Myeloid Cells
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Subject Areas on Research
- miR-146a -Traf6 regulatory axis controls autoimmunity and myelopoiesis, but is dispensable for hematopoietic stem cell homeostasis and tumor suppression.
- A PK2/Bv8/PROK2 antagonist suppresses tumorigenic processes by inhibiting angiogenesis in glioma and blocking myeloid cell infiltration in pancreatic cancer.
- A reactive metabolite as an immune suppressant.
- A20 in Myeloid Cells Protects Against Hypertension by Inhibiting Dendritic Cell-Mediated T-Cell Activation.
- Abrogation of α-synuclein-mediated dopaminergic neurodegeneration in LRRK2-deficient rats.
- Allogeneic splenocyte transfer and lipopolysaccharide inhalations induce differential T cell expansion and lung injury: a novel model of pulmonary graft-versus-host disease.
- Autophagy enhances NFκB activity in specific tissue macrophages by sequestering A20 to boost antifungal immunity.
- Bone marrow chimeras and c-fms conditional ablation (Mafia) mice reveal an essential role for resident myeloid cells in lipopolysaccharide/TLR4-induced corneal inflammation.
- CX3CR1 deficiency accelerates the development of retinopathy in a rodent model of type 1 diabetes.
- CaMKK2 in myeloid cells is a key regulator of the immune-suppressive microenvironment in breast cancer.
- Cellular FLIP Inhibits Myeloid Cell Activation by Suppressing Selective Innate Signaling.
- Coactivation of NF-κB and Notch signaling is sufficient to induce B-cell transformation and enables B-myeloid conversion.
- Conditional HIF-1 induction produces multistage neovascularization with stage-specific sensitivity to VEGFR inhibitors and myeloid cell independence.
- Differential Immune Microenvironments and Response to Immune Checkpoint Blockade among Molecular Subtypes of Murine Medulloblastoma.
- Distinct hematopoietic progenitor compartments are delineated by the expression of aldehyde dehydrogenase and CD34.
- Diverse genetic-driven immune landscapes dictate tumor progression through distinct mechanisms.
- Dominant-negative IKZF1 mutations cause a T, B, and myeloid cell combined immunodeficiency.
- Erythropoietin mediates terminal granulocytic differentiation of committed myeloid cells with ectopic erythropoietin receptor expression.
- Flow Cytometric Analysis of Myeloid Cells in Human Blood, Bronchoalveolar Lavage, and Lung Tissues.
- Hepatic stellate cells undermine the allostimulatory function of liver myeloid dendritic cells via STAT3-dependent induction of IDO.
- Improving the Quality and Reproducibility of Flow Cytometry in the Lung. An Official American Thoracic Society Workshop Report.
- In Vitro Pre-Clinical Validation of Suicide Gene Modified Anti-CD33 Redirected Chimeric Antigen Receptor T-Cells for Acute Myeloid Leukemia.
- Isolation and Characterization of Human Lung Myeloid Cells.
- Leukocyte composition of human breast cancer.
- Lumbar Myeloid Cell Trafficking into Locomotor Networks after Thoracic Spinal Cord Injury.
- Myeloid Cells in the Central Nervous System.
- Myeloid Growth Factors, Version 2.2017, NCCN Clinical Practice Guidelines in Oncology.
- Myeloid neoplasms secondary to plasma cell myeloma: an intrinsic predisposition or therapy-related phenomenon? A clinicopathologic study of 41 cases and correlation of cytogenetic features with treatment regimens.
- Myeloid-derived suppressors cells (MDSC) correlate with clinicopathologic factors and pathologic complete response (pCR) in patients with urothelial carcinoma (UC) undergoing cystectomy.
- Neutrophils with myeloid derived suppressor function deplete arginine and constrain T cell function in septic shock patients.
- Notch-Induced Myeloid Reprogramming in Spontaneous Pancreatic Ductal Adenocarcinoma by Dual Genetic Targeting.
- Opposing actions of renal tubular- and myeloid-derived porcupine in obstruction-induced kidney fibrosis.
- Osteopontin expression is essential for interferon-alpha production by plasmacytoid dendritic cells.
- Overexpression of the Notch target genes Hes in vivo induces lymphoid and myeloid alterations.
- Preemptive donor apoptotic cell infusions induce IFN-γ-producing myeloid-derived suppressor cells for cardiac allograft protection.
- Radiation combined with thermal injury induces immature myeloid cells.
- Recombinant human granulocyte colony-stimulating factor therapy for patients with neutropenia and/or neutrophil dysfunction secondary to glycogen storage disease type 1b.
- Selective predisposition to bacterial infections in IRAK-4-deficient children: IRAK-4-dependent TLRs are otherwise redundant in protective immunity.
- Skewing of the population balance of lymphoid and myeloid cells by secreted and intracellular osteopontin.
- Spliceosomal component Sf3b1 is essential for hematopoietic differentiation in zebrafish.
- The G2019S LRRK2 mutation increases myeloid cell chemotactic responses and enhances LRRK2 binding to actin-regulatory proteins.
- The cholesterol metabolite 27 hydroxycholesterol facilitates breast cancer metastasis through its actions on immune cells.
- The impact of chronic blood-brain barrier breach on intracortical electrode function.
- The lung is protected from spontaneous inflammation by autophagy in myeloid cells.
- The myeloid growth factors.
- Treatment of Cyclosporin A retains host defense against invasive pulmonary aspergillosis in a non-immunosuppressive murine model by preserving the myeloid cell population.
- Twist1 in Infiltrating Macrophages Attenuates Kidney Fibrosis via Matrix Metallopeptidase 13-Mediated Matrix Degradation.
- VEGF is essential for hypoxia-inducible factor-mediated neovascularization but dispensable for endothelial sprouting.
- Which comes first: the antigen or the adjuvant?
- Yolk-sac-derived macrophages regulate fetal testis vascularization and morphogenesis.
- β-Catenin-regulated myeloid cell adhesion and migration determine wound healing.
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Keywords of People
- McLendon, Roger Edwin, Professor of Pathology, Pathology
- Shinohara, Mari L., Associate Professor of Immunology, Immunology