rab GTP-Binding Proteins
-
Subject Areas on Research
- A conserved retromer-independent function for RAB-6.2 in C. elegans epidermis integrity.
- A cross-species approach using an in vivo evaluation platform in mice demonstrates that sequence variation in human RABEP2 modulates ischemic stroke outcomes.
- A galactosylceramide binding domain is involved in trafficking of CLN3 from Golgi to rafts via recycling endosomes.
- A mutation in Sec15l1 causes anemia in hemoglobin deficit (hbd) mice.
- Analysis of the Rab GTPase Interactome in Dendritic Cells Reveals Anti-microbial Functions of the Rab32 Complex in Bacterial Containment.
- Autophagy inhibitor Vacuolin-1 interferes with lipid-based small interference RNA delivery.
- Brefeldin A rapidly disrupts plasma membrane polarity by blocking polar sorting in common endosomes of MDCK cells.
- CHML promotes liver cancer metastasis by facilitating Rab14 recycle.
- Chemical Modulation of Endocytic Sorting Augments Adeno-associated Viral Transduction.
- Clinical and functional findings in choroideremia due to complete deletion of the CHM gene.
- Collaboration between Distinct Rab Small GTPase Trafficking Circuits Mediates Bacterial Clearance from the Bladder Epithelium.
- Colocalization of different influenza viral RNA segments in the cytoplasm before viral budding as shown by single-molecule sensitivity FISH analysis.
- Congenital hemophagocytic lymphohistiocytosis presenting as thrombocytopenia in a newborn.
- Constitutive internalization of the leucine-rich G protein-coupled receptor-5 (LGR5) to the trans-Golgi network.
- Coxsackievirus entry across epithelial tight junctions requires occludin and the small GTPases Rab34 and Rab5.
- Cytokine stimulation promotes glucose uptake via phosphatidylinositol-3 kinase/Akt regulation of Glut1 activity and trafficking.
- Definition of distinct compartments in polarized Madin-Darby canine kidney (MDCK) cells for membrane-volume sorting, polarized sorting and apical recycling.
- ELKS1 controls mast cell degranulation by regulating the transcription of Stxbp2 and Syntaxin 4 via Kdm2b stabilization.
- Elevated Urinary Rab10 Phosphorylation in Idiopathic Parkinson Disease.
- Free cholesterol accumulation in macrophage membranes activates Toll-like receptors and p38 mitogen-activated protein kinase and induces cathepsin K.
- Genetic background influences LRRK2-mediated Rab phosphorylation in the rat brain.
- Integrative genomics identifies RAB23 as an invasion mediator gene in diffuse-type gastric cancer.
- Interaction between bud-site selection and polarity-establishment machineries in budding yeast.
- Isoprenylcysteine carboxyl methyltransferase deficiency in mice.
- LRRK2 and Rab10 coordinate macropinocytosis to mediate immunological responses in phagocytes.
- LRRK2 phosphorylates membrane-bound Rabs and is activated by GTP-bound Rab7L1 to promote recruitment to the trans-Golgi network.
- Large-scale profiling of Rab GTPase trafficking networks: the membrome.
- Low oxygen saturation during sleep reduces CD1D and RAB20 expressions that are reversed by CPAP therapy.
- Molecular characterization of CLPT1, a SEC4-like Rab/GTPase of the phytopathogenic fungus Colletotrichum lindemuthianum which is regulated by the carbon source.
- Notochord vacuoles are lysosome-related organelles that function in axis and spine morphogenesis.
- RAB-10-Dependent Membrane Transport Is Required for Dendrite Arborization.
- Rab10 regulates membrane transport through early endosomes of polarized Madin-Darby canine kidney cells.
- Rab11 helps maintain apical crumbs and adherens junctions in the Drosophila embryonic ectoderm.
- TLR4-mediated expulsion of bacteria from infected bladder epithelial cells.
- The secretory pathway in control of endoplasmic reticulum homeostasis.
- The yeast Rab GTPase Ypt1 modulates unfolded protein response dynamics by regulating the stability of HAC1 RNA.
- Transiently expressed ATG16L1 inhibits autophagosome biogenesis and aberrantly targets RAB11-positive recycling endosomes.
- Yeast Cdc42 functions at a late step in exocytosis, specifically during polarized growth of the emerging bud.
-
Keywords of People
- West, Andrew Bradley, Professor of Pharmacology and Cancer Biology, Cell Biology