Genomics

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  Subject Areas on Research

  • A Guide for a Cardiovascular Genomics Biorepository: the CATHGEN Experience. 
  • A central support system can facilitate implementation and sustainability of a Classroom-based Undergraduate Research Experience (CURE) in Genomics. 
  • A course-based research experience: how benefits change with increased investment in instructional time. 
  • A general integrative genomic feature transcription factor binding site prediction method applied to analysis of USF1 binding in cardiovascular disease. 
  • A genomic approach to colon cancer risk stratification yields biologic insights into therapeutic opportunities. 
  • A genomic approach to identify molecular pathways associated with chemotherapy resistance. 
  • A genomic approach to identify regulatory nodes in the transcriptional network of systemic acquired resistance in plants. 
  • A genomic approach to improve prognosis and predict therapeutic response in chronic lymphocytic leukemia. 
  • A genomic strategy to elucidate modules of oncogenic pathway signaling networks. 
  • A genomic- and proteomic-based hypothesis on the eclectic effects of systemic interleukin-2 administration in the context of melanoma-specific immunization. 
  • A global approach to tumor immunology. 
  • A global reference for human genetic variation. 
  • A health services research agenda for cellular, molecular and genomic technologies in cancer care. 
  • A high-density screen for linkage in multiple sclerosis. 
  • A hybrid bayesian approach for genome-wide association studies on related individuals. 
  • A joint analysis of metabolomics and genetics of breast cancer. 
  • A knowledge network for a dynamic taxonomy of psychiatric disease. 
  • A national clinical decision support infrastructure to enable the widespread and consistent practice of genomic and personalized medicine. 
  • A novel integrative risk index of papillary thyroid cancer progression combining genomic alterations and clinical factors. 
  • A pathway-based classification of human breast cancer. 
  • A personalized paradigm in the treatment of platinum-resistant ovarian cancer - A cost utility analysis of genomic-based versus cytotoxic therapy. 
  • Abundant raw material for cis-regulatory evolution in humans. 
  • Academic-industrial partnerships in drug discovery in the age of genomics. 
  • Advancing toxicology research using in vivo high throughput toxicology with small fish models. 
  • Allelic variations in gene expression. 
  • American College of Medical Genetics and Genomics: standards and guidelines for documenting suspected consanguinity as an incidental finding of genomic testing. 
  • An Exploration into Fern Genome Space. 
  • An evaluation of copy number variation detection tools from whole-exome sequencing data. 
  • An integrated encyclopedia of DNA elements in the human genome. 
  • An integrated genomic-based approach to individualized treatment of patients with advanced-stage ovarian cancer. 
  • An integrated map of genetic variation from 1,092 human genomes. 
  • An overview of genomic data analysis. 
  • Analysing breast cancer microarrays from African Americans using shrinkage-based discriminant analysis. 
  • Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. 
  • Are all horizontal gene transfers created equal? Prospects for mechanism-based studies of HGT patterns. 
  • Assessing bioequivalence using genomic data. 
  • Assessing the utility of thermodynamic features for microRNA target prediction under relaxed seed and no conservation requirements. 
  • Assessing the utility of whole genome amplified DNA for next-generation molecular ecology. 
  • Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans. 
  • Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. 
  • Author's Reply. 
  • Author’s response: Humans, fruit flies, and automatons. 
  • Avian genomes. A flock of genomes. Introduction. 
  • Avianbase: a community resource for bird genomics. 
  • Basic concepts and potential applications of genetics and genomics for cardiovascular and stroke clinicians: a scientific statement from the American Heart Association. 
  • Bayesian consensus clustering. 
  • Bayesian joint analysis of heterogeneous genomics data. 
  • Bayesian quantitative electrophysiology and its multiple applications in bioengineering. 
  • Behavior genetics and postgenomics. 
  • Biomarkers for amyotrophic lateral sclerosis. 
  • Blood and stories: how genomics is rewriting race, medicine and human history 
  • Boechera, a model system for ecological genomics. 
  • Building the evidence base for decision making in cancer genomic medicine using comparative effectiveness research. 
  • COUGER--co-factors associated with uniquely-bound genomic regions. 
  • Cancer systems biology: exploring cancer-associated genes on cellular networks. 
  • Cardiac function and heart failure. 
  • Cell cycle-regulated transcription: effectively using a genomics toolbox. 
  • ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia. 
  • Chiropteran types I and II interferon genes inferred from genome sequencing traces by a statistical gene-family assembler. 
  • Clinical Applications of the Genomic Landscape of Aggressive Non-Hodgkin Lymphoma. 
  • Combinatorial Mismatch Scan (CMS) for loci associated with dementia in the Amish. 
  • Common genetic variation and human traits. 
  • Comparative effectiveness research in cancer genomics and precision medicine: current landscape and future prospects. 
  • Comparative effectiveness research, genomics-enabled personalized medicine, and rapid learning health care: a common bond. 
  • Comparative genome-wide screening identifies a conserved doxorubicin repair network that is diploid specific in Saccharomyces cerevisiae. 
  • Comparative genomic analysis of fungal genomes reveals intron-rich ancestors. 
  • Comparative genomics and regulatory evolution: conservation and function of the Chs and Apetala3 promoters. 
  • Comparative genomics as a tool for gene discovery. 
  • Comparative genomics in the Brassicaceae: a family-wide perspective. 
  • Comparative genomics of mammalian hibernators using gene networks. 
  • Comparative genomics reveals insights into avian genome evolution and adaptation. 
  • Comparative genomics reveals molecular features unique to the songbird lineage. 
  • Comparison of genomics and functional imaging from canine sarcomas treated with thermoradiotherapy predicts therapeutic response and identifies combination therapeutics. 
  • Computational approach to radiogenomics of breast cancer: Luminal A and luminal B molecular subtypes are associated with imaging features on routine breast MRI extracted using computer vision algorithms. 
  • Contrasts between adaptive coding and noncoding changes during human evolution. 
  • Copy number variation contributes to cryptic genetic variation in outbreak lineages of Cryptococcus gattii from the North American Pacific Northwest. 
  • Cross species genomic analysis identifies a mouse model as undifferentiated pleomorphic sarcoma/malignant fibrous histiocytoma. 
  • Cross-study projections of genomic biomarkers: an evaluation in cancer genomics. 
  • Cross-validation for linear model with unequal variances in genomic analysis. 
  • DNA patents and diagnostics: not a pretty picture. 
  • DNase-seq predicts regions of rotational nucleosome stability across diverse human cell types. 
  • DSSTox chemical-index files for exposure-related experiments in ArrayExpress and Gene Expression Omnibus: enabling toxico-chemogenomics data linkages. 
  • Deciding among green plants for whole genome studies. 
  • Defending information-free genocentrism. 
  • Defining the balance of risk and benefit in the era of genomics and proteomics. 
  • Design and implementation of high-throughput RNAi screens in cultured Drosophila cells. 
  • Design, Assembly, and Characterization of TALE-Based Transcriptional Activators and Repressors. 
  • Detailed assessment of chromosome 22 aberrations in sporadic pheochromocytoma using array-CGH. 
  • Development and application of a phylogenomic toolkit: resolving the evolutionary history of Madagascar's lemurs. 
  • Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome. 
  • Drosophila genome-wide RNAi screens: are they delivering the promise? 
  • Drosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution. 
  • Ecological genomics of Boechera stricta: identification of a QTL controlling the allocation of methionine- vs branched-chain amino acid-derived glucosinolates and levels of insect herbivory. 
  • Educating future providers of personalized medicine. 
  • Embracing the complexity of genomic data for personalized medicine. 
  • Enabling functional genomics with genome engineering. 
  • Ensuring the safe use of genomic medicine in children. 
  • Environmental genomics: a key to understanding biology, pathophysiology and disease. 
  • Estimating genomic coexpression networks using first-order conditional independence. 
  • Evidence for a single loss of mineralized teeth in the common avian ancestor. 
  • Evolution of genes and genomes on the Drosophila phylogeny. 
  • Evolutionary and ecological functional genomics. 
  • Evolutionary genomics and adaptive evolution of the Hedgehog gene family (Shh, Ihh and Dhh) in vertebrates. 
  • Exercise biology and medicine: innovative research to improve global health. 
  • Exploring the perioptome: the role of genomics in thoracic surgery and anaesthesia. 
  • Factors affecting reproducibility between genome-scale siRNA-based screens. 
  • Finding our way through phenotypes. 
  • For better or worse: genomic consequences of intracellular mutualism and parasitism. 
  • Forward genetic approaches in Chlamydia trachomatis. 
  • From genotype to phenotype: systems biology meets natural variation. 
  • Functional Genomic Analyses of Mendelian and Sporadic Disease Identify Impaired eIF2α Signaling as a Generalizable Mechanism for Dystonia. 
  • Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli. 
  • Functional genomics approach for the identification of human host factors supporting dengue viral propagation. 
  • Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans. 
  • Functional genomics of root growth and development in Arabidopsis. 
  • Functional genomics of the beta-cell: short-chain 3-hydroxyacyl-coenzyme A dehydrogenase regulates insulin secretion independent of K+ currents. 
  • Functional interaction between responses to lactic acidosis and hypoxia regulates genomic transcriptional outputs. 
  • Functional nanostructures from surface chemistry patterning. 
  • Fungal diagnostics in pneumonia. 
  • Future translational applications from the contemporary genomics era: a scientific statement from the American Heart Association. 
  • GOBASE--a database of organelle and bacterial genome information. 
  • Gene loss, adaptive evolution and the co-evolution of plumage coloration genes with opsins in birds. 
  • Genetic diagnosis of autism spectrum disorders: the opportunity and challenge in the genomics era. 
  • Genetic dissection of the mouse CNS using magnetic resonance microscopy. 
  • Genetic effects in the leukotriene biosynthesis pathway and association with atherosclerosis. 
  • Genetic linkage study of high-grade myopia in a Hutterite population from South Dakota. 
  • Genetic markers: progress and potential for cardiovascular disease. 
  • Genetic simulation tools for post-genome wide association studies of complex diseases. 
  • Genetics, genomics, proteomics: what is a cardiologist to do? 
  • Genome engineering: the next genomic revolution. 
  • Genome evolution in bacterial endosymbionts of insects. 
  • Genome-scale analysis of anti-metabolite directed strain engineering. 
  • Genome-wide Association Study of Vein Graft Disease Following Coronary Artery Bypass Surgery 
  • Genome-wide association studies in Africans and African Americans: expanding the framework of the genomics of human traits and disease. 
  • Genome-wide high-resolution mapping of chromosome fragile sites in Saccharomyces cerevisiae. 
  • Genome-wide identification and predictive modeling of tissue-specific alternative polyadenylation. 
  • Genome-wide mapping of DNase hypersensitive sites using massively parallel signature sequencing (MPSS). 
  • Genomic Characterization of the Evolutionary Potential of the Sea Urchin Strongylocentrotus droebachiensis Facing Ocean Acidification. 
  • Genomic Views of Transcriptional Enhancers: Essential Determinants of Cellular Identity and Activity-Dependent Responses in the CNS. 
  • Genomic analyses: a neonatology perspective. 
  • Genomic analysis of the chromosome 15q11-q13 Prader-Willi syndrome region and characterization of transcripts for GOLGA8E and WHCD1L1 from the proximal breakpoint region. 
  • Genomic ancestry and somatic alterations correlate with age at diagnosis in Hispanic children with B-cell acute lymphoblastic leukemia. 
  • Genomic and molecular profiling predicts response to temozolomide in melanoma. 
  • Genomic approaches for understanding the genetics of complex disease. 
  • Genomic divergence and brain evolution: How regulatory DNA influences development of the cerebral cortex. 
  • Genomic medicine: bringing biomarkers to clinical medicine. 
  • Genomic medicine: genetic variation and its impact on the future of health care. 
  • Genomic resources for the endangered Hawaiian honeycreepers. 
  • Genomic risk profiling: attitudes and use in personal and clinical care of primary care physicians who offer risk profiling. 
  • Genomic signatures of diet-related shifts during human origins. 
  • Genomic signatures of intracellularity: Evolutionary patterns and paces in bacterial mutualists and parasites. 
  • Genomic stratification for the treatment of lymphomas. 
  • Genomics and biology come together to fight HIV. 
  • Genomics and clinical medicine: rationale for creating and effectively evaluating animal models. 
  • Genomics and expression profiles of the Hedgehog and Notch signaling pathways in sea urchin development. 
  • Genomics and the circulation. 
  • Genomics of human health and aging. 
  • Genomics of varicose veins and chronic venous insufficiency. 
  • Genomics-enabled drug repositioning and repurposing: insights from an IOM Roundtable activity. 
  • Genomics. Genomics, biobanks, and the trade-secret model. 
  • Getting to the root of plant biology: impact of the Arabidopsis genome sequence on root research. 
  • Health coaching and genomics-potential avenues to elicit behavior change in those at risk for chronic disease: protocol for personalized medicine effectiveness study in air force primary care. 
  • High-resolution genome-wide in vivo footprinting of diverse transcription factors in human cells. 
  • Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. 
  • Identification and characterization of a new cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody. 
  • Identification of cis-suppression of human disease mutations by comparative genomics. 
  • Identification of functional elements and regulatory circuits by Drosophila modENCODE. 
  • IgA and IgG antineutrophil cytoplasmic antibody engagement of Fc receptor genetic variants influences granulomatosis with polyangiitis. 
  • Imaging genetics of brain longevity and mental wellness: the next frontier? 
  • Impact of delivery models on understanding genomic risk for type 2 diabetes. 
  • In vivo modeling of the morbid human genome using Danio rerio. 
  • Independent ancient polyploidy events in the sister families Brassicaceae and Cleomaceae. 
  • Information-seeking and sharing behavior following genomic testing for diabetes risk. 
  • Initial sequencing and comparative analysis of the mouse genome. 
  • Insights and inferences about integron evolution from genomic data. 
  • Insights from a chimpanzee adipose stromal cell population: opportunities for adult stem cells to expand primate functional genomics. 
  • Integrated functional networks of process, tissue, and developmental stage specific interactions in Arabidopsis thaliana. 
  • Integrated genomic analyses identify ERRFI1 and TACC3 as glioblastoma-targeted genes. 
  • Integrated genomic characterization of endometrial carcinoma. 
  • Integrated genomic characterization of oesophageal carcinoma. 
  • Integrated metabolomics and genomics: systems approaches to biomarkers and mechanisms of cardiovascular disease. 
  • Integrated modeling of clinical and gene expression information for personalized prediction of disease outcomes. 
  • Integrating genetic and gene expression evidence into genome-wide association analysis of gene sets. 
  • Integration of Genome-Wide MicroRNA and mRNA Expression Profiles in Pulmonary Arterial Hypertension and Pulmonary Hypertension Associated with Idiopathic Pulmonary Fibrosis 
  • Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease. 
  • Integrative systems biology: an attempt to describe a simple weed. 
  • Joint learning from multiple types of genomic data. 
  • Kaposi's sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cells. 
  • Knowledge about genomic recurrence risk testing among breast cancer survivors. 
  • Letter to the editor: Standardization of genetic association studies, pros and cons, reaffirmed. 
  • Lipid Reduction Measurements in a Veteran Population - Implications for Genetic Modeling in the Million Veteran Program 
  • Liver genomic responses to ciguatoxin: evidence for activation of phase I and phase II detoxification pathways following an acute hypothermic response in mice. 
  • Making Personalized Health Care Even More Personalized: Insights From Activities of the IOM Genomics Roundtable. 
  • Managing incidental genomic findings in clinical trials: fulfillment of the principle of justice. 
  • Mapping nucleosome positions using DNase-seq. 
  • Medical genomics: Gather and use genetic data in health care. 
  • Merging Electronic Health Record Data and Genomics for Cardiovascular Research: A Science Advisory From the American Heart Association. 
  • Mesenchymal stem cells use integrin beta1 not CXC chemokine receptor 4 for myocardial migration and engraftment. 
  • Metabolomics applied to diabetes research: moving from information to knowledge. 
  • Molecular and genetic markers in thoracic surgery. 
  • Molecular genetic testing and the future of clinical genomics. 
  • Mouse models of human non-small-cell lung cancer: raising the bar. 
  • Multi-marker strategies in heart failure: clinical and statistical approaches. 
  • Multilocus patterns of nucleotide diversity, population structure and linkage disequilibrium in Boechera stricta, a wild relative of Arabidopsis. 
  • Multiregional Radiogenomic Assessment of Prostate Microenvironments with Multiparametric MR Imaging and DNA Whole-Exome Sequencing of Prostate Glands with Adenocarcinoma. 
  • NEIBank: genomics and bioinformatics resources for vision research. 
  • Network-assisted genetic dissection of pathogenicity and drug resistance in the opportunistic human pathogenic fungus Cryptococcus neoformans. 
  • Neuropsychiatric genomics in precision medicine: diagnostics, gene discovery, and translation. 
  • New insights into gestational glucose metabolism: lessons learned from 21st century approaches. 
  • New paradigms in cardiovascular medicine: emerging technologies and practices: perioperative genomics. 
  • Next generation disparities in human genomics: concerns and remedies. 
  • Omics meet networks - using systems approaches to infer regulatory networks in plants. 
  • Open window: when easily identifiable genomes and traits are in the public domain. 
  • Organellar phylogenomics of an emerging model system: Sphagnum (peatmoss). 
  • Organizational improvements to enhance modern clinical epidemiology. 
  • Outcome of Whole Exome Sequencing for Diagnostic Odyssey Cases of an Individualized Medicine Clinic: The Mayo Clinic Experience. 
  • PBmice: an integrated database system of piggyBac (PB) insertional mutations and their characterizations in mice. 
  • Parallel assay of oxygen equilibria of hemoglobin. 
  • Partial shotgun sequencing of the Boechera stricta genome reveals extensive microsynteny and promoter conservation with Arabidopsis. 
  • Pediatric ethics in the age of molecular medicine. 
  • Performance assessment of promoter predictions on ENCODE regions in the EGASP experiment. 
  • Personalized health care in 2013: a status report on the impact of genomics. 
  • Personalized health care: from theory to practice. 
  • Personalized targeted therapy for esophageal squamous cell carcinoma. 
  • Perspective: Prospective health care and the role of academic medicine: lead, follow, or get out of the way. 
  • Perspectives from the Avian Phylogenomics Project: Questions that Can Be Answered with Sequencing All Genomes of a Vertebrate Class. 
  • Pharmacogenetics at 50: genomic personalization comes of age. 
  • Pharmacogenomics and end-organ susceptibility to injury in the perioperative period. 
  • Pharmacometabolomics reveals racial differences in response to atenolol treatment. 
  • Phylogenomic analyses data of the avian phylogenomics project. 
  • Phylogeny and evolution of aldehyde dehydrogenase-homologous folate enzymes. 
  • Physiological Genomics: Who we are and where we're going. 
  • Physiological genomics of cardiac disease: quantitative relationships between gene expression and left ventricular hypertrophy. 
  • Physiological genomics of human arteries: quantitative relationship between gene expression and arterial stiffness. 
  • Platelets from genome to proteome and beyond. 
  • Population perspectives on functional genomic variation in yeast. 
  • Precision medicine for psychopharmacology: a general introduction. 
  • Prediction of a time-to-event trait using genome wide SNP data. 
  • Preface to the special issue: ecological and evolutionary genomics of populations in nature. 
  • Primary role for endoplasmic reticulum-bound ribosomes in cellular translation identified by ribosome profiling. 
  • Primate comparative genomics: lemur biology and evolution. 
  • Prognostic modeling in early stage lung cancer: an evolving process from histopathology to genomics. 
  • Prospective care: a personalized, preventative approach to medicine. 
  • Prospective health care: the second transformation of medicine. 
  • Prospective medicine: the role for genomics in personalized health planning. 
  • Prospects for personalized cardiovascular medicine: the impact of genomics. 
  • Proteomic profiling of patient-derived glioblastoma xenografts identifies a subset with activated EGFR: implications for drug development. 
  • Public health. Genomics and medicine at a crossroads in Chernobyl. 
  • Public knowledge of and attitudes toward genetics and genetic testing. 
  • Public perspectives on returning genetics and genomics research results. 
  • Public perspectives regarding data-sharing practices in genomics research. 
  • Purine synthesis promotes maintenance of brain tumor initiating cells in glioma. 
  • Radiogenomic analysis of breast cancer: luminal B molecular subtype is associated with enhancement dynamics at MR imaging. 
  • Radiogenomics: what it is and why it is important. 
  • Randomized trial of personal genomics for preventive cardiology: design and challenges. 
  • Realizing the Full Potential of Precision Medicine in Health and Health Care. 
  • Realizing the opportunities of genomics in health care. 
  • Reclassification of cardiovascular risk using integrated clinical and molecular biosignatures: Design of and rationale for the Measurement to Understand the Reclassification of Disease of Cabarrus and Kannapolis (MURDOCK) Horizon 1 Cardiovascular Disease Study. 
  • Recombineering to homogeneity: extension of multiplex recombineering to large-scale genome editing. 
  • Reconstruction of gross avian genome structure, organization and evolution suggests that the chicken lineage most closely resembles the dinosaur avian ancestor. 
  • Redefining heart failure: the utility of genomics. 
  • Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii. 
  • Report on the 6th African Society of Human Genetics (AfSHG) Meeting, March 12-15, 2009, Yaounde, Cameroon. 
  • Residual dipolar couplings: synergy between NMR and structural genomics. 
  • Response to Rosenberg et al. 
  • Revolution and renaissance. 
  • Robust regression analysis of copy number variation data based on a univariate score. 
  • Role of natural product diversity in chemical biology. 
  • SCALEs: multiscale analysis of library enrichment. 
  • SMRT Sequencing for Parallel Analysis of Multiple Targets and Accurate SNP Phasing. 
  • Sacrifice, individuation, and the economies of genomics. 
  • Sample type bias in the analysis of cancer genomes. 
  • Searching for genes that matter in acute kidney injury: a systematic review. 
  • Secrets of the perioptome: new tools for a new concept. 
  • Selecting taxa to save or sequence: desirable criteria and a greedy solution. 
  • Selection of optimal reference genes for normalization in quantitative RT-PCR. 
  • Sequencing three crocodilian genomes to illuminate the evolution of archosaurs and amniotes 
  • Sphagnum physiology in the context of changing climate: emergent influences of genomics, modelling and host-microbiome interactions on understanding ecosystem function. 
  • Statistical Viewer: a tool to upload and integrate linkage and association data as plots displayed within the Ensembl genome browser. 
  • Statistical challenges in preprocessing in microarray experiments in cancer. 
  • Strengthening the reporting of Genetic RIsk Prediction Studies (GRIPS): explanation and elaboration. 
  • Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration. 
  • Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration. 
  • Stringent comparative sequence analysis reveals SOX10 as a putative inhibitor of glial cell differentiation. 
  • Subgroup-specific structural variation across 1,000 medulloblastoma genomes. 
  • Synthetic lethal analysis of Caenorhabditis elegans posterior embryonic patterning genes identifies conserved genetic interactions. 
  • TBestDB: a taxonomically broad database of expressed sequence tags (ESTs). 
  • Test-Retest Reliability of the Genetics and Genomics in Nursing Practice Survey Instrument. 
  • The ABC's of comparative genomics in the Brassicaceae: building blocks of crucifer genomes. 
  • The DNA sequence and biological annotation of human chromosome 1. 
  • The DNA sequence of the human X chromosome. 
  • The Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH) study protocol. 
  • The Global Synanthrome Project: A Call for an Exhaustive Study of Human Associates. 
  • The IGNITE network: a model for genomic medicine implementation and research. 
  • The MetJ regulon in gammaproteobacteria determined by comparative genomics methods. 
  • The NEXT-1 (Next generation pErsonalized tX with mulTi-omics and preclinical model) trial: prospective molecular screening trial of metastatic solid cancer patients, a feasibility analysis. 
  • The Psychiatric Genomics Consortium Posttraumatic Stress Disorder Workgroup: Posttraumatic Stress Disorder Enters the Age of Large-Scale Genomic Collaboration. 
  • The dangers of diagnostic monopolies. 
  • The discovery of microdeletion syndromes in the post-genomic era: review of the methodology and characterization of a new 1q41q42 microdeletion syndrome. 
  • The future of Physiological Genomics. 
  • The genomic analysis of erythrocyte microRNA expression in sickle cell diseases. 
  • The genomic analysis of lactic acidosis and acidosis response in human cancers. 
  • The genomic landscape of mantle cell lymphoma is related to the epigenetically determined chromatin state of normal B cells. 
  • The genomics education partnership: successful integration of research into laboratory classes at a diverse group of undergraduate institutions. 
  • The impact of genomics on the biotechnology industry. 
  • The integrated landscape of driver genomic alterations in glioblastoma. 
  • The integration of molecular diagnostics with therapeutics. Implications for drug development and pathology practice. 
  • The lemur revolution starts now: the genomic coming of age for a non-model organism. 
  • The new age of medical genomics. 
  • The origin of extracellular DNA during the clearance of dead and dying cells. 
  • The performance of ZDOCK and ZRANK in rounds 6-11 of CAPRI. 
  • The value of population-based studies in the genomic era. 
  • The virulence of human pathogenic fungi: notes from the South of France. 
  • Thrombomodulin Variants are Associated with Increased Mortality following CABG Surgery in Replicated Analyses 
  • Towards integrated clinico-genomic models for personalized medicine: combining gene expression signatures and clinical factors in breast cancer outcomes prediction. 
  • Towards structural genomics of RNA: rapid NMR resonance assignment and simultaneous RNA tertiary structure determination using residual dipolar couplings. 
  • Transcriptome analysis reveals novel patterning and pigmentation genes underlying Heliconius butterfly wing pattern variation. 
  • Translating genomic biomarkers into clinically useful diagnostics. 
  • Translating the genomics revolution: the need for an international gene therapy consortium for monogenic diseases. 
  • Translational Bioinformatics: Past, Present, and Future. 
  • Uncoupling of genomic and epigenetic signals in the maintenance and inheritance of heterochromatin domains in fission yeast. 
  • Unequal representation of genetic variation across ancestry groups creates healthcare inequality in the application of precision medicine. 
  • Unisexual reproduction drives meiotic recombination and phenotypic and karyotypic plasticity in Cryptococcus neoformans. 
  • Unlocking the secrets of the genome. 
  • Unraveling the dynamic transcriptome. 
  • Virulence determinants in the obligate intracellular pathogen Chlamydia trachomatis revealed by forward genetic approaches. 
  • WGAViewer: software for genomic annotation of whole genome association studies. 
  • What was old is new again: using the host response to diagnose infectious disease. 
  • Who owns the genome? 
  • Whole blood gene expression analyses in patients with single versus recurrent venous thromboembolism. 
  • Whole-exome sequencing in undiagnosed genetic diseases: interpreting 119 trios. 
  • Worms and flies as genetically tractable animal models to study host-pathogen interactions. 
  • cnvCapSeq: detecting copy number variation in long-range targeted resequencing data. 
  • siRNA-based approaches in cancer therapy. 
• 

  Keywords of People

  • Aballay, Alejandro, Adjunct Professor in the Department of Molecular Genetics and Microbiology, Molecular Genetics and Microbiology
  • Baugh, L. Ryan, Associate Professor of Biology, Biology
  • Berchuck, Andrew, James M. Ingram Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Cho, Alex Han, Assistant Professor of Medicine, Medicine, General Internal Medicine
  • Hartemink, Alexander J., Professor in the Department of Computer Science, Computer Science
  • Kearney, Hutton Moore, Assistant Consulting Professor in the Department of Pathology, Pathology
  • MacFall, James R., Adjunct Professor in the Department of Radiology, Radiology
  • Magwene, Paul Mitaari, Associate Professor of Biology, Biology
  • McLendon, Roger Edwin, Professor of Pathology, Pathology
  • Mitchell-Olds, Thomas, Newman Ivey White Professor of Biology in Trinity College of Arts and Sciences, Biology
  • Noor, Mohamed A. F., Professor of Biology, Biology
  • Orlando, Lori Ann, Associate Professor of Medicine, Medicine, General Internal Medicine
  • Patel, Uptal Dinesh, Adjunct Professor in the Department of Medicine, Medicine, Nephrology
  • Reddy, Timothy E, Assistant Professor of Biostatistics & Bioinformatics, Biomedical Engineering
  • Svetkey, Laura Pat, Professor of Medicine, Medicine
  • Tsalik, Ephraim, Associate Professor of Medicine, Molecular Genetics and Microbiology
  • Wald, Priscilla, R. Florence Brinkley Professor of English, Duke Science & Society
  • Wernegreen, Jennifer Jo, Associate Professor of Environmental and Evolutionary Genomics in the Division of Environmental Sciences and Policy, Environmental Sciences and Policy
  • Wray, Gregory Allan, Professor of Biology, Evolutionary Anthropology
  • Yan, Hai, Henry S. Friedman Professor of Neuro-Oncology in the School of Medicine, Pathology
  • Yoder, Anne Daphne, Braxton Craven Professor of Evolutionary Biology, Duke Science & Society