Matrix Metalloproteinase 2
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Subject Areas on Research
- (Pro)renin receptor is expressed in human retinal pigment epithelium and participates in extracellular matrix remodeling.
- A blood-based biomarker panel to risk-stratify mild traumatic brain injury.
- A novel fibrotic disorder associated with increased dermal fibroblast proliferation and downregulation of genes of the microfibrillar network.
- A plasma membrane-associated component of ovarian adenocarcinoma cells enhances the catalytic efficiency of matrix metalloproteinase-2.
- Activation of matrix metalloproteinases following anti-Aβ immunotherapy; implications for microhemorrhage occurrence.
- Adventitial endothelial implants reduce matrix metalloproteinase-2 expression and increase luminal diameter in porcine arteriovenous grafts.
- Alterations in human trabecular meshwork cell homeostasis by selenium.
- Angiotensin II-induced MMP-2 activity and MMP-14 and basigin protein expression are mediated via the angiotensin II receptor type 1-mitogen-activated protein kinase 1 pathway in retinal pigment epithelium: implications for age-related macular degeneration.
- Angiotensin II-induced hypertension regulates AT1 receptor subtypes and extracellular matrix turnover in mouse retinal pigment epithelium.
- Bone morphogenetic proteins induce pancreatic cancer cell invasiveness through a Smad1-dependent mechanism that involves matrix metalloproteinase-2.
- Bone-related genes expressed in advanced malignancies induce invasion and metastasis in a genetically defined human cancer model.
- Characterization of gelatinases linked to extracellular matrix invasion in ovarian adenocarcinoma: purification of matrix metalloproteinase 2.
- Cytoskeletal dependence of adenosine triphosphate release by human trabecular meshwork cells.
- Deletion of p47phox attenuates angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-deficient mice.
- Dendritic cell transmigration through brain microvessel endothelium is regulated by MIP-1alpha chemokine and matrix metalloproteinases.
- Derlin-1 is overexpressed in non-small cell lung cancer and promotes cancer cell invasion via EGFR-ERK-mediated up-regulation of MMP-2 and MMP-9.
- Different roles for matrix metalloproteinase-2 and matrix metalloproteinase-9 in the pathogenesis of cardiac allograft rejection.
- Doxycycline alters collagen composition following ventral hernia repair.
- Doxycycline shows dose-dependent changes in hernia repair strength after mesh repair.
- Effect of cisplatin and BCNU on MMP-2 levels in human glioblastoma cell lines in vitro.
- Effects of cardiotonic steroids on trabecular meshwork cells: search for mediator of ouabain-enhanced outflow facility.
- Effects of radiation on the levels of MMP-2, MMP-9 and TIMP-1 during morphogenic glial-endothelial cell interactions.
- Effects of titanium particle size on osteoblast functions in vitro and in vivo.
- Estrogen receptor beta protects against in vivo injury in RPE cells.
- Female gender, estrogen loss, and Sub-RPE deposit formation in aged mice.
- Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts.
- Increased blood-brain barrier permeability and altered tight junctions in experimental diabetes in the rat: contribution of hyperglycaemia and matrix metalloproteinases.
- Independent beta-arrestin2 and Gq/protein kinase Czeta pathways for ERK stimulated by angiotensin type 1A receptors in vascular smooth muscle cells converge on transactivation of the epidermal growth factor receptor.
- Influence of actin cytoskeletal integrity on matrix metalloproteinase-2 activation in cultured human trabecular meshwork cells.
- Integrin-linked kinase regulates osteopontin-dependent MMP-2 and uPA expression to convey metastatic function in murine mammary epithelial cancer cells.
- Interleukin-13 induces collagen type-1 expression through matrix metalloproteinase-2 and transforming growth factor-β1 in airway fibroblasts in asthma.
- MMP-14 and TIMP-2 overexpression protects against hydroquinone-induced oxidant injury in RPE: implications for extracellular matrix turnover.
- Matrix metalloprotease regulation of neuropathic pain.
- Matrix metalloproteinases in patients with myocardial infarction and percutaneous revascularization.
- Mechanisms of action of rapamycin in gliomas.
- Nicotine increases size and severity of experimental choroidal neovascularization.
- Nitric oxide-mediated regulation of β-amyloid clearance via alterations of MMP-9/TIMP-1.
- Nonlethal oxidant injury to human retinal pigment epithelium cells causes cell membrane blebbing but decreased MMP-2 activity.
- Osteopontin silencing by small interfering RNA suppresses in vitro and in vivo CT26 murine colon adenocarcinoma metastasis.
- PRDX6 attenuates oxidative stress- and TGFbeta-induced abnormalities of human trabecular meshwork cells.
- Proteomics characterization of cell membrane blebs in human retinal pigment epithelium cells.
- Rac1/Pak1/p38/MMP-2 Axis Regulates Angiogenesis in Ovarian Cancer.
- Regulation of angiotensin II receptors and extracellular matrix turnover in human retinal pigment epithelium: role of angiotensin II.
- Regulation of estrogen receptors and MMP-2 expression by estrogens in human retinal pigment epithelium.
- Repetitive nonlethal oxidant injury to retinal pigment epithelium decreased extracellular matrix turnover in vitro and induced sub-RPE deposits in vivo.
- Retinal pigment epithelium protection from oxidant-mediated loss of MMP-2 activation requires both MMP-14 and TIMP-2.
- Role of Matrix Metalloproteinases-1 and -2 in Interleukin-13-Suppressed Elastin in Airway Fibroblasts in Asthma.
- Secreted Hsp90 is a novel regulator of the epithelial to mesenchymal transition (EMT) in prostate cancer.
- Selenium's effects on MMP-2 and TIMP-1 secretion by human trabecular meshwork cells.
- Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis.
- Structural remodelling in heart failure: gelatinase induction.
- Study of gastric fluid induced cytokine and chemokine expression in airway smooth muscle cells and airway remodeling.
- Subtype specific estrogen receptor action protects against changes in MMP-2 activation in mouse retinal pigmented epithelial cells.
- Suppressor and activator functions mediated by a repeated heptad sequence in the liver fatty acid-binding protein gene (Fabpl). Effects on renal, small intestinal, and colonic epithelial cell gene expression in transgenic mice.
- TGF-beta: a new role for an old AktTOR.
- The role of β-arrestin2-dependent signaling in thoracic aortic aneurysm formation in a murine model of Marfan syndrome.
- Thrombin-cleaved COOH(-) terminal osteopontin peptide binds with cyclophilin C to CD147 in murine breast cancer cells.
- Thrombospondin-1 and thrombospondin-2 mRNA and TSP-1 and TSP-2 protein expression in uterine fibroids and correlation to the genes COL1A1 and COL3A1 and to the collagen cross-link hydroxyproline.
- Trabodenoson, an Adenosine Mimetic With A1 Receptor Selectivity Lowers Intraocular Pressure by Increasing Conventional Outflow Facility in Mice.
- Type IV collagenase (matrix metalloproteinase-2 and -9) in prostate cancer.
- Unique response profile of trabecular meshwork cells to the novel selective glucocorticoid receptor agonist, GW870086X.
- Upregulation of VEGF-A and CD24 gene expression by the tGLI1 transcription factor contributes to the aggressive behavior of breast cancer cells.
- Use of a multiple-enzyme/multiple-reagent assay system to quantify activity levels in samples containing mixtures of matrix metalloproteinases.
- Vibratory loading decreases extracellular matrix and matrix metalloproteinase gene expression in rabbit annulus cells.
- Vitamin E inhibits abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice.