Genomics

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  Subject Areas on Research

  • "Good enough solutions" and the genetics of complex diseases. 
  • (Session Introduction) Joint Learning from Multiple Types of Genomic Data 
  • A Bayesian hierarchical model to estimate DNA methylation conservation in colorectal tumors. 
  • A GWAS Study on Liver Function Test Using eMERGE Network Participants. 
  • A Genocentric Approach to Discovery of Mendelian Disorders. 
  • A Genome-Wide Functional Genomics Approach Identifies Susceptibility Pathways to Fungal Bloodstream Infection in Humans. 
  • A Global Collaborative to Advance Genomic Medicine. 
  • A Guide for a Cardiovascular Genomics Biorepository: the CATHGEN Experience. 
  • A Multidimensional Bioinformatic Platform for the Study of Human Response to Surgery. 
  • A Roadmap for the Human Oral and Craniofacial Cell Atlas. 
  • A central support system can facilitate implementation and sustainability of a Classroom-based Undergraduate Research Experience (CURE) in Genomics. 
  • A chromosome-level reference genome and pangenome for barn swallow population genomics. 
  • A coding and non-coding transcriptomic perspective on the genomics of human metabolic disease. 
  • A compendium of promoter-centered long-range chromatin interactions in the human genome. 
  • A comprehensive iterative approach is highly effective in diagnosing individuals who are exome negative. 
  • A computational framework to assess genome-wide distribution of polymorphic human endogenous retrovirus-K In human populations. 
  • A concurrent dual analysis of genomic data augments diagnoses: Experiences of 2 clinical sites in the Undiagnosed Diseases Network. 
  • A content analysis of the views of genetics professionals on race, ancestry, and genetics. 
  • A course-based research experience: how benefits change with increased investment in instructional time. 
  • A draft genome sequence of the elusive giant squid, Architeuthis dux. 
  • A functional genomics predictive network model identifies regulators of inflammatory bowel disease. 
  • A general integrative genomic feature transcription factor binding site prediction method applied to analysis of USF1 binding in cardiovascular disease. 
  • A genomic approach to colon cancer risk stratification yields biologic insights into therapeutic opportunities. 
  • A genomic approach to identify molecular pathways associated with chemotherapy resistance. 
  • A genomic approach to identify regulatory nodes in the transcriptional network of systemic acquired resistance in plants. 
  • A genomic approach to improve prognosis and predict therapeutic response in chronic lymphocytic leukemia. 
  • A genomic strategy to elucidate modules of oncogenic pathway signaling networks. 
  • A genomic- and proteomic-based hypothesis on the eclectic effects of systemic interleukin-2 administration in the context of melanoma-specific immunization. 
  • A genomic-augmented multivariate prognostic model for the survival of natural-killer/T-cell lymphoma patients from an international cohort. 
  • A global approach to tumor immunology. 
  • A global reference for human genetic variation. 
  • A haplotype-resolved genome assembly of the Nile rat facilitates exploration of the genetic basis of diabetes. 
  • A high-density screen for linkage in multiple sclerosis. 
  • A high-quality genome and comparison of short- versus long-read transcriptome of the palaearctic duck Aythya fuligula (tufted duck). 
  • A high-quality, long-read genome assembly of the endangered ring-tailed lemur (Lemur catta). 
  • A high-resolution map of human evolutionary constraint using 29 mammals. 
  • A hybrid bayesian approach for genome-wide association studies on related individuals. 
  • A joint analysis of metabolomics and genetics of breast cancer. 
  • A knowledge network for a dynamic taxonomy of psychiatric disease. 
  • A machine learning approach to radiogenomics of breast cancer: a study of 922 subjects and 529 DCE-MRI features. 
  • A national clinical decision support infrastructure to enable the widespread and consistent practice of genomic and personalized medicine. 
  • A network-heuristic approach to improve the impact of genomic data on drug discovery. 
  • A new analysis tool for individual-level allele frequency for genomic studies. 
  • A novel integrative risk index of papillary thyroid cancer progression combining genomic alterations and clinical factors. 
  • A pathway-based classification of human breast cancer. 
  • A personalized paradigm in the treatment of platinum-resistant ovarian cancer - A cost utility analysis of genomic-based versus cytotoxic therapy. 
  • A proposed approach to accelerate evidence generation for genomic-based technologies in the context of a learning health system. 
  • A research agenda to support the development and implementation of genomics-based clinical informatics tools and resources. 
  • A sampling of methods to study chromosome and genome structure and function. 
  • A study of the repetitive structure and distribution of short motifs in human genomic sequences. 
  • A(r)Ray of hope in analysis of the function and diversity of microbial communities. 
  • AKT1 and neurocognition in schizophrenia. 
  • Abundant raw material for cis-regulatory evolution in humans. 
  • Active learning for computational chemogenomics. 
  • Activity-Dependent Transcription Collaborates with Local Dendritic Translation to Encode Stimulus-Specificity in the Genome Binding of NPAS4. 
  • Acute myeloid leukemia arising from polycythemia vera underwent reversion to chronic phase of myeloproliferative neoplasm status post chemotherapy: Biclonal myeloid neoplasms with genomic evidence of a common early hematopoietic progenitor. 
  • Adaptive evolution drives the diversification of zinc-finger binding domains. 
  • Adaptive sequence divergence forged new neurodevelopmental enhancers in humans. 
  • Addressing underrepresentation in genomics research through community engagement. 
  • Advances in understanding the evolution of fungal genome architecture. 
  • Advancing toxicology research using in vivo high throughput toxicology with small fish models. 
  • Affiliate network members as force amplifiers of genomic medicine research. 
  • American College of Medical Genetics and Genomics: standards and guidelines for documenting suspected consanguinity as an incidental finding of genomic testing. 
  • An Exploration of Fern Genome Space 
  • An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics. 
  • An algorithm for the reconstruction of consensus sequences of ancient segmental duplications and transposon copies in eukaryotic genomes. 
  • An encyclopedia of mouse DNA elements (Mouse ENCODE). 
  • An evaluation of copy number variation detection tools from whole-exome sequencing data. 
  • An integrated encyclopedia of DNA elements in the human genome. 
  • An integrated genomic-based approach to individualized treatment of patients with advanced-stage ovarian cancer. 
  • An integrated map of genetic variation from 1,092 human genomes. 
  • An overview of genomic data analysis. 
  • An overview of lung cancer genomics and proteomics. 
  • An unbiased in vivo functional genomics screening approach in mice identifies novel tumor cell-based regulators of immune rejection. 
  • Analysing breast cancer microarrays from African Americans using shrinkage-based discriminant analysis. 
  • Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. 
  • Ancestry adjustment improves genome-wide estimates of regional intolerance. 
  • Ancient bacterial endosymbionts of insects: Genomes as sources of insight and springboards for inquiry. 
  • Application of an optimized annotation pipeline to the Cryptococcus deuterogattii genome reveals dynamic primary metabolic gene clusters and genomic impact of RNAi loss. 
  • Aquatic models, genomics and chemical risk management. 
  • Arabidopsis functional genomics. 
  • Architecture of the human regulatory network derived from ENCODE data. 
  • Assessing bioequivalence using genomic data. 
  • Assessing the utility of thermodynamic features for microRNA target prediction under relaxed seed and no conservation requirements. 
  • Assessing the utility of whole genome amplified DNA for next-generation molecular ecology. 
  • Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans. 
  • Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. 
  • Association of tumor genomic factors and efficacy for metastasis-directed stereotactic body radiotherapy for oligometastatic colorectal cancer. 
  • Association test using Copy Number Profile Curves (CONCUR) enhances power in rare copy number variant analysis. 
  • Author's Reply. 
  • Automated Nuclear Segmentation in Head and Neck Squamous Cell Carcinoma Pathology Reveals Relationships between Cytometric Features and ESTIMATE Stromal and Immune Scores. 
  • Automated next-generation profiling of genomic alterations in human cancers. 
  • Avian genomes. A flock of genomes. Introduction. 
  • Avianbase: a community resource for bird genomics. 
  • Baby Genomics: Tracing the Evolutionary Changes That Gave Rise to Placentation. 
  • Basic concepts and potential applications of genetics and genomics for cardiovascular and stroke clinicians: a scientific statement from the American Heart Association. 
  • Bayesian consensus clustering. 
  • Bayesian estimation of genomic distance. 
  • Bayesian joint analysis of heterogeneous genomics data. 
  • Bayesian quantitative electrophysiology and its multiple applications in bioengineering. 
  • Best practices and joint calling of the HumanExome BeadChip: the CHARGE Consortium. 
  • Beta-defensin 1, aryl hydrocarbon receptor and plasma kynurenine in major depressive disorder: metabolomics-informed genomics. 
  • Bimodal age distribution at diagnosis in breast cancer persists across molecular and genomic classifications. 
  • Biomarkers for amyotrophic lateral sclerosis. 
  • Biomarkers for equine joint injury and osteoarthritis. 
  • Boechera, a model system for ecological genomics. 
  • Bone-associated gene evolution and the origin of flight in birds. 
  • Breast Cancer Radiogenomics: Current Status and Future Directions. 
  • Breast MRI radiogenomics: Current status and research implications. 
  • Broadening primate genomics: new insights into the ecology and evolution of primate gene regulation. 
  • Building evidence and measuring clinical outcomes for genomic medicine. 
  • Building the evidence base for decision making in cancer genomic medicine using comparative effectiveness research. 
  • Burkitt lymphoma: analysis of the genome. 
  • CANEapp: a user-friendly application for automated next generation transcriptomic data analysis. 
  • COUGER--co-factors associated with uniquely-bound genomic regions. 
  • CRISPR-based methods for high-throughput annotation of regulatory DNA. 
  • Cancer 2015: a longitudinal whole-of-system study of genomic cancer medicine. 
  • Cancer Informatics: New Tools for a Data-Driven Age in Cancer Research. 
  • Cancer genomics: integrating form and function. 
  • Cancer systems biology: exploring cancer-associated genes on cellular networks. 
  • Cardiac function and heart failure. 
  • Cardiovascular Disease: Impact of Biomarkers, Proteomics, and Genomics. 
  • Cascaded Multi-view Canonical Correlation (CaMCCo) for Early Diagnosis of Alzheimer's Disease via Fusion of Clinical, Imaging and Omic Features. 
  • Cases from the Undiagnosed Diseases Network: The continued value of counseling skills in a new genomic era. 
  • Cell cycle-regulated transcription: effectively using a genomics toolbox. 
  • Centromere scission drives chromosome shuffling and reproductive isolation. 
  • ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia. 
  • Challenges and Controversies in Hypertrophic Cardiomyopathy: Clinical, Genomic and Basic Science Perspectives. 
  • Challenges and strategies for implementing genomic services in diverse settings: experiences from the Implementing GeNomics In pracTicE (IGNITE) network. 
  • Characterization of long G4-rich enhancer-associated genomic regions engaging in a novel loop:loop 'G4 Kissing' interaction. 
  • Characterization of metastatic urothelial carcinoma via comprehensive genomic profiling of circulating tumor DNA. 
  • Chromosomal-Level Genome Assembly of the Sea Urchin Lytechinus variegatus Substantially Improves Functional Genomic Analyses. 
  • Chromosome-Level Reference Genomes for Two Strains of Caenorhabditis briggsae: An Improved Platform for Comparative Genomics. 
  • Circulating Tumor Cell Genomic Evolution and Hormone Therapy Outcomes in Men with Metastatic Castration-Resistant Prostate Cancer. 
  • Clinical Applications of the Genomic Landscape of Aggressive Non-Hodgkin Lymphoma. 
  • Clinical and genomic characterization of Low PSA Secretors: a unique subset of metastatic castration resistant prostate cancer. 
  • Clinical application of a scale to assess genomic healthcare empowerment (GEmS): Process and illustrative case examples. 
  • Clinical decisions surrounding genomic and proteomic testing among United States veterans treated for lung cancer within the Veterans Health Administration. 
  • Clinical genomic testing: getting it right. 
  • Clinical genomics in the world of the electronic health record. 
  • Clinical implications of genomic alterations in the tumour and circulation of pancreatic cancer patients. 
  • Clinical pharmacogenomic testing and reporting: A technical standard of the American College of Medical Genetics and Genomics (ACMG). 
  • Clinical sites of the Undiagnosed Diseases Network: unique contributions to genomic medicine and science. 
  • Clinicopathologic Features and Genomic Signature of De Novo CD5 + Diffuse Large B-Cell Lymphoma : A Multicenter Collaborative Study. 
  • Combinatorial Mismatch Scan (CMS) for loci associated with dementia in the Amish. 
  • Communicating genetic and genomic information: health literacy and numeracy considerations. 
  • Comparative Analyses of Chromatin Landscape in White Adipose Tissue Suggest Humans May Have Less Beigeing Potential than Other Primates. 
  • Comparative Genomic Analysis of the Pheromone Receptor Class 1 Family (V1R) Reveals Extreme Complexity in Mouse Lemurs (Genus, Microcebus) and a Chromosomal Hotspot across Mammals. 
  • Comparative and population mitogenomic analyses of Madagascar's extinct, giant 'subfossil' lemurs. 
  • Comparative effectiveness research in cancer genomics and precision medicine: current landscape and future prospects. 
  • Comparative effectiveness research, genomics-enabled personalized medicine, and rapid learning health care: a common bond. 
  • Comparative genome-wide screening identifies a conserved doxorubicin repair network that is diploid specific in Saccharomyces cerevisiae. 
  • Comparative genomic analyses of multi-drug resistant Mycobacterium tuberculosis from Nepal and other geographical locations. 
  • Comparative genomic analysis of fungal genomes reveals intron-rich ancestors. 
  • Comparative genomics and regulatory evolution: conservation and function of the Chs and Apetala3 promoters. 
  • Comparative genomics applied to Mucor species with different lifestyles. 
  • Comparative genomics as a tool for gene discovery. 
  • Comparative genomics in the Brassicaceae: a family-wide perspective. 
  • Comparative genomics of mammalian hibernators using gene networks. 
  • Comparative genomics provides new insights into the diversity, physiology, and sexuality of the only industrially exploited tremellomycete: Phaffia rhodozyma. 
  • Comparative genomics reveals dynamic genome evolution in host specialist ectomycorrhizal fungi. 
  • Comparative genomics reveals insights into avian genome evolution and adaptation. 
  • Comparative genomics reveals molecular features unique to the songbird lineage. 
  • Comparative genomics search for losses of long-established genes on the human lineage. 
  • Comparing methods for detecting multilocus adaptation with multivariate genotype-environment associations. 
  • Comparison of genomics and functional imaging from canine sarcomas treated with thermoradiotherapy predicts therapeutic response and identifies combination therapeutics. 
  • Complete genomic and epigenetic maps of human centromeres. 
  • Complete vertebrate mitogenomes reveal widespread repeats and gene duplications. 
  • Comprehensive Multi-omics Analysis Reveals Mitochondrial Stress as a Central Biological Hub for Spaceflight Impact. 
  • Comprehensive genomic characterization defines human glioblastoma genes and core pathways. 
  • Comprehensive genomic meta-analysis identifies intra-tumoural stroma as a predictor of survival in patients with gastric cancer. 
  • Comprehensive genomic profiling in advanced/metastatic colorectal cancer: number needed to test and budget impact of expanded first line use. 
  • Comprehensive genomic profiling of pancreatic acinar cell carcinomas identifies recurrent RAF fusions and frequent inactivation of DNA repair genes. 
  • Comprehensive genomic studies: emerging regulatory, strategic, and quality assurance challenges for biorepositories. 
  • Comprehensive molecular portraits of human breast tumours. 
  • Computational approach to radiogenomics of breast cancer: Luminal A and luminal B molecular subtypes are associated with imaging features on routine breast MRI extracted using computer vision algorithms. 
  • Computational approaches for inferring 3D conformations of chromatin from chromosome conformation capture data. 
  • Concordance Between Genomic Alterations Detected by Tumor and Germline Sequencing: Results from a Tertiary Care Academic Center Molecular Tumor Board. 
  • Consensus Statement on Circulating Biomarkers for Advanced Prostate Cancer. 
  • Conservation genomic analysis reveals ancient introgression and declining levels of genetic diversity in Madagascar's hibernating dwarf lemurs. 
  • Conserved genomic collinearity as a source of broadly applicable, fast evolving, markers to resolve species complexes: A case study using the lichen-forming genus Peltigera section Polydactylon. 
  • Considering the Benefits and Risks of Research Participants' Access to Sequence Data. 
  • Contrasts between adaptive coding and noncoding changes during human evolution. 
  • Contributions from medical geneticists in clinical trials of genetic therapies: A points to consider statement of the American College of Medical Genetics and Genomics (ACMG). 
  • Conventional Cytogenetic Analysis of Hematologic Neoplasms: A 20-Year Review of Proficiency Test Results From the College of American Pathologists/American College of Medical Genetics and Genomics Cytogenetics Committee. 
  • Copy number variation contributes to cryptic genetic variation in outbreak lineages of Cryptococcus gattii from the North American Pacific Northwest. 
  • Cortical volume abnormalities in posttraumatic stress disorder: an ENIGMA-psychiatric genomics consortium PTSD workgroup mega-analysis. 
  • Cost-Effectiveness of Tumor Genomic Profiling to Guide First-Line Targeted Therapy Selection in Patients With Metastatic Lung Adenocarcinoma. 
  • Cross species genomic analysis identifies a mouse model as undifferentiated pleomorphic sarcoma/malignant fibrous histiocytoma. 
  • Cross-study projections of genomic biomarkers: an evaluation in cancer genomics. 
  • Cross-validation for linear model with unequal variances in genomic analysis. 
  • Cryptococcus neoformans Recovered From Olive Trees (Olea europaea) in Turkey Reveal Allopatry With African and South American Lineages. 
  • DNA patents and diagnostics: not a pretty picture. 
  • DNase-seq predicts regions of rotational nucleosome stability across diverse human cell types. 
  • DOK2 inhibits EGFR-mutated lung adenocarcinoma. 
  • Darwinian genomics and diversity in the tree of life. 
  • Data Harmonization for a Molecularly Driven Health System. 
  • Deciding among green plants for whole genome studies. 
  • Defending information-free genocentrism. 
  • Depside and Depsidone Synthesis in Lichenized Fungi Comes into Focus through a Genome-Wide Comparison of the Olivetoric Acid and Physodic Acid Chemotypes of Pseudevernia furfuracea. 
  • Design and implementation of high-throughput RNAi screens in cultured Drosophila cells. 
  • Design, Assembly, and Characterization of TALE-Based Transcriptional Activators and Repressors. 
  • Detailed assessment of chromosome 22 aberrations in sporadic pheochromocytoma using array-CGH. 
  • Developing a common framework for evaluating the implementation of genomic medicine interventions in clinical care: the IGNITE Network's Common Measures Working Group. 
  • Development and application of a phylogenomic toolkit: resolving the evolutionary history of Madagascar's lemurs. 
  • Development of Competency-based Online Genomic Medicine Training (COGENT). 
  • Developmental single-cell transcriptomics in the Lytechinus variegatus sea urchin embryo. 
  • Diagnosis and management of glycogen storage diseases type VI and IX: a clinical practice resource of the American College of Medical Genetics and Genomics (ACMG). 
  • Diagnostic testing for uniparental disomy: a points to consider statement from the American College of Medical Genetics and Genomics (ACMG). 
  • DictyBase 2013: integrating multiple Dictyostelid species. 
  • Differential alternative RNA splicing and transcription events between tumors from African American and White patients in The Cancer Genome Atlas. 
  • Discordant and heterogeneous clinically relevant genomic alterations in circulating tumor cells vs plasma DNA from men with metastatic castration resistant prostate cancer. 
  • Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome. 
  • Distinguishing hypertrophic cardiomyopathy-associated mutations from background genetic noise. 
  • Donor genomics influence graft events: the effect of donor polymorphisms on acute rejection and chronic allograft nephropathy. 
  • Drosophila genome-wide RNAi screens: are they delivering the promise? 
  • Drosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution. 
  • Dynamic evolution of base composition: causes and consequences in avian phylogenomics. 
  • Ecological genomics of Boechera stricta: identification of a QTL controlling the allocation of methionine- vs branched-chain amino acid-derived glucosinolates and levels of insect herbivory. 
  • Educating future providers of personalized medicine. 
  • Educating healthcare providers in the delivery of genomic medicine. 
  • Embracing the complexity of genomic data for personalized medicine. 
  • Empowering genomic medicine by establishing critical sequencing result data flows: the eMERGE example. 
  • Enabling functional genomics with genome engineering. 
  • Enhancing our brains: Genomic mechanisms underlying cortical evolution. 
  • Ensuring the safe use of genomic medicine in children. 
  • Environmental genomics: a key to understanding biology, pathophysiology and disease. 
  • Epigenetic Heterogeneity in Human Colorectal Tumors Reveals Preferential Conservation And Evidence of Immune Surveillance. 
  • Epigenome-wide association of PTSD from heterogeneous cohorts with a common multi-site analysis pipeline. 
  • Equity in Genomics: A Brief Report on Cardiovascular Health Disparities in African American Adults. 
  • Establishing the value of genomics in medicine: the IGNITE Pragmatic Trials Network. 
  • Estimating genomic coexpression networks using first-order conditional independence. 
  • Evaluating Chromatin Accessibility Differences Across Multiple Primate Species Using a Joint Modeling Approach. 
  • Evaluation of 122 advanced-stage cutaneous squamous cell carcinomas by comprehensive genomic profiling opens the door for new routes to targeted therapies. 
  • Evaluation of right and left ventricular diastolic filling. 
  • Evidence for a single loss of mineralized teeth in the common avian ancestor. 
  • Evidence for sexuality in the opportunistic fungal pathogen Aspergillus fumigatus. 
  • Evidence of causal effect of major depression on alcohol dependence: findings from the psychiatric genomics consortium. 
  • Evolution of genes and genomes on the Drosophila phylogeny. 
  • Evolutionary and biomedical insights from a marmoset diploid genome assembly. 
  • Evolutionary and ecological functional genomics. 
  • Evolutionary and phylogenetic insights from a nuclear genome sequence of the extinct, giant, "subfossil" koala lemur Megaladapis edwardsi. 
  • Evolutionary genomics and adaptive evolution of the Hedgehog gene family (Shh, Ihh and Dhh) in vertebrates. 
  • Evolving Roles of Histologic Evaluation and Molecular/Genomic Profiling in the Management of Endometrial Cancer. 
  • Exercise biology and medicine: innovative research to improve global health. 
  • Expanded Genomic Profiling of Circulating Tumor Cells in Metastatic Breast Cancer Patients to Assess Biomarker Status and Biology Over Time (CALGB 40502 and CALGB 40503, Alliance). 
  • Expanding studies of chromosome structure and function in the era of T2T genomics. 
  • Exploring syntenic conservation across genomes for phylogenetic studies of organisms subjected to horizontal gene transfers: A case study with Cyanobacteria and cyanolichens. 
  • Family history assessment significantly enhances delivery of precision medicine in the genomics era. 
  • Father Knows Best? Small RNA Pathway Controls Endosperm Response to Paternal Genomic Dosage. 
  • Feather development genes and associated regulatory innovation predate the origin of Dinosauria. 
  • Finding our way through phenotypes. 
  • First Responder to Genomic Information: A Guide for Primary Care Providers. 
  • For better or worse: genomic consequences of intracellular mutualism and parasitism. 
  • Four genomic clades of Candida auris identified in Canada, 2012-2019. 
  • From breast to the brain: unraveling the puzzle of metastasis organotropism. 
  • From diagnostic testing to precision medicine: the evolving role of genomics in cardiac channelopathies and cardiomyopathies in children. 
  • From genotype to phenotype: systems biology meets natural variation. 
  • Functional Genomic Analyses of Mendelian and Sporadic Disease Identify Impaired eIF2α Signaling as a Generalizable Mechanism for Dystonia. 
  • Functional analysis of novel SNPs and mutations in human and mouse genomes. 
  • Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli. 
  • Functional genomics approach for the identification of human host factors supporting dengue viral propagation. 
  • Functional genomics identifies specific vulnerabilities in PTEN-deficient breast cancer. 
  • Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans. 
  • Functional genomics of root growth and development in Arabidopsis. 
  • Functional genomics of the beta-cell: short-chain 3-hydroxyacyl-coenzyme A dehydrogenase regulates insulin secretion independent of K+ currents. 
  • Functional interaction between responses to lactic acidosis and hypoxia regulates genomic transcriptional outputs. 
  • Functional nanostructures from surface chemistry patterning. 
  • Fungal diagnostics in pneumonia. 
  • Fungal pathogenesis: gene clusters unveiled as secrets within the Ustilago maydis code. 
  • Future translational applications from the contemporary genomics era: a scientific statement from the American Heart Association. 
  • GOBASE--a database of organelle and bacterial genome information. 
  • GREAT improves functional interpretation of cis-regulatory regions. 
  • GenBlastA: enabling BLAST to identify homologous gene sequences. 
  • Gene expression and adaptive noncoding changes during human evolution. 
  • Gene loss, adaptive evolution and the co-evolution of plumage coloration genes with opsins in birds. 
  • Generating RNA Baits for Capture-Based Enrichment. 
  • Generation of full-length cDNA libraries enriched for differentially expressed genes for functional genomics. 
  • Genetic and Genomic Analyses Reveal Boundaries between Species Closely Related to Cryptococcus Pathogens. 
  • Genetic and genomic evolution of sexual reproduction: echoes from LECA to the fungal kingdom. 
  • Genetic and pharmacological relationship between P-glycoprotein and increased cardiovascular risk associated with clarithromycin prescription: An epidemiological and genomic population-based cohort study in Scotland, UK. 
  • Genetic architecture of gene expression traits across diverse populations. 
  • Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults. 
  • Genetic dissection of the mouse CNS using magnetic resonance microscopy. 
  • Genetic effects in the leukotriene biosynthesis pathway and association with atherosclerosis. 
  • Genetic linkage study of high-grade myopia in a Hutterite population from South Dakota. 
  • Genetic markers: progress and potential for cardiovascular disease. 
  • Genetic simulation tools for post-genome wide association studies of complex diseases. 
  • Genome engineering: the next genomic revolution. 
  • Genome evolution in bacterial endosymbionts of insects. 
  • Genome-wide association studies in Africans and African Americans: expanding the framework of the genomics of human traits and disease. 
  • Genome-wide high-resolution mapping of chromosome fragile sites in Saccharomyces cerevisiae. 
  • Genome-wide identification and predictive modeling of tissue-specific alternative polyadenylation. 
  • Genome-wide mapping of DNase hypersensitive sites using massively parallel signature sequencing (MPSS). 
  • Genome-wide meta-analyses identifies novel taxane-induced peripheral neuropathy-associated loci. 
  • Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium. 
  • Genomic Amplifications and Distal 6q Loss: Novel Markers for Poor Survival in High-risk Neuroblastoma Patients. 
  • Genomic Analysis of a Hospital-Associated Outbreak of Mycobacterium abscessus: Implications on Transmission. 
  • Genomic Approaches to Posttraumatic Stress Disorder: The Psychiatric Genomic Consortium Initiative. 
  • Genomic Characterization of the Evolutionary Potential of the Sea Urchin Strongylocentrotus droebachiensis Facing Ocean Acidification. 
  • Genomic Classification and Clinical Outcome in Rhabdomyosarcoma: A Report From an International Consortium. 
  • Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer. 
  • Genomic Landscape of Cell-Free DNA in Patients with Colorectal Cancer. 
  • Genomic Medicine: 'grand challenges' in the translation of genomics to human health. 
  • Genomic Scores are Independent of Disease Volume in Men with Favorable Risk Prostate Cancer: Implications for Choosing Men for Active Surveillance. 
  • Genomic Sequencing Should Not be Part of the Standard of Care for Most Urologic Cancers. 
  • Genomic Variation across a Clinical Cryptococcus Population Linked to Disease Outcome. 
  • Genomic Views of Transcriptional Enhancers: Essential Determinants of Cellular Identity and Activity-Dependent Responses in the CNS. 
  • Genomic analyses: a neonatology perspective. 
  • Genomic analysis defines clonal relationships of ductal carcinoma in situ and recurrent invasive breast cancer. 
  • Genomic analysis demonstrates that histologically-defined astroblastomas are molecularly heterogeneous and that tumors with MN1 rearrangement exhibit the most favorable prognosis. 
  • Genomic analysis of "microphenotypes" in epilepsy. 
  • Genomic analysis of early-stage lung cancer reveals a role for TP53 mutations in distant metastasis. 
  • Genomic analysis of the origins and evolution of multicentric diffuse lower-grade gliomas. 
  • Genomic ancestry and somatic alterations correlate with age at diagnosis in Hispanic children with B-cell acute lymphoblastic leukemia. 
  • Genomic and Epigenomic Profiling of High-Risk Intestinal Metaplasia Reveals Molecular Determinants of Progression to Gastric Cancer. 
  • Genomic and Functional Approaches to Understanding Cancer Aneuploidy. 
  • Genomic and molecular profiling predicts response to temozolomide in melanoma. 
  • Genomic and outcome analysis of adult T-cell lymphoblastic lymphoma. 
  • Genomic approaches for understanding the genetics of complex disease. 
  • Genomic characterization of chronic lymphocytic leukemia (CLL) in radiation-exposed Chornobyl cleanup workers. 
  • Genomic complexity identifies patients with aggressive chronic lymphocytic leukemia. 
  • Genomic complexity is associated with epigenetic regulator mutations and poor prognosis in diffuse large B-cell lymphoma. 
  • Genomic determination of breeding systems and trans-specific evolution of HD MAT genes in suilloid fungi. 
  • Genomic dissection of conserved transcriptional regulation in intestinal epithelial cells. 
  • Genomic divergence and brain evolution: How regulatory DNA influences development of the cerebral cortex. 
  • Genomic erosion and extensive horizontal gene transfer in gut-associated Acetobacteraceae. 
  • Genomic insights into inter- and intraspecific mating system shifts in Primulina. 
  • Genomic landscape of the global oak phylogeny. 
  • Genomic map of candidate human imprint control regions: the imprintome. 
  • Genomic medicine implementation protocols in the PhenX Toolkit: tools for standardized data collection. 
  • Genomic medicine: a decade of successes, challenges, and opportunities. 
  • Genomic medicine: bringing biomarkers to clinical medicine. 
  • Genomic medicine: genetic variation and its impact on the future of health care. 
  • Genomic profiling to promote a healthy lifestyle: not ready for prime time. 
  • Genomic resources for the endangered Hawaiian honeycreepers. 
  • Genomic risk profiling: attitudes and use in personal and clinical care of primary care physicians who offer risk profiling. 
  • Genomic sequencing is required for identification of tuberculosis transmission in Hawaii. 
  • Genomic signatures of diet-related shifts during human origins. 
  • Genomic stratification for the treatment of lymphomas. 
  • Genomic translational research: Paving the way to individualized cardiac functional analyses and personalized cardiology. 
  • Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas. 
  • Genomics and clinical medicine: rationale for creating and effectively evaluating animal models. 
  • Genomics and expression profiles of the Hedgehog and Notch signaling pathways in sea urchin development. 
  • Genomics and the circulation. 
  • Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations. 
  • Genomics in medicine: a novel elective rotation for internal medicine residents. 
  • Genomics of Cardiovascular Measures of Autonomic Tone. 
  • Genomics of human health and aging. 
  • Genomics of varicose veins and chronic venous insufficiency. 
  • Genomics reveals the role of admixture in the evolution of structure among sperm whale populations within the Mediterranean Sea. 
  • Genomics, clinical research, and learning health care systems: Strategies to improve patient care. 
  • Genomics-Inspired Biomarkers and Diagnostics-Where Are They? 
  • Genomics-based identification of a potential causal role for acylcarnitine metabolism in depression. 
  • Genomics-enabled drug repositioning and repurposing: insights from an IOM Roundtable activity. 
  • Genomics. Genomics, biobanks, and the trade-secret model. 
  • Genomics: Lessons in complexity from yeast. 
  • Germline genetic landscape of pediatric central nervous system tumors. 
  • Getting to the root of plant biology: impact of the Arabidopsis genome sequence on root research. 
  • Glioma through the looking GLASS: molecular evolution of diffuse gliomas and the Glioma Longitudinal Analysis Consortium. 
  • Global approaches to genomic medicine implementation. 
  • Global transcriptome profile of Cryptococcus neoformans during exposure to hydrogen peroxide induced oxidative stress. 
  • Globally Relaxed Selection and Local Adaptation in Boechera stricta. 
  • Going the distance: Neocentromeres make long-range contacts with heterochromatin. 
  • Guidelines for Genome-Scale Analysis of Biological Rhythms. 
  • Hierarchical Convolutional Neural Networks for Segmentation of Breast Tumors in MRI With Application to Radiogenomics. 
  • High-frequency actionable pathogenic exome variants in an average-risk cohort. 
  • High-resolution genome-wide in vivo footprinting of diverse transcription factors in human cells. 
  • High-throughput interpretation of gene structure changes in human and nonhuman resequencing data, using ACE. 
  • Histone lysine methyltransferase SDG8 is involved in brassinosteroid-regulated gene expression in Arabidopsis thaliana. 
  • Histoplasmosis acquired in Alberta, Canada: an epidemiological and genomic study. 
  • How nontraditional model systems can save us. 
  • IMAGE: high-powered detection of genetic effects on DNA methylation using integrated methylation QTL mapping and allele-specific analysis. 
  • Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. 
  • Identification and characterization of a new cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody. 
  • Identification of a novel susceptibility locus for juvenile idiopathic arthritis by genome-wide association analysis. 
  • Identification of cis-suppression of human disease mutations by comparative genomics. 
  • Identification of functional elements and regulatory circuits by Drosophila modENCODE. 
  • Identifying branch-specific positive selection throughout the regulatory genome using an appropriate proxy neutral. 
  • Identifying genomic and developmental causes of adverse drug reactions in children. 
  • Identifying intragenic functional modules of genomic variations associated with cancer phenotypes by learning representation of association networks. 
  • IgA and IgG antineutrophil cytoplasmic antibody engagement of Fc receptor genetic variants influences granulomatosis with polyangiitis. 
  • Imaging Genetics and Genomics in Psychiatry: A Critical Review of Progress and Potential. 
  • Imaging genetics of brain longevity and mental wellness: the next frontier? 
  • Imaging genomics. 
  • Impact of Genomic and Clinical Factors on Outcome of Children ≥18 Months of Age with Stage 3 Neuroblastoma with Unfavorable Histology and without MYCN Amplification: A Children's Oncology Group (COG) Report. 
  • Impact of Therapy on Genomics and Transcriptomics in High-Risk Prostate Cancer Treated with Neoadjuvant Docetaxel and Androgen Deprivation Therapy. 
  • Impact of a Genomic Test on Treatment Decision in a Predominantly African American Population With Favorable-Risk Prostate Cancer: A Randomized Trial. 
  • Impact of delivery models on understanding genomic risk for type 2 diabetes. 
  • Impact of the Percepta Genomic Classifier on Clinical Management Decisions in a Multicenter Prospective Study. 
  • Implementing genomic medicine in the clinic: the future is here. 
  • Implications of the first complete human genome assembly. 
  • Improving the measurement of semantic similarity between gene ontology terms and gene products: insights from an edge- and IC-based hybrid method. 
  • Independent ancient polyploidy events in the sister families Brassicaceae and Cleomaceae. 
  • Induction of an immortalized songbird cell line allows for gene characterization and knockout by CRISPR-Cas9. 
  • Information-seeking and sharing behavior following genomic testing for diabetes risk. 
  • Initial sequencing and comparative analysis of the mouse genome. 
  • Initiation of the Primate Genome Project. 
  • Insights from a chimpanzee adipose stromal cell population: opportunities for adult stem cells to expand primate functional genomics. 
  • Insights into the evolution of social systems and species from baboon studies. 
  • Integrated Analysis of RNA and DNA from the Phase III Trial CALGB 40601 Identifies Predictors of Response to Trastuzumab-Based Neoadjuvant Chemotherapy in HER2-Positive Breast Cancer. 
  • Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types. 
  • Integrated functional networks of process, tissue, and developmental stage specific interactions in Arabidopsis thaliana. 
  • Integrated genomic analyses of ovarian carcinoma. 
  • Integrated genomic analysis of survival outliers in glioblastoma. 
  • Integrated genomic characterization of endometrial carcinoma. 
  • Integrated genomic characterization of oesophageal carcinoma. 
  • Integrated metabolomics and genomics: systems approaches to biomarkers and mechanisms of cardiovascular disease. 
  • Integrated modeling of clinical and gene expression information for personalized prediction of disease outcomes. 
  • Integrating ethics and science in the International HapMap Project. 
  • Integrating genetic and gene expression evidence into genome-wide association analysis of gene sets. 
  • Integration of functional assay data results provides strong evidence for classification of hundreds of BRCA1 variants of uncertain significance. 
  • Integrative Genomics Identifies Novel Associations with APOL1 Risk Genotypes in Black NEPTUNE Subjects. 
  • Integrative Omics: Harnessing the Proteome to Maximize the Potential of the Genome. 
  • Integrative annotation of variants from 1092 humans: application to cancer genomics. 
  • Integrative biomechanics: A paradigm for clinical applications of fundamental mechanics 
  • Integrative genomic approaches identify IKBKE as a breast cancer oncogene. 
  • Integrative genomic approaches to understanding cancer. 
  • Integrative genomics identifies RAB23 as an invasion mediator gene in diffuse-type gastric cancer. 
  • Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease. 
  • Integrative metabolomics-genomics approach reveals key metabolic pathways and regulators of Alzheimer's disease. 
  • Integrative systems biology: an attempt to describe a simple weed. 
  • Interdisciplinary Models for Research and Clinical Endeavors in Genomic Medicine: A Scientific Statement From the American Heart Association. 
  • Interpretation and reporting of large regions of homozygosity and suspected consanguinity/uniparental disomy, 2021 revision: A technical standard of the American College of Medical Genetics and Genomics (ACMG). 
  • Interpreting the genomic landscape of speciation: a road map for finding barriers to gene flow. 
  • Knowledge about genomic recurrence risk testing among breast cancer survivors. 
  • Label propagation defines signaling networks associated with recurrently mutated cancer genes. 
  • Laboratory analysis of acylcarnitines, 2020 update: a technical standard of the American College of Medical Genetics and Genomics (ACMG). 
  • Laboratory analysis of amino acids, 2018 revision: a technical standard of the American College of Medical Genetics and Genomics (ACMG). 
  • Laboratory diagnosis of creatine deficiency syndromes: a technical standard and guideline of the American College of Medical Genetics and Genomics. 
  • Large-scale genetic investigation reveals genetic liability to multiple complex traits influencing a higher risk of ADHD. 
  • Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. 
  • Letter to the editor: Standardization of genetic association studies, pros and cons, reaffirmed. 
  • Letting the genome out of the bottle. 
  • Leveraging Genome and Phenome-Wide Association Studies to Investigate Genetic Risk of Acute Lymphoblastic Leukemia. 
  • Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium. 
  • Linking Genes to Cardiovascular Diseases: Gene Action and Gene-Environment Interactions. 
  • Linking Genes to Molecules in Eukaryotic Sources: An Endeavor to Expand Our Biosynthetic Repertoire. 
  • Liver genomic responses to ciguatoxin: evidence for activation of phase I and phase II detoxification pathways following an acute hypothermic response in mice. 
  • Localizing Post-Admixture Adaptive Variants with Object Detection on Ancestry-Painted Chromosomes. 
  • Making Personalized Health Care Even More Personalized: Insights From Activities of the IOM Genomics Roundtable. 
  • Managing incidental genomic findings: legal obligations of clinicians. 
  • Manifestations of Alzheimer's disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90. 
  • Mapping genomic loci implicates genes and synaptic biology in schizophrenia. 
  • Mapping nucleosome positions using DNase-seq. 
  • Mapping the proteo-genomic convergence of human diseases. 
  • Medical genomics: Gather and use genetic data in health care. 
  • Medulloblastoma Down Under 2013: a report from the third annual meeting of the International Medulloblastoma Working Group. 
  • Merfin: improved variant filtering, assembly evaluation and polishing via k-mer validation. 
  • Merging Electronic Health Record Data and Genomics for Cardiovascular Research: A Science Advisory From the American Heart Association. 
  • Mesenchymal stem cells use integrin beta1 not CXC chemokine receptor 4 for myocardial migration and engraftment. 
  • Metabolomics applied to diabetes research: moving from information to knowledge. 
  • Methionine metabolism influences genomic architecture and gene expression through H3K4me3 peak width. 
  • Mining the Gene Wiki for functional genomic knowledge. 
  • Molecular Biology and Evolution of Cancer: From Discovery to Action. 
  • Molecular Imaging and Precision Medicine in Head and Neck Cancer. 
  • Molecular Tools for Carotenogenesis Analysis in the Mucoral Mucor circinelloides. 
  • Molecular and genetic markers in thoracic surgery. 
  • Molecular biomarkers in glaucoma. 
  • Molecular medicine tumor board: whole-genome sequencing to inform on personalized medicine for a man with advanced prostate cancer. 
  • Molecular pathology of prostate cancer revealed by next-generation sequencing: opportunities for genome-based personalized therapy. 
  • Morning glory as a powerful model in ecological genomics: tracing adaptation through both natural and artificial selection. 
  • Moving away from one disease at a time: Screening, trial design, and regulatory implications of novel platform technologies. 
  • Multi-marker strategies in heart failure: clinical and statistical approaches. 
  • Multi-omics integration in biomedical research - A metabolomics-centric review. 
  • Multicenter study of acetaminophen hepatotoxicity reveals the importance of biological endpoints in genomic analyses. 
  • Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function. 
  • Multilocus patterns of nucleotide diversity, population structure and linkage disequilibrium in Boechera stricta, a wild relative of Arabidopsis. 
  • Multiple regions within 8q24 independently affect risk for prostate cancer. 
  • Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility. 
  • Multiregional Radiogenomic Assessment of Prostate Microenvironments with Multiparametric MR Imaging and DNA Whole-Exome Sequencing of Prostate Glands with Adenocarcinoma. 
  • NEIBank: genomics and bioinformatics resources for vision research. 
  • Neptune: an environment for the delivery of genomic medicine. 
  • Network-assisted genetic dissection of pathogenicity and drug resistance in the opportunistic human pathogenic fungus Cryptococcus neoformans. 
  • New insights into gestational glucose metabolism: lessons learned from 21st century approaches. 
  • New paradigms in cardiovascular medicine: emerging technologies and practices: perioperative genomics. 
  • Next-Generation Sequencing Concordance Analysis of Comprehensive Solid Tumor Profiling between a Centralized Specialty Laboratory and the Decentralized Personal Genome Diagnostics elio Tissue Complete Kitted Solution. 
  • Next-generation sequencing for constitutional variants in the clinical laboratory, 2021 revision: a technical standard of the American College of Medical Genetics and Genomics (ACMG). 
  • Non-canonical genomic driver mutations of urethane carcinogenesis. 
  • Obesity Genomics and Metabolomics: a Nexus of Cardiometabolic Risk. 
  • Omics approaches to discover pathophysiological pathways contributing to human pain. 
  • Omics meet networks - using systems approaches to infer regulatory networks in plants. 
  • Only connect: personal genomics and the future of American medicine. 
  • Open Chromatin Profiling in Adipose Tissue Marks Genomic Regions with Functional Roles in Cardiometabolic Traits. 
  • Open window: when easily identifiable genomes and traits are in the public domain. 
  • Operationalizing Precision Cardiovascular Medicine: Three Innovations. 
  • Opportunities to implement a sustainable genomic medicine program: lessons learned from the IGNITE Network. 
  • Opportunities, resources, and techniques for implementing genomics in clinical care. 
  • Opportunities-and hard work-ahead. 
  • Organellar phylogenomics of an emerging model system: Sphagnum (peatmoss). 
  • Organizational improvements to enhance modern clinical epidemiology. 
  • Origins of MERS-CoV, and lessons for 2019-nCoV. 
  • OrthoClusterDB: an online platform for synteny blocks. 
  • Outcome of Whole Exome Sequencing for Diagnostic Odyssey Cases of an Individualized Medicine Clinic: The Mayo Clinic Experience. 
  • PBmice: an integrated database system of piggyBac (PB) insertional mutations and their characterizations in mice. 
  • PROMISE: a real-world clinical-genomic database to address knowledge gaps in prostate cancer. 
  • Palo: spatially aware color palette optimization for single-cell and spatial data. 
  • Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas. 
  • Pan-cancer analysis of whole genomes. 
  • Parallel Multi-Omics in High-Risk Subjects for the Identification of Integrated Biomarker Signatures of Type 1 Diabetes. 
  • Parallel assay of oxygen equilibria of hemoglobin. 
  • Partial shotgun sequencing of the Boechera stricta genome reveals extensive microsynteny and promoter conservation with Arabidopsis. 
  • Participant choices for return of genomic results in the eMERGE Network. 
  • Pathogenesis of varicose veins. 
  • Pathophysiology of the blood-brain barrier: animal models and methods. 
  • Patterns of somatic mutation in human cancer genomes. 
  • Performance assessment of promoter predictions on ENCODE regions in the EGASP experiment. 
  • Performance of repeat cytology with reflex ThyroSeq genomic classifier for indeterminant thyroid cytology. 
  • Personalized Prediction Model to Risk Stratify Patients With Myelodysplastic Syndromes. 
  • Personalized health care in 2013: a status report on the impact of genomics. 
  • Personalized health care: from theory to practice. 
  • Personalized targeted therapy for esophageal squamous cell carcinoma. 
  • Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics. 
  • Perspective: Prospective health care and the role of academic medicine: lead, follow, or get out of the way. 
  • Perspectives from the Avian Phylogenomics Project: Questions that Can Be Answered with Sequencing All Genomes of a Vertebrate Class. 
  • Pharmacogenomics and end-organ susceptibility to injury in the perioperative period. 
  • Pharmacogenomics study of thiazide diuretics and QT interval in multi-ethnic populations: the cohorts for heart and aging research in genomic epidemiology. 
  • Pharmacometabolomics reveals racial differences in response to atenolol treatment. 
  • PhenoDis: a comprehensive database for phenotypic characterization of rare cardiac diseases. 
  • PhyloOncology: Understanding cancer through phylogenetic analysis. 
  • Phylogenetic and Phylogenomic Definition of Rhizopus Species. 
  • Phylogenetic, genomic, and biogeographic characterization of a novel and ubiquitous marine invertebrate-associated Rickettsiales parasite, Candidatus Aquarickettsia rohweri, gen. nov., sp. nov. 
  • Phylogenomic analyses data of the avian phylogenomics project. 
  • Phylogenomic analyses provide insights into primate evolution. 
  • Phylogeny and evolution of aldehyde dehydrogenase-homologous folate enzymes. 
  • Phylogeography's past, present, and future: 10 years after Avise, 2000. 
  • Physiological Genomics: Who we are and where we're going. 
  • Physiological genomics of cardiac disease: quantitative relationships between gene expression and left ventricular hypertrophy. 
  • Physiological genomics of human arteries: quantitative relationship between gene expression and arterial stiffness. 
  • Pioneering geneticist Mary-Claire King receives the 2014 Lasker~Koshland Special Achievement Award in Medical Science. 
  • Platelets from genome to proteome and beyond. 
  • Plug-and-Play Protein Modification Using Homology-Independent Universal Genome Engineering. 
  • Points to consider in the reevaluation and reanalysis of genomic test results: a statement of the American College of Medical Genetics and Genomics (ACMG). 
  • Polymorphisms and evolutionary history of retrotransposon insertions in rice promoters. 
  • Population perspectives on functional genomic variation in yeast. 
  • Population-genomic inference of the strength and timing of selection against gene flow. 
  • Positive selection in noncoding genomic regions of vocal learning birds is associated with genes implicated in vocal learning and speech functions in humans. 
  • Posttranslational, translational, and transcriptional responses to nitric oxide stress in Cryptococcus neoformans: implications for virulence. 
  • Preanalytical Variables for the Genomic Assessment of the Cellular and Acellular Fractions of the Liquid Biopsy in a Cohort of Breast Cancer Patients. 
  • Precision Medicine: From Science To Value. 
  • Predicting clinical outcome of therapy-resistant prostate cancer. 
  • Prediction of a time-to-event trait using genome wide SNP data. 
  • Preface to the special issue: ecological and evolutionary genomics of populations in nature. 
  • Primary role for endoplasmic reticulum-bound ribosomes in cellular translation identified by ribosome profiling. 
  • Prognostic modeling in early stage lung cancer: an evolving process from histopathology to genomics. 
  • Progressive Cactus is a multiple-genome aligner for the thousand-genome era. 
  • Prospective care: a personalized, preventative approach to medicine. 
  • Prospective health care: the second transformation of medicine. 
  • Prospective medicine: the role for genomics in personalized health planning. 
  • Prospects for personalized cardiovascular medicine: the impact of genomics. 
  • Proteomic profiling of patient-derived glioblastoma xenografts identifies a subset with activated EGFR: implications for drug development. 
  • PseudoBase: a genomic visualization and exploration resource for the Drosophila pseudoobscura subgroup. 
  • Psychiatric disease in the genomic era: rational approach. 
  • Public health. Genomics and medicine at a crossroads in Chernobyl. 
  • Public knowledge of and attitudes toward genetics and genetic testing. 
  • Public perspectives on returning genetics and genomics research results. 
  • Public perspectives regarding data-sharing practices in genomics research. 
  • Purine synthesis promotes maintenance of brain tumor initiating cells in glioma. 
  • QBiC-Pred: quantitative predictions of transcription factor binding changes due to sequence variants. 
  • Qualitative study of system-level factors related to genomic implementation. 
  • Quantum computing at the frontiers of biological sciences. 
  • Radiogenomic analysis of breast cancer: luminal B molecular subtype is associated with enhancement dynamics at MR imaging. 
  • Radiogenomics: what it is and why it is important. 
  • Randomized trial of personal genomics for preventive cardiology: design and challenges. 
  • Real-Time Genomic Profiling of Pancreatic Ductal Adenocarcinoma: Potential Actionability and Correlation with Clinical Phenotype. 
  • Realising the Value of Linked Data to Health Economic Analyses of Cancer Care: A Case Study of Cancer 2015. 
  • Realizing the Full Potential of Precision Medicine in Health and Health Care. 
  • Realizing the opportunities of genomics in health care. 
  • Reclassification of cardiovascular risk using integrated clinical and molecular biosignatures: Design of and rationale for the Measurement to Understand the Reclassification of Disease of Cabarrus and Kannapolis (MURDOCK) Horizon 1 Cardiovascular Disease Study. 
  • Reconstruction of gross avian genome structure, organization and evolution suggests that the chicken lineage most closely resembles the dinosaur avian ancestor. 
  • Redefining Genomic Privacy: Trust and Empowerment 
  • Redefining heart failure: the utility of genomics. 
  • Regeneration Genetics. 
  • Regulation: The FDA is Overcautious on Consumer Genetics 
  • Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii. 
  • Relative contribution of clinicopathological variables, genomic markers, transcriptomic subtyping and microenvironment features for outcome prediction in stage II/III colorectal cancer. 
  • Replicated Landscape Genomics Identifies Evidence of Local Adaptation to Urbanization in Wood Frogs. 
  • Reply to A. Dalla Volta et al. 
  • Report on the 6th African Society of Human Genetics (AfSHG) Meeting, March 12-15, 2009, Yaounde, Cameroon. 
  • Research capacity. Enabling the genomic revolution in Africa. 
  • Residual dipolar couplings: synergy between NMR and structural genomics. 
  • Response to Rosenberg et al. 
  • Returning integrated genomic risk and clinical recommendations: The eMERGE study. 
  • Revolution and renaissance. 
  • Robust regression analysis of copy number variation data based on a univariate score. 
  • Role of natural product diversity in chemical biology. 
  • SMARCA4 and Other SWItch/Sucrose NonFermentable Family Genomic Alterations in NSCLC: Clinicopathologic Characteristics and Outcomes to Immune Checkpoint Inhibition. 
  • SMRT Sequencing for Parallel Analysis of Multiple Targets and Accurate SNP Phasing. 
  • SNiPA: an interactive, genetic variant-centered annotation browser. 
  • Sacrifice, individuation, and the economies of genomics. 
  • Sample type bias in the analysis of cancer genomes. 
  • Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines. 
  • Searching for genes that matter in acute kidney injury: a systematic review. 
  • Secrets of the perioptome: new tools for a new concept. 
  • Selection of optimal reference genes for normalization in quantitative RT-PCR. 
  • Semi-automated assembly of high-quality diploid human reference genomes. 
  • Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program. 
  • Showcasing Fungal Genetics & Genomics with the Genetics Society of America. 
  • SigProfilerMatrixGenerator: a tool for visualizing and exploring patterns of small mutational events. 
  • Signatures of neutral evolution in exponentially growing tumors: A theoretical perspective. 
  • Single-cell genomics identifies cell type-specific molecular changes in autism. 
  • Single-cell genomics revolutionizes plant development studies across scales. 
  • Six reference-quality genomes reveal evolution of bat adaptations. 
  • Small but Mighty: Functional Peptides Encoded by Small ORFs in Plants. 
  • Speciation genetics: evolving approaches. 
  • Sphagnum physiology in the context of changing climate: emergent influences of genomics, modelling and host-microbiome interactions on understanding ecosystem function. 
  • Sphingolipid Metabolic Pathway Impacts Thiazide Diuretics Blood Pressure Response: Insights From Genomics, Metabolomics, and Lipidomics. 
  • Standards recommendations for the Earth BioGenome Project. 
  • Statistical Viewer: a tool to upload and integrate linkage and association data as plots displayed within the Ensembl genome browser. 
  • Statistical challenges in preprocessing in microarray experiments in cancer. 
  • Strengthening the reporting of Genetic RIsk Prediction Studies (GRIPS): explanation and elaboration. 
  • Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration. 
  • Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration. 
  • Stringent comparative sequence analysis reveals SOX10 as a putative inhibitor of glial cell differentiation. 
  • Structural and transcriptional analyses of a purine nucleotide-binding protein from Pyrococcus furiosus: a component of a novel, membrane-bound multiprotein complex unique to this hyperthermophilic archaeon. 
  • Structural genomics of Pyrococcus furiosus: X-ray crystallography reveals 3D domain swapping in rubrerythrin. 
  • Subgroup-specific structural variation across 1,000 medulloblastoma genomes. 
  • Summary of the OA biomarkers workshop 2010 - genetics and genomics: new targets in OA. 
  • Suppression of ABHD2, identified through a functional genomics screen, causes anoikis resistance, chemoresistance and poor prognosis in ovarian cancer. 
  • Synthetic lethal analysis of Caenorhabditis elegans posterior embryonic patterning genes identifies conserved genetic interactions. 
  • Systems Genetics for Mechanistic Discovery in Heart Diseases. 
  • TBestDB: a taxonomically broad database of expressed sequence tags (ESTs). 
  • Taking the first steps towards a standard for reporting on phylogenies: Minimum Information About a Phylogenetic Analysis (MIAPA). 
  • Test-Retest Reliability of the Genetics and Genomics in Nursing Practice Survey Instrument. 
  • The 17-Gene Genomic Prostate Score Test Is Prognostic for Outcomes After Primary External Beam Radiation Therapy in Men With Clinically Localized Prostate Cancer. 
  • The ABC's of comparative genomics in the Brassicaceae: building blocks of crucifer genomes. 
  • The Bioinformatics Open Source Conference (BOSC) 2013. 
  • The DNA sequence and biological annotation of human chromosome 1. 
  • The DNA sequence of the human X chromosome. 
  • The ENCODE (ENCyclopedia Of DNA Elements) Project. 
  • The Earth BioGenome Project 2020: Starting the clock. 
  • The Gene Ontology (GO) database and informatics resource. 
  • The Gene Ontology in 2010: extensions and refinements. 
  • The Gene Ontology project in 2008. 
  • The Genome 10K Project: a way forward. 
  • The Genomic Medicine Integrative Research Framework: A Conceptual Framework for Conducting Genomic Medicine Research. 
  • The Genomics Research and Innovation Network: creating an interoperable, federated, genomics learning system. 
  • The Global Synanthrome Project: A Call for an Exhaustive Study of Human Associates. 
  • The Human Pangenome Project: a global resource to map genomic diversity. 
  • The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution. 
  • The IGNITE network: a model for genomic medicine implementation and research. 
  • The Immune Landscape of Cancer. 
  • The International HapMap Project. 
  • The MetJ regulon in gammaproteobacteria determined by comparative genomics methods. 
  • The NEXT-1 (Next generation pErsonalized tX with mulTi-omics and preclinical model) trial: prospective molecular screening trial of metastatic solid cancer patients, a feasibility analysis. 
  • The National Academies' Roundtable on Genomics and Precision Health: Where we have been and where we are heading. 
  • The Psychiatric Genomics Consortium Posttraumatic Stress Disorder Workgroup: Posttraumatic Stress Disorder Enters the Age of Large-Scale Genomic Collaboration. 
  • The SSV Evaluation System: A Tool to Prioritize Short Structural Variants for Studies of Possible Regulatory and Causal Variants. 
  • The Scientific Foundation for personal genomics: recommendations from a National Institutes of Health-Centers for Disease Control and Prevention multidisciplinary workshop. 
  • The Sphagnome Project: enabling ecological and evolutionary insights through a genus-level sequencing project. 
  • The Trait Repertoire Enabling Cyanobacteria to Bloom Assessed through Comparative Genomic Complexity and Metatranscriptomics. 
  • The accessible chromatin landscape of the human genome. 
  • The case for strategic international alliances to harness nutritional genomics for public and personal health. 
  • The comparative genomics and complex population history of Papio baboons. 
  • The dangers of diagnostic monopolies. 
  • The designated record set for clinical genetic and genomic testing: A points to consider statement of the American College of Medical Genetics and Genomics (ACMG). 
  • The discovery of microdeletion syndromes in the post-genomic era: review of the methodology and characterization of a new 1q41q42 microdeletion syndrome. 
  • The ecological, genetic and genomic architecture of local adaptation and population differentiation in Boechera stricta . 
  • The enduring importance of family health history in the era of genomic medicine and risk assessment. 
  • The era of reference genomes in conservation genomics. 
  • The future of Physiological Genomics. 
  • The genetic landscape of gliomas arising after therapeutic radiation. 
  • The genome of the green anole lizard and a comparative analysis with birds and mammals. 
  • The genomic analysis of erythrocyte microRNA expression in sickle cell diseases. 
  • The genomic analysis of lactic acidosis and acidosis response in human cancers. 
  • The genomic epidemiology of multi-drug resistant invasive non-typhoidal Salmonella in selected sub-Saharan African countries. 
  • The genomic landscape of TERT promoter wildtype-IDH wildtype glioblastoma. 
  • The genomic landscape of familial glioma. 
  • The genomic landscape of mantle cell lymphoma is related to the epigenetically determined chromatin state of normal B cells. 
  • The genomic, biochemical, and cellular responses of the retina in inherited photoreceptor degenerations and prospects for the treatment of these disorders. 
  • The genomics education partnership: successful integration of research into laboratory classes at a diverse group of undergraduate institutions. 
  • The genomics of speciation in Drosophila: diversity, divergence, and introgression estimated using low-coverage genome sequencing. 
  • The host response as a tool for infectious disease diagnosis and management. 
  • The impact of disregarding family structure on genome-wide association analysis of complex diseases in cohorts with simple pedigrees. 
  • The impact of genomics on the biotechnology industry. 
  • The integrated genomic and epigenomic landscape of brainstem glioma. 
  • The integrated landscape of driver genomic alterations in glioblastoma. 
  • The integration of molecular diagnostics with therapeutics. Implications for drug development and pathology practice. 
  • The lemur revolution starts now: the genomic coming of age for a non-model organism. 
  • The naturalist in a world of genomics. 
  • The new age of medical genomics. 
  • The origin of extracellular DNA during the clearance of dead and dying cells. 
  • The performance of ZDOCK and ZRANK in rounds 6-11 of CAPRI. 
  • The rise of genomic profiling in ovarian cancer. 
  • The routinisation of genomics and genetics: implications for ethical practices. 
  • The teleost anatomy ontology: anatomical representation for the genomics age. 
  • The value of population-based studies in the genomic era. 
  • The virulence of human pathogenic fungi: notes from the South of France. 
  • The whole-genome landscape of medulloblastoma subtypes. 
  • These Are the Genes You're Looking For: Finding Host Resistance Genes. 
  • Thousands of small, novel genes predicted in global phage genomes. 
  • Toward clinical genomics in everyday medicine: perspectives and recommendations. 
  • Towards integrated clinico-genomic models for personalized medicine: combining gene expression signatures and clinical factors in breast cancer outcomes prediction. 
  • Towards structural genomics of RNA: rapid NMR resonance assignment and simultaneous RNA tertiary structure determination using residual dipolar couplings. 
  • Transcriptome analysis reveals novel patterning and pigmentation genes underlying Heliconius butterfly wing pattern variation. 
  • Translating genomic biomarkers into clinically useful diagnostics. 
  • Translating genomics into clinical practice: applications in lung cancer. 
  • Translating the genomics revolution: the need for an international gene therapy consortium for monogenic diseases. 
  • Translational Bioinformatics: Past, Present, and Future. 
  • Uncoupling of genomic and epigenetic signals in the maintenance and inheritance of heterochromatin domains in fission yeast. 
  • Uncovering the HARbingers of human brain evolution. 
  • Uncovering the genomic signature of ancient introgression between white oak lineages (Quercus). 
  • Understanding Mucor circinelloides pathogenesis by comparative genomics and phenotypical studies. 
  • Understanding the biological basis of psychiatric disease: What's next? 
  • Unisexual reproduction drives meiotic recombination and phenotypic and karyotypic plasticity in Cryptococcus neoformans. 
  • Unlocking the secrets of the genome. 
  • Unraveling the dynamic transcriptome. 
  • Update on Chronic Kidney Disease Mineral and Bone Disorder in Cardiovascular Disease. 
  • Update on the genetics of primary open-angle glaucoma. 
  • Updates and Critical Evaluation on Novel Biomarkers for the Malignant Progression of Intraductal Papillary Mucinous Neoplasms of the Pancreas. 
  • Urine as a high-quality source of host genomic DNA from wild populations. 
  • Use of integrative epigenetic and cytogenetic analyses to identify novel tumor-suppressor genes in malignant melanoma. 
  • Using context to improve protein domain identification. 
  • Validation of a genomic classifier for prediction of metastasis and prostate cancer-specific mortality in African-American men following radical prostatectomy in an equal access healthcare setting. 
  • Very low mutation burden is a feature of inflamed recurrent glioblastomas responsive to cancer immunotherapy. 
  • Visual annotation of the gene database. 
  • We are the genes we've been waiting for: rational responses to the gathering storm of personal genomics. 
  • What can patterns of differentiation across plant genomes tell us about adaptation and speciation? 
  • What can you do with 0.1x genome coverage? A case study based on a genome survey of the scuttle fly Megaselia scalaris (Phoridae). 
  • What was old is new again: using the host response to diagnose infectious disease. 
  • What will it take to implement genomics in practice? Lessons from the IGNITE Network. 
  • Who owns the genome? 
  • Whole Genomic Copy Number Alterations in Circulating Tumor Cells from Men with Abiraterone or Enzalutamide-Resistant Metastatic Castration-Resistant Prostate Cancer. 
  • Whole blood gene expression analyses in patients with single versus recurrent venous thromboembolism. 
  • Whole-Genome Analysis Illustrates Global Clonal Population Structure of the Ubiquitous Dermatophyte Pathogen Trichophyton rubrum. 
  • Whole-Slide Cytometric Feature Mapping for Distinguishing Tumor Genomic Subtypes in Head and Neck Squamous Cell Carcinoma Whole-Slide Images. 
  • Whole-exome sequencing in undiagnosed genetic diseases: interpreting 119 trios. 
  • Whole-genome reconstruction and mutational signatures in gastric cancer. 
  • Why sequence all eukaryotes? 
  • Widespread false gene gains caused by duplication errors in genome assemblies. 
  • YbiV from Escherichia coli K12 is a HAD phosphatase. 
  • cnvCapSeq: detecting copy number variation in long-range targeted resequencing data. 
  • dictyBase, the model organism database for Dictyostelium discoideum. 
  • dictyBase--a Dictyostelium bioinformatics resource update. 
  • dictyBase: a new Dictyostelium discoideum genome database. 
  • minotaur: A platform for the analysis and visualization of multivariate results from genome scans with R Shiny. 
  • siRNA-based approaches in cancer therapy. 
• 

  Keywords of People

  • Acharya, Chaitanya, Research Associate, Senior, Surgery
  • Baugh, L. Ryan, Associate Professor of Biology, Biology
  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Cho, Alex Han, Associate Professor of Medicine, Medicine, General Internal Medicine
  • Guevara, Elaine Elizabeth Gomez, Lecturer in Evolutionary Anthropology, Evolutionary Anthropology
  • Haase, Steven B., Professor of Biology, Biology
  • Hartemink, Alexander J., Professor in the Department of Computer Science, Biology
  • Ji, Zhicheng, Assistant Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics
  • Knisely, Mitchell, Associate Professor in the School of Nursing, School of Nursing
  • Landstrom, Andrew Paul, Associate Professor of Pediatrics, Cell Biology
  • Liu, Yongmei, Professor of Medicine, Medicine, Cardiology
  • Magwene, Paul Mitaari, Professor of Biology, Biology
  • Mangan, Riley, Student, Basic Science Departments
  • McLendon, Roger Edwin, Professor of Pathology, Pathology
  • Mitchell-Olds, Thomas, Newman Ivey White Distinguished Professor of Biology, Biology
  • O'Connor, Christopher Michael, Adjunct Professor in the Department of Medicine, Medicine, Clinical Pharmacology
  • Orlando, Lori Ann, Professor of Medicine, Medicine, General Internal Medicine
  • Osterberg, Joshua Samuel, Adjunct Assistant Professor in the Marine Science and Conservation Division, Marine Science and Conservation
  • Patel, Uptal Dinesh, Adjunct Professor in the Department of Medicine, Medicine, Nephrology
  • Reddy, Timothy E, Associate Professor of Biostatistics & Bioinformatics,, Molecular Genetics and Microbiology
  • Reitman, Zachary James, Assistant Professor of Radiation Oncology, Pathology
  • Swain Lenz, Devi, Research Scientist, Biology
  • Tsalik, Ephraim, Adjunct Associate Professor in the Department of Medicine, Medicine, Infectious Diseases
  • Wald, Priscilla, R. Florence Brinkley Distinguished Professor of English, Duke Science & Society
  • Wernegreen, Jennifer Jo, Lee Hill Snowdon Associate Professor, Environmental Sciences and Policy
  • Wray, Gregory Allan, Professor of Biology, Evolutionary Anthropology
  • Yoder, Anne Daphne, Braxton Craven Distinguished Professor of Evolutionary Biology, Duke Science & Society