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Subject Areas on Research
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Activation of Gz attenuates Rap1-mediated differentiation of PC12 cells.
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Activation of the mitogen-activated protein kinase pathway through p75NTR: a common mechanism for the neurotrophin family.
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Adeno-Associated Viral Vector (Serotype 2)-Nerve Growth Factor for Patients With Alzheimer Disease: A Randomized Clinical Trial.
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Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition.
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Chlorpyrifos affects phenotypic outcomes in a model of mammalian neurodevelopment: critical stages targeting differentiation in PC12 cells.
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Diabetic cystopathy correlates with a long-term decrease in nerve growth factor levels in the bladder and lumbosacral dorsal root Ganglia.
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Differences between the effect of anisotropic and isotropic laminin and nerve growth factor presenting scaffolds on nerve regeneration across long peripheral nerve gaps.
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Distinction between differentiation, cell cycle, and apoptosis signals in PC12 cells by the nerve growth factor mutant delta9/13, which is selective for the p75 neurotrophin receptor.
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Diverse neurotoxicants converge on gene expression for neuropeptides and their receptors in an in vitro model of neurodifferentiation: effects of chlorpyrifos, diazinon, dieldrin and divalent nickel in PC12 cells.
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Erbin suppresses the MAP kinase pathway.
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Human carbonic anhydrase-8 AAV8 gene therapy inhibits nerve growth factor signaling producing prolonged analgesia and anti-hyperalgesia in mice.
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Hypothermic reperfusion after cardiac arrest augments brain-derived neurotrophic factor activation.
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Immunoneutralization of nerve growth factor in lumbosacral spinal cord reduces bladder hyperreflexia in spinal cord injured rats.
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Influence of terminal nerve branch size on motor neuron regeneration accuracy.
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Knockout of the norepinephrine transporter and pharmacologically diverse antidepressants prevent behavioral and brain neurotrophin alterations in two chronic stress models of depression.
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Modeling the developmental neurotoxicity of nicotine in vitro: cell acquisition, growth and viability in PC12 cells.
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NGF inhibits M/KCNQ currents and selectively alters neuronal excitability in subsets of sympathetic neurons depending on their M/KCNQ current background.
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NGF is essential for hippocampal plasticity and learning.
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Nerve growth factor specifically stimulates translation of eukaryotic elongation factor 1A-1 (eEF1A-1) mRNA by recruitment to polyribosomes in PC12 cells.
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Nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 levels in human amniotic fluid.
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Nerve growth factor: structure, function and therapeutic implications for Alzheimer's disease.
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Nerves Regulate Cardiomyocyte Proliferation and Heart Regeneration.
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Neurotrophin Signaling Is Required for Glucose-Induced Insulin Secretion.
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Nicotine is a developmental neurotoxicant and neuroprotectant: stage-selective inhibition of DNA synthesis coincident with shielding from effects of chlorpyrifos.
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PTSD Susceptibility and Challenges: Pathophysiological Consequences of Behavioral Symptoms.
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Phosphatidylinositol 3-kinase activates ERK in primary sensory neurons and mediates inflammatory heat hyperalgesia through TRPV1 sensitization.
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Plasma carnitine in HIV-associated neuropathy.
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Prenatal choline supplementation increases NGF levels in the hippocampus and frontal cortex of young and adult rats.
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Severity of HIV-associated neuropathy is associated with plasma HIV-1 RNA levels.
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Targeting of neurotrophic factors, their receptors, and signaling pathways in the developmental neurotoxicity of organophosphates in vivo and in vitro.
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The role of bladder afferent pathways in bladder hyperactivity induced by the intravesical administration of nerve growth factor.
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Tissue-engineered scaffolds are effective alternatives to autografts for bridging peripheral nerve gaps.
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Topical Recombinant Human Nerve Growth Factor (Cenegermin) for Neurotrophic Keratopathy: A Multicenter Randomized Vehicle-Controlled Pivotal Trial.
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Transcriptional profiles for glutamate transporters reveal differences between organophosphates but similarities with unrelated neurotoxicants.
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Unc-51-like kinase 1/2-mediated endocytic processes regulate filopodia extension and branching of sensory axons.
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Unrelated developmental neurotoxicants elicit similar transcriptional profiles for effects on neurotrophic factors and their receptors in an in vitro model.
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p38 MAPK activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia.