Parkinsonian Disorders
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Subject Areas on Research
- Atypical parkinsonism and motor neuron syndrome in a Biosphere 2 participant: a possible complication of chronic hypoxia and carbon monoxide toxicity?
- Beta Frequency Oscillations in the Subthalamic Nucleus Are Not Sufficient for the Development of Symptoms of Parkinsonian Bradykinesia/Akinesia in Rats.
- Characterizing effects of subthalamic nucleus deep brain stimulation on methamphetamine-induced circling behavior in hemi-Parkinsonian rats.
- Cognitive impairment in rapid-onset dystonia-parkinsonism.
- Deep brain stimulation of the subthalamic nucleus reestablishes neuronal information transmission in the 6-OHDA rat model of parkinsonism.
- Deep brain stimulation reduces neuronal entropy in the MPTP-primate model of Parkinson's disease.
- Dopamine: from pharmacology to molecular biology and back.
- Effect of levodopa priming on dopamine neuron transplant efficacy and induction of abnormal involuntary movements in parkinsonian rats.
- Estimation of D2-like receptor occupancy by dopamine in the putamen of hemiparkinsonian Monkeys.
- Failure to suppress low-frequency neuronal oscillatory activity underlies the reduced effectiveness of random patterns of deep brain stimulation.
- Frequency-dependent, transient effects of subthalamic nucleus deep brain stimulation on methamphetamine-induced circling and neuronal activity in the hemiparkinsonian rat.
- Genetics of parkin-linked disease.
- In vitro polymerization of tau protein monitored by laser light scattering: method and application to the study of FTDP-17 mutants.
- Increased expression of the dopamine transporter leads to loss of dopamine neurons, oxidative stress and l-DOPA reversible motor deficits.
- LC/MS analysis of cardiolipins in substantia nigra and plasma of rotenone-treated rats: Implication for mitochondrial dysfunction in Parkinson's disease.
- Localization of Parkinson's disease-associated LRRK2 in normal and pathological human brain.
- Mitochondrial DNA damage: molecular marker of vulnerable nigral neurons in Parkinson's disease.
- Model-based deconstruction of cortical evoked potentials generated by subthalamic nucleus deep brain stimulation.
- Mutations in ATP13A2 (PARK9) are associated with an amyotrophic lateral sclerosis-like phenotype, implicating this locus in further phenotypic expansion.
- PHARMACOLOGICAL ASPECTS OF PARKINSONISM.
- Quantitative 1H magnetic resonance spectroscopic imaging determines therapeutic immunization efficacy in an animal model of Parkinson's disease.
- Racial and socioeconomic disparities in parkinsonism.
- Rapid-onset dystonia-parkinsonism associated with the I758S mutation of the ATP1A3 gene: a neuropathologic and neuroanatomical study of four siblings.
- Spinal cord stimulation restores locomotion in animal models of Parkinson's disease.
- The gene responsible for PARK6 Parkinson's disease, PINK1, does not influence common forms of parkinsonism.
- The tau N279K exon 10 splicing mutation recapitulates frontotemporal dementia and parkinsonism linked to chromosome 17 tauopathy in a mouse model.
- Therapeutic immunization protects dopaminergic neurons in a mouse model of Parkinson's disease.
- Urinary LRRK2 phosphorylation predicts parkinsonian phenotypes in G2019S LRRK2 carriers.
- Work toward real-time control of a cortical neural prothesis.
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Keywords of People
- Nicolelis, Miguel Angelo L., Duke School of Medicine Professor in Neuroscience, Psychology and Neuroscience