RNA, Small Cytoplasmic

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  Subject Areas on Research

  • 60-kDa Ro protein autoepitopes identified using recombinant polypeptides. 
  • A six-month-old boy with neonatal lupus and cardiac enlargement. 
  • Antigenicity of a recombinant Ro (SS-A) fusion protein. 
  • Detection of differentially abundant cell subpopulations in scRNA-seq data. 
  • Estimation of immune cell content in tumor using single-cell RNA-seq reference data. 
  • Inhibition of estrogen signaling in myeloid cells increases tumor immunity in melanoma. 
  • Modification of lupus-associated 60-kDa Ro protein with the lipid oxidation product 4-hydroxy-2-nonenal increases antigenicity and facilitates epitope spreading. 
  • Molecular analysis of the 60-kDa human Ro ribonucleoprotein. 
  • Molecular composition of Ro small ribonucleoprotein complexes in human cells. Intracellular localization of the 60- and 52-kD proteins. 
  • Molecular structure of the La and Ro autoantigens and their use in autoimmune diagnostics. 
  • RCA2: a scalable supervised clustering algorithm that reduces batch effects in scRNA-seq data. 
  • Selective small antigenic structures are capable of inducing widespread autoimmunity which closely mimics the humoral fine specificity of human SLE. 
  • Specificity of autoantibodies for recombinant 60-kd and 52-kd Ro autoantigens. 
  • The fine specificity of monoclonal anti-DNA antibodies induced in normal mice by immunization with bacterial DNA.