Muscle Development

• 

  Subject Areas on Research

  • AT2 receptor and vascular smooth muscle cell differentiation in vascular development. 
  • Aging of skeletal muscle: a 12-yr longitudinal study. 
  • An HMGA2-IGF2BP2 axis regulates myoblast proliferation and myogenesis. 
  • Angiopoietin-1 enhances skeletal muscle regeneration in mice. 
  • Antisense technology to block autocrine growth factors. 
  • Autocrine phosphorylation of p70(S6k) in response to acute stretch in myotubes. 
  • Biomimetic engineered muscle with capacity for vascular integration and functional maturation in vivo. 
  • Calcium accumulation by isolated sarcoplasmic reticulum of skeletal muscle during development in tissue culture. 
  • Cell Density and Joint microRNA-133a and microRNA-696 Inhibition Enhance Differentiation and Contractile Function of Engineered Human Skeletal Muscle Tissues. 
  • Chicken perinatal troponin Ts are generated by a combination of novel and phylogenetically conserved alternative splicing pathways. 
  • Conditions that promote primary human skeletal myoblast culture and muscle differentiation in vitro. 
  • Control of Skeletal Muscle Cell Growth and Size Through Adhesion GPCRs. 
  • Control of muscle formation by the fusogenic micropeptide myomixer. 
  • Coordinate synthesis of two myosins in wild-type and mutant nematode muscle during larval development. 
  • Development of craniofacial musculature in Monodelphis domestica (Marsupialia, Didelphidae). 
  • Development of fast singing muscles in a katydid. 
  • Development-dependent disappearance of caspase-3 in skeletal muscle is post-transcriptionally regulated. 
  • Developmental expression of the glucose-dependent insulinotropic polypeptide gene in rat intestine. 
  • Different ontogeny of rate of force generation and shortening velocity in guinea pig trachealis. 
  • Differential effects of toll-like receptor stimulation on mRNA-driven myogenic conversion of human and mouse fibroblasts. 
  • Directed in vitro myogenesis of human embryonic stem cells and their in vivo engraftment. 
  • Distinct and overlapping sarcoma subtypes initiated from muscle stem and progenitor cells. 
  • Does transendocardial injection of mesenchymal stem cells improve myocardial function locally or globally?: An analysis from the Percutaneous Stem Cell Injection Delivery Effects on Neomyogenesis (POSEIDON) randomized trial. 
  • Dynamic regulation of sarcoplasmic reticulum Ca(2+) stores by stromal interaction molecule 1 and sarcolipin during muscle differentiation. 
  • Early de novo DNA methylation and prolonged demethylation in the muscle lineage. 
  • Effect of maturational changes in myosin content and morphometry on airway smooth muscle contraction. 
  • Enhanced MyoD-induced transdifferentiation to a myogenic lineage by fusion to a potent transactivation domain. 
  • Expression of the AT2 receptor developmentally programs extracellular signal-regulated kinase activity and influences fetal vascular growth. 
  • Gene expression during normal and FSHD myogenesis. 
  • Heparin mimicking polymer promotes myogenic differentiation of muscle progenitor cells. 
  • Human and mouse skeletal muscle stem cells: convergent and divergent mechanisms of myogenesis. 
  • Identification of distinct non-myogenic skeletal-muscle-resident mesenchymal cell populations. 
  • In vitro and in vivo osteoblastic differentiation of BMP-2- and Runx2-engineered skeletal myoblasts. 
  • Inhibition of inflammatory CCR2 signaling promotes aged muscle regeneration and strength recovery after injury. 
  • Inhibition of the Notch-Hey1 axis blocks embryonal rhabdomyosarcoma tumorigenesis. 
  • Insights into muscle stem cell dynamics during postnatal development. 
  • Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B-cell differentiation. 
  • Maturation of acetylcholinesterase expression in tracheal smooth muscle contraction. 
  • Molecular biology in cardiology: recent developments and opportunities for clinical applications. 
  • Muscle force development after low-frequency magnetic burst stimulation in dogs. 
  • MyoD, modularity, and myogenesis: conservation of regulators and redundancy in C. elegans. 
  • Myogenic Progenitor Cell Lineage Specification by CRISPR/Cas9-Based Transcriptional Activators. 
  • Myogenic transcription factors regulate pro-metastatic miR-182. 
  • Novel and effective gene transfer technique for study of vascular renin angiotensin system. 
  • Oesophageal and sternohyal muscle fibres are novel Pax3-dependent migratory somite derivatives essential for ingestion. 
  • Ontogenic expression of acetylcholinesterase activity in trachealis of young swine. 
  • Ontogeny of shortening velocity in porcine trachealis. 
  • PIP5K1α promotes myogenic differentiation via AKT activation and calcium release. 
  • Post-transcriptional regulation of myotube elongation and myogenesis by Hoi Polloi. 
  • Postnatal development and plasticity of specialized muscle fiber characteristics in the hindlimb. 
  • Prepubertal skeletal muscle growth requires Pax7-expressing satellite cell-derived myonuclear contribution. 
  • RASSF4 is required for skeletal muscle differentiation. 
  • Recent Insights into Notch Signaling in Embryonal Rhabdomyosarcoma. 
  • Requirement for reactive oxygen species in serum-induced and platelet-derived growth factor-induced growth of airway smooth muscle. 
  • Role of AP-1 complex in angiotensin II-mediated transforming growth factor-beta expression and growth of smooth muscle cells: using decoy approach against AP-1 binding site. 
  • Runx2/Cbfa1 stimulates transdifferentiation of primary skeletal myoblasts into a mineralizing osteoblastic phenotype. 
  • SOCS1, SOCS3, and PIAS1 promote myogenic differentiation by inhibiting the leukemia inhibitory factor-induced JAK1/STAT1/STAT3 pathway. 
  • STIM1-Ca(2+) signaling is required for the hypertrophic growth of skeletal muscle in mice. 
  • Smoothelin-like 1 deletion enhances myogenic reactivity of mesenteric arteries with alterations in PKC and myosin phosphatase signaling. 
  • Structural and functional development of cricket ring muscles. 
  • Subacute limb ischemia induces skeletal muscle injury in genetically susceptible mice independent of vascular density. 
  • Synergistic interactions between heterologous upstream activation elements and specific TATA sequences in a muscle-specific promoter. 
  • Synergizing Engineering and Biology to Treat and Model Skeletal Muscle Injury and Disease 
  • Temporal mechanisms of myogenic specification in human induced pluripotent stem cells. 
  • The AMPK/p27Kip1 Axis Regulates Autophagy/Apoptosis Decisions in Aged Skeletal Muscle Stem Cells. 
  • The Composition, Development, and Regeneration of Neuromuscular Junctions. 
  • The angiotensin II type 2 (AT2) receptor antagonizes the growth effects of the AT1 receptor: gain-of-function study using gene transfer. 
  • The effects of chloroquine on chick skeletal muscle in vitro. 
  • The role of mechanical and humoral factors in growth regulation of vascular smooth muscle and cardiac myocytes. 
  • Three-dimensional tissue-engineered human skeletal muscle model of Pompe disease. 
  • Transcription Factor-Directed Re-wiring of Chromatin Architecture for Somatic Cell Nuclear Reprogramming toward trans-Differentiation. 
  • Transient expression of a winged-helix protein, MNF-beta, during myogenesis. 
  • Transitions from fetal to fast troponin T isoforms are coordinated with changes in tropomyosin and alpha-actinin isoforms in developing rabbit skeletal muscle. 
  • Use of a revascularized, tubed costal myoperiosteal graft for repair of circumferential, segmental tracheal defects. 
  • WNT3A promotes myogenesis of human embryonic stem cells and enhances in vivo engraftment.