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Subject Areas on Research
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A Beautiful Day in the Neighborhood: Application of Single-Cell Transcriptomics to Unravel Liver Cell Heterogeneity in Diseased Human Livers.
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A CRISPR Screen Identifies the Cell Polarity Determinant Crumbs 3 as an Adeno-associated Virus Restriction Factor in Hepatocytes.
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A controlled-release strategy for the generation of cross-linked hydrogel microstructures.
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A critical role for ChREBP-mediated FGF21 secretion in hepatic fructose metabolism.
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A family of hierarchically self-assembling linear-dendritic hybrid polymers for highly efficient targeted gene delivery.
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A genetic view of iron homeostasis.
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A laboratory-adapted HCV JFH-1 strain is sensitive to neutralization and can gradually escape under the selection pressure of neutralizing human plasma.
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A20 modulates lipid metabolism and energy production to promote liver regeneration.
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A20 protects mice from D-galactosamine/lipopolysaccharide acute toxic lethal hepatitis.
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A20 protects mice from lethal liver ischemia/reperfusion injury by increasing peroxisome proliferator-activated receptor-alpha expression.
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A20 protects mice from lethal radical hepatectomy by promoting hepatocyte proliferation via a p21waf1-dependent mechanism.
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Ablation of c-FLIP in hepatocytes enhances death-receptor mediated apoptosis and toxic liver injury in vivo.
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Absence of the SRC-2 coactivator results in a glycogenopathy resembling Von Gierke's disease.
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Accumulation of duct cells with activated YAP parallels fibrosis progression in non-alcoholic fatty liver disease.
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Accumulation of hedgehog-responsive progenitors parallels alcoholic liver disease severity in mice and humans.
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Activin induces hepatocyte cell growth arrest through induction of the cyclin-dependent kinase inhibitor p15INK4B and Sp1.
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Acute organ failure following the loss of anti-apoptotic cellular FLICE-inhibitory protein involves activation of innate immune receptors.
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Acute pancreatitis induces FasL gene expression and apoptosis in the liver.
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Acyl-CoAs are functionally channeled in liver: potential role of acyl-CoA synthetase.
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Adenovirus-mediated gene transfer to nonparenchymal cells in normal and injured liver.
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Aging reduces liver resiliency by dysregulating Hedgehog signaling.
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Akt1 and Akt2 are required for alphabeta thymocyte survival and differentiation.
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An endogenous TNF-alpha antagonist induced by splice-switching oligonucleotides reduces inflammation in hepatitis and arthritis mouse models.
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An in vivo look at vertebrate liver architecture: three-dimensional reconstructions from medaka (Oryzias latipes).
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Anemia of inflammation: the cytokine-hepcidin link.
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Apoptosis and cytokines in non-alcoholic steatohepatitis.
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Aquaglyceroporin AQP9: solute permeation and metabolic control of expression in liver.
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Balancing acts: molecular control of mammalian iron metabolism.
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Benzyl alcohol protects against acetaminophen hepatotoxicity by inhibiting cytochrome P450 enzymes but causes mitochondrial dysfunction and cell death at higher doses.
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Bicarbonate alters cellular responses in respiration assays.
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Carcinogen induced unscheduled DNA synthesis in mouse hepatocytes.
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Cardioprotective proteins upregulated in the liver in response to experimental myocardial ischemia.
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Cell surface F1Fo ATP synthase: a new paradigm?
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Characterization of a canine model of glycogen storage disease type IIIa.
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Chronic ethanol intoxication enhances the production of cytokine-induced neutrophil chemoattractant and macrophage inflammatory protein-2 by hepatocytes after human immunodeficiency virus-1 glycoprotein 120 vaccination.
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Circulating Levels of Soluble Dipeptidyl Peptidase-4 Are Dissociated from Inflammation and Induced by Enzymatic DPP4 Inhibition.
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Coevolution of Adeno-associated Virus Capsid Antigenicity and Tropism through a Structure-Guided Approach.
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Complexity of ballooned hepatocyte feature recognition: Defining a training atlas for artificial intelligence-based imaging in NAFLD.
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Contrast enhanced liver MRI in patients with primary sclerosing cholangitis: inverse appearance of focal confluent fibrosis on delayed phase MR images with hepatocyte specific versus extracellular gadolinium based contrast agents.
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Costaining for keratins 8/18 plus ubiquitin improves detection of hepatocyte injury in nonalcoholic fatty liver disease.
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Critical role of FoxO3a in alcohol-induced autophagy and hepatotoxicity.
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Culture of hepatocytes on fructose-modified chitosan scaffolds.
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Culture of primary rat hepatocytes within porous chitosan scaffolds.
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Cytokines in alcoholic and nonalcoholic steatohepatitis.
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Decreased autophagy and fuel switching occur in a senescent hepatic cell model system.
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Deletion of CaMKK2 from the liver lowers blood glucose and improves whole-body glucose tolerance in the mouse.
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Dengue virus and autophagy.
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Dengue virus-induced autophagy regulates lipid metabolism.
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Determination of glucuronide conjugates of hydroxyl triphenyl phosphate (OH-TPHP) metabolites in human urine and its use as a biomarker of TPHP exposure.
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Developmental Morphogens & Recovery from Alcoholic Liver Disease.
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Diabetic liver injury from streptozotocin is regulated through the caspase-8 homolog cFLIP involving activation of JNK2 and intrahepatic immunocompetent cells.
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Differential AMPK phosphorylation by glucagon and metformin regulates insulin signaling in human hepatic cells.
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Differential susceptibility of fish and rat liver cells to oxidative stress and cytotoxicity upon exposure to prooxidants
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Differentiation of human embryonic stem cells along a hepatic lineage.
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Discovery of Druggable Host Factors Critical to Plasmodium Liver-Stage Infection.
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Disruption of the expression of the proprotein convertase PC7 reduces BDNF production and affects learning and memory in mice.
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Down-regulation of Bmp/Smad signaling by Tmprss6 is required for maintenance of systemic iron homeostasis.
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Downregulation of hepatic betaine:homocysteine methyltransferase (BHMT) expression in taurine-deficient mice is reversed by taurine supplementation in vivo.
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Dual Role of Epidermal Growth Factor Receptor in Liver Injury and Regeneration after Acetaminophen Overdose in Mice.
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Dying for NF-kappaB? Control of cell death by transcriptional regulation of the apoptotic machinery.
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Dynamic MR imaging of the biliary system using hepatocyte-specific contrast agents.
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Dysregulated activation of fetal liver programme in acute liver failure.
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Early induction of hepatic deiodinase type 1 inhibits hepatosteatosis during NAFLD progression.
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Editor's Highlight: Metformin Protects Against Acetaminophen Hepatotoxicity by Attenuation of Mitochondrial Oxidant Stress and Dysfunction.
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Effects of glucagon-like peptide 1 on the hepatic glucose metabolism.
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Effects of liver growth factors on hepadnavirus replication in chronically infected duck hepatocytes.
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Elaboration of tubules with active hedgehog drives parenchymal fibrogenesis in gestational alloimmune liver disease.
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Elevated hepatocyte levels of the Forkhead box A2 (HNF-3beta) transcription factor cause postnatal steatosis and mitochondrial damage.
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Endoplasmic reticulum stress, hepatocyte CD1d and NKT cell abnormalities in murine fatty livers.
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Endotoxin-stimulated Rat Hepatic Stellate Cells Induce Autophagy in Hepatocytes as a Survival Mechanism.
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Enhanced chondrogenic differentiation of embryonic stem cells by coculture with hepatic cells.
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Epidermal growth factor receptor expression and gene copy number in fibrolamellar hepatocellular carcinoma.
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Epigallocatechin-3-gallate (EGCG), a green tea polyphenol, stimulates hepatic autophagy and lipid clearance.
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Epithelial splicing regulatory protein 2-mediated alternative splicing reprograms hepatocytes in severe alcoholic hepatitis.
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Epithelial-to-mesenchymal transitions in the liver.
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Evaluation of multiple mechanism-based toxicity endpoints in primary cultured human hepatocytes for the identification of drugs with clinical hepatotoxicity: Results from 152 marketed drugs with known liver injury profiles.
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Evidence for and against epithelial-to-mesenchymal transition in the liver.
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Expression of mitochondrial membrane-linked SAB determines severity of sex-dependent acute liver injury.
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Fabrication of 3D hepatic tissues by additive photopatterning of cellular hydrogels.
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Fas/FasL play a central role in pancreatitis-induced hepatocyte apoptosis.
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Fasting-induced hepatic production of DHEA is regulated by PGC-1alpha, ERRalpha, and HNF4alpha.
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Fate-mapping evidence that hepatic stellate cells are epithelial progenitors in adult mouse livers.
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Fatty acid elongase-5 (Elovl5) regulates hepatic triglyceride catabolism in obese C57BL/6J mice.
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Fatty liver vulnerability to endotoxin-induced damage despite NF-kappaB induction and inhibited caspase 3 activation.
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Feeding diversified protein sources exacerbates hepatic insulin resistance via increased gut microbial branched-chain fatty acids and mTORC1 signaling in obese mice.
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Fibroblast growth factor 21 mediates specific glucagon actions.
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Fibroblast growth factor 23 directly targets hepatocytes to promote inflammation in chronic kidney disease.
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Fibrolamellar carcinoma of the liver exhibits immunohistochemical evidence of both hepatocyte and bile duct differentiation.
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Fibronectin-mediated hepatocyte shape change reprograms cytochrome P450 2C11 gene expression via an integrin-signaled induction of ribonuclease activity.
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Focal gene induction in the liver of rats by a heat-inducible promoter using focused ultrasound hyperthermia: preliminary results.
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Formyl peptide receptor 2 determines sex-specific differences in the progression of nonalcoholic fatty liver disease and steatohepatitis.
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Fructose consumption as a risk factor for non-alcoholic fatty liver disease.
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GLP-1 receptor activation indirectly reduces hepatic lipid accumulation but does not attenuate development of atherosclerosis in diabetic male ApoE(-/-) mice.
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Gangliosides are essential endosomal receptors for quasi-enveloped and naked hepatitis A virus.
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Genetic networks of liver metabolism revealed by integration of metabolic and transcriptional profiling.
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Genome-wide mapping of DNase hypersensitive sites using massively parallel signature sequencing (MPSS).
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Gestational Alloimmune Liver Disease: A Case Study.
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Glycemic Control Predicts Severity of Hepatocyte Ballooning and Hepatic Fibrosis in Nonalcoholic Fatty Liver Disease.
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Glycerol-3-phosphate acyltransferase (GPAT)-1, but not GPAT4, incorporates newly synthesized fatty acids into triacylglycerol and diminishes fatty acid oxidation.
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Glycogen-targeting subunits and glucokinase differentially affect pathways of glycogen metabolism and their regulation in hepatocytes.
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Granulocytic MDSC with Deficient CCR5 Alleviates Lipogenesis and Inflammation in Nonalcoholic Fatty Liver Disease.
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HNF-4alpha: from MODY to late-onset type 2 diabetes.
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Hedgehog regulates yes-associated protein 1 in regenerating mouse liver.
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Hedgehog signaling maintains resident hepatic progenitors throughout life.
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Hematopoietic stem cells convert into liver cells within days without fusion.
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Hematopoietic-specific Stat5-null mice display microcytic hypochromic anemia associated with reduced transferrin receptor gene expression.
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Hepatic FTO expression is increased in NASH and its silencing attenuates palmitic acid-induced lipotoxicity.
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Hepatic HKDC1 Expression Contributes to Liver Metabolism.
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Hepatic Lipid Catabolism via PPARα-Lysosomal Crosstalk.
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Hepatic Mitochondrial SAB Deletion or Knockdown Alleviates Diet-Induced Metabolic Syndrome, Steatohepatitis, and Hepatic Fibrosis.
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Hepatic accumulation of Hedgehog-reactive progenitors increases with severity of fatty liver damage in mice.
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Hepatic angiomyolipoma and hepatic stellate cells share a similar gene expression profile.
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Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance.
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Hepatic insulin signaling is required for obesity-dependent expression of SREBP-1c mRNA but not for feeding-dependent expression.
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Hepatic mitochondrial dysfunction is a feature of Glycogen Storage Disease Type Ia (GSDIa).
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Hepatitis C Virus Infection Is Inhibited by a Noncanonical Antiviral Signaling Pathway Targeted by NS3-NS4A.
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Hepatitis-C-virus-induced microRNAs dampen interferon-mediated antiviral signaling.
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Hepatocyte Notch activation induces liver fibrosis in nonalcoholic steatohepatitis.
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Hepatocyte nuclear factor-4alpha mediates redox sensitivity of inducible nitric-oxide synthase gene transcription.
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Hepatocyte-specific IL11 cis-signaling drives lipotoxicity and underlies the transition from NAFLD to NASH.
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Hepatocyte-targeted HFE and TFR2 control hepcidin expression in mice.
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Hepatocytic expression of human sodium-taurocholate cotransporting polypeptide enables hepatitis B virus infection of macaques.
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Human FcRn expression and Type I Interferon signaling control Echovirus 11 pathogenesis in mice.
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Hydrophobic nanoparticles improve permeability of cell-encapsulating poly(ethylene glycol) hydrogels while maintaining patternability.
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Hypophosphorylation of the architectural chromatin protein DEK in death-receptor-induced apoptosis revealed by the isotope coded protein label proteomic platform.
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Hypoxia Signaling Cascade for Erythropoietin Production in Hepatocytes.
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Identification of Proteins Bound to Dengue Viral RNA In Vivo Reveals New Host Proteins Important for Virus Replication.
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Immunohistochemical characterization of the hepatic progenitor cell compartment in medaka (Oryzias latipes) following hepatic injury.
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Improved liver lesion conspicuity by increasing the flip angle during hepatocyte phase MR imaging.
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In vitro and in vivo inhibition of malaria parasite infection by monoclonal antibodies against Plasmodium falciparum circumsporozoite protein (CSP).
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In vitro investigation of the hepatobiliary disposition mechanisms of the antifungal agent micafungin in humans and rats.
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In vitro sensitivity testing of minimally passaged and uncultured gliomas with TRAIL and/or chemotherapy drugs.
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Increased hepatic fibrosis and JNK2-dependent liver injury in mice exhibiting hepatocyte-specific deletion of cFLIP.
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Increased production of sonic hedgehog by ballooned hepatocytes.
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Induction of an Inflammatory Response in Primary Hepatocyte Cultures from Mice.
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Induction of autophagy improves hepatic lipid metabolism in glucose-6-phosphatase deficiency.
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Influence of HIV antiretrovirals on methadone N-demethylation and transport.
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Inhibiting Interleukin 11 Signaling Reduces Hepatocyte Death and Liver Fibrosis, Inflammation, and Steatosis in Mouse Models of Nonalcoholic Steatohepatitis.
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Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis.
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Inhibiting xCT/SLC7A11 induces ferroptosis of myofibroblastic hepatic stellate cells but exacerbates chronic liver injury.
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Initial amplification of duck hepatitis B virus covalently closed circular DNA after in vitro infection of embryonic duck hepatocytes is increased by cell cycle progression.
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Integrated Regulation of Hepatic Lipid and Glucose Metabolism by Adipose Triacylglycerol Lipase and FoxO Proteins.
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Interleukin-15 increases hepatic regenerative activity.
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Intestinal Alkaline Phosphatase Attenuates Alcohol-Induced Hepatosteatosis in Mice.
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Is There a Space-Based Technology Solution to Problems with Preclinical Drug Toxicity Testing?
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Kupffer cell-derived Fas ligand plays a role in liver injury and hepatocyte death.
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Lesion detection and assessment of extrahepatic findings in abdominal MRI using hepatocyte specific contrast agents--comparison of Gd-EOB-DTPA and Gd-BOPTA.
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Liver MRI in the hepatocyte phase with gadolinium-EOB-DTPA: does increasing the flip angle improve conspicuity and detection rate of hypointense lesions?
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Liver cell-derived microparticles activate hedgehog signaling and alter gene expression in hepatic endothelial cells.
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Liver injury-on-a-chip: microfluidic co-cultures with integrated biosensors for monitoring liver cell signaling during injury.
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Liver regeneration requires Yap1-TGFβ-dependent epithelial-mesenchymal transition in hepatocytes.
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Liver transplantation for pediatric metabolic disease.
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Liver-specific loss of beta-catenin blocks glutamine synthesis pathway activity and cytochrome p450 expression in mice.
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Liver-specific loss of beta-catenin results in delayed hepatocyte proliferation after partial hepatectomy.
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Liver-specific loss of long chain acyl-CoA synthetase-1 decreases triacylglycerol synthesis and beta-oxidation and alters phospholipid fatty acid composition.
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Loss of ULK1 increases RPS6KB1-NCOR1 repression of NR1H/LXR-mediated Scd1 transcription and augments lipotoxicity in hepatic cells.
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Macroporous Dual-compartment Hydrogels for Minimally Invasive Transplantation of Primary Human Hepatocytes.
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Mathematical model insights into arsenic detoxification.
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Mathematical modeling of triphasic viral dynamics in patients with HBeAg-positive chronic hepatitis B showing response to 24-week clevudine therapy.
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Mechanism of autoinduction of methadone N-demethylation in human hepatocytes.
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Mechanism of efavirenz influence on methadone pharmacokinetics and pharmacodynamics.
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Mechanisms of disease progression in nonalcoholic fatty liver disease.
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Mechanistic insights of rapid liver regeneration after associating liver partition and portal vein ligation for stage hepatectomy.
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Mesenchymal stem cells support growth and organization of host-liver colorectal-tumor organoids and possibly resistance to chemotherapy.
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Metabolism of polybrominated diphenyl ethers (PBDEs) by human hepatocytes in vitro.
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Metabolomic profiling reveals a role for caspase-2 in lipoapoptosis.
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Mitigation of autophagy ameliorates hepatocellular damage following ischemia-reperfusion injury in murine steatotic liver.
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Mito-tempo protects against acute liver injury but induces limited secondary apoptosis during the late phase of acetaminophen hepatotoxicity.
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Mitochondrial biogenesis restores oxidative metabolism during Staphylococcus aureus sepsis.
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Mitochondrial protein adduct and superoxide generation are prerequisites for early activation of c-jun N-terminal kinase within the cytosol after an acetaminophen overdose in mice.
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Mitochondrial protein adducts formation and mitochondrial dysfunction during N-acetyl-m-aminophenol (AMAP)-induced hepatotoxicity in primary human hepatocytes.
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Multiple innate inflammatory responses induced after systemic adenovirus vector delivery depend on a functional complement system.
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Myofibroblastic cells function as progenitors to regenerate murine livers after partial hepatectomy.
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Nitric oxide and redox regulation in the liver: Part I. General considerations and redox biology in hepatitis.
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Nitric oxide and redox regulation in the liver: part II. Redox biology in pathologic hepatocytes and implications for intervention.
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Nitric oxide synthase-2 regulates mitochondrial Hsp60 chaperone function during bacterial peritonitis in mice.
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No detectable DNA excision repair in UV-exposed hepatocytes from two catfish species.
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Non-alcoholic steatohepatitis pathogenesis: role of repair in regulating the disease progression.
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Nonalcoholic Steatohepatitis.
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Norepinephrine and neuropeptide Y promote proliferation and collagen gene expression of hepatic myofibroblastic stellate cells.
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Oncogenic role of the frizzled-7/beta-catenin pathway in hepatocellular carcinoma.
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Optimal timing and diagnostic adequacy of hepatocyte phase imaging with gadoxetate-enhanced liver MRI.
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Osteopontin is a proximal effector of leptin-mediated non-alcoholic steatohepatitis (NASH) fibrosis.
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Oval cells compensate for damage and replicative senescence of mature hepatocytes in mice with fatty liver disease.
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Over-expression of cyclin D1 regulates Cdk4 protein synthesis.
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Overexpression of rat long chain acyl-coa synthetase 1 alters fatty acid metabolism in rat primary hepatocytes.
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Paradoxical activation of transcription factor SREBP1c and de novo lipogenesis by hepatocyte-selective ATP-citrate lyase depletion in obese mice.
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Pathogenesis of Nonalcoholic Steatohepatitis.
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Pathophysiological significance of c-jun N-terminal kinase in acetaminophen hepatotoxicity.
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Peroxide-mediated chromatin remodelling of a nuclear factor kappa B site in the mouse inducible nitric oxide synthase promoter.
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Phenotypic characterization of transgenic Japanese medaka (Oryzias latipes) that express a red fluorescent protein in hepatocytes.
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Plasmodium PK9 Inhibitors Promote Growth of Liver-Stage Parasites.
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Plasmodium parasite exploits host aquaporin-3 during liver stage malaria infection.
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Plasmodium's fight for survival: escaping elimination while acquiring nutrients.
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Prometheus revisited.
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Protocol to Generate Senescent Cells from the Mouse Hepatic Cell Line AML12 to Study Hepatic Aging.
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RNA-Seq Analysis Illuminates the Early Stages of Plasmodium Liver Infection.
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Race and comorbid factors predict nonalcoholic fatty liver disease histopathology in severely obese patients.
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Rapid Disruption of Genes Specifically in Livers of Mice Using Multiplex CRISPR/Cas9 Editing.
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Receptor-selective coactivators as tools to define the biology of specific receptor-coactivator pairs.
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Redefining IL11 as a regeneration-limiting hepatotoxin and therapeutic target in acetaminophen-induced liver injury.
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Redox-mediated upregulation of hepatocyte iNOS transcription requires coactivator PC4.
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Reduced lipoapoptosis, hedgehog pathway activation and fibrosis in caspase-2 deficient mice with non-alcoholic steatohepatitis.
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Reduction of oxidative stress attenuates lipoapoptosis exacerbated by hypoxia in human hepatocytes.
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Regulation of intrahepatic biliary duct morphogenesis by Claudin 15-like b.
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Removal of acetaminophen protein adducts by autophagy protects against acetaminophen-induced liver injury in mice.
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Reply: Is hepatocyte necrosis a good marker of donor liver viability during machine perfusion?
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Resveratrol prevents protein nitration and release of endonucleases from mitochondria during acetaminophen hepatotoxicity.
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Role for cytoplasmic nucleotide hydrolysis in hepatic function and protein synthesis.
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Role for hedgehog signaling in hepatic stellate cell activation and viability.
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Role of the asialoglycoprotein receptor in binding and entry of hepatitis C virus structural proteins in cultured human hepatocytes.
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SENP3-mediated host defense response contains HBV replication and restores protein synthesis.
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STAT-3 overexpression and p21 up-regulation accompany impaired regeneration of fatty livers.
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STAT3-mediated attenuation of CCl4-induced mouse liver fibrosis by the protein kinase inhibitor sorafenib.
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Serine/threonine phosphorylation regulates HNF-4alpha-dependent redox-mediated iNOS expression in hepatocytes.
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Short chain fatty acids induce UCP2-mediated autophagy in hepatic cells.
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Signals from dying hepatocytes trigger growth of liver progenitors.
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Similarities and differences in the pathogenesis of alcoholic and nonalcoholic steatohepatitis.
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Single-cell omics analysis reveals functional diversification of hepatocytes during liver regeneration.
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Somatic Liver Knockout (SLiK): A Quick and Efficient Way to Generate Liver-Specific Knockout Mice Using Multiplex CRISPR/Cas9 Gene Editing.
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Sonic hedgehog is an autocrine viability factor for myofibroblastic hepatic stellate cells.
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Stage-specific and differential notch dependency at the alphabeta and gammadelta T lineage bifurcation.
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Stem cell therapy for liver disease: parameters governing the success of using bone marrow mesenchymal stem cells.
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Studies on the preparation of chitosan microcarriers cross-linked by oxidized lactose and culture of primary hepatocytes.
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Sustained activation of Rac1 in hepatic stellate cells promotes liver injury and fibrosis in mice.
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Sympathetic nervous system inhibition increases hepatic progenitors and reduces liver injury.
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TRPV4 activation of endothelial nitric oxide synthase resists nonalcoholic fatty liver disease by blocking CYP2E1-mediated redox toxicity.
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TWEAK/Fn14 signaling is required for liver regeneration after partial hepatectomy in mice.
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The Golgi Calcium ATPase Pump Plays an Essential Role in Adeno-associated Virus Trafficking and Transduction.
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The discovery of MK-0674, an orally bioavailable cathepsin K inhibitor.
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The diversity and plasticity of adult hepatic progenitor cells and their niche.
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The gap junction inhibitor 2-aminoethoxy-diphenyl-borate protects against acetaminophen hepatotoxicity by inhibiting cytochrome P450 enzymes and c-jun N-terminal kinase activation.
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The glucagon-like peptide-1 receptor agonist Exendin 4 has a protective role in ischemic injury of lean and steatotic liver by inhibiting cell death and stimulating lipolysis.
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The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis.
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The role of Smad3 in mediating mouse hepatic stellate cell activation.
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The role of death effector domain-containing proteins in acute oxidative cell injury in hepatocytes.
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The role of endogenous heme oxygenase in the initiation of liver injury following limb ischemia/reperfusion.
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The role of hepatocyte hemojuvelin in the regulation of bone morphogenic protein-6 and hepcidin expression in vivo.
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The subcellular localization of syntaxin 17 varies among different cell types and is altered in some malignant cells.
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Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy.
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Tight junction proteins claudin-1 and occludin control hepatitis C virus entry and are downregulated during infection to prevent superinfection.
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Treatment response in the PIVENS trial is associated with decreased Hedgehog pathway activity.
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Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms.
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Underlying potential: cellular and molecular determinants of adult liver repair.
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Use of bulleyaconitine A as an adjuvant for prolonged cutaneous analgesia in the rat.
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Viral factors induce Hedgehog pathway activation in humans with viral hepatitis, cirrhosis, and hepatocellular carcinoma.
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Viral infection of human progenitor and liver-derived cells encapsulated in three-dimensional PEG-based hydrogel.
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c-FLIP maintains tissue homeostasis by preventing apoptosis and programmed necrosis.
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p38 Mitogen-activated protein kinase plays a stimulatory role in hepatic gluconeogenesis.
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β-Adrenergic agonist and antagonist regulation of autophagy in HepG2 cells, primary mouse hepatocytes, and mouse liver.
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