Potassium Channels, Inwardly Rectifying
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Subject Areas on Research
- Activation of the cloned muscarinic potassium channel by G protein beta gamma subunits.
- Altering integrin engagement regulates membrane localization of Kir2.1 channels.
- Block of Kir channels by flonicamid disrupts salivary and renal excretion of insect pests.
- Control of the postmating behavioral switch in Drosophila females by internal sensory neurons.
- Differential renal distribution of NHERF isoforms and their colocalization with NHE3, ezrin, and ROMK.
- Evidence that direct binding of G beta gamma to the GIRK1 G protein-gated inwardly rectifying K+ channel is important for channel activation.
- Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function.
- Inhibitory and excitatory mechanisms underlying auditory responses to learned vocalizations in the songbird nucleus HVC.
- KCNJ11 variants and their effect on the association between serum potassium and diabetes risk in the Atherosclerosis Risk in Communities (ARIC) Study and Jackson Heart Study (JHS) cohorts.
- Loss of KCNJ10 protein expression abolishes endocochlear potential and causes deafness in Pendred syndrome mouse model.
- Molecular basis for interactions of G protein betagamma subunits with effectors.
- Pertussis-toxin-sensitive Galpha subunits selectively bind to C-terminal domain of neuronal GIRK channels: evidence for a heterotrimeric G-protein-channel complex.
- Phosphorylation and nuclear translocation of a regulator of G protein signaling (RGS10).
- Progenitor Hyperpolarization Regulates the Sequential Generation of Neuronal Subtypes in the Developing Neocortex.
- Quantitative trait locus and computational mapping identifies Kcnj9 (GIRK3) as a candidate gene affecting analgesia from multiple drug classes.
- Size and ionic currents of unexcitable cells coupled to cardiomyocytes distinctly modulate cardiac action potential shape and pacemaking activity in micropatterned cell pairs.
- The MODY1 gene HNF-4alpha regulates selected genes involved in insulin secretion.
- Vascular amyloid alters astrocytic water and potassium channels in mouse models and humans with Alzheimer's disease.