cdc25 Phosphatases
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Subject Areas on Research
- A role for PP1 in the Cdc2/Cyclin B-mediated positive feedback activation of Cdc25.
- Activation of MAPK/ERK signaling by Burkholderia pseudomallei cycle inhibiting factor (Cif).
- Cell cycle. Checking two steps.
- Computational design, synthesis and biological evaluation of para-quinone-based inhibitors for redox regulation of the dual-specificity phosphatase Cdc25B.
- Control of mitotic exit by PP2A regulation of Cdc25C and Cdk1.
- Experimental validation of the docking orientation of Cdc25 with its Cdk2-CycA protein substrate.
- Identification of highly potent and selective Cdc25 protein phosphatases inhibitors from miniaturization click-chemistry-based combinatorial libraries.
- Involvement of the MKK6-p38gamma cascade in gamma-radiation-induced cell cycle arrest.
- Maintenance of G2 arrest in the Xenopus oocyte: a role for 14-3-3-mediated inhibition of Cdc25 nuclear import.
- Mechanism of Cdc25B phosphatase with the small molecule substrate p-nitrophenyl phosphate from QM/MM-MFEP calculations.
- Nucleo-cytoplasmic interactions that control nuclear envelope breakdown and entry into mitosis in the sea urchin zygote.
- PP1 control of M phase entry exerted through 14-3-3-regulated Cdc25 dephosphorylation.
- Phosphatases driving mitosis: pushing the gas and lifting the brakes.
- Posttranslational control of Cdc25 degradation terminates Drosophila's early cell-cycle program.
- Requirement of the prolyl isomerase Pin1 for the replication checkpoint.
- Role for the PP2A/B56delta phosphatase in regulating 14-3-3 release from Cdc25 to control mitosis.
- Short-term integration of Cdc25 dynamics controls mitotic entry during Drosophila gastrulation.
- The mitotic peptidyl-prolyl isomerase, Pin1, interacts with Cdc25 and Plx1.
- When the checkpoints have gone: insights into Cdc25 functional activation.