Genetic variants in the H2AFX promoter region are associated with risk of sporadic breast cancer in non-Hispanic white women aged  
  • Genetic variants in the PIWI-piRNA pathway gene DCP1A predict melanoma disease-specific survival. 
  • Genetic variants in the TEP1 gene are associated with prostate cancer risk and recurrence. 
  • Genetic variants in the calcium signaling pathway genes are associated with cutaneous melanoma-specific survival. 
  • Genetic variants in the folate metabolic pathway genes predict cutaneous melanoma-specific survival. 
  • Genetic variants in the genes encoding rho GTPases and related regulators predict cutaneous melanoma-specific survival. 
  • Genetic variants in the human leukocyte antigen region and survival of Chinese patients with non-small cell lung carcinoma. 
  • Genetic variants in the integrin signaling pathway genes predict cutaneous melanoma survival. 
  • Genetic variants in the liver kinase B1-AMP-activated protein kinase pathway genes and pancreatic cancer risk. 
  • Genetic variants in the metzincin metallopeptidase family genes predict melanoma survival. 
  • Genetic variants in the platelet-derived growth factor subunit B gene associated with pancreatic cancer risk. 
  • Genetic variants in the vitamin D pathway genes VDBP and RXRA modulate cutaneous melanoma disease-specific survival. 
  • Genetic variants near PDGFRA are associated with corneal curvature in Australians. 
  • Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration. 
  • Genetic variants of CHEK1, PRIM2 and CDK6 in the mitotic phase-related pathway are associated with nonsmall cell lung cancer survival. 
  • Genetic variants of DNA repair genes predict the survival of patients with esophageal squamous cell cancer receiving platinum-based adjuvant chemotherapy. 
  • Genetic variants of GADD45A, GADD45B and MAPK14 predict platinum-based chemotherapy-induced toxicities in Chinese patients with non-small cell lung cancer. 
  • Genetic variants of JNK and p38α pathways and risk of non-small cell lung cancer in an Eastern Chinese population. 
  • Genetic variants of NOXA and MCL1 modify the risk of HPV16-associated squamous cell carcinoma of the head and neck. 
  • Genetic variants of PTPN2 are associated with lung cancer risk: a re-analysis of eight GWASs in the TRICL-ILCCO consortium. 
  • Genetic variants of SDCCAG8 and MAGI2 in mitosis-related pathway genes are independent predictors of cutaneous melanoma-specific survival. 
  • Genetic variants of a BH3-only pro-apoptotic gene, PUMA, and risk of HPV16-associated squamous cell carcinoma of the head and neck. 
  • Genetic variants of genes in the NER pathway associated with risk of breast cancer: A large-scale analysis of 14 published GWAS datasets in the DRIVE study. 
  • Genetic variants of genes in the Notch signaling pathway predict overall survival of non-small cell lung cancer patients in the PLCO study. 
  • Genetic variants of p21 and p27 and pancreatic cancer risk in non-Hispanic Whites: a case-control study. 
  • Genetic variants of the LIN28B gene predict severe radiation pneumonitis in patients with non-small cell lung cancer treated with definitive radiation therapy. 
  • Genetic variants of the nonhomologous end joining gene LIG4 and severe radiation pneumonitis in nonsmall cell lung cancer patients treated with definitive radiotherapy. 
  • Genetic variants of the peroxisome proliferator-activated receptor (PPAR) signaling pathway genes and risk of pancreatic cancer. 
  • Genetic variants on chromosome 1q41 influence ocular axial length and high myopia. 
  • Genetic variants primarily associated with type 2 diabetes are related to coronary artery disease risk. 
  • Genetic variation associated with childhood and adult stature and risk of MYCN-amplified neuroblastoma. 
  • Genetic variation determines VEGF-A plasma levels in cancer patients. 
  • Genetic variation in HTR2A influences serotonin transporter binding potential as measured using PET and [11C]DASB. 
  • Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance. 
  • Genetic variation in IL28B: impact on drug development for chronic hepatitis C infection. 
  • Genetic variation in MDM2 and p14ARF and susceptibility to salivary gland carcinoma. 
  • Genetic variation in PEAR1 is associated with platelet aggregation and cardiovascular outcomes. 
  • Genetic variation in TYMS in the one-carbon transfer pathway is associated with ovarian carcinoma types in the Ovarian Cancer Association Consortium. 
  • Genetic variation in a human odorant receptor alters odour perception. 
  • Genetic variation in adiponectin (ADIPOQ) and the type 1 receptor (ADIPOR1), obesity and prostate cancer in African Americans. 
  • Genetic variation in glutathione S-transferase omega-1, arsenic methyltransferase and methylene-tetrahydrofolate reductase, arsenic exposure and bladder cancer: a case-control study. 
  • Genetic variation in heat shock protein 60 gene and coronary heart disease in China: tagging-SNP haplotype analysis in a case-control study. 
  • Genetic variation in human NPY expression affects stress response and emotion. 
  • Genetic variation in insulin-like growth factor 2 may play a role in ovarian cancer risk. 
  • Genetic variation in the PNPLA3 gene and hepatocellular carcinoma in USA: risk and prognosis prediction. 
  • Genetic variation in the body mass index of adult survivors of childhood acute lymphoblastic leukemia: A report from the Childhood Cancer Survivor Study and the St. Jude Lifetime Cohort. 
  • Genetic variation in the dectin-1/CARD9 recognition pathway and susceptibility to candidemia. 
  • Genetic variation in the odorant receptor OR2J3 is associated with the ability to detect the "grassy" smelling odor, cis-3-hexen-1-ol. 
  • Genetic variation in the one-carbon transfer pathway and ovarian cancer risk. 
  • Genetic variation in the prostaglandin E2 pathway is associated with primary graft dysfunction. 
  • Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. 
  • Genetic variations in TERT-CLPTM1L genes and risk of squamous cell carcinoma of the head and neck. 
  • Genetic variations in the homologous recombination repair pathway genes modify risk of glioma. 
  • Genetic variations in the mTOR gene contribute toward gastric adenocarcinoma susceptibility in an Eastern Chinese population. 
  • Genetic variations of mTORC1 genes and risk of gastric cancer in an Eastern Chinese population. 
  • Genetic variations of the ADIPOQgene and risk of prostate cancer in Chinese Han men. 
  • Genetic, epigenetic, and environmental factors controlling oxytocin receptor gene expression. 
  • Genetically Determined Plasma Lipid Levels and Risk of Diabetic Retinopathy: A Mendelian Randomization Study. 
  • Genetically Informed Prostate Cancer Screening. 
  • Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity. 
  • Genetically low vitamin D concentrations and myopic refractive error: a Mendelian randomization study. 
  • Genetically predicted body mass index and Alzheimer's disease-related phenotypes in three large samples: Mendelian randomization analyses. 
  • Genetically predicted circulating protein biomarkers and ovarian cancer risk. 
  • Genetics in heart failure: practical incorporation of this new biologic dimension. 
  • Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study. 
  • Genetics of drought adaptation in Arabidopsis thaliana II. QTL analysis of a new mapping population, KAS-1 x TSU-1. 
  • Genetics of physiological dysregulation: findings from the long life family study using joint models. 
  • GenoWatch: a disease gene mining browser for association study. 
  • Genome Sequencing of Arabidopsis abp1-5 Reveals Second-Site Mutations That May Affect Phenotypes. 
  • Genome sequencing unveils a regulatory landscape of platelet reactivity. 
  • Genome-Wide Analysis of Sex Disparities in the Genetic Architecture of Lung and Colorectal Cancers. 
  • Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans. 
  • Genome-Wide Association Meta-Analysis Reveals Novel Juvenile Idiopathic Arthritis Susceptibility Loci. 
  • Genome-Wide Association Study Links Receptor Tyrosine Kinase Inhibitor Sprouty 2 to Thrombocytopenia after Coronary Artery Bypass Surgery. 
  • Genome-Wide Association Study Meta-Analysis of Long-Term Average Blood Pressure in East Asians. 
  • Genome-Wide Association Study Meta-Analysis of Stroke in 22 000 Individuals of African Descent Identifies Novel Associations With Stroke. 
  • Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts. 
  • Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium. 
  • Genome-Wide Interactions with Dairy Intake for Body Mass Index in Adults of European Descent. 
  • Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types. 
  • Genome-Wide Meta-Analysis of Longitudinal Alcohol Consumption Across Youth and Early Adulthood. 
  • Genome-wide Analysis Identifies Novel Loci Associated with Ovarian Cancer Outcomes: Findings from the Ovarian Cancer Association Consortium. 
  • Genome-wide Association Meta-analysis of Childhood and Adolescent Internalizing Symptoms. 
  • Genome-wide Association Study of Platelet Count Identifies Ancestry-Specific Loci in Hispanic/Latino Americans. 
  • Genome-wide Meta-analysis on the Sense of Smell Among US Older Adults. 
  • Genome-wide analysis identifies 12 loci influencing human reproductive behavior. 
  • Genome-wide analysis identifies novel susceptibility loci for myocardial infarction. 
  • Genome-wide analysis of central corneal thickness in primary open-angle glaucoma cases in the NEIGHBOR and GLAUGEN consortia. 
  • Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities. 
  • Genome-wide analysis of genetic predisposition to common polygenic cancers. 
  • Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma. 
  • Genome-wide architecture of reproductive isolation in a naturally occurring hybrid zone between Mus musculus musculus and M. m. domesticus. 
  • Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression. 
  • Genome-wide association analyses identify three new susceptibility loci for primary angle closure glaucoma. 
  • Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma. 
  • Genome-wide association analysis identifies TYW3/CRYZ and NDST4 loci associated with circulating resistin levels. 
  • Genome-wide association analysis identifies a meningioma risk locus at 11p15.5. 
  • Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk. 
  • Genome-wide association analysis identifies six new loci associated with forced vital capacity. 
  • Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits. 
  • Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations. 
  • Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. 
  • Genome-wide association for smoking cessation success in a trial of precessation nicotine replacement. 
  • Genome-wide association for smoking cessation success: participants in a trial with adjunctive denicotinized cigarettes. 
  • Genome-wide association identifies ATOH7 as a major gene determining human optic disc size. 
  • Genome-wide association identifies diverse causes of common variable immunodeficiency. 
  • Genome-wide association meta-analyses to identify common genetic variants associated with hallux valgus in Caucasian and African Americans. 
  • Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error. 
  • Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence. 
  • Genome-wide association meta-analysis of corneal curvature identifies novel loci and shared genetic influences across axial length and refractive error. 
  • Genome-wide association of body fat distribution in African ancestry populations suggests new loci. 
  • Genome-wide association of familial prostate cancer cases identifies evidence for a rare segregating haplotype at 8q24.21. 
  • Genome-wide association of pericardial fat identifies a unique locus for ectopic fat. 
  • Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations. 
  • Genome-wide association reveals contribution of MRAS to painful temporomandibular disorder in males. 
  • Genome-wide association scan for variants associated with early-onset prostate cancer. 
  • Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction. 
  • Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans. 
  • Genome-wide association studies identify susceptibility loci for epithelial ovarian cancer in east Asian women. 
  • Genome-wide association studies in Asians confirm the involvement of ATOH7 and TGFBR3, and further identify CARD10 as a novel locus influencing optic disc area. 
  • Genome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference. 
  • Genome-wide association studies in asthma: what they really told us about pathogenesis. 
  • Genome-wide association studies of alcohol dependence, DSM-IV criterion count and individual criteria. 
  • Genome-wide association studies of the PR interval in African Americans. 
  • Genome-wide association studies reveal genetic variants in CTNND2 for high myopia in Singapore Chinese. 
  • Genome-wide association study (GWAS) of human host factors influencing viral severity of herpes simplex virus type 2 (HSV-2). 
  • Genome-wide association study and meta-analysis of intraocular pressure. 
  • Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease. 
  • Genome-wide association study evaluating single-nucleotide polymorphisms and outcomes in patients with advanced stage serous ovarian or primary peritoneal cancer: An NRG Oncology/Gynecologic Oncology Group study. 
  • Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation. 
  • Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction. 
  • Genome-wide association study identifies FCGR2A as a susceptibility locus for Kawasaki disease. 
  • Genome-wide association study identifies HLA 8.1 ancestral haplotype alleles as major genetic risk factors for myositis phenotypes. 
  • Genome-wide association study identifies WNT7B as a novel locus for central corneal thickness in Latinos. 
  • Genome-wide association study identifies ZFHX1B as a susceptibility locus for severe myopia. 
  • Genome-wide association study identifies a maternal copy-number deletion in PSG11 enriched among preeclampsia patients. 
  • Genome-wide association study identifies a missense variant at APOA5 for coronary artery disease in Multi-Ethnic Cohorts from Southeast Asia. 
  • Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3. 
  • Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India. 
  • Genome-wide association study identifies a novel locus for cannabis dependence. 
  • Genome-wide association study identifies a novel susceptibility locus at 6p21.3 among familial CLL. 
  • Genome-wide association study identifies germline polymorphisms associated with relapse of childhood acute lymphoblastic leukemia. 
  • Genome-wide association study identifies loci associated with liability to alcohol and drug dependence that is associated with variability in reward-related ventral striatum activity in African- and European-Americans. 
  • Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. 
  • Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia. 
  • Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer. 
  • Genome-wide association study identifies new susceptibility loci for epithelial ovarian cancer in Han Chinese women. 
  • Genome-wide association study identifies nidogen 1 (NID1) as a susceptibility locus to cutaneous nevi and melanoma risk. 
  • Genome-wide association study identifies novel alleles associated with risk of cutaneous basal cell carcinoma and squamous cell carcinoma. 
  • Genome-wide association study identifies novel loci predisposing to cutaneous melanoma. 
  • Genome-wide association study identifies seven novel susceptibility loci for primary open-angle glaucoma. 
  • Genome-wide association study identifies three new melanoma susceptibility loci. 
  • Genome-wide association study identifies three susceptibility loci for laryngeal squamous cell carcinoma in the Chinese population. 
  • Genome-wide association study implicates a chromosome 12 risk locus for late-onset Alzheimer disease. 
  • Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels. 
  • Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci. 
  • Genome-wide association study meta-analysis reveals transethnic replication of mean arterial and pulse pressure loci. 
  • Genome-wide association study of Lp-PLA(2) activity and mass in the Framingham Heart Study. 
  • Genome-wide association study of Parkinson's disease in East Asians. 
  • Genome-wide association study of acute kidney injury after coronary bypass graft surgery identifies susceptibility loci. 
  • Genome-wide association study of alcohol use disorder identification test (AUDIT) scores in 20 328 research participants of European ancestry. 
  • Genome-wide association study of bipolar I disorder in the Han Chinese population. 
  • Genome-wide association study of circulating interleukin 6 levels identifies novel loci. 
  • Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. 
  • Genome-wide association study of dermatomyositis reveals genetic overlap with other autoimmune disorders. 
  • Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors. 
  • Genome-wide association study of interferon-related cytopenia in chronic hepatitis C patients. 
  • Genome-wide association study of intraocular pressure identifies the GLCCI1/ICA1 region as a glaucoma susceptibility locus. 
  • Genome-wide association study of new-onset atrial fibrillation after coronary artery bypass grafting surgery. 
  • Genome-wide association study of obsessive-compulsive disorder. 
  • Genome-wide association study of posttraumatic stress disorder in a cohort of Iraq-Afghanistan era veterans. 
  • Genome-wide association study of prostate cancer in men of African ancestry identifies a susceptibility locus at 17q21. 
  • Genome-wide association study of red blood cell traits in Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos. 
  • Genome-wide association study of retinopathy in individuals without diabetes. 
  • Genome-wide association study of sepsis in extremely premature infants. 
  • Genome-wide association study of severity in multiple sclerosis. 
  • Genome-wide association study of smoking behaviours in patients with COPD. 
  • Genome-wide association study of subcortical brain volume in PTSD cases and trauma-exposed controls. 
  • Genome-wide association study of subtype-specific epithelial ovarian cancer risk alleles using pooled DNA. 
  • Genome-wide association study of suicidal ideation emerging during citalopram treatment of depressed outpatients. 
  • Genome-wide association study of suicide attempts in mood disorder patients. 
  • Genome-wide association study of treatment refractory schizophrenia in Han Chinese. 
  • Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT). 
  • Genome-wide association study of young-onset hypertension in the Han Chinese population of Taiwan. 
  • Genome-wide association study on progression of carotid artery intima media thickness over 10 years in a Chinese cohort. 
  • Genome-wide association study reveals novel genetic determinants of DNA repair capacity in lung cancer. 
  • Genome-wide association study validation identifies novel loci for atherosclerotic cardiovascular disease. 
  • Genome-wide copy number analysis using copy number inferring tool (CNIT) and DNA pooling. 
  • Genome-wide detection and characterization of positive selection in human populations. 
  • Genome-wide gene-environment interaction analysis for asbestos exposure in lung cancer susceptibility. 
  • Genome-wide high resolution DNA profiling of hairy cell leukaemia. 
  • Genome-wide high-density SNP linkage search for glioma susceptibility loci: results from the Gliogene Consortium. 
  • Genome-wide high-resolution mapping of UV-induced mitotic recombination events in Saccharomyces cerevisiae. 
  • Genome-wide high-resolution mapping of chromosome fragile sites in Saccharomyces cerevisiae. 
  • Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder. 
  • Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function. 
  • Genome-wide linkage analysis of cardiovascular disease biomarkers in a large, multigenerational family. 
  • Genome-wide linkage analysis of carotid artery traits in exceptionally long-lived families. 
  • Genome-wide linkage analysis of quantitative biomarker traits of osteoarthritis in a large, multigenerational extended family. 
  • Genome-wide linkage scan in fuchs endothelial corneal dystrophy. 
  • Genome-wide linkage screen in familial Parkinson disease identifies loci on chromosomes 3 and 18. 
  • Genome-wide mapping for clinically relevant predictors of lamotrigine- and phenytoin-induced hypersensitivity reactions. 
  • Genome-wide mapping of spontaneous genetic alterations in diploid yeast cells. 
  • Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies. 
  • Genome-wide meta-analyses identifies novel taxane-induced peripheral neuropathy-associated loci. 
  • Genome-wide meta-analyses identify multiple loci associated with smoking behavior. 
  • Genome-wide meta-analyses of smoking behaviors in African Americans. 
  • Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries. 
  • Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. 
  • Genome-wide meta-analysis of cerebral white matter hyperintensities in patients with stroke. 
  • Genome-wide meta-analysis of five Asian cohorts identifies PDGFRA as a susceptibility locus for corneal astigmatism. 
  • Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium. 
  • Genome-wide meta-analysis of myopia and hyperopia provides evidence for replication of 11 loci. 
  • Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake. 
  • Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia. 
  • Genome-wide scan of copy number variation in late-onset Alzheimer's disease. 
  • Genome-wide scan reveals signatures of selection related to pollution adaptation in non-model estuarine Atlantic killifish (Fundulus heteroclitus). 
  • Genome-wide significant risk associations for mucinous ovarian carcinoma. 
  • Genome-wide study of methotrexate clearance replicates SLCO1B1. 
  • Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. 
  • Genomewide Association Scan of a Mortality Associated Endophenotype for a Long and Healthy Life in the Long Life Family Study. 
  • Genomewide Association Study of Platelet Reactivity and Cardiovascular Response in Patients Treated With Clopidogrel: A Study by the International Clopidogrel Pharmacogenomics Consortium. 
  • Genomewide Meta-Analysis Validates a Role for S1PR1 in Microtubule Targeting Agent-Induced Sensory Peripheral Neuropathy. 
  • Genomewide association studies of suicide attempts in US soldiers. 
  • Genomewide investigation of adaptation to harmful algal blooms in common bottlenose dolphins (Tursiops truncatus). 
  • Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs. 
  • Genomic Analysis of Germline Variation Associated with Survival of Patients with Colorectal Cancer Treated with Chemotherapy Plus Biologics in CALGB/SWOG 80405 (Alliance). 
  • Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk. 
  • Genomic ancestry and somatic alterations correlate with age at diagnosis in Hispanic children with B-cell acute lymphoblastic leukemia. 
  • Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation. 
  • Genomic characterization of HER2-positive breast cancer and response to neoadjuvant trastuzumab and chemotherapy-results from the ACOSOG Z1041 (Alliance) trial. 
  • Genomic complexity identifies patients with aggressive chronic lymphocytic leukemia. 
  • Genomic correlates of glatiramer acetate adverse cardiovascular effects lead to a novel locus mediating coronary risk. 
  • Genomic correlates of variability in immune response to an oral cholera vaccine. 
  • Genomic lesions associated with a different clinical outcome in diffuse large B-Cell lymphoma treated with R-CHOP-21. 
  • Genomic locus modulating corneal thickness in the mouse identifies POU6F2 as a potential risk of developing glaucoma. 
  • Genomic predictors of the maximal O₂ uptake response to standardized exercise training programs. 
  • Genomic profiles specific to patient ethnicity in lung adenocarcinoma. 
  • Genomic resources for the endangered Hawaiian honeycreepers. 
  • Genomic sequencing is required for identification of tuberculosis transmission in Hawaii. 
  • Genomics of human health and aging. 
  • Genotypes and haplotypes of the VEGF gene and survival in locally advanced non-small cell lung cancer patients treated with chemoradiotherapy. 
  • Genotyping Array Design and Data Quality Control in the Million Veteran Program. 
  • Germline polymorphisms in an enhancer of PSIP1 are associated with progression-free survival in epithelial ovarian cancer. 
  • Glaucoma Genetic Risk Scores in the Million Veteran Program. 
  • Glioma risk associated with extent of estimated European genetic ancestry in African Americans and Hispanics. 
  • Global Survey of Variation in a Human Olfactory Receptor Gene Reveals Signatures of Non-Neutral Evolution. 
  • Global analysis of genomic instability caused by DNA replication stress in Saccharomyces cerevisiae. 
  • Glucocorticoid Receptor (NR3C1) Gene Polymorphism Moderate Intervention Effects on the Developmental Trajectory of African-American Adolescent Alcohol Abuse. 
  • Glucose metabolism gene polymorphisms and clinical outcome in pancreatic cancer. 
  • Glutathione S-transferase omega-1 modifies age-at-onset of Alzheimer disease and Parkinson disease. 
  • Glycine and a glycine dehydrogenase (GLDC) SNP as citalopram/escitalopram response biomarkers in depression: pharmacometabolomics-informed pharmacogenomics. 
  • Great ape genetic diversity and population history. 
  • HDL-cholesterol levels and risk of age-related macular degeneration: a multiethnic genetic study using Mendelian randomization. 
  • HDMX regulates p53 activity and confers chemoresistance to 3-bis(2-chloroethyl)-1-nitrosourea. 
  • HLA-A*3101 and carbamazepine-induced hypersensitivity reactions in Europeans. 
  • HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol. 
  • HNF-4alpha: from MODY to late-onset type 2 diabetes. 
  • HOXB13 is a susceptibility gene for prostate cancer: results from the International Consortium for Prostate Cancer Genetics (ICPCG). 
  • HPA axis genetic variation, pubertal status, and sex interact to predict amygdala and hippocampus responses to negative emotional faces in school-age children. 
  • HSPB1 gene polymorphisms predict risk of mortality for US patients after radio(chemo)therapy for non-small cell lung cancer. 
  • Haploidization in Saccharomyces cerevisiae induced by a deficiency in homologous recombination. 
  • Haplotype associations with quantitative traits in the presence of complex multilocus and heterogeneous effects. 
  • Haplotype of N-acetyltransferase 1 and 2 and risk of pancreatic cancer. 
  • Haplotype of signal transducer and activator of transcription 3 gene predicts cardiovascular disease in dialysis patients. 
  • Haplotype-based analysis: a summary of GAW16 Group 4 analysis. 
  • Haplotypes spanning the complement factor H gene are protective against age-related macular degeneration. 
  • Heavy metals, organic solvents, and multiple sclerosis: An exploratory look at gene-environment interactions. 
  • Hepatocyte growth factor and myopia: genetic association analyses in a Caucasian population. 
  • Hepatocyte growth factor and retinal arteriolar diameter in Singapore Chinese. 
  • Hereditary link: scientists seek clues in genetic risks for prostate cancer. 
  • Heritable individual-specific and allele-specific chromatin signatures in humans. 
  • Heritable variation at the chromosome 21 gene ERG is associated with acute lymphoblastic leukemia risk in children with and without Down syndrome. 
  • Hidden heterogeneity in Alzheimer's disease: Insights from genetic association studies and other analyses. 
  • High-Density Genotypes of Inbred Mouse Strains: Improved Power and Precision of Association Mapping. 
  • High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4 gene region in autism susceptibility. 
  • High-density single nucleotide polymorphism screen in a large multiplex neural tube defect family refines linkage to loci at 7p21.1-pter and 2q33.1-q35. 
  • High-resolution genome-wide analysis of irradiated (UV and γ-rays) diploid yeast cells reveals a high frequency of genomic loss of heterozygosity (LOH) events. 
  • High-throughput genotyping with single nucleotide polymorphisms. 
  • High-throughput multimodal automated phenotyping (MAP) with application to PheWAS. 
  • Higher magnesium intake is associated with lower fasting glucose and insulin, with no evidence of interaction with select genetic loci, in a meta-analysis of 15 CHARGE Consortium Studies. 
  • Host Genetic Variant in CXCL16 May Be Associated With Hepatitis B Virus-Related Acute Liver Failure. 
  • Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections. 
  • Human Genetic Variability Contributes to Postoperative Morphine Consumption. 
  • Human catechol-O-methyltransferase haplotypes modulate protein expression by altering mRNA secondary structure. 
  • Human choline transporter gene variation is associated with corticolimbic reactivity and autonomic-cholinergic function. 
  • Human complement factor H Y402H polymorphism causes an age-related macular degeneration phenotype and lipoprotein dysregulation in mice. 
  • Human genetic and metabolite variation reveals that methylthioadenosine is a prognostic biomarker and an inflammatory regulator in sepsis. 
  • Human genetic variation in VAC14 regulates Salmonella invasion and typhoid fever through modulation of cholesterol. 
  • Human genomic regions with exceptionally high levels of population differentiation identified from 911 whole-genome sequences. 
  • Human-Mediated Admixture and Selection Shape the Diversity on the Modern Swine (Sus scrofa) Y Chromosomes. 
  • Hypercoagulable states in cardiovascular disease. 
  • Hypertension genes and retinal vascular calibre: the Cardiovascular Health Study. 
  • Hypothesis-independent pathway analysis implicates GABA and acetyl-CoA metabolism in primary open-angle glaucoma and normal-pressure glaucoma. 
  • IGF2R genetic variants, circulating IGF2 concentrations and colon cancer risk in African Americans and Whites. 
  • IL28B gene polymorphisms and viral kinetics in HIV/hepatitis C virus-coinfected patients treated with pegylated interferon and ribavirin. 
  • IL28B rs12979860 is not associated with histologic features of NAFLD in a cohort of Caucasian North American patients. 
  • ITPA gene polymorphisms significantly affect hemoglobin decline and treatment outcomes in patients coinfected with HIV and HCV. 
  • ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C. 
  • Identical twins carry a persistent epigenetic signature of early genome programming. 
  • Identification and Quantitation of Coding Variants and Isoforms of Pulmonary Surfactant Protein A. 
  • Identification and activity of the functional complex between hnRNPL and the pseudoexfoliation syndrome-associated lncRNA, LOXL1-AS1. 
  • Identification and characterization of novel SNPs in CHEK2 in Ashkenazi Jewish men with prostate cancer. 
  • Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus. 
  • Identification and functional characterization of JWA polymorphisms and their association with risk of gastric cancer and esophageal squamous cell carcinoma in a Chinese population. 
  • Identification and functional study of a mild allele of SlDELLA gene conferring the potential for improved yield in tomato. 
  • Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31. 
  • Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer. 
  • Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. 
  • Identification of Functional and Expression Polymorphisms Associated With Risk for Antineutrophil Cytoplasmic Autoantibody-Associated Vasculitis. 
  • Identification of Novel, Replicable Genetic Risk Loci for Suicidal Thoughts and Behaviors Among US Military Veterans. 
  • Identification of Reduced ERAP2 Expression and a Novel HLA Allele as Components of a Risk Score for Susceptibility to Liver Injury Due to Amoxicillin-Clavulanate. 
  • Identification of a Locus Near ULK1 Associated With Progression-Free Survival in Ovarian Cancer. 
  • Identification of a candidate gene for astigmatism. 
  • Identification of a melanoma susceptibility locus and somatic mutation in TET2. 
  • Identification of a novel susceptibility locus for juvenile idiopathic arthritis by genome-wide association analysis. 
  • Identification of a structurally distinct CD101 molecule encoded in the 950-kb Idd10 region of NOD mice. 
  • Identification of genetic polymorphisms associated with risk for pulmonary hypertension in sickle cell disease. 
  • Identification of genetic variants in base excision repair pathway and their associations with risk of esophageal squamous cell carcinoma. 
  • Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. 
  • Identification of hemoglobin Q India (alpha 1-64 Asp-His) through ARMS-PCR. First report from Pakistan. 
  • Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus. 
  • Identification of myopia-associated WNT7B polymorphisms provides insights into the mechanism underlying the development of myopia. 
  • Identification of new genetic variants of HLA-DQB1 associated with human longevity and lipid homeostasis-a cross-sectional study in a Chinese population. 
  • Identification of new susceptibility loci for IgA nephropathy in Han Chinese. 
  • Identification of novel candidate risk genes for myelomeningocele within the glucose homeostasis/oxidative stress and folate/one-carbon metabolism networks. 
  • Identification of novel epithelial ovarian cancer loci in women of African ancestry. 
  • Identification of novel interaction sites that determine specificity between fibroblast growth factor homologous factors and voltage-gated sodium channels. 
  • Identification of novel mutations and sequence variants in the SOX2 and CHX10 genes in patients with anophthalmia/microphthalmia. 
  • Identification of novel susceptibility Loci for kawasaki disease in a Han chinese population by a genome-wide association study. 
  • Identification of p18 INK4c as a tumor suppressor gene in glioblastoma multiforme. 
  • Identification of polymorphisms in cancer patients that differentially affect survival with age. 
  • Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations. 
  • Identification of seven new prostate cancer susceptibility loci through a genome-wide association study. 
  • Identification of significant association and gene-gene interaction of GABA receptor subunit genes in autism. 
  • Identification of six new susceptibility loci for invasive epithelial ovarian cancer. 
  • Identification of the single base change causing the callipyge muscle hypertrophy phenotype, the only known example of polar overdominance in mammals. 
  • Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry. 
  • Identifying susceptibility genes for prostate cancer--a family-based association study of polymorphisms in CYP17, CYP19, CYP11A1, and LH-beta. 
  • Immunochip SNP array identifies novel genetic variants conferring susceptibility to candidaemia. 
  • Immunologic aspects of monoclonal B-cell lymphocytosis. 
  • Impact of EGF, IL28B, and PNPLA3 polymorphisms on the outcome of allograft hepatitis C: a multicenter study. 
  • Impact of IL28B gene polymorphisms on interferon-λ3 plasma levels during pegylated interferon-α/ribavirin therapy for chronic hepatitis C in patients coinfected with HIV. 
  • Impact of Rare and Common Genetic Variants on Diabetes Diagnosis by Hemoglobin A1c in Multi-Ancestry Cohorts: The Trans-Omics for Precision Medicine Program. 
  • Impact of ancestry and common genetic variants on QT interval in African Americans. 
  • Impact of gene variants on sex-specific regulation of human Scavenger receptor class B type 1 (SR-BI) expression in liver and association with lipid levels in a population-based study. 
  • Impact of measurement error on testing genetic association with quantitative traits. 
  • Impact of psychological stress on the associations between apolipoprotein E variants and metabolic traits: findings in an American sample of caregivers and controls. 
  • Improving breast cancer risk prediction by using demographic risk factors, abnormality features on mammograms and genetic variants. 
  • Improving indel detection specificity of the Ion Torrent PGM benchtop sequencer. 
  • Impulsivity and genetic variants in DRD2 and ANKK1 moderate longitudinal associations between sleep problems and overweight from ages 5 to 11. 
  • Incorporating privileged genetic information for fundus image based glaucoma detection. 
  • Incorporating single-nucleotide polymorphisms into the Lyman model to improve prediction of radiation pneumonitis. 
  • Increased corpus callosum volume in children with chromosome 22q11.2 deletion syndrome is associated with neurocognitive deficits and genetic polymorphisms. 
  • Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers. 
  • Increased mutation and gene conversion within human segmental duplications. 
  • Increased parenchymal damage and steatohepatitis in Caucasian non-alcoholic fatty liver disease patients with common IL1B and IL6 polymorphisms. 
  • Independent associations of TOMM40 and APOE variants with body mass index. 
  • Independent effects of complement factor H Y402H polymorphism and cigarette smoking on risk of age-related macular degeneration. 
  • Independent evidence for an association between general cognitive ability and a genetic locus for educational attainment. 
  • Individual common variants exert weak effects on the risk for autism spectrum disorders. 
  • Individualized therapy for hepatitis C infection: focus on the interleukin-28B polymorphism in directing therapy. 
  • Inflammation, complement factor h, and age-related macular degeneration: the Multi-ethnic Study of Atherosclerosis. 
  • Inflammatory Protein Profiles in Plasma of Candidaemia Patients and the Contribution of Host Genetics to Their Variability. 
  • Inflammatory gene polymorphisms and risk of postoperative myocardial infarction after cardiac surgery. 
  • Influence of CYP2C19*2 and *3 loss-of-function alleles on the pharmacodynamic effects of standard- and high-dose clopidogrel in East Asians undergoing percutaneous coronary intervention: the results of the ACCEL-DOUBLE-2N3 study. 
  • Influence of HLA-C expression level on HIV control. 
  • Influence of genetic polymorphisms on platelet function, response to antiplatelet drugs and clinical outcomes in patients with coronary artery disease. 
  • Influence of interleukin-28B single-nucleotide polymorphisms on progression to liver cirrhosis in human immunodeficiency virus-hepatitis C virus-coinfected patients receiving antiretroviral therapy. 
  • Influence of obesity-related risk factors in the aetiology of glioma. 
  • Influence of platelet reactivity on BARC classification in East Asian patients undergoing percutaneous coronary intervention. Results of the ACCEL-BLEED study. 
  • Influence of psychological factors on risk of temporomandibular disorders. 
  • Influence of single nucleotide polymorphisms in the MMP1 promoter region on cutaneous melanoma progression. 
  • Inherited determinants of ovarian cancer survival. 
  • Inherited genetic susceptibility to acute lymphoblastic leukemia in Down syndrome. 
  • Inherited variant on chromosome 11q23 increases susceptibility to IDH-mutated but not IDH-normal gliomas regardless of grade or histology. 
  • Inherited variants affecting RNA editing may contribute to ovarian cancer susceptibility: results from a large-scale collaboration. 
  • Inherited variants in mitochondrial biogenesis genes may influence epithelial ovarian cancer risk. 
  • Inherited variants in regulatory T cell genes and outcome of ovarian cancer. 
  • Insight in glioma susceptibility through an analysis of 6p22.3, 12p13.33-12.1, 17q22-23.2 and 18q23 SNP genotypes in familial and non-familial glioma. 
  • Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis. 
  • Insulin-like growth factor axis gene polymorphisms and clinical outcomes in pancreatic cancer. 
  • Insulin-like growth factor axis gene polymorphisms modify risk of pancreatic cancer. 
  • Integrated genetic analyses revealed novel human longevity loci and reduced risks of multiple diseases in a cohort study of 15,651 Chinese individuals. 
  • Integrated genomic analyses in bronchopulmonary dysplasia. 
  • Integrated genomic profiling of chronic lymphocytic leukemia identifies subtypes of deletion 13q14. 
  • Integrated pathway and epistasis analysis reveals interactive effect of genetic variants at TERF1 and AFAP1L2 loci on melanoma risk. 
  • Integrating common and rare genetic variation in diverse human populations. 
  • Integrating genetic and gene expression evidence into genome-wide association analysis of gene sets. 
  • Integrating sequence and array data to create an improved 1000 Genomes Project haplotype reference panel. 
  • Integration of GWAS SNPs and tissue specific expression profiling reveal discrete eQTLs for human traits in blood and brain. 
  • Integration of Population-Level Genotype Data with Functional Annotation Reveals Over-Representation of Long Noncoding RNAs at Ovarian Cancer Susceptibility Loci. 
  • Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of Paclitaxel-induced sensory peripheral neuropathy. 
  • Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function. 
  • Integration of molecular diagnostics with therapeutics: implications for drug discovery and patient care. 
  • Integrative annotation of variants from 1092 humans: application to cancer genomics. 
  • Integrative genomics identifies RAB23 as an invasion mediator gene in diffuse-type gastric cancer. 
  • Integrative molecular profiling of routine clinical prostate cancer specimens. 
  • Inter-chromosomal level of genome organization and longevity-related phenotypes in humans. 
  • Inter-individual differences in baseline coagulation activities and their implications for international normalized ratio control during warfarin initiation therapy. 
  • Interaction Between Peroxisome Proliferator Activated Receptor δ and Epithelial Membrane Protein 2 Polymorphisms Influences HDL-C Levels in the Chinese Population. 
  • Interaction between serotonin transporter polymorphism (5-HTTLPR) and stressful life events in adolescents' trajectories of anxious/depressed symptoms. 
  • Interaction between the alpha-T catenin gene (VR22) and APOE in Alzheimer's disease. 
  • Interaction of FKBP5 gene variants and adverse life events in predicting depression onset: results from a 10-year prospective community study. 
  • Interaction of Sirtuin 1 (SIRT1) candidate longevity gene and particulate matter (PM2.5) on all-cause mortality: a longitudinal cohort study in China. 
  • Interaction of methylation-related genetic variants with circulating fatty acids on plasma lipids: a meta-analysis of 7 studies and methylation analysis of 3 studies in the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium. 
  • Interaction of the cytochrome P4501A2, SULT1A1 and NAT gene polymorphisms with smoking and dietary mutagen intake in modification of the risk of pancreatic cancer. 
  • Interactions Between Anandamide and Corticotropin-Releasing Factor Signaling Modulate Human Amygdala Function and Risk for Anxiety Disorders: An Imaging Genetics Strategy for Modeling Molecular Interactions. 
  • Interactions of dietary whole-grain intake with fasting glucose- and insulin-related genetic loci in individuals of European descent: a meta-analysis of 14 cohort studies. 
  • Interethnic analyses of blood pressure loci in populations of East Asian and European descent. 
  • Interferon-lambda genotype and low serum low-density lipoprotein cholesterol levels in patients with chronic hepatitis C infection. 
  • Intergenerational continuity in parents' and adolescents' externalizing problems: The role of life events and their interaction with GABRA2. 
  • Interleukin 1 receptor antagonist (IL1RN) gene variants predict radiographic severity of knee osteoarthritis and risk of incident disease. 
  • Interleukin 12B (IL12B) genetic variation and pulmonary tuberculosis: a study of cohorts from The Gambia, Guinea-Bissau, United States and Argentina. 
  • Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis. 
  • Interleukin-10 promoter variants predict HPV-positive tumors and survival of squamous cell carcinoma of the oropharynx. 
  • Interleukin-1β gene variants are associated with QTc interval prolongation following cardiac surgery: a prospective observational study. 
  • Interleukin-28B gene polymorphisms do not influence the susceptibility to HIV-infection or CD4 cell decline. 
  • Interleukin-28B polymorphism improves viral kinetics and is the strongest pretreatment predictor of sustained virologic response in genotype 1 hepatitis C virus. 
  • Interplay between stress-related genes may influence Alzheimer's disease development: The results of genetic interaction analyses of human data. 
  • Interpretation and reporting of large regions of homozygosity and suspected consanguinity/uniparental disomy, 2021 revision: A technical standard of the American College of Medical Genetics and Genomics (ACMG). 
  • Interrogation of the platelet-derived growth factor receptor alpha locus and corneal astigmatism in Australians of Northern European ancestry: results of a genome-wide association study. 
  • Inverse association of female hormone replacement therapy with age-related macular degeneration and interactions with ARMS2 polymorphisms. 
  • Investigating the genetic architecture of noncognitive skills using GWAS-by-subtraction. 
  • Investigation of known genetic risk factors for primary open angle glaucoma in two populations of African ancestry. 
  • Investigation of potential gene-gene interactions between APOE and RELN contributing to autism risk. 
  • Investigation of rheumatoid arthritis susceptibility loci in juvenile idiopathic arthritis confirms high degree of overlap. 
  • Investigation of the PARK10 gene in Parkinson disease. 
  • Is the adiposity-associated FTO gene variant related to all-cause mortality independent of adiposity? Meta-analysis of data from 169,551 Caucasian adults. 
  • Is there protective haplotype of dysbindin gene (DTNBP1) 3 polymorphisms for major depressive disorder. 
  • Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder. 
  • Joint eQTL assessment of whole blood and dura mater tissue from individuals with Chiari type I malformation. 
  • Joint effect of multiple common SNPs predicts melanoma susceptibility. 
  • Joint effects of alcohol consumption and polymorphisms in alcohol and oxidative stress metabolism genes on risk of head and neck cancer. 
  • Joint effects of single nucleotide polymorphisms in P53BP1 and p53 on breast cancer risk in a Chinese population. 
  • Joint influence of small-effect genetic variants on human longevity. 
  • KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference. 
  • Kernel canonical correlation analysis for assessing gene-gene interactions and application to ovarian cancer. 
  • Klotho variants and chronic hemodialysis mortality. 
  • LIN28B polymorphisms influence susceptibility to epithelial ovarian cancer. 
  • LOC387715/HTRA1 and complement factor H variants in patients with age-related macular degeneration seen at the mayo clinic. 
  • LRRK2 G2019S-induced mitochondrial DNA damage is LRRK2 kinase dependent and inhibition restores mtDNA integrity in Parkinson's disease. 
  • LW protein: a promiscuous integrin receptor activated by adrenergic signaling. 
  • Lack of association between LOXL1 gene polymorphisms and primary open angle glaucoma in the Saudi Arabian population. 
  • Lack of association between LOXL1 variants and primary open-angle glaucoma in three different populations. 
  • Lack of association between UBQLN1 and Alzheimer disease. 
  • Lack of association between adrenergic receptor genotypes and survival in heart failure patients treated with carvedilol or metoprolol. 
  • Lack of association between autism and SLC25A12. 
  • Lack of association between primary angle-closure glaucoma susceptibility loci and the ocular biometric parameters anterior chamber depth and axial length. 
  • Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies. 
  • Lack of genomic imprinting of DNA primase, polypeptide 2 (PRIM2) in human term placenta and white blood cells. 
  • Lack of interaction of beta-cell-function-associated variants with hypertension on change in fasting glucose and diabetes risk: the Framingham Offspring Study. 
  • Large candidate gene association study reveals genetic risk factors and therapeutic targets for fibromyalgia. 
  • Large meta-analysis of genome-wide association studies identifies five loci for lean body mass. 
  • Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium. 
  • Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets. 
  • Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness. 
  • Large-scale association analysis identifies new risk loci for coronary artery disease. 
  • Large-scale evaluation of common variation in regulatory T cell-related genes and ovarian cancer outcome. 
  • Large-scale gene-centric analysis identifies novel variants for coronary artery disease. 
  • Large-scale genome-wide association study of coronary artery disease in genetically diverse populations. 
  • Large-scale identification and analysis of genome-wide single-nucleotide polymorphisms for mapping in Arabidopsis thaliana. 
  • Largest GWAS of PTSD (N=20 070) yields genetic overlap with schizophrenia and sex differences in heritability. 
  • Learning in glaucoma genetic risk assessment. 
  • Learning phenotype densities conditional on many interacting predictors. 
  • Lens status influences the association between CFH polymorphisms and age-related macular degeneration: findings from two population-based studies in Singapore. 
  • Letter to the editor: Standardization of genetic association studies, pros and cons, reaffirmed. 
  • Leveraging Genome and Phenome-Wide Association Studies to Investigate Genetic Risk of Acute Lymphoblastic Leukemia. 
  • Life, diversity and the pursuit of haplotypes. 
  • Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects. 
  • LigAmp for sensitive detection of single-nucleotide differences. 
  • Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters. 
  • Linkage analysis of schizophrenia in African-American families. 
  • Linkage and association studies of discoidin domain receptor 1 (DDR1) single nucleotide polymorphisms (SNPs) in juvenile oligoarthritis. 
  • Linkage and association studies of single-nucleotide polymorphism-tagged tumor necrosis factor haplotypes in juvenile oligoarthritis. 
  • Linkage and association with the NOS2A locus on chromosome 17q11 in multiple sclerosis. 
  • Linkage disequilibrium and haplotype tagging polymorphisms in the Tau H1 haplotype. 
  • Linkage disequilibrium and signatures of positive selection around LINE-1 retrotransposons in the human genome. 
  • Linkage disequilibrium at the Angelman syndrome gene UBE3A in autism families. 
  • Linking short tandem repeat polymorphisms with cytosine modifications in human lymphoblastoid cell lines. 
  • Lipoprotein receptor-related protein 1 variants and dietary fatty acids: meta-analysis of European origin and African American studies. 
  • Localized variation in ancestral admixture identifies pilocytic astrocytoma risk loci among Latino children. 
  • Long contiguous stretches of homozygosity in the human genome. 
  • Longer genotypically-estimated leukocyte telomere length is associated with increased adult glioma risk. 
  • Longer genotypically-estimated leukocyte telomere length is associated with increased meningioma risk. 
  • Longevity-Associated FOXO3 Genotype and its Impact on Coronary Artery Disease Mortality in Japanese, Whites, and Blacks: A Prospective Study of Three American Populations. 
  • Longitudinal RNA-Seq Analysis of the Repeatability of Gene Expression and Splicing in Human Platelets Identifies a Platelet SELP Splice QTL. 
  • Longitudinal evaluation of an N-ethyl-N-nitrosourea-created murine model with normal pressure hydrocephalus. 
  • Longitudinal molecular trajectories of diffuse glioma in adults. 
  • Looking beyond the exome: a phenotype-first approach to molecular diagnostic resolution in rare and undiagnosed diseases. 
  • Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions. 
  • Loss of PTPRM associates with the pathogenic development of colorectal adenoma-carcinoma sequence. 
  • Loss of TLR3 aggravates CHIKV replication and pathology due to an altered virus-specific neutralizing antibody response. 
  • Loss of the mismatched human leukocyte antigen haplotype in two acute myelogenous leukemia relapses after haploidentical bone marrow transplantation with post-transplantation cyclophosphamide. 
  • Loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression. 
  • Lost in translation? IL28B's discovery and the journey back to the patient. 
  • Low enzymatic activity haplotypes of the human catechol-O-methyltransferase gene: enrichment for marker SNPs. 
  • Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility. 
  • Lower serum hepcidin and greater parenchymal iron in nonalcoholic fatty liver disease patients with C282Y HFE mutations. 
  • Lumican and muscarinic acetylcholine receptor 1 gene polymorphisms associated with high myopia. 
  • MAPT rs242557 variant is associated with hippocampus tau uptake on 18F-AV-1451 PET in non-demented elders. 
  • MDM4 genetic variants and risk of gastric cancer in an Eastern Chinese population. 
  • MMP20 and ARMS2/HTRA1 Are Associated with Neovascular Lesion Size in Age-Related Macular Degeneration. 
  • MRE11-deficiency associated with improved long-term disease free survival and overall survival in a subset of stage III colon cancer patients in randomized CALGB 89803 trial. 
  • MYH9 and APOL1 are both associated with sickle cell disease nephropathy. 
  • Malaria severity and human nitric oxide synthase type 2 (NOS2) promoter haplotypes. 
  • Manifestations of Alzheimer's disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90. 
  • Mapping eQTL by leveraging multiple tissues and DNA methylation. 
  • Mapping genomic loci implicates genes and synaptic biology in schizophrenia. 
  • Mapping human genetic diversity in Asia. 
  • Mapping of psoriasis to 17q terminus. 
  • Mapping of the IRF8 gene identifies a 3'UTR variant associated with risk of chronic lymphocytic leukemia but not other common non-Hodgkin lymphoma subtypes. 
  • Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments. 
  • Massively parallel sequencing of patients with intellectual disability, congenital anomalies and/or autism spectrum disorders with a targeted gene panel. 
  • Maternal lineages and Alzheimer disease risk in the Old Order Amish. 
  • Maternal vitamin D receptor genetic variation contributes to infant birthweight among black mothers. 
  • Mathematical modeling of cell metabolism 
  • Matrix metalloproteinase-9 genetic polymorphisms and the risk for advanced pelvic organ prolapse. 
  • Matroshka and ectopic polymorphisms: Two new classes of DNA sequence variation identified at the Van der Woude syndrome locus on 1q32-q41. 
  • Measures of linkage disequilibrium among neighbouring SNPs indicate asymmetries across the house mouse hybrid zone. 
  • Mechanisms of dexamethasone-induced disturbed sleep and fatigue in paediatric patients receiving treatment for ALL. 
  • Meiotic chromosome segregation in triploid strains of Saccharomyces cerevisiae. 
  • Melanoma Expression Genes Identified through Genome-Wide Association Study of Breslow Tumor Thickness. 
  • Mendelian randomisation study of the relationship between vitamin D and risk of glioma. 
  • Mendelian randomization study of adiposity-related traits and risk of breast, ovarian, prostate, lung and colorectal cancer. 
  • Menthol preference among smokers: association with TRPA1 variants. 
  • Merging pharmacometabolomics with pharmacogenomics using '1000 Genomes' single-nucleotide polymorphism imputation: selective serotonin reuptake inhibitor response pharmacogenomics. 
  • Meta-Analysis of Genome-Wide Association Studies Identifies Genetic Risk Factors for Stroke in African Americans. 
  • Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci. 
  • Meta-analysis identifies common variants associated with body mass index in east Asians. 
  • Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. 
  • Meta-analysis identifies six new susceptibility loci for atrial fibrillation. 
  • Meta-analysis investigating associations between healthy diet and fasting glucose and insulin levels and modification by loci associated with glucose homeostasis in data from 15 cohorts. 
  • Meta-analysis of 2040 sickle cell anemia patients: BCL11A and HBS1L-MYB are the major modifiers of HbF in African Americans. 
  • Meta-analysis of correlated traits via summary statistics from GWASs with an application in hypertension. 
  • Meta-analysis of gene-environment interaction: joint estimation of SNP and SNP × environment regression coefficients. 
  • Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error. 
  • Meta-analysis of genome-wide association studies discovers multiple loci for chronic lymphocytic leukemia. 
  • Meta-analysis of genome-wide association studies for circulating phylloquinone concentrations. 
  • Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians. 
  • Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. 
  • Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process. 
  • Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations. 
  • Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes. 
  • Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index. 
  • Meta-analysis of genome-wide association studies in five cohorts reveals common variants in RBFOX1, a regulator of tissue-specific splicing, associated with refractive error. 
  • Meta-analysis of genome-wide association studies of HDL cholesterol response to statins. 
  • Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci. 
  • Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. 
  • Metabolomic Quantitative Trait Loci (mQTL) Mapping Implicates the Ubiquitin Proteasome System in Cardiovascular Disease Pathogenesis. 
  • Metabolomic and genetic associations with insulin resistance in pregnancy. 
  • Metachronous/concomitant B-cell neoplasms with discordant light-chain or heavy-chain isotype restrictions: evidence of distinct B-cell neoplasms rather than clonal evolutions. 
  • Methadone Pharmacogenetics: CYP2B6 Polymorphisms Determine Plasma Concentrations, Clearance, and Metabolism. 
  • Methodological remarks concerning the recent meta-analysis on p53 codon 72 polymorphism and colorectal cancer risk. 
  • Methyl-CpG binding domain 1 gene polymorphisms and lung cancer risk in a Chinese population. 
  • Methylomics of gene expression in human monocytes. 
  • MicroRNA binding-site polymorphisms as potential biomarkers of cancer risk. 
  • MicroRNA processing and binding site polymorphisms are not replicated in the Ovarian Cancer Association Consortium. 
  • MicroRNA variants increase the risk of HPV-associated squamous cell carcinoma of the oropharynx in never smokers. 
  • Microbially driven TLR5-dependent signaling governs distal malignant progression through tumor-promoting inflammation. 
  • Mitochondrial DNA polymorphism A4917G is independently associated with age-related macular degeneration. 
  • Mitochondrial Genome Variation Affects Multiple Respiration and Nonrespiration Phenotypes in Saccharomyces cerevisiae. 
  • Mitochondrial polymorphism A10398G and Haplogroup I are associated with Fuchs' endothelial corneal dystrophy. 
  • Mitochondrial polymorphisms significantly reduce the risk of Parkinson disease. 
  • Modeling of variables in cellular infection reveals CXCL10 levels are regulated by human genetic variation and the Chlamydia-encoded CPAF protease. 
  • Modeling the probability of sustained virological response to therapy with pegylated interferon plus ribavirin in patients coinfected with hepatitis C virus and HIV. 
  • Modification of COMT-dependent pain sensitivity by psychological stress and sex. 
  • Modifying effect of mouse double minute-2 promoter variants on risk of recurrence for patients with squamous cell carcinoma of oropharynx. 
  • Modulation of the BP response to diet by genes in the renin-angiotensin system and the adrenergic nervous system. 
  • Module-based association analysis for omics data with network structure. 
  • Molecular characterization of the pediatric preclinical testing panel. 
  • Molecular genetics of nicotine dependence and abstinence: whole genome association using 520,000 SNPs. 
  • Molecular genetics of successful smoking cessation: convergent genome-wide association study results. 
  • Monoacylglycerol lipase (MGLL) polymorphism rs604300 interacts with childhood adversity to predict cannabis dependence symptoms and amygdala habituation: Evidence from an endocannabinoid system-level analysis. 
  • Mouse double minute 4 variants modify susceptibility to risk of recurrence in patients with squamous cell carcinoma of the oropharynx. 
  • Mouse model of OPRM1 (A118G) polymorphism has altered hippocampal function. 
  • Mouse model of OPRM1 (A118G) polymorphism has sex-specific effects on drug-mediated behavior. 
  • Multi-Trait Analysis of GWAS and Biological Insights Into Cognition: A Response to Hill (2018). 
  • Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation. 
  • Multi-ancestry genome- and phenome-wide association studies of diverticular disease in electronic health records with natural language processing enriched phenotyping algorithm. 
  • Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure. 
  • Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration. 
  • Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing. 
  • Multi-ethnic GWAS and meta-analysis of sleep quality identify MPP6 as a novel gene that functions in sleep center neurons. 
  • Multi-trait association studies discover pleiotropic loci between Alzheimer's disease and cardiometabolic traits. 
  • Multi-trait genome-wide association study identifies new loci associated with optic disc parameters. 
  • Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. 
  • Multicentre search for genetic susceptibility loci in sporadic epilepsy syndrome and seizure types: a case-control study. 
  • Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control. 
  • Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. 
  • Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function. 
  • Multiethnic polygenic risk scores improve risk prediction in diverse populations. 
  • Multifactor dimensionality reduction reveals gene-gene interactions associated with multiple sclerosis susceptibility in African Americans. 
  • Multifocal anaplastic astrocytoma in a patient with hereditary colorectal cancer, transcobalamin II deficiency, agenesis of the corpus callosum, mental retardation, and inherited PMS2 mutation. 
  • Multiple distinct clones may co-exist in different lineages in myelodysplastic syndromes. 
  • Multiple genetic variants explain measurable variance in type 2 diabetes-related traits in Pakistanis. 
  • Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer. 
  • Multiple loci are associated with white blood cell phenotypes. 
  • Multiple mutations and mutation combinations in the sodium channel of permethrin resistant mosquitoes, Culex quinquefasciatus. 
  • Multiple nonglycemic genomic loci are newly associated with blood level of glycated hemoglobin in East Asians. 
  • Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma. 
  • Multiple regions within 8q24 independently affect risk for prostate cancer. 
  • Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility. 
  • Mutational signatures of de-differentiation in functional non-coding regions of melanoma genomes. 
  • Mutational spectrum of the ZEB1 gene in corneal dystrophies supports a genotype-phenotype correlation. 
  • Mutations in WDR62, encoding a centrosome-associated protein, cause microcephaly with simplified gyri and abnormal cortical architecture. 
  • Mutations in sphingolipid metabolism genes are associated with ADHD. 
  • Myocilin polymorphisms and high myopia in subjects of European origin. 
  • Myotilin is not the causative gene for vocal cord and pharyngeal weakness with distal myopathy (VCPDM). 
  • NCAM1 and neurocognition in schizophrenia. 
  • NF1 inactivation in adult acute myelogenous leukemia. 
  • NOS2A and the modulating effect of cigarette smoking in Parkinson's disease. 
  • NOS2A, TLR4, and IFNGR1 interactions influence pulmonary tuberculosis susceptibility in African-Americans. 
  • National Cancer Institute Prostate Cancer Genetics Workshop. 
  • Natural History of Drusenoid Pigment Epithelial Detachment Associated with Age-Related Macular Degeneration: Age-Related Eye Disease Study 2 Report No. 17. 
  • Natural allelic variation of the IL-21 receptor modulates ischemic stroke infarct volume. 
  • Natural genetic variants influencing type 1 diabetes in humans and in the NOD mouse. 
  • Natural genetic variation of integrin alpha L (Itgal) modulates ischemic brain injury in stroke. 
  • Natural positive selection and north-south genetic diversity in East Asia. 
  • Neonatal nonepileptic myoclonus is a prominent clinical feature of KCNQ2 gain-of-function variants R201C and R201H. 
  • Neovascular age-related macular degeneration and its association with LOC387715 and complement factor H polymorphism. 
  • Nested Inversion Polymorphisms Predispose Chromosome 22q11.2 to Meiotic Rearrangements. 
  • Network-based SNP meta-analysis identifies joint and disjoint genetic features across common human diseases. 
  • Neural mechanisms underlying 5-HTTLPR-related sensitivity to acute stress. 
  • Neural tube defects and folate pathway genes: family-based association tests of gene-gene and gene-environment interactions. 
  • Neurogenetic plasticity and sex influence the link between corticolimbic structural connectivity and trait anxiety. 
  • New genetic loci link adipose and insulin biology to body fat distribution. 
  • New loci and coding variants confer risk for age-related macular degeneration in East Asians. 
  • Newborn screening for Krabbe disease in New York State: the first eight years' experience. 
  • Next-Generation Sequencing Concordance Analysis of Comprehensive Solid Tumor Profiling between a Centralized Specialty Laboratory and the Decentralized Personal Genome Diagnostics elio Tissue Complete Kitted Solution. 
  • Next-generation computational genetic analysis: multiple complement alleles control survival after Candida albicans infection. 
  • Nicotine oxidation by genetic variants of CYP2B6 and in human brain microsomes. 
  • Nicotinic receptor gene variants interact with attention deficient hyperactive disorder symptoms to predict smoking trajectories from early adolescence to adulthood. 
  • Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error. 
  • Nitric oxide synthase 2(Lambaréné) (G-954C), increased nitric oxide production, and protection against malaria. 
  • No association between OPA1 polymorphisms and primary open-angle glaucoma in three different populations. 
  • No association between Parkinson disease alleles and the risk of melanoma. 
  • No association between TGFB1 polymorphisms and late radiotherapy toxicity: a meta-analysis. 
  • No association between the APOE gene and autism. 
  • No association of 9p21 with arterial elasticity and retinal microvascular findings. 
  • No association of the serotonin transporter polymorphisms 5-HTTLPR and RS25531 with schizophrenia or neurocognition. 
  • No evidence for maternal-fetal microchimerism in infantile hemangioma: a molecular genetic investigation. 
  • No evidence of association of heterozygous NTF4 mutations in patients with primary open-angle glaucoma. 
  • No man is an island: living in a disadvantaged neighborhood influences chronic pain development after motor vehicle collision. 
  • Non-additive and epistatic effects of HLA polymorphisms contributing to risk of adult glioma. 
  • Nonrandom distribution of interhomolog recombination events induced by breakage of a dicentric chromosome in Saccharomyces cerevisiae. 
  • Norrie disease gene sequence variants in an ethnically diverse population with retinopathy of prematurity. 
  • Novel Genetic Loci Associated With Retinal Microvascular Diameter. 
  • Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis. 
  • Novel Neuroprotective Loci Modulating Ischemic Stroke Volume in Wild-Derived Inbred Mouse Strains. 
  • Novel associations of UDP-glucuronosyltransferase 2B gene variants with prostate cancer risk in a multiethnic study. 
  • Novel childhood ALL susceptibility locus BMI1-PIP4K2A is specifically associated with the hyperdiploid subtype. 
  • Novel congenital myopathy locus identified in Native American Indians at 12q13.13-14.1. 
  • Novel exonic mu-opioid receptor gene (OPRM1) polymorphisms not associated with opioid dependence. 
  • Novel functional variants in the Notch pathway and survival of Chinese colorectal cancer. 
  • Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. 
  • Novel genetic loci associated with prostate cancer in the Japanese population. 
  • Novel genetic loci underlying human intracranial volume identified through genome-wide association. 
  • Novel genetic variants in HDAC2 and PPARGC1A of the CREB-binding protein pathway predict survival of non-small-cell lung cancer. 
  • Novel genetic variants in KIF16B and NEDD4L in the endosome-related genes are associated with nonsmall cell lung cancer survival. 
  • Novel genetic variants in the P38MAPK pathway gene ZAK and susceptibility to lung cancer. 
  • Novel human alpha1a-adrenoceptor single nucleotide polymorphisms alter receptor pharmacology and biological function. 
  • Novel loci and pathways significantly associated with longevity. 
  • Novel loci associated with PR interval in a genome-wide association study of 10 African American cohorts. 
  • Novel loci associated with usual sleep duration: the CHARGE Consortium Genome-Wide Association Study. 
  • Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. 
  • Novel susceptibility gene for nonfamilial hypokalemic periodic paralysis. 
  • Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations. 
  • Novel susceptibility variants at the ERG locus for childhood acute lymphoblastic leukemia in Hispanics. 
  • Novelty seeking and the dopamine D4 receptor gene (DRD4) revisited in Asians: haplotype characterization and relevance of the 2-repeat allele. 
  • Nucleotide excision repair core gene polymorphisms and risk of second primary malignancy in patients with index squamous cell carcinoma of the head and neck. 
  • OPRM1 SNP (A118G): involvement in disease development, treatment response, and animal models. 
  • OTX2 is critical for the maintenance and progression of Shh-independent medulloblastomas. 
  • Obesity and diabetes genetic variants associated with gestational weight gain. 
  • Obesity-related genetic variants, human pigmentation, and risk of melanoma. 
  • On the interplay of telomeres, nevi and the risk of melanoma. 
  • Open window: when easily identifiable genomes and traits are in the public domain. 
  • Ovarian cancer risk associated with inherited inflammation-related variants. 
  • Ovarian cancer risk, ALDH2 polymorphism and alcohol drinking: Asian data from the Ovarian Cancer Association Consortium. 
  • Overlapping high-resolution copy number alterations in cancer genomes identified putative cancer genes in hepatocellular carcinoma. 
  • Ovulatory response to treatment of polycystic ovary syndrome is associated with a polymorphism in the STK11 gene. 
  • PCSK9 Loss-of-Function Variants, Low-Density Lipoprotein Cholesterol, and Risk of Coronary Heart Disease and Stroke: Data From 9 Studies of Blacks and Whites. 
  • PGC-1 coactivators regulate MITF and the tanning response. 
  • PSCA polymorphisms and gastric cancer susceptibility in an eastern Chinese population. 
  • Pain modality- and sex-specific effects of COMT genetic functional variants. 
  • Pain perception is altered by a nucleotide polymorphism in SCN9A. 
  • Pain sensitivity and vasopressin analgesia are mediated by a gene-sex-environment interaction. 
  • Painful Temporomandibular Disorder: Decade of Discovery from OPPERA Studies. 
  • Pancreatic cancer: translating lessons from mouse models. 
  • Paradoxical relationship between chromosomal instability and survival outcome in cancer. 
  • Parsing the genetic heterogeneity of chromosome 12q susceptibility genes for Alzheimer disease by family-based association analysis. 
  • Partitioned glioma heritability shows subtype-specific enrichment in immune cells. 
  • Pathogenic Germline Variants in 10,389 Adult Cancers. 
  • Pathway discovery in mantle cell lymphoma by integrated analysis of high-resolution gene expression and copy number profiling. 
  • Pathway-analysis of published genome-wide association studies of lung cancer: A potential role for the CYP4F3 locus. 
  • Pathway-based identification of SNPs predictive of survival. 
  • Pathways-driven sparse regression identifies pathways and genes associated with high-density lipoprotein cholesterol in two Asian cohorts. 
  • Pattern Discovery in Brain Imaging Genetics via SCCA Modeling with a Generic Non-convex Penalty. 
  • Peakwide mapping on chromosome 3q13 identifies the kalirin gene as a novel candidate gene for coronary artery disease. 
  • Pediatric cataract, myopic astigmatism, familial exudative vitreoretinopathy and primary open-angle glaucoma co-segregating in a family. 
  • Penalized multimarker vs. single-marker regression methods for genome-wide association studies of quantitative traits. 
  • Performance of Three Inherited Risk Measures for Predicting Prostate Cancer Incidence and Mortality: A Population-based Prospective Analysis. 
  • Peripheral reticular pigmentary change is associated with complement factor H polymorphism (Y402H) in age-related macular degeneration. 
  • Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. 
  • PharmGKB summary: peginterferon-α pathway. 
  • Pharmacogenetic Discovery in CALGB (Alliance) 90401 and Mechanistic Validation of a VAC14 Polymorphism that Increases Risk of Docetaxel-Induced Neuropathy. 
  • Pharmacogenetic analysis of genes implicated in rodent models of antidepressant response: association of TREK1 and treatment resistance in the STAR(*)D study. 
  • Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins. 
  • Pharmacogenetic predictors of statin-mediated low-density lipoprotein cholesterol reduction and dose response. 
  • Pharmacogenetics goes 3D. 
  • Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis. 
  • Pharmacogenetics studies in STAR*D: strengths, limitations, and results. 
  • Pharmacogenomic polygenic response score predicts ischaemic events and cardiovascular mortality in clopidogrel-treated patients. 
  • Pharmacogenomics and end-organ susceptibility to injury in the perioperative period. 
  • Pharmacogenomics study of thiazide diuretics and QT interval in multi-ethnic populations: the cohorts for heart and aging research in genomic epidemiology. 
  • Pharmacogenomics-Driven Prediction of Antidepressant Treatment Outcomes: A Machine-Learning Approach With Multi-trial Replication. 
  • Pharmacokinetic interactions and safety evaluations of coadministered tafenoquine and chloroquine in healthy subjects. 
  • Pharmacometabolomics reveals racial differences in response to atenolol treatment. 
  • PheProb: probabilistic phenotyping using diagnosis codes to improve power for genetic association studies. 
  • Phenome-wide association studies (PheWASs) for functional variants. 
  • Phenotype analysis of patients with the risk variant LOC387715 (A69S) in age-related macular degeneration. 
  • Phenotypic definition of Chiari type I malformation coupled with high-density SNP genome screen shows significant evidence for linkage to regions on chromosomes 9 and 15. 
  • Plasma Levels of Soluble Interleukin-2 Receptor α: Associations With Clinical Cardiovascular Events and Genome-Wide Association Scan. 
  • Plasmonic coupling interference (PCI) nanoprobes for nucleic acid detection. 
  • Plasmonics nanoprobes: detection of single-nucleotide polymorphisms in the breast cancer BRCA1 gene. 
  • Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways. 
  • Pleiotropic predisposition to Alzheimer's disease and educational attainment: insights from the summary statistics analysis. 
  • Pleiotropy among common genetic loci identified for cardiometabolic disorders and C-reactive protein. 
  • Pleiotropy and allelic heterogeneity in the TOMM40-APOE genomic region related to clinical and metabolic features of hepatitis C infection. 
  • Polygenic Score for β-Blocker Survival Benefit in European Ancestry Patients With Reduced Ejection Fraction Heart Failure. 
  • Polygenic effects of common single-nucleotide polymorphisms on life span: when association meets causality. 
  • Polygenic inheritance of paclitaxel-induced sensory peripheral neuropathy driven by axon outgrowth gene sets in CALGB 40101 (Alliance). 
  • Polygenic model of DNA repair genetic polymorphisms in human breast cancer risk. 
  • Polygenic risk for schizophrenia and measured domains of cognition in individuals with psychosis and controls. 
  • Polygenic risk modeling for prediction of epithelial ovarian cancer risk. 
  • Polygenic risk score for disability and insights into disability-related molecular mechanisms. 
  • Polymorphic TP53BP1 and TP53 gene interactions associated with risk of squamous cell carcinoma of the head and neck. 
  • Polymorphic variants in tenascin-C (TNC) are associated with atherosclerosis and coronary artery disease. 
  • Polymorphism in the GALNT1 gene and epithelial ovarian cancer in non-Hispanic white women: the Ovarian Cancer Association Consortium. 
  • Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women. 
  • Polymorphism in the TOMM40 gene modifies the risk of developing sporadic inclusion body myositis and the age of onset of symptoms. 
  • Polymorphisms and haplotypes of serine hydroxymethyltransferase and risk of squamous cell carcinoma of the head and neck: a case-control analysis. 
  • Polymorphisms associated with in vitro aspirin resistance are not associated with clinical outcomes in patients with coronary artery disease who report regular aspirin use. 
  • Polymorphisms at newly identified lipid-associated loci are associated with blood lipids and cardiovascular disease in an Asian Malay population. 
  • Polymorphisms at the microRNA binding-site of the stem cell marker gene CD133 modify susceptibility to and survival of gastric cancer. 
  • Polymorphisms identified through genome-wide association studies and their associations with type 2 diabetes in Chinese, Malays, and Asian-Indians in Singapore. 
  • Polymorphisms in DNA damage binding protein 2 (DDB2) and susceptibility of primary lung cancer in the Chinese: a case-control study. 
  • Polymorphisms in ERCC1 and XPF genes and risk of gastric cancer in an eastern Chinese population. 
  • Polymorphisms in Fibronectin Binding Proteins A and B among Staphylococcus aureus Bloodstream Isolates Are Not Associated with Arthroplasty Infection. 
  • Polymorphisms in MicroRNAs are associated with survival in non-small cell lung cancer. 
  • Polymorphisms in NAT2 and GSTP1 are associated with survival in oral and oropharyngeal cancer. 
  • Polymorphisms in NF-kappaB inhibitors and risk of epithelial ovarian cancer. 
  • Polymorphisms in TCEAL7 and risk of epithelial ovarian cancer. 
  • Polymorphisms in excision repair cross-complementing group 4 (ERCC4) and susceptibility to primary lung cancer in a Chinese Han population. 
  • Polymorphisms in mTORC1 genes modulate risk of esophageal squamous cell carcinoma in eastern Chinese populations. 
  • Polymorphisms in microRNA targets: a gold mine for molecular epidemiology. 
  • Polymorphisms in nucleotide excision repair genes and risk of primary prostate cancer in Chinese Han populations. 
  • Polymorphisms in stromal genes and susceptibility to serous epithelial ovarian cancer: a report from the Ovarian Cancer Association Consortium. 
  • Polymorphisms in the ACE and ADRB2 genes and risks of aging-associated phenotypes: the case of myocardial infarction. 
  • Polymorphisms in the AKT1 and AKT2 genes and oesophageal squamous cell carcinoma risk in an Eastern Chinese population. 
  • Polymorphisms in the ERCC5 gene and risk of esophageal squamous cell carcinoma (ESCC) in Eastern Chinese populations. 
  • Polymorphisms in the MDM2 promoter and risk of breast cancer: a case-control analysis in a Chinese population. 
  • Polymorphisms in the PON gene cluster are associated with Alzheimer disease. 
  • Polymorphisms in the SULF1 gene are associated with early age of onset and survival of ovarian cancer. 
  • Polymorphisms in the XPG gene and risk of gastric cancer in Chinese populations. 
  • Polymorphisms in the glucocorticoid receptor co-chaperone FKBP5 predict persistent musculoskeletal pain after traumatic stress exposure. 
  • Polymorphisms in the kinesin-like factor 1 B gene and risk of epithelial ovarian cancer in Eastern Chinese women. 
  • Polymorphisms in the mTOR gene and risk of sporadic prostate cancer in an Eastern Chinese population. 
  • Polymorphisms in the prostate-specific antigen gene promoter do not predict serum prostate-specific antigen levels in African-American men. 
  • Polymorphisms in the two helicases ERCC2/XPD and ERCC3/XPB of the transcription factor IIH complex and risk of lung cancer: a case-control analysis in a Chinese population. 
  • Polymorphisms of CAK genes and risk for lung cancer: a case-control study in Chinese population. 
  • Polymorphisms of LIG4 and XRCC4 involved in the NHEJ pathway interact to modify risk of glioma. 
  • Polymorphisms of MDM4 and risk of squamous cell carcinoma of the head and neck. 
  • Polymorphisms of TP53 Arg72Pro, but not p73 G4C14>A4TA4 and p21 Ser31Arg, contribute to risk of cutaneous melanoma. 
  • Polymorphisms of homologous recombination genes and clinical outcomes of non-small cell lung cancer patients treated with definitive radiotherapy. 
  • Polymorphisms of methionine synthase and methionine synthase reductase and risk of lung cancer: a case-control analysis. 
  • Polymorphisms of nucleotide excision repair genes predict melanoma survival. 
  • Polymorphisms of p16, p27, p73, and MDM2 modulate response and survival of pancreatic cancer patients treated with preoperative chemoradiation. 
  • Polymorphisms of p21 and p27 jointly contribute to an earlier age at diagnosis of pancreatic cancer. 
  • Polymorphisms of the DNA repair gene MGMT and risk and progression of head and neck cancer. 
  • Polymorphisms of the DNMT3B gene and risk of squamous cell carcinoma of the head and neck: a case-control study. 
  • Polymorphisms of the HDL receptor gene associated with HDL cholesterol levels in diabetic kindred from three populations. 
  • Polymorphisms of the Interleukin 6 gene contribute to cervical cancer susceptibility in Eastern Chinese women. 
  • Polymorphisms of the centrosomal gene (FGFR1OP) and lung cancer risk: a meta-analysis of 14,463 cases and 44,188 controls. 
  • Polymorphisms of the neuronal and inducible nitric oxide synthase genes and the risk of cutaneous melanoma: a case-control study. 
  • Polymorphisms of the scavenger receptor class B member 1 are associated with insulin resistance with evidence of gene by sex interaction. 
  • Polymorphisms of the tumor suppressor gene LSAMP are associated with left main coronary artery disease. 
  • Polymorphisms of the vascular endothelial growth factor gene and severe radiation pneumonitis in non-small cell lung cancer patients treated with definitive radiotherapy. 
  • Population Pharmacokinetics/Pharmacodynamics of 3,4-Diaminopyridine Free Base in Patients With Lambert-Eaton Myasthenia. 
  • Population history in Arabidopsis halleri using multilocus analysis. 
  • Positive association of SLC26A2 gene polymorphisms with susceptibility to systemic-onset juvenile idiopathic arthritis. 
  • Positive selection on a human-specific transcription factor binding site regulating IL4 expression. 
  • Possible association between genetic variants in the H2AFX promoter region and risk of adult glioma in a Chinese Han population. 
  • Potential functional variants in SMC2 and TP53 in the AURORA pathway genes and risk of pancreatic cancer. 
  • Potentially Functional Variants of ATG16L2 Predict Radiation Pneumonitis and Outcomes in Patients with Non-Small Cell Lung Cancer after Definitive Radiotherapy. 
  • Potentially functional genetic variants in PLIN2, SULT2A1 and UGT1A9 genes of the ketone pathway and survival of nonsmall cell lung cancer. 
  • Potentially functional genetic variants in the TNF/TNFR signaling pathway genes predict survival of patients with non-small cell lung cancer in the PLCO cancer screening trial. 
  • Potentially functional genetic variants in the complement-related immunity gene-set are associated with non-small cell lung cancer survival. 
  • Potentially functional genetic variants of VAV2 and PSMA4 in the immune-activation pathway and non-small cell lung cancer survival. 
  • Potentially functional polymorphisms in the CASP7 gene contribute to gastric adenocarcinoma susceptibility in an eastern Chinese population. 
  • Potentially functional polymorphisms in the ERCC2 gene and risk of esophageal squamous cell carcinoma in Chinese populations. 
  • Potentially functional polymorphisms of EXO1 and risk of lung cancer in a Chinese population: A case-control analysis. 
  • Potentially functional single nucleotide polymorphisms in the core nucleotide excision repair genes and risk of squamous cell carcinoma of the head and neck. 
  • Potentially functional variants in nucleotide excision repair pathway genes predict platinum treatment response of Chinese ovarian cancer patients. 
  • Potentially functional variants in the core nucleotide excision repair genes predict survival in Japanese gastric cancer patients. 
  • Potentially functional variants of ERAP1, PSMF1 and NCF2 in the MHC-I-related pathway predict non-small cell lung cancer survival. 
  • Potentially functional variants of HBEGF and ITPR3 in GnRH signaling pathway genes predict survival of non-small cell lung cancer patients. 
  • Potentially functional variants of PLCE1 identified by GWASs contribute to gastric adenocarcinoma susceptibility in an eastern Chinese population. 
  • Power and sample size calculations for SNP association studies with censored time-to-event outcomes. 
  • Pre-miRNA variants as predictors of clinical outcome in patients with squamous cell carcinomas of the nonoropharynx. 
  • Pre-microRNA variants predict HPV16-positive tumors and survival in patients with squamous cell carcinoma of the oropharynx. 
  • Preanalytical Variables for the Genomic Assessment of the Cellular and Acellular Fractions of the Liquid Biopsy in a Cohort of Breast Cancer Patients. 
  • Predicting Alzheimer's Disease Using Combined Imaging-Whole Genome SNP Data. 
  • Predicting HLA genotypes using unphased and flanking single-nucleotide polymorphisms in Han Chinese population. 
  • Predicting toxicity from radiation therapy--it's genetic, right? 
  • Prediction of a time-to-event trait using genome wide SNP data. 
  • Predictors of Outcome in Ulcerative Colitis. 
  • Preface to the special issue: ecological and evolutionary genomics of populations in nature. 
  • Preliminary examination of polymorphisms of GSTM1, GSTT1, and GSTZ1 in relation to semen quality. 
  • Pri-miR-124 rs531564 and pri-miR-34b/c rs4938723 polymorphisms are associated with decreased risk of esophageal squamous cell carcinoma in Chinese populations. 
  • Primer-BLAST: a tool to design target-specific primers for polymerase chain reaction. 
  • PrimerZ: streamlined primer design for promoters, exons and human SNPs. 
  • Probing the role of PPARγ in the regulation of late-onset Alzheimer's disease-associated genes. 
  • Progesterone receptor gene polymorphisms and risk of endometriosis: results from an international collaborative effort. 
  • Progesterone receptor variation and risk of ovarian cancer is limited to the invasive endometrioid subtype: results from the Ovarian Cancer Association Consortium pooled analysis. 
  • Promoter polymorphisms in matrix metallopeptidase 1 and risk of cutaneous melanoma. 
  • Prospective associations of coronary heart disease loci in African Americans using the MetaboChip: the PAGE study. 
  • Prostate Cancer Predisposition. 
  • Prostate cancer in African American men. 
  • Prostate cancer susceptibility polymorphism rs2660753 is not associated with invasive ovarian cancer. 
  • Prostatic alpha-linolenic acid (ALA) is positively associated with aggressive prostate cancer: a relationship which may depend on genetic variation in ALA metabolism. 
  • Protective effect of CRHR1 gene variants on the development of adult depression following childhood maltreatment: replication and extension. 
  • Protective effect of complement factor B and complement component 2 variants in age-related macular degeneration. 
  • Protein prediction for trait mapping in diverse populations. 
  • Putative functional polymorphisms of MMP9 predict survival of NSCLC in a Chinese population. 
  • Putatively functional PLCE1 variants and susceptibility to esophageal squamous cell carcinoma (ESCC): a case-control study in eastern Chinese populations. 
  • QTL Mapping in Three Rice Populations Uncovers Major Genomic Regions Associated with African Rice Gall Midge Resistance. 
  • Quantitative genetic analysis of the retinal vascular caliber: the Australian Twins Eye Study. 
  • RAD52 variants predict platinum resistance and prognosis of cervical cancer. 
  • REV3L 3'UTR 460 T>C polymorphism in microRNA target sites contributes to lung cancer susceptibility. 
  • RSPO3 impacts body fat distribution and regulates adipose cell biology in vitro. 
  • Race, common genetic variation, and therapeutic response disparities in heart failure. 
  • Radiation response genotype and risk of differentiated thyroid cancer: a case-control analysis. 
  • Radiographic severity of knee osteoarthritis is conditional on interleukin 1 receptor antagonist gene variations. 
  • Random Forests approach for identifying additive and epistatic single nucleotide polymorphisms associated with residual feed intake in dairy cattle. 
  • Random forests for genetic association studies. 
  • Randomized trial of personal genomics for preventive cardiology: design and challenges. 
  • Rapid and sensitive method for detection of Y402, H402, I62, and V62 variants of complement factor H in human plasma samples using mass spectrometry. 
  • Rapid detection of submicroscopic chromosomal rearrangements in children with multiple congenital anomalies using high density oligonucleotide arrays. 
  • Rare BRCA1 haplotypes including 3'UTR SNPs associated with breast cancer risk. 
  • Rare and de novo coding variants in chromodomain genes in Chiari I malformation. 
  • Rare and low-frequency exonic variants and gene-by-smoking interactions in pulmonary function. 
  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. 
  • Rare genetic variants correlate with better processing speed. 
  • Rare genetic variants explain missing heritability in smoking. 
  • Reciprocal uniparental disomy in yeast. 
  • Red blood cell folate concentrations and polyglutamate distribution in juvenile arthritis: predictors of folate variability. 
  • Regulation of alpha-synuclein expression: implications for Parkinson's disease. 
  • Regulation of hetDNA Length during Mitotic Double-Strand Break Repair in Yeast. 
  • Regulator of G-protein signaling (RGS) proteins in cancer biology. 
  • Regulatory network motifs and hotspots of cancer genes in a mammalian cellular signalling network. 
  • Relation of age-related cataract with obesity and obesity genes in an Asian population. 
  • Religiosity and Telomere Length: Moderating Effect of Religiosity on the Relationship Between High-Risk Polymorphisms of the Apolipoprotein E and TOMM40 Gene and Telomere Length. 
  • Remarkably little variation in proteins encoded by the Y chromosome's single-copy genes, implying effective purifying selection. 
  • Replication and meta-analysis of GWAS identified susceptibility loci in Kawasaki disease confirm the importance of B lymphoid tyrosine kinase (BLK) in disease susceptibility. 
  • Replication in Imaging Genetics: The Case of Threat-Related Amygdala Reactivity. 
  • Replication of 13 obesity loci among Singaporean Chinese, Malay and Asian-Indian populations. 
  • Replication of TCF4 through association and linkage studies in late-onset Fuchs endothelial corneal dystrophy. 
  • Replication of breast cancer susceptibility loci in whites and African Americans using a Bayesian approach. 
  • Replication of genome-wide association signals of type 2 diabetes in Han Chinese in a prospective cohort. 
  • Report and abstracts of the sixth international workshop on human chromosome 1 mapping 2000. Iowa City, Iowa, USA. 30 September-3 October 2000. 
  • Resource profile and user guide of the Polygenic Index Repository. 
  • Results of a pilot multicenter genotype-based randomized placebo-controlled trial of propranolol to reduce pain after major thermal burn injury. 
  • Revealing the role of glutathione S-transferase omega in age-at-onset of Alzheimer and Parkinson diseases. 
  • Reward-related ventral striatum reactivity mediates gender-specific effects of a galanin remote enhancer haplotype on problem drinking. 
  • Risk Prediction for Epithelial Ovarian Cancer in 11 United States-Based Case-Control Studies: Incorporation of Epidemiologic Risk Factors and 17 Confirmed Genetic Loci. 
  • Risk alleles for multiple sclerosis identified by a genomewide study. 
  • Risk factors for breast cancer characterized by the estrogen receptor alpha A908G (K303R) mutation. 
  • Risk of ovarian cancer and inherited variants in relapse-associated genes. 
  • Risk of ovarian cancer and the NF-κB pathway: genetic association with IL1A and TNFSF10. 
  • Robust analysis of secondary phenotypes in case-control genetic association studies. 
  • Role of GABRA2 in trajectories of externalizing behavior across development and evidence of moderation by parental monitoring. 
  • Role of autophagy genetic variants for the risk of Candida infections. 
  • Role of common genetic variants in ovarian cancer susceptibility and outcome: progress to date from the Ovarian Cancer Association Consortium (OCAC). 
  • Role of monoamine-oxidase-A-gene variation in the development of glioblastoma in males: a case control study. 
  • Role of β-3 adrenergic receptor polymorphism in overactive bladder. 
  • Roles of genetic variants in the PI3K and RAS/RAF pathways in susceptibility to endometrial cancer and clinical outcomes. 
  • SAQC: SNP array quality control. 
  • SLC1A2 variant associated with essential tremor but not Parkinson disease in Chinese subjects. 
  • SLC2A10 genetic polymorphism predicts development of peripheral arterial disease in patients with type 2 diabetes. SLC2A10 and PAD in type 2 diabetes. 
  • SLC6A4 variation and citalopram response. 
  • SLCO1B1*5 Allele Is Associated With Atorvastatin Discontinuation and Adverse Muscle Symptoms in the Context of Routine Care. 
  • SLITRK1 mutations in trichotillomania. 
  • SMRT Sequencing for Parallel Analysis of Multiple Targets and Accurate SNP Phasing. 
  • SNP array-based analyses of unbalanced embryos as a reference to distinguish between balanced translocation carrier and normal blastocysts. 
  • SNP selection in genome-wide association studies via penalized support vector machine with MAX test. 
  • SNP-skimming: A fast approach to map loci generating quantitative variation in natural populations. 
  • SNPing away at complex diseases: analysis of single-nucleotide polymorphisms around APOE in Alzheimer disease. 
  • SNPpy--database management for SNP data from genome wide association studies. 
  • SNPs in CAST are associated with Parkinson disease: a confirmation study. 
  • SNPs in Multi-species Conserved Sequences (MCS) as useful markers in association studies: a practical approach. 
  • SNPs in dopamine D2 receptor gene (DRD2) and norepinephrine transporter gene (NET) are associated with continuous performance task (CPT) phenotypes in ADHD children and their families. 
  • SNPs in the neural cell adhesion molecule 1 gene (NCAM1) may be associated with human neural tube defects. 
  • SNPselector: a web tool for selecting SNPs for genetic association studies. 
  • SOD2 polymorphisms: unmasking the effect of polymorphism on splicing. 
  • Screening for familial and hereditary prostate cancer. 
  • Screening the human exome: a comparison of whole genome and whole transcriptome sequencing. 
  • Selected polymorphisms of DNA repair genes and risk of pancreatic cancer. 
  • Semi-supervised validation of multiple surrogate outcomes with application to electronic medical records phenotyping. 
  • Sensitive DNA detection and SNP discrimination using ultrabright SERS nanorattles and magnetic beads for malaria diagnostics. 
  • Separating the mechanism-based and off-target actions of cholesteryl ester transfer protein inhibitors with CETP gene polymorphisms. 
  • Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction. 
  • Sequence variation in alpha-methylacyl-CoA racemase and risk of early-onset and familial prostate cancer. 
  • Sequence variation in the mitochondrial gene cytochrome c oxidase subunit I and prostate cancer in African American men. 
  • Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program. 
  • Serious pulmonary toxicity in patients with Hodgkin's lymphoma with SGN-30, gemcitabine, vinorelbine, and liposomal doxorubicin is associated with an FcγRIIIa-158 V/F polymorphism. 
  • Serotonin transporter gene polymorphisms and brain function during emotional distraction from cognitive processing in posttraumatic stress disorder. 
  • Serotonin transporter-linked polymorphic region (5-HTTLPR) genotype and stressful life events interact to predict preschool-onset depression: a replication and developmental extension. 
  • Serum magnesium and calcium levels in relation to ischemic stroke: Mendelian randomization study. 
  • Seven new loci associated with age-related macular degeneration. 
  • Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study. 
  • Seven-Year Follow-Up Analysis of Adjuvant Paclitaxel and Trastuzumab Trial for Node-Negative, Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer. 
  • Severe Salt-Losing 3β-Hydroxysteroid Dehydrogenase Deficiency: Treatment and Outcomes of HSD3B2 c.35G>A Homozygotes. 
  • Severe childhood asthma exacerbations: Is treatment response variability in the genes? 
  • Sex Differences in Genetic Associations With Longevity. 
  • Sex and Menopause Modify the Effect of Single Nucleotide Polymorphism Genotypes on Fibrosis in NAFLD. 
  • Sex- and age-specific genetic analysis of chronic back pain. 
  • Sex-Based Genetic Association Study Identifies CELSR1 as a Possible Chronic Obstructive Pulmonary Disease Risk Locus among Women. 
  • Sex-Specific Genetic Associations for Barrett's Esophagus and Esophageal Adenocarcinoma. 
  • Sex-specific gene and pathway modeling of inherited glioma risk. 
  • Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21. 
  • Shared genetic etiology underlying Alzheimer's disease and major depressive disorder. 
  • Shared genetic etiology underlying late-onset Alzheimer's disease and posttraumatic stress syndrome. 
  • Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies. 
  • Shared genetic variants for polypoidal choroidal vasculopathy and typical neovascular age-related macular degeneration in East Asians. 
  • Shared genetics underlying epidemiological association between endometriosis and ovarian cancer. 
  • Shared heritability and functional enrichment across six solid cancers. 
  • Shrinkage estimation for robust and efficient screening of single-SNP association from case-control genome-wide association studies. 
  • Significance of MDM2 and P14 ARF polymorphisms in susceptibility to differentiated thyroid carcinoma. 
  • Significance of microRNA-related variants in susceptibility to recurrence of oropharyngeal cancer patients after definitive radiotherapy. 
  • Significant associations of mismatch repair gene polymorphisms with clinical outcome of pancreatic cancer. 
  • Significant effect of homologous recombination DNA repair gene polymorphisms on pancreatic cancer survival. 
  • Simple models of genomic variation in human SNP density. 
  • Single Nucleotide Polymorphism Heritability of a General Psychopathology Factor in Children. 
  • Single Nucleotide Polymorphisms in CBLB, a Regulator of T-Cell Response, Predict Radiation Pneumonitis and Outcomes After Definitive Radiotherapy for Non-Small-Cell Lung Cancer. 
  • Single nucleotide polymorphism at rs1982073:T869C of the TGFbeta 1 gene is associated with the risk of radiation pneumonitis in patients with non-small-cell lung cancer treated with definitive radiotherapy. 
  • Single nucleotide polymorphisms act as modifiers and correlate with the development of medullary and simultaneous medullary/papillary thyroid carcinomas in 2 large, non-related families with the RET V804M proto-oncogene mutation. 
  • Single nucleotide polymorphisms and inherited risk of chronic lymphocytic leukemia among African Americans. 
  • Single nucleotide polymorphisms in multiple novel thrombospondin genes may be associated with familial premature myocardial infarction. 
  • Single nucleotide polymorphisms in the TP53 region and susceptibility to invasive epithelial ovarian cancer. 
  • Single nucleotide polymorphisms of RecQ1, RAD54L, and ATM genes are associated with reduced survival of pancreatic cancer. 
  • Single nucleotide polymorphisms of gemcitabine metabolic genes and pancreatic cancer survival and drug toxicity. 
  • Single nucleotide polymorphisms of matrix metallopeptidase 3 and risk of gliomas in a Chinese Han population. 
  • Single nucleotide variation in the TP53 3' untranslated region in diffuse large B-cell lymphoma treated with rituximab-CHOP: a report from the International DLBCL Rituximab-CHOP Consortium Program. 
  • Single-Nucleotide Polymorphisms Associated With Age-Related Macular Degeneration and Lesion Phenotypes in the Comparison of Age-Related Macular Degeneration Treatments Trials. 
  • Single-nucleotide polymorphisms at the TP53-binding or responsive promoter regions of BAX and BCL2 genes and risk of squamous cell carcinoma of the head and neck. 
  • Single-nucleotide polymorphisms of DNA damage response genes are associated with overall survival in patients with pancreatic cancer. 
  • Single-nucleotide polymorphisms of stemness genes predicted to regulate RNA splicing, microRNA and oncogenic signaling are associated with prostate cancer survival. 
  • Site frequency spectra from genomic SNP surveys. 
  • Smoking quit success genotype score predicts quit success and distinct patterns of developmental involvement with common addictive substances. 
  • Social environment influences the relationship between genotype and gene expression in wild baboons. 
  • Social support in older individuals: the role of the BDNF Val66Met polymorphism. 
  • Somatic Mutation Allelic Ratio Test Using ddPCR (SMART-ddPCR): An Accurate Method for Assessment of Preferential Allelic Imbalance in Tumor DNA. 
  • Somatic deletions of genes regulating MSH2 protein stability cause DNA mismatch repair deficiency and drug resistance in human leukemia cells. 
  • Somatic, positive and negative domains of the Center for Epidemiological Studies Depression (CES-D) scale: a meta-analysis of genome-wide association studies. 
  • Spatial pattern of nucleotide polymorphism indicates molecular adaptation in the bryophyte Sphagnum fimbriatum. 
  • Specific genetic polymorphisms of IL10-592 AA and IL10-819 TT genotypes lead to the key role for inducing docetaxel-induced liver injury in breast cancer patients. 
  • Spink2 modulates apoptotic susceptibility and is a candidate gene in the Rgcs1 QTL that affects retinal ganglion cell death after optic nerve damage. 
  • Sporadic, Global Linkage Disequilibrium Between Unlinked Segregating Sites. 
  • Statistical models for haplotype sharing in case-parent trio data. 
  • Stereoselective Bupropion Hydroxylation by Cytochrome P450 CYP2B6 and Cytochrome P450 Oxidoreductase Genetic Variants. 
  • Steroid 5-alpha-reductase type 2 (SRD5A2) V89L and A49T polymorphisms and sporadic prostate cancer risk: a meta-analysis. 
  • Stress, COMT Polymorphisms, and Depressive Symptoms in Older Australian Women: An Exploratory Study. 
  • Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes. 
  • Structural variants can be more informative for disease diagnostics, prognostics and translation than current SNP mapping and exon sequencing. 
  • Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. 
  • Study of a US cohort supports the role of ZNF644 and high-grade myopia susceptibility. 
  • Subacute methotrexate neurotoxicity and cerebral venous sinus thrombosis in a 12-year-old with acute lymphoblastic leukemia and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism: homocysteine-mediated methotrexate neurotoxicity via direct endothelial injury. 
  • Substantial multiclass transmitted drug resistance and drug-relevant polymorphisms among treatment-naïve behaviorally HIV-infected youth. 
  • Sugar-Sweetened Beverage Consumption May Modify Associations Between Genetic Variants in the CHREBP (Carbohydrate Responsive Element Binding Protein) Locus and HDL-C (High-Density Lipoprotein Cholesterol) and Triglyceride Concentrations. 
  • Suggestive association between the C825T polymorphism of the G-protein beta3 subunit gene (GNB3) and clinical improvement with antipsychotics in schizophrenia. 
  • Summary of contributions to GAW15 Group 13: candidate gene association studies. 
  • Support for TGFB1 as a susceptibility gene for high myopia in individuals of Chinese descent. 
  • Surgical necrotizing enterocolitis in extremely premature neonates is associated with genetic variations in an intergenic region of chromosome 8. 
  • Survey of variation in human transcription factors reveals prevalent DNA binding changes. 
  • Susceptibility Loci for Clinical Coronary Artery Disease and Subclinical Coronary Atherosclerosis Throughout the Life-Course. 
  • Susceptibility loci of CNOT6 in the general mRNA degradation pathway and lung cancer risk-A re-analysis of eight GWASs. 
  • Susceptibility locus for clinical and subclinical coronary artery disease at chromosome 9p21 in the multi-ethnic ADVANCE study. 
  • Sympatric speciation of spiny mice, Acomys, unfolded transcriptomically at Evolution Canyon, Israel. 
  • Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease. 
  • Systematic Functional Testing of Rare Variants: Contributions of CFI to Age-Related Macular Degeneration. 
  • Systematic Review and Meta-analysis: Gene Association Studies in Neonatal Sepsis. 
  • Systematic protein-protein interaction and pathway analyses in the idiopathic inflammatory myopathies. 
  • Systems genetics identifies a role for Cacna2d1 regulation in elevated intraocular pressure and glaucoma susceptibility. 
  • T (brachyury) gene duplication confers major susceptibility to familial chordoma. 
  • T locus shows no evidence for linkage disequilibrium or mutation in American Caucasian neural tube defect families. 
  • TERC is not a major gene in human neural tube defects. 
  • TET2 binds the androgen receptor and loss is associated with prostate cancer. 
  • TGFβ1 Polymorphisms Predict Distant Metastasis-Free Survival in Patients with Inoperable Non-Small-Cell Lung Cancer after Definitive Radiotherapy. 
  • TLR5 participates in the TLR4 receptor complex and promotes MyD88-dependent signaling in environmental lung injury. 
  • TNF, LTA and TGFB1 genotype distributions among acute graft-vs-host disease subsets after HLA-matched unrelated hematopoietic stem cell transplantation: a pilot study. 
  • TOLLIP, MUC5B, and the Response to N-Acetylcysteine among Individuals with Idiopathic Pulmonary Fibrosis. 
  • TOMM40 and APOE: Requirements for replication studies of association with age of disease onset and enrichment of a clinical trial. 
  • TSPAN5, ERICH3 and selective serotonin reuptake inhibitors in major depressive disorder: pharmacometabolomics-informed pharmacogenomics. 
  • Tagging SNPs in non-homologous end-joining pathway genes and risk of glioma. 
  • Tagging single nucleotide polymorphisms in MBD4 are associated with risk of lung cancer in a Chinese population. 
  • Tagging single nucleotide polymorphisms in cell cycle control genes and susceptibility to invasive epithelial ovarian cancer. 
  • Tagging single nucleotide polymorphisms in excision repair cross-complementing group 1 (ERCC1) and risk of primary lung cancer in a Chinese population. 
  • Tagging single nucleotide polymorphisms in phosphoinositide-3-kinase-related protein kinase genes involved in DNA damage "checkpoints" and lung cancer susceptibility. 
  • Taking cardiovascular genetic association studies to the next level. 
  • Targeted Exome Sequencing of the Cancer Genome in Patients with Very High-risk Bladder Cancer. 
  • Taste perception: how sweet it is (to be transcribed by you). 
  • Telomere structure and maintenance gene variants and risk of five cancer types. 
  • Temporal encoding of bacterial identity and traits in growth dynamics. 
  • Testing Rare-Variant Association without Calling Genotypes Allows for Systematic Differences in Sequencing between Cases and Controls. 
  • Testing for causality between systematically identified risk factors and glioma: a Mendelian randomization study. 
  • Testing the Relative Performance of Data Adaptive Prediction Algorithms: A Generalized Test of Conditional Risk Differences. 
  • Testosterone Pathway Genetic Polymorphisms in Relation to Primary Open-Angle Glaucoma: An Analysis in Two Large Datasets. 
  • The 1p13.3 LDL (C)-associated locus shows large effect sizes in young populations. 
  • The ACTN3 R577X Polymorphism Is Associated with Cardiometabolic Fitness in Healthy Young Adults. 
  • The ARMS2 A69S variant and bilateral advanced age-related macular degeneration. 
  • The ATXN1 and TRIM31 genes are related to intelligence in an ADHD background: evidence from a large collaborative study totaling 4,963 subjects. 
  • The Alzheimer's associated 5' region of the SORL1 gene cis regulates SORL1 transcripts expression. 
  • The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory. 
  • The COMT Val158Met polymorphism and temporal lobe morphometry in healthy adults. 
  • The DNA sequence of the human X chromosome. 
  • The Duffy antigen receptor for chemokines null promoter variant does not influence HIV-1 acquisition or disease progression. 
  • The Effect of Gene Alterations and Tyrosine Kinase Inhibition on Survival and Cause of Death in Patients With Adenocarcinoma of the Lung and Brain Metastases. 
  • The Effect of the Relationship of APOE Polymorphisms and Cerebral Vasospasm on Functional Outcomes in Children With Traumatic Brain Injury. 
  • The G72/G30 gene complex and cognitive abnormalities in schizophrenia. 
  • The Genetics of Endophenotypes of Neurofunction to Understand Schizophrenia (GENUS) consortium: A collaborative cognitive and neuroimaging genetics project. 
  • The Genetics of Success: How Single-Nucleotide Polymorphisms Associated With Educational Attainment Relate to Life-Course Development. 
  • The International HapMap Project. 
  • The MUC5B promoter polymorphism and telomere length in patients with chronic hypersensitivity pneumonitis: an observational cohort-control study. 
  • The Marquesans at the fringes of the Austronesian expansion. 
  • The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers. 
  • The Polygenic and Monogenic Basis of Blood Traits and Diseases. 
  • The RIG-I-like helicase receptor MDA5 (IFIH1) is involved in the host defense against Candida infections. 
  • The SLCO1B1*5 genetic variant is associated with statin-induced side effects. 
  • The Shared Genetic Architectures Between Lung Cancer and Multiple Polygenic Phenotypes in Genome-Wide Association Studies. 
  • The TOMM40 poly-T rs10524523 variant is associated with cognitive performance among non-demented elderly with type 2 diabetes. 
  • The VEGF -634G>C promoter polymorphism is associated with risk of gastric cancer. 
  • The XPD Asp312Asn and Lys751Gln polymorphisms, corresponding haplotype, and pancreatic cancer risk. 
  • The association between genetically elevated polyunsaturated fatty acids and risk of cancer. 
  • The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25,000 subjects. 
  • The association of PTPN22 rs2476601 with juvenile idiopathic arthritis is specific to females. 
  • The association of single-nucleotide polymorphisms in the oxytocin receptor and G protein-coupled receptor kinase 6 (GRK6) genes with oxytocin dosing requirements and labor outcomes. 
  • The brain-derived neurotrophic factor VAL66MET polymorphism and cerebral white matter hyperintensities in late-life depression. 
  • The characterization of twenty sequenced human genomes. 
  • The clinical pharmacogenomics implementation consortium: CPIC guideline for SLCO1B1 and simvastatin-induced myopathy. 
  • The complex genetics of gait speed: genome-wide meta-analysis approach. 
  • The contribution of common CYP2A6 alleles to variation in nicotine metabolism among European-Americans. 
  • The effect of SNCA 3' region on the levels of SNCA-112 splicing variant. 
  • The effect of TOMM40 poly-T length on gray matter volume and cognition in middle-aged persons with APOE ε3/ε3 genotype. 
  • The effect of aprepitant and race on the pharmacokinetics of cyclophosphamide in breast cancer patients. 
  • The effect of genotype on methotrexate polyglutamate variability in juvenile idiopathic arthritis and association with drug response. 
  • The effects of the TOMM40 poly-T alleles on Alzheimer's disease phenotypes. 
  • The endothelial protein C receptor (PROCR) Ser219Gly variant and risk of common thrombotic disorders: a HuGE review and meta-analysis of evidence from observational studies. 
  • The factor XII -4C>T variant and risk of common thrombotic disorders: A HuGE review and meta-analysis of evidence from observational studies. 
  • The favorable IFNL3 genotype escapes mRNA decay mediated by AU-rich elements and hepatitis C virus-induced microRNAs. 
  • The functional IGFBP7 promoter -418G>A polymorphism and risk of head and neck cancer. 
  • The functional promoter polymorphism (-842G>C) in the PIN1 gene is associated with decreased risk of breast cancer in non-Hispanic white women 55 years and younger. 
  • The future of cardiothoracic anesthesia. 
  • The genetic architecture of gene expression levels in wild baboons. 
  • The genetic architecture of local adaptation and reproductive isolation in sympatry within the Mimulus guttatus species complex. 
  • The genetic contributions of SNCA and LRRK2 genes to Lewy Body pathology in Alzheimer's disease. 
  • The genetic regulatory signature of type 2 diabetes in human skeletal muscle. 
  • The genetics of POAG in black South Africans: a candidate gene association study. 
  • The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. 
  • The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans. 
  • The genomic consequences of adaptive divergence and reproductive isolation between species of manakins. 
  • The impact of disregarding family structure on genome-wide association analysis of complex diseases in cohorts with simple pedigrees. 
  • The importance of being connected. 
  • The marriage of quantitative genetics and cell biology: a novel screening approach reveals people have genetically encoded variation in microtubule stability. 
  • The miR-184 binding-site rs8126 T>C polymorphism in TNFAIP2 is associated with risk of gastric cancer. 
  • The missense of smell: functional variability in the human odorant receptor repertoire. 
  • The pivotal role of the complement system in aging and age-related macular degeneration: hypothesis re-visited. 
  • The prognostic values of CYP2B6 genetic polymorphisms and metastatic sites for advanced breast cancer patients treated with docetaxel and thiotepa. 
  • The relationship between methylenetetrahydrofolate reductase polymorphism and hematological malignancy. 
  • The relationship of polymorphisms in ABCC2 and SLCO1B3 with docetaxel pharmacokinetics and neutropenia: CALGB 60805 (Alliance). 
  • The role of Exo1p exonuclease in DNA end resection to generate gene conversion tracts in Saccharomyces cerevisiae. 
  • The role of KRAS rs61764370 in invasive epithelial ovarian cancer: implications for clinical testing. 
  • The role of polymorphisms in circadian pathway genes in breast tumorigenesis. 
  • The rs4774 CIITA missense variant is associated with risk of systemic lupus erythematosus. 
  • The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm. 
  • The shared genetic architecture between epidemiological and behavioral traits with lung cancer. 
  • The significance of single nucleotide polymorphism rs2070770 in CD20 gene in Chinese patients with diffuse large B-cell lymphoma. 
  • The standing pool of genomic structural variation in a natural population of Mimulus guttatus. 
  • The ubiquilin 1 gene and Alzheimer's disease. 
  • The uncharacterized gene 1700093K21Rik and flanking regions are correlated with reproductive isolation in the house mouse, Mus musculus. 
  • The use of single-nucleotide polymorphism maps in pharmacogenomics. 
  • The vitamin D receptor gene as a determinant of survival in pancreatic cancer patients: Genomic analysis and experimental validation. 
  • The what, where, and when of catechol-O-methyltransferase. 
  • The worry about clopidogrel "nonresponsiveness": identification and treatment in the post-percutaneous coronary intervention patient. 
  • Therapeutic Targets for Heart Failure Identified Using Proteomics and Mendelian Randomization. 
  • Three novel genetic variants in NRF2 signaling pathway genes are associated with pancreatic cancer risk. 
  • Three polymorphisms in cytochrome P450 1B1 (CYP1B1) gene and breast cancer risk: a meta-analysis. 
  • Thrombomodulin gene variants are associated with increased mortality after coronary artery bypass surgery in replicated analyses. 
  • Thrombospondin-1 gene polymorphism is associated with estimated pulmonary artery pressure in patients with sickle cell anemia. 
  • Tissue-specific genetic control of splicing: implications for the study of complex traits. 
  • Toll-like Receptor 4 Pathway Polymorphisms Interact with Pollution to Influence Asthma Diagnosis and Severity. 
  • Toll-like receptor 1 polymorphisms increase susceptibility to candidemia. 
  • Toll-like receptor 3 polymorphism rs3775291 is not associated with choroidal neovascularization or polypoidal choroidal vasculopathy in Chinese subjects. 
  • Total zinc intake may modify the glucose-raising effect of a zinc transporter (SLC30A8) variant: a 14-cohort meta-analysis. 
  • Toward deciphering the mechanistic role of variations in the Rep1 repeat site in the transcription regulation of SNCA gene. 
  • Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation. 
  • Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin. 
  • Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. 
  • Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders. 
  • Transancestral mapping and genetic load in systemic lupus erythematosus. 
  • Transcriptome-Wide Analysis Identifies Novel Associations With Blood Pressure. 
  • Transcriptome-Wide Association Study Identifies New Candidate Susceptibility Genes for Glioma. 
  • Transcriptome-Wide Association Study of Blood Cell Traits in African Ancestry and Hispanic/Latino Populations. 
  • Transethnic Evaluation Identifies Low-Frequency Loci Associated With 25-Hydroxyvitamin D Concentrations. 
  • Transethnic genome-wide scan identifies novel Alzheimer's disease loci. 
  • Transferability and fine-mapping of glucose and insulin quantitative trait loci across populations: CARe, the Candidate Gene Association Resource. 
  • Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia. 
  • Transformation of alkylating regimen of thiotepa into tepa determines the disease progression through GSTP1 gene polymorphism for metastatic breast cancer patients receiving thiotepa containing salvage chemotherapy. 
  • Translating Alzheimer's disease-associated polymorphisms into functional candidates: a survey of IGAP genes and SNPs. 
  • Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies. 
  • Tumor necrosis factor-alpha-238G>A promoter polymorphism is associated with increased risk of new hemorrhage in the natural course of patients with brain arteriovenous malformations. 
  • Tumor necrosis factor-α induced protein 8 polymorphism and risk of non-Hodgkin's lymphoma in a Chinese population: a case-control study. 
  • Tumour necrosis factor receptor II polymorphism and juvenile idiopathic arthritis. 
  • Two HLA Class II Gene Variants Are Independently Associated with Pediatric Osteosarcoma Risk. 
  • Two genes on A/J chromosome 18 are associated with susceptibility to Staphylococcus aureus infection by combined microarray and QTL analyses. 
  • Two new susceptibility loci for Kawasaki disease identified through genome-wide association analysis. 
  • Two novel PRKCI polymorphisms and prostate cancer risk in an Eastern Chinese Han population. 
  • Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma. 
  • Type 2 Diabetes Genetic Variants and Risk of Diabetic Retinopathy. 
  • Uncoupling associations of risk alleles with endophenotypes and phenotypes: insights from the ApoB locus and heart-related traits. 
  • Uncovering precision phenotype-biomarker associations in traumatic brain injury using topological data analysis. 
  • Understanding the genetics of APOE and TOMM40 and role of mitochondrial structure and function in clinical pharmacology of Alzheimer's disease. 
  • Unisexual and heterosexual meiotic reproduction generate aneuploidy and phenotypic diversity de novo in the yeast Cryptococcus neoformans. 
  • Use of single nucleotide polymorphism arrays to identify a novel region of loss on chromosome 6q in squamous cell carcinomas of the oral cavity. 
  • VKORC1 haplotypes in five East-Asian populations and Indians. 
  • Validating genetic risk associations for ovarian cancer through the international Ovarian Cancer Association Consortium. 
  • Validation of genome-wide prostate cancer associations in men of African descent. 
  • Validation of prostate cancer risk-related loci identified from genome-wide association studies using family-based association analysis: evidence from the International Consortium for Prostate Cancer Genetics (ICPCG). 
  • Validation study of genetic associations with coronary artery disease on chromosome 3q13-21 and potential effect modification by smoking. 
  • Variants in CXCR4 associate with juvenile idiopathic arthritis susceptibility. 
  • Variants in Notch signalling pathway genes, PSEN1 and MAML2, predict overall survival in Chinese patients with epithelial ovarian cancer. 
  • Variants in PPP3R1 and MAPT are associated with more rapid functional decline in Alzheimer's disease: the Cache County Dementia Progression Study. 
  • Variants in angiopoietin-2 (ANGPT2) contribute to variation in nocturnal oxyhaemoglobin saturation level. 
  • Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility. 
  • Variants in melanocortin 1 receptor gene contribute to risk of melanoma--a direct sequencing analysis in a Texas population. 
  • Variants in nucleotide excision repair core genes and susceptibility to recurrence of squamous cell carcinoma of the oropharynx. 
  • Variants in the ITPA gene protect against ribavirin-induced hemolytic anemia and decrease the need for ribavirin dose reduction. 
  • Variants in the ITPA gene protect against ribavirin-induced hemolytic anemia in HIV/HCV-coinfected patients with all HCV genotypes. 
  • Variants in toll-like receptors 2 and 9 influence susceptibility to pulmonary tuberculosis in Caucasians, African-Americans, and West Africans. 
  • Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk. 
  • Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia. 
  • Variation in NF-κB signaling pathways and survival in invasive epithelial ovarian cancer. 
  • Variation in PTX3 is associated with primary graft dysfunction after lung transplantation. 
  • Variation in glucose homeostasis traits associated with P2RX7 polymorphisms in mice and humans. 
  • Variation in the gene encoding the serotonin 2A receptor is associated with outcome of antidepressant treatment. 
  • Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of alpha-synuclein. 
  • Variation within DNA repair pathway genes and risk of multiple sclerosis. 
  • Vascular tone pathway polymorphisms in relation to primary open-angle glaucoma. 
  • Vitamin D insufficiency increases risk of chronic pain among African Americans experiencing motor vehicle collision. 
  • Vitamin D receptor (VDR) polymorphisms and risk of ovarian cancer in Caucasian and African American women. 
  • Vitamin D-responsive SGPP2 variants associated with lung cell expression and lung function. 
  • Whole exome sequencing identifies a mutation for a novel form of corneal intraepithelial dyskeratosis. 
  • Whole genome sequence analysis of pulmonary function and COPD in 19,996 multi-ethnic participants. 
  • Whole genome sequencing identifies circulating Beijing-lineage Mycobacterium tuberculosis strains in Guatemala and an associated urban outbreak. 
  • Whole-Genome Analysis Illustrates Global Clonal Population Structure of the Ubiquitous Dermatophyte Pathogen Trichophyton rubrum. 
  • Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol. 
  • Whole-exome sequencing implicates UBE3D in age-related macular degeneration in East Asian populations. 
  • Whole-exome sequencing of a pedigree segregating asthma. 
  • Whole-genome sequencing of bloodstream Staphylococcus aureus isolates does not distinguish bacteraemia from endocarditis. 
  • Workshop on cancer biometrics: identifying biomarkers and surrogates of cancer in patients: a meeting held at the Masur Auditorium, National Institutes of Health. 
  • XRCC2 and XRCC3 gene polymorphism and risk of pancreatic cancer. 
  • XRCC3 Thr241Met polymorphism and breast cancer risk: a meta-analysis. 
  • XRCC3 haplotypes and risk of gliomas in a Chinese population: a hospital-based case-control study. 
  • Xenobiotic-Metabolizing gene polymorphisms and ovarian cancer risk. 
  • [Human chromosome 8p11 (CHRNB3-CHRNA6) region gene polymorphisms and susceptibility to lung cancer in Chinese Han population]. 
  • beta(2)-Adrenergic receptor and adenylate cyclase gene polymorphisms affect sickle red cell adhesion. 
  • c-Kit is essential for alveolar maintenance and protection from emphysema-like disease in mice. 
  • fastJT: An R package for robust and efficient feature selection for machine learning and genome-wide association studies. 
  • miR-449b rs10061133 and miR-4293 rs12220909 polymorphisms are associated with decreased esophageal squamous cell carcinoma in a Chinese population. 
  • p14ARF genetic polymorphisms and susceptibility to second primary malignancy in patients with index squamous cell carcinoma of the head and neck. 
  • rs495139 in the TYMS-ENOSF1 Region and Risk of Ovarian Carcinoma of Mucinous Histology. 
  • μ-Opioid Receptor Gene A118 G Variants and Persistent Pain Symptoms Among Men and Women Experiencing Motor Vehicle Collision. 
  • μ-Opioid receptor gene A118G polymorphism predicts survival in patients with breast cancer. 
• 

  Keywords of People

  • Alberts, Susan C., Robert F. Durden Distinguished Professor of Biology, Duke Science & Society
  • Bennett, Vann, George Barth Geller Distinguished Professor of Molecular Biology, Duke Cancer Institute
  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Bowes Rickman, Catherine, George and Geneva Boguslavsky Distinguished Professor of Eye Research, Cell Biology
  • Buckley, Rebecca Hatcher, James Buren Sidbury Distinguished Professor Emeritus of Pediatrics, in the School of Medicine, Pediatrics, Allergy and Immunology
  • Clyde, Merlise, Professor of Statistical Science, Statistical Science
  • Li, Yi-Ju, Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics
  • Liu, Yutao, Adjunct Assistant Professor in the Department of Medicine, Medicine, Medical Genetics
  • McLendon, Roger Edwin, Professor of Pathology, Pathology
  • Milano, Carmelo Alessio, Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery, Surgery, Cardiovascular and Thoracic Surgery
  • Moorman, Patricia Gripka, Professor Emeritus in Family Medicine and Community Health, Duke Cancer Institute
  • Mruthyunjaya, Prithvi, Adjunct Associate Professor in the Department of Ophthalmology, Ophthalmology, Vitreoretinal Diseases & Surgery
  • O'Connor, Christopher Michael, Adjunct Professor in the Department of Medicine, Medicine, Clinical Pharmacology
  • Pang, Herbert, Adjunct Assistant Professor in the Department of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics
  • Pitt, Geoffrey Stuart, Adjunct Professor in the Department of Medicine, Medicine, Cardiology
  • Reddy, Timothy E, Associate Professor of Biostatistics & Bioinformatics,, Molecular Genetics and Microbiology
  • Wray, Gregory Allan, Professor of Biology, Evolutionary Anthropology
  • Zhong, Xiaoping, Professor of Pediatrics, Integrative Immunobiology