Nucleic Acid Amplification Techniques
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Subject Areas on Research
- A c-Myc and surface CD19 signaling amplification loop promotes B cell lymphoma development and progression in mice.
- A genome-wide study of preferential amplification/hybridization in microarray-based pooled DNA experiments.
- A lyophilized colorimetric RT-LAMP test kit for rapid, low-cost, at-home molecular testing of SARS-CoV-2 and other pathogens.
- A paired-end sequencing strategy to map the complex landscape of transcription initiation.
- Advantages of mRNA amplification for microarray analysis.
- Array-based comparative genomic hybridization from formalin-fixed, paraffin-embedded breast tumors.
- Assessing the utility of whole genome amplified DNA for next-generation molecular ecology.
- Complementary techniques: RNA amplification for gene profiling analysis.
- Cost-effectiveness analysis of the gen-probe amplified mycobacterium tuberculosis direct test as used routinely on smear-positive respiratory specimens.
- Deciphering human immunodeficiency virus type 1 transmission and early envelope diversification by single-genome amplification and sequencing.
- Deep-RACE: Comprehensive Search for Novel ncRNAs Associated to a Specific Locus.
- Detection of frequent allelic loss on proximal chromosome 17q in sporadic breast carcinoma using microsatellite length polymorphisms.
- Detection of pathogen-specific antibodies by loop-mediated isothermal amplification.
- Digital microfluidics: a future technology in the newborn screening laboratory?
- Direct carrier testing in 14 families with haemophilia B.
- Direct fluorescence detection of RNA on microarrays by surface-initiated enzymatic polymerization.
- Dynamic and heterogeneous mutations to fluconazole resistance in Cryptococcus neoformans.
- Early experience with the use of hepatitis C antibody-positive, nucleic acid testing-negative donors in lung transplantation.
- Epigenetic detection of human chromosome 14 uniparental disomy.
- Evaluation of the Abbott m2000rt RealTime HIV-1 assay with manual sample preparation compared with the ROCHE COBAS AmpliPrep/AMPLICOR HIV-1 MONITOR v1.5 using specimens from East Africa.
- GeneXpert MTB/Rif to Diagnose Tuberculous Meningitis: Perhaps the First Test but not the Last.
- Genomic amplification with transcript sequencing.
- Identification of the single base change causing the callipyge muscle hypertrophy phenotype, the only known example of polar overdominance in mammals.
- Impact of molecular testing on reported Clostridoides difficile infection rates.
- Investigation of the basis of virulence in serotype A strains of Cryptococcus neoformans from apparently immunocompetent individuals.
- Little qualitative RNA misexpression in sterile male F1 hybrids of Drosophila pseudoobscura and D. persimilis.
- Mapping of sex determination loci on the white campion (Silene latifolia) Y chromosome using amplified fragment length polymorphism.
- Microarray-based comparison of three amplification methods for nanogram amounts of total RNA.
- Pelvic inflammatory disease.
- Performance of amplified DNA in an Illumina GoldenGate BeadArray assay.
- Public health costs for tuberculosis suspects in Wake County, North Carolina, United States.
- Simultaneous Evaluation of Diagnostic Assays for Pharyngeal and Rectal Neisseria gonorrhoeae and Chlamydia trachomatis Using a Master Protocol.
- The complexities of Xpert® MTB/RIF interpretation.
- Trachoma: an update on prevention, diagnosis, and treatment.
- Transmitted antiretroviral drug resistance among acute and recent HIV infections in North Carolina from 1998 to 2007.