E-Box Elements

• 

  Subject Areas on Research

  • Free cholesterol accumulation in macrophage membranes activates Toll-like receptors and p38 mitogen-activated protein kinase and induces cathepsin K. 
  • Genomic regions flanking E-box binding sites influence DNA binding specificity of bHLH transcription factors through DNA shape. 
  • MYC activity mitigates response to rapamycin in prostate cancer through eukaryotic initiation factor 4E-binding protein 1-mediated inhibition of autophagy. 
  • Microarray analysis of E-box binding-related gene expression in young and replicatively senescent human fibroblasts. 
  • Sequence specificity incompletely defines the genome-wide occupancy of Myc.