Cyclophilin A
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Subject Areas on Research
- Cyclophilin A is localized to the nucleus and controls meiosis in Saccharomyces cerevisiae.
- Discovery of novel cyclophilin A ligands using an H/D exchange- and mass spectrometry-based strategy.
- Glutathione peroxidase-deficient smooth muscle cells cause paracrine activation of normal smooth muscle cells via cyclophilin A.
- HIV-1 infection: fooling the gatekeeper.
- Mass spectrometry-based thermal shift assay for protein-ligand binding analysis.
- Potential implications of Apolipoprotein E in early brain injury after experimental subarachnoid hemorrhage: Involvement in the modulation of blood-brain barrier integrity.
- Prolyl isomerases in yeast.
- Protein expression profiling identifies macrophage migration inhibitory factor and cyclophilin a as potential molecular targets in non-small cell lung cancer.
- Stable RNA interference-mediated suppression of cyclophilin A diminishes non-small-cell lung tumor growth in vivo.
- Stable isotope labeling strategy for protein-ligand binding analysis in multi-component protein mixtures.
- StableIsotope Labeling with Amino Acids in Cell Culture (SILAC)-based strategy for proteome-wide thermodynamic analysis of protein-ligand binding interactions.
- Targeting the cyclophilin domain of Ran-binding protein 2 (Ranbp2) with novel small molecules to control the proteostasis of STAT3, hnRNPA2B1 and M-opsin.
- Thermodynamic analysis of cyclosporin a binding to cyclophilin a in a lung tumor tissue lysate.
- Throughput and efficiency of a mass spectrometry-based screening assay for protein-ligand binding detection.
- Transgene induced co-suppression during vegetative growth in Cryptococcus neoformans.
- Translating biomarkers into clinical practice: prognostic implications of cyclophilin A and macrophage migratory inhibitory factor identified from protein expression profiles in non-small cell lung cancer.
- Two cyclophilin A homologs with shared and distinct functions important for growth and virulence of Cryptococcus neoformans.
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Keywords of People
- Patz Jr., Edward F., James and Alice Chen Distinguished Professor of Radiology, Pathology